{"id":86071,"date":"2022-12-07T08:00:17","date_gmt":"2022-12-06T23:00:17","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=86071"},"modified":"2022-12-19T16:02:37","modified_gmt":"2022-12-19T07:02:37","slug":"%e6%9f%93%e8%89%b2%e4%bd%93%e3%81%ae%e5%bd%a2%e3%82%92%e3%82%b3%e3%83%b3%e3%83%88%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%99%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/86071","title":{"rendered":"\u67d3\u8272\u4f53\u306e\u5f62\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b"},"content":{"rendered":"

\u67d3\u8272\u4f53\u306e\u5f62\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u666e\u904d\u7684\u306a\u4ed5\u7d44\u307f\u306e\u4e00\u90e8\u3092\u89e3\u660e<\/strong><\/a><\/h1>\n

\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u65b0\u305f\u306a\u6249\u3092\u958b\u304f\u53ef\u80fd\u6027\u306b\u671f\u5f85\u304c\u9ad8\u307e\u308b<\/strong><\/h2>\n

\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/p>\n

\u7d30\u80de\u306e\u304c\u3093\u5316\u3084\u3001\u7570\u5e38\u306a\u67d3\u8272\u4f53\u6570\u3092\u53d7\u3051\u7d99\u3050\u30c0\u30a6\u30f3\u75c7\u306a\u3069\u306e\u5148\u5929\u6027\u67d3\u8272\u4f53\u7570\u5e38\u3068\u3082\u5bc6\u63a5\u306b\u7d50\u3073\u3064\u304f\u3068\u3055\u308c\u308b\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u3092\u4f5c\u308a\u51fa\u3059\u666e\u904d\u7684\u306a\u3057\u304f\u307f\u306b\u3001\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u3068\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u304c\u95a2\u308f\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u3002<\/h5>\n
\u30d2\u30c8\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306b\u304a\u3051\u308b\u9577\u3055\u3068\u592a\u3055\u306e\u9593\u306e\u51aa\uff08\u3079\u304d\uff09\u4e57\u5247\u306e\u95a2\u4fc2\u6027\uff08\u30a2\u30ed\u30e1\u30c8\u30ea\u30fc\uff09\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/h5>\n
\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u69cb\u9020\u3092\u89e3\u660e\u3057\u3001\u3053\u308c\u3092\u4eba\u5de5\u7684\u306b\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3084\u67d3\u8272\u4f53\u69cb\u9020\u306a\u3069\u306e\u4efb\u610f\u306a\u8abf\u7bc0\u30fb\u64cd\u4f5c\u3092\u5b9f\u73fe\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5c06\u6765\u7684\u306b\u306f\u793e\u4f1a\u8ab2\u984c\u306e1\u3064\u3067\u3042\u308b\u9ad8\u9f62\u4e0d\u598a\u306e\u6839\u672c\u539f\u56e0\u306e\u63a2\u7a76\u3084\u751f\u6b96\u533b\u7642\u3078\u3068\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u65b0\u305f\u306a\u6249\u3092\u958b\u304f\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/h5>\n

\"\"<\/p>\n

\u65e9\u7a32\u7530\u5927\u5b66\u9ad8\u7b49\u7814\u7a76\u6240\u306e\u89d2\u4e95\u5eb7\u8ca2\uff08\u304b\u304f\u3044\u3084\u3059\u305f\u304b\uff09\u8b1b\u5e2b<\/a>\u3001\u82f1\u56fd\u30d5\u30e9\u30f3\u30b7\u30b9\u30af\u30ea\u30c3\u30af\u7814\u7a76\u6240\u306eFrank Uhlmann\u30b0\u30eb\u30fc\u30d7\u30ea\u30fc\u30c0\u30fc\u3001\u516c\u76ca\u8ca1\u56e3\u6cd5\u4eba\u304c\u3093\u7814\u7a76\u4f1a \u304c\u3093\u7814\u7a76\u6240\u306e\u5e83\u7530\u4ea8\uff08\u3072\u308d\u305f\u3068\u304a\u308b\uff09\u90e8\u9577\u3089\u306b\u3088\u308b\u56fd\u969b\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\uff08\u4ee5\u4e0b\u3001\u672c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\uff09\u306f\u3001\u9175\u6bcd\u7d30\u80de\u30fb\u30d2\u30c8\u57f9\u990a\u7d30\u80de\u306e\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\u3001\u751f\u7269\u7a2e\u3054\u3068\u306e\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u306b\u5fdc\u3058\u3066\u5206\u88c2\u671f\u67d3\u8272\u4f53\u3092\u5f62\u4f5c\u308b\u5171\u901a\u306e\u3057\u304f\u307f\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u907a\u4f1d\u60c5\u5831\u306f\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306b\u3088\u308a\u5b89\u5168\u306b\u53d7\u3051\u7d99\u304c\u308c\u307e\u3059\u3002\u672c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u304c\u751f\u7269\u7a2e\u3054\u3068\u306e\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u306b\u5fdc\u3058\u305f\u7279\u6709\u306e\u592a\u3055\u3092\u6301\u3064\u3053\u3068\u3001\u3055\u3089\u306b\u3001\u540c\u4e00\u751f\u7269\u7a2e\u5185\u3067\u306f\u67d3\u8272\u4f53\u306e\u592a\u3055\u304c\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u306b\u3088\u308a\u898f\u5b9a\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u89e3\u660e\u306b\u3088\u3063\u3066\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u4f5c\u308a\u65b9\u306e\u65b0\u305f\u306a\u5074\u9762\u304c\u898b\u3048\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n

