{"id":92184,"date":"2023-07-24T11:00:31","date_gmt":"2023-07-24T02:00:31","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=92184"},"modified":"2023-07-24T10:25:55","modified_gmt":"2023-07-24T01:25:55","slug":"1%e5%88%86%e3%81%a7%e8%a3%85%e7%9d%80%e5%8f%af%e8%83%bd%e3%80%81%e8%85%b0%e3%81%a0%e3%81%91%e3%81%a7%e3%81%aa%e3%81%8f%e8%85%95%e3%81%ae%e8%b2%a0%e6%8b%85%e3%82%82%e8%bb%bd%e6%b8%9b%e3%81%99-2-3-4-74","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/92184","title":{"rendered":"\u65b0\u305f\u306a\u8a8d\u77e5\u75c7\u4e88\u9632\u306e\u53ef\u80fd\u6027\u3092\u767a\u898b"},"content":{"rendered":"<h1>\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u306e\u4f75\u7528\u6295\u4e0e\u304c\u30de\u30a6\u30b9\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u3092\u767a\u898b<\/h1>\n<p><strong>\u2015 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\/>\n<p><strong>\u5354\u540c\u4e73\u696d\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u4e2d\u592e\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\uff1a\u5bae\ufa11\u5e79\u751f\uff09\u3068\u65e9\u7a32\u7530\u5927\u5b66\u306f\u3001\u5b9f\u9a13\u52d5\u7269\u3067\u3042\u308b\u30de\u30a6\u30b9\u306b\u5bfe\u3057\u3066\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u5354\u540c\u4e73\u696d\u682a\u5f0f\u4f1a\u793e\u306e\u751f\u7530\u304b\u3088\u7814\u7a76\u54e1\u3001\u677e\u672c\u5149\u6674\u4e3b\u5e79\u7814\u7a76\u54e1\u3001\u65e9\u7a32\u7530\u5927\u5b66<a href=\"https:\/\/www.waseda.jp\/fhum\/\" target=\"_blank\" rel=\"noopener\">\u4eba\u9593\u79d1\u5b66\u5b66\u8853\u9662<\/a>\u306e<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100000661_ja.html\" target=\"_blank\" rel=\"noopener\">\u639b\u5c71\u6b63\u5fc3<\/a>\u6559\u6388\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306e\u6210\u679c\u3067\u3059\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u56fd\u969b\u5b66\u8853\u8a8c<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2023.1164809\/full\" target=\"_blank\" rel=\"noopener\">Frontiers in Nutrition<\/a>\u306b\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<\/strong><\/p>\n<h2>\u672c\u7814\u7a76\u306e\u30dd\u30a4\u30f3\u30c8<\/h2>\n<ul>\n<li>\u5909\u5316\u3059\u308b\u74b0\u5883\u306b\u9069\u5fdc\u3059\u308b\u80fd\u529b\u3067\u3042\u308b\u300c\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u300d\u306f\u4eba\u9593\u306e\u52a0\u9f62\u3068\u3068\u3082\u306b\u4f4e\u4e0b\u3057\u3001\u8a8d\u77e5\u75c7\u521d\u671f\u306b\u6a5f\u80fd\u969c\u5bb3\u3092\u751f\u3058\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u5354\u540c\u4e73\u696d\u682a\u5f0f\u4f1a\u793e\u3068\u5b66\u6821\u6cd5\u4eba\u65e9\u7a32\u7530\u5927\u5b66\u306f\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u98df\u54c1\u6210\u5206\u306e\u7814\u7a76\u3092\u5171\u540c\u3067\u9032\u3081\u3066\u3044\u308b\u3002<\/li>\n<li>\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u88c5\u7f6e\u3092\u7528\u3044\u305f\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306e\u8a55\u4fa1\u7cfb\u3092\u65b0\u305f\u306b\u78ba\u7acb\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u4e16\u754c\u3067\u521d\u3081\u3066\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306e\u89e3\u6790\u3092\u8178\u5185\u7d30\u83cc\u53e2\u306e\u5b9f\u9a13\u306b\u304a\u3044\u3066\u5b9f\u73fe\u3057\u305f\u3002<\/li>\n<li>\u8178\u7ba1\u5185\u3067\u30dd\u30ea\u30a2\u30df\u30f3\u3092\u7523\u751f\u3059\u308b\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\uff08Bifidobacterium animalis subsp. lactis LKM512\uff09\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u306e\u4f75\u7528\u6295\u4e0e\u3067\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u304c\u5411\u4e0a\u3057\u305f\u3002<\/li>\n<\/ul>\n<h3><strong>\u7814\u7a76\u6982\u8981<\/strong><\/h3>\n<p>\u8a8d\u77e5\u75c7\u304a\u3088\u3073\u3046\u3064\u75c5\u306a\u3069\u306e\u7cbe\u795e\u75be\u60a3\u306b\u304a\u3044\u3066\u306f\u3001\u767a\u75c7\u76f4\u524d\u304a\u3088\u3073\u521d\u671f\u6bb5\u968e\u306b\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\uff08\u5909\u5316\u3059\u308b\u74b0\u5883\u306b\u9069\u5fdc\u3059\u308b\u80fd\u529b\uff09\u304c\u6025\u6fc0\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u6700\u8fd1\u306e\u7814\u7a76\u3067\u3001\u8178\u3068\u8133\u306f\u69d8\u3005\u306a\u30b7\u30b0\u30ca\u30eb\u56e0\u5b50\u3092\u4ecb\u3057\u3066\u4e92\u3044\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u304a\u308a\uff08\u8178\u8133\u76f8\u95a2\uff09\u3001\u8178\u5185\u7d30\u83cc\u53e2\u304c\u8a8d\u77e5\u6a5f\u80fd\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u5f53\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u5148\u884c\u7814\u7a76\u3067\u3001\u6297\u751f\u7269\u8cea\u306b\u3088\u308b\u8178\u5185\u7d30\u83cc\u53e2\u306e\u64b9\u4e71\u306b\u3088\u308a\u30de\u30a6\u30b9\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\uff08Tamada et al., Front Neurosci 16: 882339, 