{"id":84524,"date":"2022-10-21T11:00:03","date_gmt":"2022-10-21T02:00:03","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=84524"},"modified":"2022-10-21T11:53:18","modified_gmt":"2022-10-21T02:53:18","slug":"1%e5%88%86%e3%81%a7%e8%a3%85%e7%9d%80%e5%8f%af%e8%83%bd%e3%80%81%e8%85%b0%e3%81%a0%e3%81%91%e3%81%a7%e3%81%aa%e3%81%8f%e8%85%95%e3%81%ae%e8%b2%a0%e6%8b%85%e3%82%82%e8%bb%bd%e6%b8%9b%e3%81%99-2-3-4-59","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/84524","title":{"rendered":"\u7d30\u80de\u306e\u5206\u5316\u30fb\u904b\u547d\u6c7a\u5b9a\u56e0\u5b50\u3092\u767a\u898b"},"content":{"rendered":"<h1><strong>\u7d30\u80de\u306e\u6027\u5206\u5316\u3092\u963b\u6b62\u3059\u308b\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u767a\u898b<\/strong><\/h1>\n<p><strong>\u7d30\u80de\u5185\u3067\u6a5f\u80fd\u3092\u6301\u3064\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u63a2\u3057\u51fa\u3059\u65b9\u6cd5\u306e\u958b\u767a\u3068\u5b9f\u8df5<\/strong><\/p>\n<h2><strong>\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/h2>\n<ul>\n<li>\u7d30\u80de\u7814\u7a76\u306f\u5f93\u6765\u3001DNA\u3084\u9175\u7d20\u306a\u3069\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7740\u76ee\u3055\u308c\u3066\u304d\u305f\u304c\u3001\u8fd1\u5e74\u3001\u300c\u30b8\u30e3\u30f3\u30af\u300d\u3068\u3055\u308c\u3066\u3044\u305f\u4e00\u90e8\u306e\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u7d30\u80de\u306e\u4e2d\u3067\u91cd\u8981\u306a\u50cd\u304d\u3092\u62c5\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u672a\u77e5\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u52b9\u7387\u3088\u304f\u63a2\u3057\u51fa\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u308b\u3002<\/li>\n<li>\u6a5f\u80fd\u3092\u6709\u3059\u308b\u672a\u77e5\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u3001\u305d\u306e\u4e8c\u6b21\u69cb\u9020\u306b\u7740\u76ee\u3057\u3066\u751f\u7269\u60c5\u5831\u79d1\u5b66\u306e\u624b\u6cd5\u3092\u7528\u3044\u3066\u63a2\u3057\u51fa\u3059\u65b9\u6cd5\u3092\u958b\u767a\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u5206\u88c2\u9175\u6bcd<em>S.pombe<\/em>\u304c\u6709\u3059\u308b\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u4e2d\u304b\u3089\u3001\u6027\u5206\u5316\u3092\u963b\u6b62\u3059\u308b\u50cd\u304d\u3092\u6301\u3064\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u300cnc1669\u300d\u3092\u767a\u898b\u3057\u305f\u3002<\/li>\n<li>RNA\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u4e8c\u6b21\u69cb\u9020\u306b\u7740\u76ee\u3059\u308b\u3053\u3068\u306e\u6709\u52b9\u6027\u3092\u793a\u3057\u3001\u7d30\u80de\u306e\u5206\u5316\u30fb\u904b\u547d\u6c7a\u5b9a\u3092\u304a\u3053\u306a\u3046\u56e0\u5b50\u3068\u3057\u3066\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u591a\u304f\u95a2\u308f\u3063\u3066\u3044\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u3002<\/li>\n<\/ul>\n<h3><strong>\u6982\u8981<\/strong><\/h3>\n<p>\u65e9\u7a32\u7530\u5927\u5b66\u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1 \u535a\u58eb\u8ab2\u7a0b3\u5e74\u306e\u5927\u91ce \u60a0\uff08\u304a\u304a\u306e \u3086\u3046\uff09\u3001\u4fee\u58eb\u8ab2\u7a0b\uff08\u7814\u7a76\u5f53\u6642\uff09\u306e\u7247\u5c71 \u7814\u592a\uff08\u304b\u305f\u3084\u307e \u3051\u3093\u305f\uff09\u3001\u540c\u5927\u7406\u5de5\u5b66\u8853\u9662\u306e<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001261_ja.html\">\u6d5c\u7530 \u9053\u662d<\/a>\uff08\u306f\u307e\u3060 \u307f\u3061\u3042\u304d\uff09\u6559\u6388\u3001<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001201_ja.html\">\u4f50\u85e4 \u653f\u5145<\/a>\uff08\u3055\u3068\u3046 \u307e\u3055\u307f\u3064\uff09\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u751f\u7269\u60c5\u5831\u79d1\u5b66\u306e\u624b\u6cd5\u3092\u7528\u3044\u3066\u3001\u6a5f\u80fd\u3092\u6709\u3059\u308b\u672a\u77e5\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u63a2\u3057\u51fa\u3059\u65b9\u6cd5\u3092\u958b\u767a\u3057\u3001\u5206\u88c2\u9175\u6bcd\u7d30\u80de\u5185\u306b\u5b58\u5728\u3059\u308b\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u4e2d\u304b\u3089\u3001\u6027\u5206\u5316\u3092\u963b\u6b62\u3059\u308b\u50cd\u304d\u3092\u6301\u3064\u9577\u9396\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u3001Oxford University Press\u767a\u884c\u306e\u300e<a href=\"https:\/\/academic.oup.com\/nar\">Nucleic Acids Research<\/a>\u300f\uff08\u8ad6\u6587\u540d\uff1a<a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkac825\/6763385\">Structure-based screening for functional non-coding RNAs in fission yeast identifies a factor repressing untimely initiation of sexual differentiation<\/a>\uff09\u306b\u3066\u30012022\u5e7410\u670819\u65e5\uff08\u6c34\uff09\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h4><strong>\uff08\uff11\uff09\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/strong><\/h4>\n<p>\u4e00\u822c\u7684\u306b\u3001\u7d30\u80de\u306e\u6d3b\u52d5\u306b\u6b20\u304b\u305b\u306a\u3044\u5b9f\u884c\u90e8\u968a\u3067\u3042\u308b\u9175\u7d20\u306a\u3069\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u304b\u3089\u3067\u304d\u3066\u3044\u307e\u3059\u304c\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3082\u3068\u3082\u3068DNA\u306e\u5869\u57fa\u914d\u5217<sup>\u203b1<\/sup>\u304cRNA\uff08\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff09<sup>\u203b2<\/sup>\u306b\u8ee2\u5199\u3055\u308c\u3001\u305d\u306e\u5f8cRNA\u304b\u3089\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7ffb\u8a33\u3055\u308c\u3066\u3067\u304d\u305f\u3082\u306e\u3067\u3059\u3002\u3057\u304b\u3057\u3001RNA\u306e\u4e2d\u306b\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7ffb\u8a33\u3055\u308c\u306a\u3044\u3082\u306e\u304c\u3042\u308a\u3001\u3053\u308c\u3089\u306f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA<sup>\u203b3<\/sup>\u3068\u547c\u3070\u308c\u307e\u3059\u3002\u4e2d\u3067\u3082\u3001\u6bd4\u8f03\u7684\u9577\u3044\u5869\u57fa\u914d\u5217\u304b\u3089\u306a\u308b\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306f\u3001\u6a5f\u80fd\u3092\u6301\u305f\u306a\u3044\u3001\u3064\u307e\u308a\u300c\u30b8\u30e3\u30f3\u30af\u300d\u306a\u3082\u306e\u3060\u3068\u9577\u3044\u9593\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u8fd1\u5e74\u3001\u4e00\u90e8\u306e\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u7d30\u80de\u306e\u4e2d\u3067\u91cd\u8981\u306a\u50cd\u304d\u3092\u62c5\u3044\u3001\u307e\u305f\u3001\u304c\u3093\u306a\u3069\u306e\u75be\u60a3\u306b\u95a2\u308f\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u5f93\u6765\u306e\u3088\u3046\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u8abf\u3079\u308b\u306e\u307f\u3067\u306f\u306a\u304f\u3001\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u6a5f\u80fd\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306f\u9175\u6bcd\u7d30\u80de\u5185\u306b\u7d041,800