\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u7c73\u56fd\u306eCell Press\u793e\u304c\u767a\u884c\u3059\u308b\u300eCell Report<\/a>\u300f<\/strong>\u306b2022\u5e7412\u67086\u65e5\uff08\u706b\uff09\u5348\u524d11\u6642\uff08\u7c73\u56fd\u6771\u90e8\u6642\u9593\uff09\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u8ad6\u6587\u540d\uff1aChromosome arm length, and a species-specific determinant, define chromosome arm width.<\/a><\/p>\n

\uff08\uff11\uff09\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068\uff08\u79d1\u5b66\u53f2\u7684\u30fb\u6b74\u53f2\u7684\u306a\u80cc\u666f\u306a\u3069\uff09<\/strong><\/h3>\n

\u751f\u547d\u306e\u8a2d\u8a08\u56f3\u3067\u3042\u308b\u907a\u4f1d\u60c5\u5831\u306f\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u203b\uff11<\/sup>\u306b\u3088\u3063\u3066\u7d30\u80de\u304b\u3089\u7d30\u80de\u3078\u3068\u53d7\u3051\u7d99\u304c\u308c\u3066\u3044\u304d\u307e\u3059\u3002\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306f\u3001\u3068\u3066\u3082\u9577\u3044\u7d10\u306e\u3088\u3046\u306a\u69cb\u9020\u306e\u30b2\u30ce\u30e0DNA\u203b\uff12<\/sup>\u304c\u8907\u96d1\u306b\u6298\u308a\u7573\u307e\u308c\u305f\u7acb\u4f53\u69cb\u9020\u3092\u3082\u3061\u307e\u3059\u3002\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u969b\u306b\u306f\u3001\u30b3\u30d4\u30fc\u3055\u308c\u305f\u30b2\u30ce\u30e0DNA\u304c\u4e00\u7d44\u305a\u3064\u306e\u5206\u88c2\u671f\u67d3\u8272\u4f53\u3068\u3057\u30661\u3064\u6b8b\u3089\u305a\u78ba\u5b9f\u306b\u5206\u914d\u3055\u308c\u3001\u540c\u4e00\u306e\u907a\u4f1d\u60c5\u5831\u304c\u5a18\u7d30\u80de\u203b\uff13<\/sup>\u3078\u3068\u4f1d\u308f\u3063\u3066\u3044\u304d\u307e\u3059\u3002\u5206\u88c2\u671f\u67d3\u8272\u4f53\u304c\u4e0d\u5b8c\u5168\u306b\u5206\u914d\u3055\u308c\u308b\u3068\u3001\u5a18\u7d30\u80de\u306e\u4fdd\u6301\u3059\u308b\u907a\u4f1d\u60c5\u5831\u306b\u904e\u4e0d\u8db3\u304c\u751f\u3058\u3066\u7570\u5e38\u306a\u7d30\u80de\u304c\u751f\u307e\u308c\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u67d3\u8272\u4f53\u5206\u914d\u306f\u7d30\u80de\u306e\u304c\u3093\u5316\u3084\u3001\u7570\u5e38\u306a\u67d3\u8272\u4f53\u6570\u3092\u53d7\u3051\u7d99\u3050\u30c0\u30a6\u30f3\u75c7\u306a\u3069\u306e\u5148\u5929\u6027\u67d3\u8272\u4f53\u7570\u5e38\u3068\u3082\u5bc6\u63a5\u306b\u7d50\u3073\u3064\u304f\u305f\u3081\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u3092\u4f5c\u308a\u51fa\u3059\u3057\u304f\u307f\u3092\u89e3\u304d\u660e\u304b\u3059\u3053\u3068\u306f\u3001\u533b\u5b66\u7684\u898b\u5730\u304b\u3089\u3082\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n