2022\uff09\u3002<\/p>\n<p>\u5354\u540c\u4e73\u696d\u304c\u9577\u5e74\u7814\u7a76\u3092\u9032\u3081\u3066\u304d\u305f\u751f\u7406\u6d3b\u6027\u7269\u8cea\u300c\u30dd\u30ea\u30a2\u30df\u30f3\u300d\u306f\u3001\u5168\u751f\u7269\u306e\u5168\u7d30\u80de\u306b\u542b\u307e\u308c\u3001\u7d30\u80de\u306e\u5065\u5168\u6027\u306e\u7dad\u6301\u306b\u5fc5\u8981\u4e0d\u53ef\u6b20\u306a\u7269\u8cea\u3067\u3059\u3002\u5916\u56e0\u7684\u30dd\u30ea\u30a2\u30df\u30f3\u6295\u4e0e\u304c\u30de\u30a6\u30b9\u306e\u5b66\u7fd2\u8a18\u61b6\u529b\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3084\u3001\u8178\u5185\u30dd\u30ea\u30a2\u30df\u30f3\u306e\u5897\u52a0\u306b\u3088\u308a\u30de\u30a6\u30b9\u306e\u7a7a\u9593\u5b66\u7fd2\u8a18\u61b6\u529b\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u3053\u3067\u672c\u7814\u7a76\u3067\u306f\u3001\u30dd\u30ea\u30a2\u30df\u30f3\u306e\u5897\u52a0\u306b\u3088\u308a\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u53ef\u80fd\u6027\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u5f53\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u304c\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u958b\u767a\u3057\u305f\u300c\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u88c5\u7f6e\u3092\u7528\u3044\u305f\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u8a55\u4fa1\u8a66\u9a13*1\u300d\u3092\u7528\u3044\u3066\u3001\u8178\u5185\u7d30\u83cc\u53e2\u306e\u30dd\u30ea\u30a2\u30df\u30f3\u7523\u751f\u3092\u4fc3\u3059\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\uff08Bif+Arg\uff09\u306e\u4f75\u7528\u6295\u4e0e\u304c\u30de\u30a6\u30b9\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u8abf\u3079\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u306e\u7d50\u679c\u3001Bif+Arg\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u306f\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001\u74b0\u5883\u5909\u5316\u306b\u67d4\u8edf\u306b\u5bfe\u5fdc\u3067\u304d\u308b\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u7b49\u306e\u8178\u5185\u74b0\u5883\u3092\u6539\u5584\u3059\u308b\u98df\u54c1\u304c\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306b\u6709\u7528\u306a\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u6700\u521d\u306e\u5831\u544a\u3068\u306a\u308a\u307e\u3059\u3002\u4eca\u5f8c\u306f\u3053\u306e\u6210\u679c\u3092\u66f4\u306b\u767a\u5c55\u3055\u305b\u308b\u305f\u3081\u3001\u30d2\u30c8\u5fdc\u7528\u8a66\u9a13\u3068\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u6790\u7814\u7a76\u3092\u8a08\u753b\u3057\u3066\u304a\u308a\u3001\u5c06\u6765\u7684\u306b\u306f\u79d1\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u6709\u3059\u308b\u65b0\u3057\u3044\u8a8d\u77e5\u75c7\u4e88\u9632\u6226\u7565\u306e\u793e\u4f1a\u5b9f\u88c5\u3092\u76ee\u6307\u3057\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-92191\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-scaled.jpg\" alt=\"\" width=\"2560\" height=\"909\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-scaled.jpg 2560w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-610x217.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-2000x711.jpg 2000w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-768x273.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-1536x546.jpg 1536w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama1-2048x728.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<h4>\uff11\uff0e\u7814\u7a76\u4f53\u5236<\/h4>\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u5354\u540c\u4e73\u696d\u682a\u5f0f\u4f1a\u793e\u7814\u7a76\u6240\u306e\u751f\u7530\u304b\u3088\u7814\u7a76\u54e1\u3001\u677e\u672c\u5149\u6674\u4e3b\u5e79\u7814\u7a76\u54e1\u3068\u65e9\u7a32\u7530\u5927\u5b66\u4eba\u9593\u79d1\u5b66\u5b66\u8853\u9662\u306e\u639b\u5c71\u6b63\u5fc3\u6559\u6388\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u5f97\u3089\u308c\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n<h4>\uff12\uff0e\u7814\u7a76\u80cc\u666f<\/h4>\n<p>\u8a8d\u77e5\u75c7\u304a\u3088\u3073\u3046\u3064\u75c5\u306a\u3069\u306e\u7cbe\u795e\u75be\u60a3\u306b\u304a\u3044\u3066\u306f\u3001\u767a\u75c7\u76f4\u524d\u304a\u3088\u3073\u521d\u671f\u6bb5\u968e\u306b\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\uff08\u5909\u5316\u3059\u308b\u74b0\u5883\u306b\u9069\u5fdc\u3059\u308b\u80fd\u529b\uff09\u304c\u6025\u6fc0\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u3001\u8a8d\u77e5\u75c7\u306e\u767a\u75c7\u30fb\u9032\u884c\u306e\u4e88\u9632\u306e\u305f\u3081\u306e\u7814\u7a76\u306e\u6a19\u7684\u3068\u3059\u308b\u3053\u3068\u306f\u6709\u52b9\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br \/>\n\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u3001\u8178\u3068\u8133\u306f\u69d8\u3005\u306a\u30b7\u30b0\u30ca\u30eb\u56e0\u5b50\u3092\u4ecb\u3057\u3066\u4e92\u3044\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u5408\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\uff08\u8178\u8133\u76f8\u95a2\uff09\u3002\u4f8b\u3048\u3070\u3001\u8178\u5185\u7d30\u83cc\u304c\u5b58\u5728\u3057\u306a\u3044\u7121\u83cc\u30de\u30a6\u30b9\u304a\u3088\u3073\u6297\u751f\u7269\u8cea\u6295\u4e0e\u306b\u3088\u3063\u3066\u8178\u5185\u7d30\u83cc\u53e2\u306e\u652a\u4e71\u3092\u8d77\u3053\u3057\u305f\u30de\u30a6\u30b9\u306f\u3001\u884c\u52d5\u5909\u5bb9\u3084\u5b66\u7fd2\u8a18\u61b6\u969c\u5bb3\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u5354\u540c\u4e73\u696d\u304c\u9577\u5e74\u7814\u7a76\u3092\u9032\u3081\u3066\u304d\u305f\u751f\u7406\u6d3b\u6027\u7269\u8cea\u30dd\u30ea\u30a2\u30df\u30f3\u306f\u3001\u5168\u751f\u7269\u306e\u5168\u7d30\u80de\u306b\u542b\u307e\u308c\u3001\u7d30\u80de\u306e\u5065\u5168\u6027\u306e\u7dad\u6301\u306b\u4e0d\u53ef\u6b20\u306a\u7269\u8cea\u3067\u3059\u304c\u3001\u5408\u6210\u80fd\u306f\u8133\u3092\u542b\u3080\u307b\u307c\u5168\u3066\u306e\u81d3\u5668\u3067\u52a0\u9f62\u306b\u4f34\u3044\u6e1b\u5c11\u3057\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30dd\u30ea\u30a2\u30df\u30f3\u306f\u98df\u4e8b\u