\u7a2e\u985e\u3001\u30d2\u30c8\u7d30\u80de\u3067\u306f\u6570\u4e07\u7a2e\u985e\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u4e2d\u3067\u3001\u5177\u4f53\u7684\u306a\u6a5f\u80fd\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u305f\u3082\u306e\u306f\u308f\u305a\u304b1\uff05\u7a0b\u5ea6\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u83ab\u5927\u306a\u7a2e\u985e\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u4e2d\u304b\u3089\u3001\u7d30\u80de\u5185\u3067\u6a5f\u80fd\u3092\u6709\u3059\u308b\u672a\u77e5\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u52b9\u7387\u3088\u304f\u63a2\u3057\u51fa\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4><strong>\uff08\uff12\uff09\u4eca\u56de\u306e\u7814\u7a76\u3067\u65b0\u305f\u306b\u5b9f\u73fe\u3057\u3088\u3046\u3068\u3057\u305f\u3053\u3068\u3001\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3053\u3068<\/strong><\/h4>\n<p>RNA\u306fDNA\u3092\u92f3\u578b\u3068\u3057\u3066\u30011\u672c\u306e\u9396\u306e\u3088\u3046\u306a\u72b6\u614b\u3067\u8ee2\u5199\u3055\u308c\u307e\u3059\u304c\u3001\u305d\u306e\u5f8c\u3001RNA\u5206\u5b50\u5185\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u7acb\u4f53\u7684\u306a\u69cb\u9020\u3092\u4f5c\u308a\u307e\u3059\uff08\u56f31\uff09\u3002\u3053\u308c\u304c\u4e8c\u6b21\u69cb\u9020<sup>\u203b4<\/sup>\u3067\u3042\u308a\u3001RNA\u304c\u6a5f\u80fd\u3059\u308b\u4e0a\u3067\u306f\u3053\u306e\u4e8c\u6b21\u69cb\u9020\u306e\u304b\u305f\u3061\u304c\u975e\u5e38\u306b\u91cd\u8981\u3060\u3068\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u3042\u308b\u751f\u7269\u7a2e\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u50cd\u304d\u3092\u62c5\u3046\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306b\u3064\u3044\u3066\u306f\u3001\u7570\u306a\u308b\u751f\u7269\u7a2e\u306b\u304a\u3044\u3066\u3082\u3001\u3084\u306f\u308a\u540c\u3058\u3088\u3046\u306a\u914d\u5217\u3092\u6301\u3064\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u5b58\u5728\u3057\u3066\u3044\u3066\u3001\u304b\u3064\u3001\u305d\u308c\u3089\u306e\u4e8c\u6b21\u69cb\u9020\u3082\u307e\u305f\u985e\u4f3c\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u8003\u3048\u307e\u3057\u305f\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-84527\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato1.jpg\" alt=\"\" width=\"1782\" height=\"406\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato1.jpg 1782w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato1-610x139.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato1-768x175.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato1-1536x350.jpg 1536w\" sizes=\"auto, (max-width: 1782px) 100vw, 1782px\" \/><\/p>\n<h6>\u56f3\uff11\uff1a\uff12\u672c\u9396DNA\u304b\u30891\u672c\u9396\u306eRNA\u304c\u8ee2\u5199\u3055\u308c\u308b\u3002\u306a\u304b\u3067\u3082\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u306f\u7ffb\u8a33\u3055\u308c\u305a\u306b\u3001RNA\u306e\u5206\u5b50\u5185\u3067\u90e8\u5206\u7684\u306b\uff12\u672c\u9396\u3092\u4f5c\u308a\u306a\u304c\u3089\u6298\u308a\u305f\u305f\u307e\u308c\u308b\u3002\u3053\u306e\u4e8c\u6b21\u69cb\u9020\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u304c\u3001\u7d30\u80de\u5185\u3067\u4f55\u3089\u304b\u306e\u6a5f\u80fd\u3092\u679c\u305f\u3059\u305f\u3081\u306b\u91cd\u8981\u3067\u3042\u308b\u3002<\/h6>\n<p>\u305d\u3053\u3067\u3001\u5206\u88c2\u9175\u6bcd<em>S. pombe<\/em><sup>\u203b