\u30d2\u30c8\u3084\u9175\u6bcd\u7d30\u80de\u306a\u3069\u306e\u771f\u6838\u751f\u7269\u3067\u306f\u3001\u30b2\u30ce\u30e0DNA\u306f\u30d2\u30b9\u30c8\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5dfb\u304d\u3064\u3044\u305f\u30d3\u30fc\u30ba\u306e\u3088\u3046\u306a\u69cb\u9020\u304c\u3001\u6570\u73e0\u72b6\u306b\u7e4b\u304c\u3063\u305f\u30af\u30ed\u30de\u30c1\u30f3\u3068\u3057\u3066\u3001\u7d30\u80de\u5185\u306b\u4fdd\u6301\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30af\u30ed\u30de\u30c1\u30f3\u304c\u3055\u3089\u306b\u8907\u96d1\u306b\u6298\u308a\u7573\u307e\u308c\u3066\u3001\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u969b\u306b\u5206\u88c2\u671f\u67d3\u8272\u4f53\u3068\u306a\u308a\u307e\u3059\uff08\u56f3\uff12<\/strong>\uff09\u3002\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u7acb\u4f53\u69cb\u9020\u306f\u3001structural maintenance of chromosomes (SMC) \u8907\u5408\u4f53\u30b3\u30f3\u30c7\u30f3\u30b7\u30f3\u203b\uff14<\/sup>\u304c\u30af\u30ed\u30de\u30c1\u30f3\u3092\u30eb\u30fc\u30d7\u72b6\u306b\u675f\u306d\u308b\u3053\u3068\u3067\u5f62\u4f5c\u3089\u308c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u30df\u30af\u30ed\u306a\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u69cb\u9020\u304c\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u67d3\u8272\u4f53\u3068\u3057\u3066\u306e\u5f62\u3092\u4f5c\u308b\u306e\u304b\u306f\u3001\u3053\u308c\u307e\u3067\u660e\u3089\u304b\u306b\u306f\u306a\u3063\u3066\u304a\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n

\"\"<\/p>\n

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\uff08\uff12\uff09\u4eca\u56de\u306e\u7814\u7a76\u3067\u65b0\u305f\u306b\u5b9f\u73fe\u3057\u3088\u3046\u3068\u3057\u305f\u3053\u3068\u3001\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3053\u3068<\/h3>\n