3084\u8178\u5185\u7d30\u83cc\u53e2\u304b\u3089\u88dc\u3046\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u30dd\u30ea\u30a2\u30df\u30f3\u3068\u8a8d\u77e5\u6a5f\u80fd\u306e\u7814\u7a76\u306f\u3001\u30dd\u30ea\u30a2\u30df\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u306e\u7d4c\u53e3\u6295\u4e0e\u304c\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u3068\u30de\u30a6\u30b9\u306e\u5b66\u7fd2\u8a18\u61b6\u529b\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6211\u3005\u3082\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccLKM512\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u306e\u4f75\u7528\u6295\u4e0e\u306b\u3088\u308a\u8178\u5185\u7d30\u83cc\u53e2\u306e\u30dd\u30ea\u30a2\u30df\u30f3\u7523\u751f\u3092\u4fc3\u3059\u3068\u3001\u9ad8\u9f62\u30de\u30a6\u30b9\u306e\u7a7a\u9593\u5b66\u7fd2\u8a18\u61b6\u529b\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306b\u5bfe\u3059\u308b\u3053\u308c\u3089\u306e\u4f75\u7528\u6295\u4e0e\u306e\u52b9\u679c\u306f\u672a\u78ba\u8a8d\u3067\u3057\u305f\u3002<br \/>\n\u672c\u7814\u7a76\u3067\u306f\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u306e\u4f75\u7528\u6295\u4e0e\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3078\u306e\u6709\u52b9\u6027\u3092\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002<\/p>\n<h4>\uff13\uff0e<b>\u8a66\u9a13\u65b9\u6cd5<\/b><\/h4>\n<h5>\u30de\u30a6\u30b9\u304a\u3088\u3073\u8a66\u6599<\/h5>\n<p>\u30de\u30a6\u30b9\uff08\u96c4\u6027\u30018\u9031\u9f62\uff09\u30922\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\uff08n=7\uff09\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\uff08Bifidobacterium animalis subsp. lacits LKM512\uff09\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u6df7\u5408\u6db2\u6295\u4e0e\u7fa4\uff08Bifal\uff0bArg\u7fa4\uff09\u307e\u305f\u306f\u3053\u308c\u3089\u3092\u61f8\u6fc1\u30fb\u6eb6\u89e3\u3057\u3066\u3044\u305f\u751f\u7406\u98df\u5869\u6c34\u306e\u6295\u4e0e\u7fa4\uff08\u5bfe\u7167\u7fa4\uff09\u3068\u3057\u307e\u3057\u305f\u3002\u305d\u308c\u305e\u308c\u306e\u7fa4\u306b\u5404\u8a66\u6599\u3092\u90313\u56de\u3001\u30c6\u30b9\u30c8\u306e9\u65e5\u524d\u304b\u3089\u80c3\u30be\u30f3\u30c7\u3092\u7528\u3044\u3066\u7d4c\u53e3\u6295\u4e0e\u3057\u307e\u3057\u305f\u3002<\/p>\n<h5>\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u8a66\u9a13<\/h5>\n<p>\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u8a55\u4fa1\u3059\u308b\u8a66\u9a13\u306f\u3001\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u30fb\u30aa\u30da\u30e9\u30f3\u30c8\u88c5\u7f6e\uff08\u56f31a\uff09\uff08\u203b1\uff09\u3092\u7528\u3044\u3066\u3001\u672c\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u958b\u767a\u6e08\u307f\u306e\u8a55\u4fa1\u6cd5\uff08Front Neurosci 16: 882339, 2022\uff09\u3092\u4e00\u90e8\u6539\u5909\u3057\u3066\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306e\u8a55\u4fa1\u6cd5\u306f\u3001\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u4e0a\u306b\u5de6\u53f3\u975e\u5bfe\u79f0\u306b4\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u914d\u7f6e\u3057\u30014\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u306e\u4e2d\u304b\u3089\u6b63\u89e3\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308c\u3070\u55dc\u597d\u6027\u304c\u9ad8\u3044\u990c\u304c\u5f97\u3089\u308c\u308b\u5831\u916c\u578b\u306e\u5b66\u7fd2\u8a18\u61b6\u8a66\u9a13\u3067\u3059\u3002<br \/>\n\u8a66\u9a13\u65b9\u6cd5\u306e\u6982\u7565\u3092\u793a\u3057\u307e\u3059\u3002\u6700\u521d\u306b\u3001\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u4e0a\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u9f3b\u3067\u30bf\u30c3\u30c1\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u300c\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u300d\u3068\u3044\u3046\u884c\u52d5\u5f62\u6210\u3092\u884c\u3044\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u5b66\u7fd2\u8a66\u9a13\u3078\u3068\u9032\u307f\u307e\u3059\u3002\u5b66\u7fd2\u8a66\u9a13\u306f\u3001\u2460\u5bfe\u89d2\u7dda\u4e0a\u3092\u4ea4\u4e92\u306b\u5165\u308c\u66ff\u308f\u308b\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u884c\u52d5\u7cfb\u5217\u306e\u7372\u5f97\u306e\u305f\u3081\u306e\u539f\u5b66\u7fd2\uff08\u5c02\u9580\u7528\u8a9e\u3067\u306fBehavioral sequencing task\u3068\u3044\u3044\u307e\u3059\uff09\u3068\u3001\u2461\u305d\u306e\u6b63\u89e3\u5bfe\u89d2\u7dda\u3068\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u3092\u5165\u308c\u66ff\u3048\u308b\u9006\u8ee2\u8ab2\u984c\u3092\u53cd\u5fa9\u3057\u3066\u884c\u3046\u5b66\u7fd2\uff08\u5c02\u9580\u7528\u8a9e\u3067\u306fSerial reversal learning\uff1d\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\uff09\u304b\u3089\u6210\u308a\u307e\u3059\uff08\u56f31b\uff09\u3002<br \/>\n\u5177\u4f53\u7684\u306b\u8aac\u660e\u3059\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5b66\u7fd2\u8a66\u9a13\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u539f\u5b66\u7fd2\u3067\u306f\u3001\u5bfe\u89d2\u7dda1\u4e0a\u306e\u30b9\u30dd\u30c3\u30c8\u304c\u6b63\u89e3\u3068\u306a\u308b\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u307e\u3059\u3002\u8a66\u9a131\u304c\u958b\u59cb\u3059\u308b\u3068\u3001\u753b\u9762\u306b4\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u304c\u70b9\u706f\u3057\u307e\u3059\u3002\u30de\u30a6\u30b9\u304c\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\uff08\u56f31\uff42\u306e\u5bfe\u89d2\u7dda1\u306e\u8a66\u9a131, \u30aa\u30ec\u30f3\u30b8\u5b9f\u7dda\u3067\u56f2\u3093\u3060\u30b9\u30dd\u30c3\u30c8\uff1b\u30aa\u30ec\u30f3\u30b8\u70b9\u7dda\u3067\u56f2\u3093\u3060\u30b9\u30dd\u30c3\u30c8\u306f\u4e0d\u6b63\u89e3\uff09\u3092\u9078\u629e\u3059\u308b\u3068\u5831\u916c\uff0810mg\u306e\u990c\uff09\u304c\u5f97\u3089\u308c\u3001\u8a66\u9a132\u3078\u3068\u9032\u307f\u307e\u3059\u3002\u8a66\u9a132\u3067\u306f\u3001\u5bfe\u89d2\u7dda1\u306e\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3068\u4e0d\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u304c\u5165\u308c\u66ff\u308f\u308a\u307e\u3059\uff08\u56f31\uff42\u306e\u5bfe\u89d2\u7dda1\u306e\u8a66\u9a132\uff0c\u65b0\u305f\u306b\u30aa\u30ec\u30f3\u30b8\u5b9f\u8df5\u3067\u56f2\u3093\u3060\u30b9\u30dd\u30c3\u30c8\u304c\u6b63\u89e3\u3068\u306a\u308b\uff09\u3002\u305d\u306e\u5f8c\u3001\u8a66\u9a131\u3068\u8a66\u9a132\u3092\u4ea4\u4e92\u306b\u7e70\u308a\u8fd4\u3057\u3001\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306b\u3042\u308b2\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u4ea4\u4e92\u306b\u9078\u629e\u3059\u308b\u3053\u3068\u3067\u5831\u916c\u304c\u5f97\u3089\u308c\u308b\u3053\u3068\u3092\u5b66\u7fd2\u3057\u307e\u3059\u3002\u3082\u3057\u3001\u4e0d\u6b63\u89e3\u3092\u9078\u629e\u3057\u305f\u5834\u5408\u3001\u6b63\u89e3\u3092\u9078\u629e\u3059\u308b\u307e\u3067\u7d99\u7d9a\u3057\u307e\u3059\u3002\u3053\u306e\u539f\u5b66\u7fd2\u306f10\u65e5\u9593\u884c\u3044\u307e\u3057\u305f\u30021\u65e5\u3042\u305f\u308a\u306e\u5b66\u7fd2\u306f\u3001150\u56de\u306e\u30c8\u30e9\u30a4\u30a2\u30eb\u9054\u6210\u3042\u308b\u3044\u306f60\u5206\u9593\u7d4c\u904e\u3057\u305f\u6642\u70b9\u3067\u7d42\u4e86\u3068\u3057\u307e\u3057\u305f\u3002<br \/>\n\u6b21\u306f\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u306e\u30b9\u30c6\u30fc\u30b8\u306b\u5165\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u6b63\u89e3\u5bfe\u89d2\u7dda\u3068\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u3092\u9006\u8ee2\u3055\u305b\u3066\u5b66\u7fd2\u3092\u884c\u3044\u307e\u3059\uff08\u56f31b, \u5bfe\u89d2\u7dda 2\u3067\u540c\u3058\u3053\u3068\u3092\u884c\u3046\uff09\u3002\u3053\u306e\u30b9\u30c6\u30fc\u30b8\u306f8\u65e5\u9593\u7d99\u7d9a\u5f8c\u306b\u518d\u9006\u8ee2\u3055\u305b\uff08\u5bfe\u89d2\u7dda1\u304c\u6b63\u89e3\u306b\u623b\u308b\uff09\u3001\u3053\u308c\u3092\u7e70\u308a\u8fd4\u3057\u307e\u3059\u3002\u3053\u306e\u3001\u6b63\u89e3\u306e\u5bfe\u89d2\u7dda\u304c\u5909\u5316\u3059\u308b\u3053\u3068\u3078\u306e\u30de\u30a6\u30b9\u306e\u9069\u5fdc\u884c\u52d5\u3092\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3068\u3057\u3066\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-92192\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1029\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-scaled.jpg 2560w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-610x245.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-2000x804.jpg 2000w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-768x309.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-1536x617.jpg 1536w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama2-2048x823.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<h6 style=\"text-align: center;\">\u56f31. \u672c\u7814\u7a76\u3067\u78ba\u7acb\u3057\u305f\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306e\u8a55\u4fa1\u30bf\u30b9\u30af<\/h6>\n<p>(a) \u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u30fb\u30aa\u30da\u30e9\u30f3\u30c8\u88c5\u7f6e\uff1a\u30d1\u30cd\u30eb\u4e0a\u306e\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3078\u306e\u9f3b\u30bf\u30c3\u30c1\u3067\u5831\u916c\uff08\u990c\uff09\u304c1\u7c92\u843d\u4e0b\u3057\u3001\u30de\u30a6\u30b9\u306f\u98df\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u5468\u56f2\u306e\u97f3\u306a\u3069\u306e\u74b0\u5883\u8981\u56e0\u3092\u906e\u65ad\u3059\u308b\u9632\u97f3\u30dc\u30c3\u30af\u30b9\u5185\u306b\u88c5\u7f6e\u3092\u5165\u308c\u8a66\u9a13\u3092\u5b9f\u65bd\u3059\u308b\u3002<br \/>\n(b) \u8a55\u4fa1\u30bf\u30b9\u30af\u6982\u8981\uff1a\u5bfe\u89d2\u7dda\u4e0a\u3092\u4ea4\u4e92\u306b\u5165\u308c\u66ff\u308f\u308b\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u884c\u52d5\u7cfb\u5217\u306e\u7372\u5f97\u306e\u305f\u3081\u306e\u539f\u5b66\u7fd2\uff08Behavioral sequencing task\uff09\u3068\u305d\u306e\u6b63\u89e3\u5bfe\u89d2\u7dda\u3068\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u3092\u5165\u308c\u66ff\u3048\u308b\u9006\u8ee2\u8ab2\u984c\u3092\u53cd\u5fa9\u3057\u3066\u884c\u3046\u5b66\u7fd2\uff08Serial reversal learning\uff1d\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\uff09\u304b\u3089\u6210\u308b\uff08\u4f8b\uff1a\u5bfe\u89d2\u7dda1\u27a1\u5bfe\u89d2\u7dda2\u27a1\u5bfe\u89d2\u7dda1\u27a1\u5bfe\u89d2\u7dda2\u3068\u7e70\u308a\u8fd4\u3059\uff09\u3002<\/p>\n<h4>\uff14\uff0e<b>\u8a66\u9a13\u7d50\u679c<\/b><\/h4>\n<h5>\u539f\u5b66\u7fd2\u306e\u6210\u7acb\uff08\u8a66\u9a13\u30eb\u30fc\u30eb\u306e\u7406\u89e3\uff09<\/h5>\n<p>\u539f\u5b66\u7fd2\u306e\u6210\u7acb\uff08\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306e2\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u4ea4\u4e92\u306b\u9078\u629e\u3059\u308b\u3068\u3044\u3046\u672c\u8a66\u9a13\u306e\u57fa\u790e\u30eb\u30fc\u30eb\u3092\u7406\u89e3\u3057\u305f\u304b\u5426\u304b\uff09\u3092\u3001\u6700\u521d\u306e\u9078\u629e\uff08\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3057\u3066\u5831\u916c\u3092\u98df\u3079\u305f\u5f8c\u3001\u6b21\u306