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\u3053\u306e\u3088\u3046\u306a\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u3068\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u306e\u95a2\u4fc2\u6027\u3092\u30d2\u30c8\u57f9\u990a\u7d30\u80de\u3067\u3082\u8abf\u3079\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u67d3\u8272\u4f53\u8155\u90e8\u306e\u30b2\u30ce\u30e0DNA\u304c\u9577\u3044\u307b\u3069\u3001\u3088\u308a\u5927\u304d\u306a\u30b5\u30a4\u30ba\u306e\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u3092\u4f5c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u30b2\u30ce\u30e0DNA\u9577\u3068\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u306e\u95a2\u4fc2\u6027\u306f\u3001\u9175\u6bcd\u304b\u3089\u30d2\u30c8\u307e\u3067\u9032\u5316\u7684\u306b\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u3053\u3068\u306f\u3001\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u306b\u3088\u308b\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u30b5\u30a4\u30ba\u306e\u5236\u5fa1\u304c\u67d3\u8272\u4f53\u3092\u5f62\u4f5c\u308b\u666e\u904d\u7684\u306a\u3057\u304f\u307f\u306e\u4e00\u90e8\u3067\u3042\u308b\u3053\u3068\u3092\u5f37\u304f\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u69cb\u9020\u306f\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u57fa\u76e4\u3068\u306a\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u3082\u95a2\u308f\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306e\u7814\u7a76\u306e\u3088\u3046\u306b\u3001\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u69cb\u9020\u306b\u3064\u3044\u3066\u8abf\u3079\u308b\u3053\u3068\u306f\u3001\u30b2\u30ce\u30e0DNA\u304c\u7d30\u80de\u5185\u3067\u52d5\u4f5c\u3059\u308b\u969b\u306e\u57fa\u76e4\u3068\u306a\u308b\u539f\u7406\u306e\u89e3\u660e\u3078\u3068\u8ca2\u732e\u3057\u307e\u3059\u3002\u5c06\u6765\u7684\u306b\u306f\u3001\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u69cb\u9020\u3092\u4eba\u5de5\u7684\u306b\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3084\u67d3\u8272\u4f53\u69cb\u9020\u3092\u4efb\u610f\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u306b\u65b0\u305f\u306a\u6249\u3092\u958b\u304f\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306f\u3001\u907a\u4f1d\u60c5\u5831\u3092\u7d30\u80de\u304b\u3089\u7d30\u80de\u3078\u3068\u53d7\u3051\u7d99\u3050\u5b9f\u50cd\u90e8\u968a\u3067\u3059\u3002\u304c\u3093\u5316\u3057\u305f\u7d30\u80de\u3084\u5148\u5929\u6027\u67d3\u8272\u4f53\u7570\u5e38\u3060\u3051\u3067\u306a\u304f\u3001\u9ad8\u9f62\u306e\u5973\u6027\u304b\u3089\u63a1\u53d6\u3057\u305f\u5375\u5b50\u306b\u304a\u3044\u3066\u3082\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u304c\u69cb\u9020\u7570\u5e38\u3092\u793a\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u67d3\u8272\u4f53\u69cb\u9020\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3057\u304f\u307f\u3092\u89e3\u304d\u660e\u304b\u3059\u4eca\u56de\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u793e\u4f1a\u8ab2\u984c\u306e1\u3064\u3067\u3042\u308b\u9ad8\u9f62\u4e0d\u598a\u306e\u6839\u672c\u539f\u56e0\u306e\u63a2\u7a76\u3084\u751f\u6b96\u533b\u7642\u3078\u3068\u5c06\u6765\u7684\u306b\u7d50\u3073\u3064\u304f\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u8fd1\u5e74\u3001DNA\u3092\u8a18\u61b6\u5a92\u4f53\u3068\u3057\u3066\u30c7\u30b8\u30bf\u30eb\u30c7\u30fc\u30bf\u3092\u4fdd\u5b58\u3059\u308b\u7814\u7a76\u3082\u9032\u3093\u3067\u304d\u3066\u3044\u307e\u3059\u3002DNA\u3092\u8a18\u61b6\u5a92\u4f53\u3068\u3057\u3066\u5229\u7528\u3059\u308b\u5834\u5408\u3001\u7d30\u80de\u306e\u3088\u3046\u306b\u5c0f\u3055\u306a\u30b9\u30da\u30fc\u30b9\u306bDNA\u3092\u4e0a\u624b\u304f\u8a70\u3081\u8fbc\u307f\u3001\u305d\u3053\u304b\u3089\u8aad\u307f\u66f8\u304d\u3055\u305b\u308b\u3053\u3068\u304c\u5fc5\u8981\u3068\u306a\u3063\u3066\u304f\u308b\u3068\u4e88\u60f3\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3001\u9577\u3044DNA\u304c\u67d3\u8272\u4f53\u69cb\u9020\u3092\u5f62\u4f5c\u308b\u3057\u304f\u307f\u3092\u5fdc\u7528\u3059\u308b\u3053\u3068\u3067\u3001DNA\u306e\u8a18\u61b6\u5a92\u4f53\u3068\u3057\u3066\u306e\u6709\u7528\u6027\u304c\u9ad8\u307e\u3063\u3066\u3044\u304f\u3068\u898b\u8fbc\u307e\u308c\u307e\u3059\u3002<\/p>\n

\uff084\uff09\u4eca\u5f8c\u306e\u8ab2\u984c<\/h3>\n

\u4eca\u56de\u306e\u767a\u898b\u306b\u3088\u308a\u3001\u30b2\u30ce\u30e0DNA\u306e\u9577\u3055\u3068\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u304c\u3001\u751f\u7269\u7a2e\u3054\u3068\u306e\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u3092\u6c7a\u3081\u308b\u5171\u901a\u306e\u3057\u304f\u307f\u306e\u4e00\u90e8\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u4e00\u65b9\u3067\u3001\u751f\u7269\u7a2e\u3054\u3068\u306e\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u304c\u3069\u306e\u3088\u3046\u306a\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3001\u3068\u3044\u3046\u65b0\u305f\u306a\u8ab2\u984c\u304c\u898b\u3048\u3066\u304d\u307e\u3057\u305f\u3002\u524d\u8ff0\u306e\u3088\u3046\u306b\u3001\u30af\u30ed\u30de\u30c1\u30f3\u30eb\u30fc\u30d7\u306e\u5927\u304d\u3055\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u306f\u3001SMC\u8907\u5408\u4f53\u30b3\u30f3\u30c7\u30f3\u30b7\u30f3\u306e\u50cd\u304d\u304c\u9375\u3092\u63e1\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u306f\u3088\u308a\u8a73\u7d30\u306a\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u304d\u660e\u304b\u3057\u3066\u3044\u304d\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u4eca\u56de\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u30d2\u30c8\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306b\u304a\u3051\u308b\u9577\u3055\u3068\u592a\u3055\u306e\u30a2\u30ed\u30e1\u30c8\u30ea\u30fc\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u67d3\u8272\u4f53\u69cb\u9020\u306e\u30a2\u30ed\u30e1\u30c8\u30ea\u30fc\u304c\u30d2\u30c8\u4ee5\u5916\u306e\u751f\u7269\u7a2e\u306b\u304a\u3044\u3066\u9032\u5316\u7684\u306b\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u3053\u306e\u666e\u904d\u6027\u306b\u3064\u3044\u3066\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u304f\u3068\u3068\u3082\u306b\u3001\u30b2\u30ce\u30e0DNA\u306e\u9032\u5316\u306b\u8feb\u3063\u3066\u3044\u3051\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u6599\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff085\uff09\u7814\u7a76\u8005\u306e\u30b3\u30e1\u30f3\u30c8<\/h3>\n

\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306f\uff11\uff19\u4e16\u7d00\u672b\u306b\u30f4\u30a1\u30eb\u30bf\u30fc\u30fb\u30d5\u30ec\u30df\u30f3\u30b0\u306b\u3088\u3063\u3066\u89b3\u5bdf\u3055\u308c\u305f\u3001\u7d30\u80de\u306e\u4e2d\u3067\u6700\u3082\u5927\u304d\u306a\u69cb\u9020\u4f53\u306e1\u3064\u3067\u3059\u3002\u5206\u88c2\u671f\u67d3\u8272\u4f53\u306e\u69cb\u9020\u306f\u3001\u7e4a\u7dad\u72b6\u306e\u30af\u30ed\u30de\u30c1\u30f3\u304c\u6298\u308a\u7573\u307e\u308c\u305f\u30eb\u30fc\u30d7\u306e\u96c6\u5408\u4f53\u3067\u3042\u308b\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u672a\u3060\u306b\u305d\u306e\u5168\u5bb9\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u672c\u7814\u7a76\u3067\u306e\u767a\u898b\u3092\u8db3\u304c\u304b\u308a\u306b\u3001\u67d3\u8272\u4f53\u306e\u69cb\u9020\u3092\u5f62\u4f5c\u308b\u666e\u904d\u7684\u306a\u3057\u304f\u307f\u306b\u3001\u3055\u3089\u306b\u8e0f\u307f\u8fbc\u3093\u3067\u3044\u304d\u305f\u3044\u3067\u3059\u3002<\/p>\n

\uff086\uff09\u7528\u8a9e\u89e3\u8aac<\/h3>\n

\u203b\uff11\u3000\u5206\u88c2\u671f\u67d3\u8272\u4f53<\/h5>\n

\u7d30\u80de\u304c\u5206\u88c2\u3059\u308b\u969b\u306b\u3001\u30af\u30ed\u30de\u30c1\u30f3\u304c\u30b3\u30f3\u30d1\u30af\u30c8\u306b\u6298\u308a\u7573\u307e\u308c\u3066\u51dd\u7e2e\u3057\u3001X\u306e\u5f62\u3092\u3057\u305f\u30b2\u30ce\u30e0DNA\u306e\u69cb\u9020\u306e\u3053\u3068\u3002<\/p>\n