e\u30c8\u30e9\u30a4\u30a2\u30eb\u306b\u304a\u3051\u308b\u6700\u521d\u306e\u9078\u629e\uff09\u3067\u306e\u4e0d\u6b63\u89e3\u5bfe\u89d2\u9078\u629e\u7387\u3092\u7528\u3044\u3066\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u4e0d\u6b63\u89e3\u5bfe\u89d2\u9078\u629e\u7387\u3068\u306f\u3001\u56f31b\u3067\u8aac\u660e\u3057\u307e\u3059\u3068\u3001\u5bfe\u89d2\u7dda1\u304c\u6b63\u89e3\u306e\u5834\u5408\u306b\u3001\u6b63\u89e3\u306e\u5bfe\u89d2\u7dda\u4e0a\u306b\u5b58\u5728\u3057\u306a\u3044\u9752\u4e38\u3092\u9078\u629e\u3059\u308b\u5272\u5408\u3067\u3059\u3002\u4e21\u7fa4\u5171\u306b\u521d\u65e5\u306f\u9ad8\u3044\u5024\u3092\u793a\u3057\u307e\u3057\u305f\u304c\u30012\u65e5\u76ee\u306b\u306f15\uff05\u4ee5\u4e0b\u300110\u65e5\u76ee\u306b\u306f5\uff05\u4ee5\u4e0b\u306b\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u7fa4\u9593\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f32\uff09\u3002\u3053\u308c\u306f\u3001\u4e21\u7fa4\u5171\u306b\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u8a55\u4fa1\u8a66\u9a13\u3092\u884c\u3046\u305f\u3081\u306b\u5341\u5206\u306a\u5b66\u7fd2\u5f62\u6210\uff08\u30eb\u30fc\u30eb\u306e\u7406\u89e3\uff09\u304c\u884c\u308f\u308c\u305f\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-92193\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3.jpg\" alt=\"\" width=\"445\" height=\"274\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3.jpg 2528w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3-610x375.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3-2000x1231.jpg 2000w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3-768x473.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3-1536x945.jpg 1536w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama3-2048x1261.jpg 2048w\" sizes=\"auto, (max-width: 445px) 100vw, 445px\" \/><\/p>\n<h6 style=\"text-align: center;\">\u56f32. \u539f\u5b66\u7fd2\u306b\u304a\u3051\u308b\u6700\u521d\u306e\u9078\u629e\u306b\u304a\u3051\u308b\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u9078\u629e\u7387<\/h6>\n<p>\u300c\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u4ea4\u4e92\u306b\u9078\u629e\u3059\u308b\u300d\u3068\u3044\u3046\u30eb\u30fc\u30eb\u3092\u7406\u89e3\u3059\u308b\u3068\u3001\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u306f\u306a\u304f\u306a\u308b\u3002\u3053\u306e\u30c7\u30fc\u30bf\u306f\u3001\u4e21\u7fa4\u5171\u306b\u3001\u3053\u306e\u30eb\u30fc\u30eb\u3092\u5341\u5206\u306b\u7406\u89e3\u3057\u3001\u3053\u306e\u5f8c\u306e\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u306b\u81e8\u3080\u305f\u3081\u306e\u5b66\u7fd2\u5f62\u6210\u304c\u306a\u3055\u308c\u305f\u3053\u3068\u3092\u793a\u3059\u3002\u30c7\u30fc\u30bf\u306f\u5e73\u5747\u5024\u00b1\u6a19\u6e96\u8aa4\u5dee\u3067\u793a\u3059\u3002<\/p>\n<h5>\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u3078\u306e\u9069\u5fdc<\/h5>\n<p>\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u3092\u884c\u3044\u3001\u6700\u521d\u306e\u9078\u629e\u3067\u4e0d\u6b63\u89e3\u5bfe\u89d2\u3092\u9078\u629e\u3059\u308b\u5272\u5408\uff08\u9006\u8ee2\u524d\u306e\u5bfe\u89d2\u7dda\u3092\u9078\u629e\u3059\u308b\u5272\u5408\uff1d\u76f4\u524d\u306e\u30eb\u30fc\u30eb\u306b\u5247\u3063\u305f\u884c\u52d5\u3092\u3057\u305f\u5272\u5408\uff09\u306e\u63a8\u79fb\u3092\u30b0\u30e9\u30d5\u306b\u3057\u307e\u3057\u305f\uff08\u56f33\uff09\u3002\u9006\u8ee21\u56de\u76ee\u306e\u521d\u65e5\u306b\u304a\u3044\u3066\u3001\u3053\u306e\u5024\u306f\u8a66\u9a13\u671f\u9593\u4e2d\u3067\u6700\u3082\u9ad8\u304f\u3001\u5bfe\u7167\u7fa4\u306763.7\u00b17.6%\u3001Bifal+Arg\u7fa4\u306774.8\u00b15.8%\u30012\u65e5\u76ee\u306b\u306f\u4e21\u7fa4\u3068\u3082\u7d0450\uff05\u306b\u307e\u3067\u6e1b\u5c11\u3057\u307e\u3057\u305f(\u5bfe\u7167\u7fa4:48.4\u00b14.9%, Bifal + Arg group: 50\u00b15.1%\uff09\u3002\u9006\u8ee22\u56de\u76ee\u4ee5\u964d\u3001\u521d\u65e5\u306e\u6700\u521d\u306e\u9078\u629e\u3067\u306e\u4e0d\u6b63\u89e3\u5bfe\u89d2\u9078\u629e\u7387\u306f\u5f90\u3005\u306b\u4f4e\u4e0b\u3057\u3001\u9006\u8ee23\u56de\u76ee\u521d\u65e5\u3067\u306f\u3001\u4e21\u7fa4\u3068\u3082\u78ba\u7387\u306e\u4e0a\u3067\u306f\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u30ec\u30d9\u30eb\u3067\u3042\u308b50%\uff084\u30b9\u30dd\u30c3\u30c8\u4e2d\u306e2\u30b9\u30dd\u30c3\u30c8\uff1d50\uff05\uff09\u3092\u4e0b\u56de\u308a (\u5bfe\u7167\u7fa4: 48.6 \u00b1 5.8% \u3001Bifal + Arg\u7fa4:\u00a0 41.9 \u00b1 3.5%)\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u7d71\u8a08\u5b66\u7684\u306a\u7fa4\u9593\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-92194\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-scaled.jpg\" alt=\"\" width=\"2560\" height=\"1038\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-scaled.jpg 2560w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-610x247.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-2000x811.jpg 2000w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-768x311.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-1536x623.jpg 1536w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama4-2048x830.