\u203b\uff12\u3000\u30b2\u30ce\u30e0DNA<\/h5>\n

\u30a2\u30c7\u30cb\u30f3\uff08A\uff09\u3001\u30c1\u30df\u30f3\uff08T\uff09\u3001\u30b0\u30a2\u30cb\u30f3\uff08G\uff09\u3001\u30b7\u30c8\u30b7\u30f3\uff08C\uff09\u306e4\u3064\u306e\u5869\u57fa\u304c\u7e4b\u304c\u3063\u305f\u914d\u5217\u306e\u3053\u3068\u3002A,T,G,C\u306e\uff14\u5869\u57fa\u306e\u9806\u756a\u306b\u3088\u308b\u7d44\u307f\u5408\u308f\u305b\u3092\u5229\u7528\u3057\u3066\u3001\u751f\u547d\u306f\u907a\u4f1d\u60c5\u5831\u3092\u4fdd\u5b58\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u203b\uff13\u3000\u5a18\u7d30\u80de<\/h5>\n

1\u3064\u306e\u7d30\u80de\u304c2\u3064\u306b\u5206\u88c2\u3057\u305f\u5f8c\u306b\u4f5c\u3089\u308c\u308b\u7d30\u80de\u306e\u3053\u3068\u3002<\/p>\n

\u203b\uff14\u3000structural maintenance of chromosomes (SMC) \u8907\u5408\u4f53\u30b3\u30f3\u30c7\u30f3\u30b7\u30f3<\/h5>\n

\u30d2\u30b9\u30c8\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6301\u305f\u306a\u3044\u5927\u8178\u83cc\u306a\u3069\u306e\u539f\u6838\u751f\u7269\u304b\u3089\u3001\u30d2\u30c8\u306a\u3069\u306e\u9ad8\u7b49\u771f\u6838\u751f\u7269\u307e\u3067\u9032\u5316\u7684\u306b\u5e45\u5e83\u304f\u4fdd\u5b58\u3055\u308c\u305f\u30ea\u30f3\u30b0\u72b6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u8907\u5408\u4f53\u3002\u7d30\u80de\u5185\u306b\u304a\u3044\u3066\u30af\u30ed\u30de\u30c1\u30f3\u3092\u30eb\u30fc\u30d7\u72b6\u306b\u675f\u306d\u308b\u3053\u3068\u3067\u3001\u5206\u88c2\u671f\u67d3\u8272\u4f53\u3092\u5f62\u4f5c\u308b\u3002<\/p>\n

\u203b\uff15\u3000\u30b2\u30ce\u30e0\u30b5\u30a4\u30ba<\/h5>\n

\u30b2\u30ce\u30e0DNA\u3092\u69cb\u6210\u3059\u308b\u5869\u57fa\u306e\u7dcf\u6570\u306e\u3053\u3068\u3002\u5404\u751f\u7269\u306b\u56fa\u6709\u306e\u30b2\u30ce\u30e0\u30b5\u30a4\u30ba\u3092\u3082\u3064\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u30d2\u30c8\u7d30\u80de\u3067\u306f\u7d0430\u5104\u5869\u57fa\u5bfe\u3001\u9175\u6bcd\u7d30\u80de\u3067\u306f1200\u22121400\u4e07\u5869\u57fa\u5bfe\u3067\u3042\u308b\u3002<\/p>\n

\u203b\uff16\u3000Hi-C\u6cd5<\/h5>\n

Hi-C\u6cd5\uff08high – throughput chromosome conformation capture\uff1a\u67d3\u8272\u4f53\u7acb\u4f53\u914d\u5ea7\u6355\u6349\u6cd5\uff09\u306f\u3001\u7d30\u80de\u5185\u306b\u304a\u3051\u308b\u30af\u30ed\u30de\u30c1\u30f3\u306e\u7a7a\u9593\u914d\u7f6e\u3092\u8abf\u3079\u308b\u5b9f\u9a13\u624b\u6cd5\u306e1\u3064\u3002\u30b2\u30ce\u30e0DNA\u914d\u5217\u3092\u5229\u7528\u3057\u3066\u3001\u8fd1\u63a5DNA\u914d\u5217\u3092\u7db2\u7f85\u7684\u306b\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u3067\u8aad\u307f\u53d6\u308b\u3053\u3068\u3067\u3001\u30af\u30ed\u30de\u30c1\u30f3\u306e\u7a7a\u9593\u914d\u7f6e\u3092\u6c7a\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002<\/p>\n

\u203b\uff17\u3000\u8d85\u9ad8\u89e3\u50cf\u5ea6\u86cd\u5149\u9855\u5fae\u93e1<\/h5>\n