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<h6 style=\"text-align: center;\">\u56f33. \u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u306b\u304a\u3051\u308b\u6700\u521d\u306e\u9078\u629e\u306b\u304a\u3051\u308b\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u9078\u629e\u7387<\/h6>\n<p>\u9006\u8ee2\u521d\u65e5\u306b\u6570\u5024\u304c\u9ad8\u304f\u306a\u308a\u30012\u65e5\u76ee\u306b\u306f\u5927\u5e45\u306b\u4f4e\u4e0b\u3057\u3001\u9006\u8ee23\u65e5\u76ee\u4ee5\u964d\u306f\u4f4e\u5024\u3067\u5b89\u5b9a\u3057\u305f\u3002\u307e\u305f\u3001\u9006\u8ee2\u521d\u65e5\u306e\u5024\u304c\u3001\u9006\u8ee2\u306e\u7e70\u308a\u8fd4\u3057\u3067\u5f90\u3005\u306b\u4f4e\u4e0b\u3057\u305f\u3002\u7d71\u8a08\u5b66\u7684\u306a\u7fa4\u9593\u5dee\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u30c7\u30fc\u30bf\u306f\u5e73\u5747\u5024\u00b1\u6a19\u6e96\u8aa4\u5dee\u3067\u793a\u3059\u3002<\/p>\n<h5>\u5404\u9006\u8ee2\u76f4\u5f8c\u306e200\u9078\u629e\u306e\u8a73\u7d30\u89e3\u6790<\/h5>\n<p>\u56f33\u306f\u53cd\u5fa9\u9006\u8ee2\u5b66\u7fd2\u306b\u304a\u3051\u308b1\u65e5\u306e\u8a66\u9a13\u3067\u5f97\u3089\u308c\u305f\u5168\u884c\u52d5\u3092\u96c6\u8a08\u3057\u305f\u30c7\u30fc\u30bf\u3067\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u3053\u306e\u5024\u306f\u9006\u8ee22\u65e5\u76ee\u306b\u306f\u5927\u5e45\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u9006\u8ee2\u521d\u65e5\u306e\u5b66\u7fd2\u4e2d\u306b\u30de\u30a6\u30b9\u306f\u6b63\u89e3\u5bfe\u89d2\u7dda\u306e\u9006\u8ee2\u3078\u306e\u300c\u6c17\u4ed8\u304d\u300d\u3068\u300c\u9069\u5fdc\u300d\u304c\u3042\u3063\u305f\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u3001\u9006\u8ee2\u521d\u65e5\u306e\u6700\u521d\u306e200\u9078\u629e\u306e\u884c\u52d5\u3092\u8a73\u7d30\u306b\u5206\u6790\u3057\u3001\u300c\u6c17\u4ed8\u304d\u300d\u3068\u300c\u9069\u5fdc\u300d\u306e\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u6b63\u89e3\u5bfe\u89d2\u7dda\u4e0a\u306e2\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u4ea4\u4e92\u306b\u9023\u7d9a\u3057\u3066\u9078\u629e\uff08\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\uff09\u3057\u305f\u7d2f\u7a4d\u6570\u3068\u4e0d\u6b63\u89e3\u5bfe\u89d2\u7dda\u306b\u3042\u308b2\u3064\u306e\u30b9\u30dd\u30c3\u30c8\u3092\u9023\u7d9a\u3057\u3066\u9078\u629e\uff08\u4e0d\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\uff09\u3057\u305f\u7d2f\u7a4d\u6570\u306e\u63a8\u79fb\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u8a00\u3044\u63db\u3048\u307e\u3059\u3068\u3001\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306f\u3001\u65b0\u3057\u3044\u6b63\u89e3\u884c\u52d5\uff08\u9006\u8ee2\u306b\u9069\u5fdc\u3057\u3066\u3044\u308b\u884c\u52d5\uff09\u3092\u793a\u3057\u3001\u4e0d\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306f\u3001\u9006\u8ee2\u524d\u306e\u6b63\u89e3\u306b\u57fa\u3065\u304f\u884c\u52d5\uff08\u9006\u8ee2\u306b\u9069\u5fdc\u3067\u304d\u3066\u3044\u306a\u3044\u884c\u52d5\uff09\u3092\u793a\u3057\u307e\u3059\u3002<br \/>\n\u305d\u306e\u7d50\u679c\u3001\u9006\u8ee21\uff5e\u9006\u8ee24\u3067\u306f\u7fa4\u9593\u306e\u9055\u3044\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u9006\u8ee25\u304a\u3088\u30736\u56de\u76ee\u306b\u304a\u3044\u3066\u5dee\u304c\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u3059\u306a\u308f\u3061\u9006\u8ee25\u306b\u304a\u3044\u3066\u3001\u5bfe\u7167\u7fa4\u3067\u306f150\u9078\u629e\u4ed8\u8fd1\u3067\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\u304c\u5897\u52a0\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001Bifal+Arg\u7fa4\u3067\u306f\u3001100\u9078\u629e\u4ed8\u8fd1\u3067\u5897\u52a0\u3057\u307e\u3057\u305f\uff08\u56f34a\uff09\u3002\u3055\u3089\u306b\u3001Bifal+Arg\u7fa4\u3067\u306f200\u9078\u629e\u306b\u304a\u3044\u3066\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\u304c\u4e0d\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\u3088\u308a\u9ad8\u3044\u5024\u3092\u793a\u3057\u307e\u3057\u305f\u304c\u3001\u5bfe\u7167\u7fa4\u3067\u306f\u3001\u3053\u306e\u73fe\u8c61\u306f\u307f\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u9006\u8ee26\u56de\u76ee\u3067\u306f\u3001\u5bfe\u7167\u7fa4\u306f100\u9078\u629e\u4ed8\u8fd1\u3067\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u304c\u3001Bifal+Arg\u7fa4\u3067\u306f50\u9078\u629e\u4ed8\u8fd1\u3067\u5897\u52a0\u304c\u307f\u3089\u308c\u307e\u3057\u305f\uff08\u56f34a\uff09\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u5bfe\u7167\u7fa4\u3088\u308a\u3082Bifal+Arg\u7fa4\u306e\u65b9\u304c\u9006\u8ee2\u3078\u306e\u6c17\u4ed8\u304d\u3068\u9069\u5fdc\u304c\u65e9\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-92195\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-scaled.jpg\" alt=\"\" width=\"2560\" height=\"2461\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-scaled.jpg 2560w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-610x586.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-2000x1922.jpg 2000w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-768x738.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-1536x1476.jpg 1536w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2023\/07\/kakeyama5-2048x1968.