\u901a\u5e38\u306e\u5149\u5b66\u9855\u5fae\u93e1\uff08\u86cd\u5149\u9855\u5fae\u93e1\uff09\u306f\u3001\u4f7f\u7528\u3059\u308b\u5149\u306e\u6ce2\u9577\u306b\u5fdc\u3058\u3066\u3001\u5c0f\u3055\u306a\u69cb\u9020\u7269\u306e\u898b\u3048\u65b9\uff08\u89e3\u50cf\u5ea6\uff09\u306b\u9650\u754c\u304c\u3042\u308b\u3002\u8d85\u9ad8\u89e3\u50cf\u5ea6\u86cd\u5149\u9855\u5fae\u93e1\u306f\u3001\u3053\u306e\u89e3\u50cf\u5ea6\u3088\u308a\u3082\u5fae\u7d30\u306a\u69cb\u9020\u3092\u53ef\u8996\u5316\u3067\u304d\u308b\u7279\u5225\u306a\u9855\u5fae\u93e1\u3067\u3042\u308b\u3002<\/p>\n

\uff087\uff09\u8ad6\u6587\u60c5\u5831<\/h3>\n

\u96d1\u8a8c\u540d\uff1a<\/strong>Cell Reports<\/a>
\n\u8ad6\u6587\u540d\uff1a<\/strong>Chromosome arm length, and a species-specific determinant, define chromosome arm width.<\/a>
\n\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a<\/strong>\u89d2\u4e95\u5eb7\u8ca2<\/a> 1,2,3<\/sup>\u3001Christopher Barrington 4<\/sup>\u3001\u8349\u91ce\u5584\u6674 6<\/sup>\u3001Rahul Thadani 3<\/sup>\u3001Todd Fallesen 5<\/sup>\u3001\u5e83\u7530\u4ea8 6<\/sup>\u3001Frank Uhlmann 3<\/sup><\/p>\n

\uff081.\u65e9\u7a32\u7530\u5927\u5b66 \u9ad8\u7b49\u7814\u7a76\u6240<\/a>\u30012.\u65e9\u7a32\u7530\u5927\u5b66 \u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1 \u751f\u547d\u533b\u79d1\u5b66\u79d1\u5c02\u653b<\/a>\u30013.\u82f1\u56fd\u30d5\u30e9\u30f3\u30b7\u30b9\u30af\u30ea\u30c3\u30af\u7814\u7a76\u6240\u30014. \u82f1\u56fd\u30d5\u30e9\u30f3\u30b7\u30b9\u30af\u30ea\u30c3\u30af\u7814\u7a76\u6240\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u90e8\u9580\u30015. \u82f1\u56fd\u30d5\u30e9\u30f3\u30b7\u30b9\u30af\u30ea\u30c3\u30af\u7814\u7a76\u6240\u5148\u9032\u5149\u5b66\u9855\u5fae\u93e1\u6280\u8853\u90e8\u9580\u30016.\u516c\u76ca\u8ca1\u56e3\u6cd5\u4eba \u304c\u3093\u7814\u7a76\u4f1a \u304c\u3093\u7814\u7a76\u6240\uff09<\/p>\n

\u63b2\u8f09\u65e5\u6642\uff08\u73fe\u5730\u6642\u9593\uff09\uff1a<\/strong>2022\u5e7412\u67086\u65e5\u5348\u524d\uff11\uff11\u6642\uff08\u7c73\u56fd\u6771\u90e8\u6a19\u6e96\u6642\uff09
\n\u63b2\u8f09\u65e5\u6642\uff08\u65e5\u672c\u6642\u9593\uff09\uff1a<\/strong>2022\u5e7412\u67087\u65e5\u5348\u524d\uff11\u6642
\nDOI<\/strong>\uff1a<\/strong>https:\/\/doi.org\/10.1016\/j.celrep.2022.111753<\/a>
\n\u63b2\u8f09URL\uff1ahttps:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(22)01636-9<\/a><\/p>\n

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\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a\u751f\u7269\u9032\u5316\u306b\u304a\u3051\u308b\u67d3\u8272\u4f53\u69cb\u9020\u306e\u5236\u5fa1\u6a5f\u69cb
\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u89d2\u4e95\u5eb7\u8ca2\uff08\u65e9\u7a32\u7530\u5927\u5b66\u9ad8\u7b49\u7814\u7a76\u6240\uff09<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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