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<h6 style=\"text-align: center;\">\u56f34. Bifal+Arg\u6295\u4e0e\u304c\u9006\u8ee2\u5f8c\u306e\u6700\u521d\u306e 200\u9078\u629e\u306e\u884c\u52d5\u306b\u53ca\u307c\u3059\u5f71\u97ff<\/h6>\n<p>(a) \u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\uff08\u7dd1\u7dda\uff09\u3068\u4e0d\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u7d2f\u7a4d\u6570\uff08\u30d4\u30f3\u30af\u8272\u7dda\uff09\uff0e\u9006\u8ee25\u3067\u306f\u5bfe\u7167\u7fa4\u306f150\u9078\u629e\u4ed8\u8fd1\u3001Bifal+Arg\u7fa4\u306f100\u9078\u629e\u4ed8\u8fd1\u3067\uff08\u9752\u70b9\u7dda\uff09\u3001\u9006\u8ee26\u3067\u306f\u5bfe\u7167\u7fa4\u306f100\u9078\u629e\u4ed8\u8fd1\u3001Bifal+Arg\u7fa4\u306f50\u9078\u629e\u4ed8\u8fd1\u3067\uff08\u8d64\u70b9\u7dda\uff09\u3001\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u4e0a\u6607\u304a\u3088\u3073\u4e0d\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u6e1b\u5c11\u304c\u89b3\u6e2c\u3055\u308c\u305f\u3002<br \/>\n(b) \u9006\u8ee25\u306b\u304a\u3051\u308b\u6700\u521d\u306e100\u9078\u629e\u309220\u305a\u3064\u306e\u30d6\u30ed\u30c3\u30af\u306b\u5206\u89e3\u3057\u3001\u30d6\u30ed\u30c3\u30af\u6bce\u306e\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u5272\u5408<\/p>\n<p>\u305d\u3053\u3067\u3001\u9006\u8ee2\u306b\u6c17\u4ed8\u3044\u305f\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u3088\u308a\u6b63\u78ba\u306b\u6bd4\u8f03\u3059\u308b\u305f\u3081\u306b\u3001\u9006\u8ee25\u56de\u76ee\u521d\u65e5\u306e\u6700\u521d\u306e100\u9078\u629e\u306b\u3064\u3044\u3066\u300120\u9078\u629e\u6bce\u306b1\u30d6\u30ed\u30c3\u30af\u3068\u3057\u3066\u3001\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u5272\u5408\u3092\u89e3\u6790\u3057\u307e\u3057\u305f (\u56f34b)\u3002\u305d\u306e\u7d50\u679c\u3001Bifal+Arg\u7fa4\u306e\u6b63\u89e3\u5bfe\u89d2\u9078\u629e\u5272\u5408\u306f\u3001\u30d6\u30ed\u30c3\u30af5\uff0881\uff5e100\u56de\u76ee\u306e\u9078\u629e\uff09\u306b\u304a\u3044\u3066\u5bfe\u7167\u7fa4\u3088\u308a\u3082\u6709\u610f\u306b\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f(p = 0.026)\u3002\u3055\u3089\u306b\u3001Bifal+Arg\u7fa4\u3067\u306f\u6b63\u89e3\u5bfe\u89d2\u79fb\u52d5\u306e\u5272\u5408\u304c\u5f90\u3005\u306b\u5897\u52a0\u3057\u3001\u30d6\u30ed\u30c3\u30af4(61\uff5e80\u56de\u76ee\u306e\u9078\u629e\u3001p = 0.024) \u304a\u3088\u3073\u30d6\u30ed\u30c3\u30af5(\u9078\u629e\u80a281\uff5e100\u3001p = 0.001)\u3067\u306f\u3001\u30d6\u30ed\u30c3\u30af1(1\uff5e20\u56de\u76ee\u306e\u9078\u629e)\u3088\u308a\u3082\u6709\u610f\u306b\u9ad8\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u5bfe\u7167\u7fa4\u3067\u306f\u3001\u6709\u610f\u306a\u5897\u52a0\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u304b\u3089\u3001Bifal+Arg\u7fa4\u3067\u306f\u3001\u30d6\u30ed\u30c3\u30af4\u3001\u3064\u307e\u308a\u9006\u8ee2\u76f4\u5f8c\u306e\u6700\u521d\u306e61-80\u56de\u76ee\u306e\u9078\u629e\u306b\u304a\u3044\u3066\u3001\u6b63\u89e3\u5bfe\u89d2\u304c\u5909\u5316\u3057\u3066\u3044\u308b\u3053\u3068\u306b\u6c17\u3065\u304d\u3001\u65b0\u3057\u3044\u5bfe\u89d2\u3078\u3068\u9069\u5fdc\uff08\u884c\u52d5\u3092\u5909\u5bb9\uff09\u3055\u305b\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u307e\u305f\u3001\u9006\u8ee2\u8ab2\u984c\u30924\u56de\u7a4d\u307f\u91cd\u306d\u305f\u5f8c\u3001\u9006\u8ee25\u3067\u6210\u7e3e\u304c\u5411\u4e0a\u3057\u3001\u9006\u8ee26\u3067\u306f\u3055\u3089\u306b\u5411\u4e0a\u3057\u305f\u3053\u3068\u3084\u3001\u9006\u8ee2\u76f4\u5f8c\u306e\u308f\u305a\u304b100\u9078\u629e\u5185\u3067\u3082\u5f90\u3005\u306b\u6210\u7e3e\u304c\u5411\u4e0a\u3057\u305f\u70b9\u306f\u3001\u9006\u8ee2\u5b66\u7fd2\u3092\u7e70\u308a\u8fd4\u3057\u7d4c\u9a13\u3059\u308b\u306b\u3064\u308c\u3066\u3001\u3059\u306a\u308f\u3061\u9006\u8ee21\u304b\u30894\u307e\u3067\u306e\u7d4c\u9a13\u3092\u3082\u3068\u306b\u3001\u305d\u306e\u5909\u5316\u306e\u8a8d\u8b58\u3068\u305d\u308c\u306b\u5bfe\u3059\u308b\u6700\u9069\u306a\u884c\u52d5\u9069\u5fdc\u304c\u3088\u308a\u65e9\u671f\u306b\u73fe\u308c\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u7d4c\u9a13\u3092\u7a4d\u307f\u91cd\u306d\u308b\u3053\u3068\u306b\u3088\u308a\u5909\u5316\u3078\u306e\u9069\u5fdc\u304c\u30b9\u30e0\u30fc\u30ba\u306b\u306a\u308b\u969b\u306b\u5fc5\u8981\u306alearning-set\uff08\u203b2\uff09\u306e\u5f62\u6210\u304c\u3001Bifal+Arg\u7fa4\u306e\u30de\u30a6\u30b9\u3067\u3088\u308a\u4fc3\u9032\u3055\u308c\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4>\uff15\uff0e\u7d50\u8ad6<\/h4>\n<p>Bifal+Arg\u7fa4\u306e\u30de\u30a6\u30b9\u306f\u3001\u5bfe\u7167\u7fa4\u3088\u308a\u3082\u65e9\u304f\u30eb\u30fc\u30eb\u306e\u5909\u5316\u3092\u8a8d\u8b58\u3057\u3001\u65b0\u3057\u3044\u30eb\u30fc\u30eb\u306b\u5247\u3063\u305f\u884c\u52d5\u306b\u5207\u308a\u66ff\u3048\u308b\u3053\u3068\u3001\u3059\u306a\u308f\u3061Bifal+Arg\u306e\u6295\u4e0e\u3067\u74b0\u5883\u5909\u5316\u306b\u67d4\u8edf\u306b\u5bfe\u5fdc\u3067\u304d\u308b\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3001\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3001\u30b7\u30f3\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306a\u3069\u306e\u8178\u5185\u7d30\u83cc\u53e2\u3092\u5236\u5fa1\u3059\u308b\u30bf\u30a4\u30d7\u306e\u98df\u54c1\u306b\u304a\u3044\u3066\u3001\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u306b\u53ca\u307c\u3059\u52b9\u679c\u3092\u5b9f\u8a3c\u3057\u305f\u6700\u521d\u306e\u5831\u544a\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<h4>\uff16\uff0e\u4eca\u5f8c\u306e\u5c55\u671b<\/h4>\n<p>\u5354\u540c\u4e73\u696d\u3231\u3068\u65e9\u7a32\u7530\u5927\u5b66\u4eba\u9593\u79d1\u5b66\u5b66\u8853\u9662\u306f\u3001\u3053\u306e\u6210\u679c\u3092\u66f4\u306b\u767a\u5c55\u3055\u305b\u308b\u305f\u3081\u3001\u30d2\u30c8\u5fdc\u7528\u8a66\u9a13\u3068\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u6790\u7814\u7a76\u3092\u8a08\u753b\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u305d\u308c\u306b\u3088\u308a\u3001\u79d1\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u6709\u3059\u308b\u65b0\u3057\u3044\u8a8d\u77e5\u75c7\u4e88\u9632\u6226\u7565\u306e\u793e\u4f1a\u5b9f\u88c5\u3092\u76ee\u6307\u3057\u307e\u3059\u3002<br \/>\n\u672c\u7814\u7a76\u306e\u4e00\u90e8\u306f\u3001\u65e5\u672c\u5b66\u8853\u632f\u8208\u4f1a\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1\uff0820H00575\uff09\u306e\u652f\u63f4\u306e\u3082\u3068\u3067\u5b9f\u65bd\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n<h4>\u7528\u8a9e\u89e3\u8aac<\/h4>\n<p><strong><strong>\u6ce8\uff11\uff1a<\/strong>\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u88c5\u7f6e\u3092\u7528\u3044\u305f\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u8a55\u4fa1\u8a66\u9a13<\/strong><br \/>\n\u88c5\u7f6e\u306f\u3001\u30c1\u30e3\u30f3\u30d0\u30fc\u3001\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u3001\u98fc\u6599\u4f9b\u7d66\u88c5\u7f6e\u3001\u30ab\u30e1\u30e9\u3001\u7d66\u6c34\u74f6\u306b\u3088\u308a\u69cb\u6210\u3055\u308c\u308b\u3002\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u4e0a\u306b4\u3064\u306e\u7a74\u304c\u70b9\u706f\u3057\u3001\u30de\u30a6\u30b9\u306f\u305d\u306e\u7a74\u3092\u9f3b\u3067\u30bf\u30c3\u30c1\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u9078\u629e\u3059\u308b\u3002\u30de\u30a6\u30b9\u306e\u9078\u629e\u306f\u3001\u30bf\u30c3\u30c1\u30b9\u30af\u30ea\u30fc\u30f3\u4e0a\u306e\u8d64\u5916\u7dda\u30bb\u30f3\u30b5\u30fc\u306b\u3088\u3063\u3066\u691c\u77e5\u3055\u308c\u308b\u3002\u30de\u30a6\u30b9\u304c\u6b63\u89e3\u30b9\u30dd\u30c3\u30c8\u3092\u9078\u629e\u3059\u308b\u3068\u3001\u98fc\u6599\u4f9b\u7d66\u88c5\u7f6e\u3088\u308a\u55dc\u597d\u6027\u306e\u9ad8\u3044\u98fc\u6599\u304c\u5831\u916c\u3068\u3057\u3066\u4e0e\u3048\u3089\u308c\u3001\u5b66\u7fd2\u306b\u304a\u3051\u308b\u6b63\u306e\u5f37\u5316\u304c\u306a\u3055\u308c\u308b\u3002\u5f53\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u65b0\u3057\u304f\u958b\u767a\u3057\u305f\u8a66\u9a13\u8a55\u4fa1\u7cfb\u3067\u306f\u3001\u5b9f\u9a13\u8005\u306b\u3088\u308b\u5f37\u5236\u7d4c\u53e3\u6295\u4e0e\u3084\u63a1\u8840\u306a\u3069\u306e\u4ecb\u5165\u3092\u884c\u3063\u3066\u3082\u3001\u30aa\u30da\u30ec\u30fc\u30bf\u30fc\u30fb\u30d5\u30ea\u30fc\u3067\u5168\u81ea\u52d5\u884c\u52d5\u89e3\u6790\u30b7\u30b9\u30c6\u30e0\u3067\u3042\u308bIntelliCage\u3092\u7528\u3044\u308b\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u8a55\u4fa1\u8a66\u9a13\u3068\u540c\u7b49\u306e\u7cbe\u5ea6\u3067\u8a55\u4fa1\u3067\u304d\u308b\uff08Front Neurosci 16: 882339, 2022\uff09\u3002<\/p>\n<p><strong>\u6ce8\uff12\uff1a learning-set<\/strong><br \/>\nHarry F. Harlow\u306b\u3088\u3063\u3066\u63d0\u5531\u3055\u308c\u305f\u6982\u5ff5\u3067\u3001\u5b66\u7fd2\u306e\u65b9\u6cd5\u3092\u5b66\u3076\u3053\u3068\u3092\u610f\u5473\u3059\u308b\u3002\u65b0\u3057\u3044\u72b6\u6cc1\u306b\u7f6e\u304b\u308c\u305f\u5834\u5408\u3001\u3059\u3050\u306b\u9069\u5fdc\u3057\u3066\u884c\u52d5\u3092\u5909\u3048\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u304c\u3001\u540c\u3058\u72b6\u6cc1\u306b\u4f55\u5ea6\u3082\u7f6e\u304b\u308c\u3001\u5931\u6557\u3092\u7e70\u308a\u8fd4\u3059\u3046\u3061\u306b\u3001\u305d\u306e\u5931\u6557\u306e\u7d4c\u9a13\u3092\u901a\u3057\u3066\u3001\u5931\u6557\u3092\u6700\u5c0f\u9650\u306b\u3059\u308b\u65b9\u6cd5\u3092\u5b66\u7fd2\u3059\u308b\u3053\u3068\u3067\u3042\u308b\u3002\u5b66\u7fd2\u306e\u7e70\u308a\u8fd4\u3057\u306b\u3088\u308blearning-set\u306e\u5f62\u6210\u306b\u3088\u308a\u3001\u3059\u3050\u306b\u9069\u5fdc\u3057\u3066\u884c\u52d5\u3092\u5909\u5bb9\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3002<\/p>\n<h4>\u539f\u8457\u8ad6\u6587\u60c5\u5831<\/h4>\n<p>\u8457\u8005\uff1aKayo Ikuta, Daisuke Joho, Masaki Kakeyama and Mitsuharu Matsumoto<br \/>\n\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb\uff1a<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2023.1164809\/full\">Bifidobacterium animalis subsp. lactis and arginine mixture intake improves cognitive flexibility in mice<\/a><br \/>\n\u96d1\u8a8c\u540d\uff1aFrontiers in Nutrition 10: 1164809, 2023, doi.org\/10.3389\/fnut.2023.1164809<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3068\u30a2\u30eb\u30ae\u30cb\u30f3\u306e\u4f75\u7528\u6295\u4e0e\u304c\u30de\u30a6\u30b9\u306e\u8a8d\u77e5\u7684\u67d4\u8edf\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u3092\u767a\u898b \u2015 \u52a0\u9f62\u306b\u4f34\u3046\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u9632\u6b62\u3084\u8a8d\u77e5\u75c7\u4e88\u9632\u306e\u65b0\u305f\u306a\u53ef\u80fd\u6027 \u2015 \u5354\u540c\u4e73\u696d\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u4e2d\u592e\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\uff1a\u5bae\ufa11\u5e79\u751f\uff09\u3068\u65e9\u7a32\u7530\u5927\u5b66 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":92228,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[357,5],"class_list":["post-92184","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/92184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=92184"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/92184\/revisions"}],"predecessor-version":[{"id":92229,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/92184\/revisions\/92229"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/92228"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=92184"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=92184"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=92184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}