5<\/sup>\u304c\u6709\u3059\u308b\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA1,800\u7a2e\u985e\u306b\u3064\u3044\u3066\u3001\u8fd1\u7e01\u7a2e\u304c\u3082\u3064\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3068\u306e\u914d\u5217\u76f8\u540c\u6027\u3068\u4e8c\u6b21\u69cb\u9020\u306e\u985e\u4f3c\u6027\u3092\u6307\u6a19\u306b\u3057\u305f\u751f\u7269\u60c5\u5831\u79d1\u5b66\uff08\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\uff09<sup>\u203b6<\/sup>\u306e\u624b\u6cd5\u306b\u3088\u308b\u691c\u7d22\u624b\u6cd5\u3092\u78ba\u7acb\u3057\u3001\u65b0\u898f\u306e\u6a5f\u80fd\u6027\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u691c\u7d22\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u5206\u88c2\u9175\u6bcd\u3068\u305d\u306e\u8fd1\u7e01\u7a2e\u306b\u304a\u3044\u3066\u985e\u4f3c\u3057\u305f\u5869\u57fa\u914d\u5217\u304a\u3088\u3073\u4e8c\u6b21\u69cb\u9020\u3092\u6301\u3064\u9577\u9396\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u309271\u7a2e\u985e\u898b\u51fa\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u767a\u898b\u3057\u305f\u4e2d\u306e\u3072\u3068\u3064\u3067\u3042\u308b\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u300cnc1669\u300d\u306f\u3001\u7d30\u80de\u306e\u5468\u56f2\u306b\u6804\u990a\u6e90\u304c\u3042\u308b\u72b6\u614b\u3067\u306f\u6027\u5206\u5316\u306b\u5fc5\u9808\u306e\u8ee2\u5199\u56e0\u5b50\u300cSte11\u300d\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u50cd\u304d\u3092\u3082\u3064\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001nc1669\u306f\u6027\u5206\u5316\u3092\u6291\u3048\u308b\u6a5f\u80fd\u3092\u3082\u3064\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3067\u3042\u308b\u3068\u3044\u3048\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u8a73\u7d30\u3092\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n<p>\u751f\u7269\u60c5\u5831\u79d1\u5b66\u3092\u7528\u3044\u3066\u65b0\u898f\u306e\u6a5f\u80fd\u6027\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u898b\u3064\u3051\u51fa\u3059\u305f\u3081\u306b\u672c\u7814\u7a76\u3067\u306f\u3001\u5206\u88c2\u9175\u6bcd\u306e\u7d30\u80de\u5185\u3067\u91cd\u8981\u306a\u50cd\u304d\u3092\u62c5\u3046RNA\u306f\u3001\u9032\u5316\u5206\u985e\u5b66\u7684\u306b\u8fd1\u7e01\u7a2e\u306e\u9175\u6bcd\u306b\u304a\u3044\u3066\u3082\u305d\u306e\u6a5f\u80fd\u304c\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b\u3067\u3042\u308d\u3046\u3068\u60f3\u5b9a\u3057\u307e\u3057\u305f\u3002\u3059\u306a\u308f\u3061\u3001\u305d\u306e\u3088\u3046\u306a\u91cd\u8981\u306a\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306f\u3001\u304a\u305d\u3089\u304f\u4e21\u751f\u7269\u7a2e\u3067\u5869\u57fa\u914d\u5217\u304c\u3042\u307e\u308a\u5909\u5316\u3057\u3066\u3044\u306a\u3044\u306f\u305a\u3067\u3059\u3002\u307e\u305f\u3001RNA\u304c\u6a5f\u80fd\u3092\u767a\u63ee\u3059\u308b\u969b\u306f\u8907\u96d1\u306b\u6298\u308a\u305f\u305f\u307e\u308c\u3066\u300c\u4e8c\u6b21\u69cb\u9020\u300d\u3092\u53d6\u308b\u3053\u3068\u304c\u5927\u4e8b\u3067\u3059\u304b\u3089\uff08\u56f31\uff09\u3001\u4e21\u751f\u7269\u7a2e\u306e\u9593\u3067\u305d\u306e\u6a5f\u80fd\u304c\u7dad\u6301\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u4e8c\u6b21\u69cb\u9020\u3082\u307e\u305f\u985e\u4f3c\u3057\u3066\u3044\u308b\u306f\u305a\u3060\u3068\u7740\u60f3\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u3088\u3046\u306a\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u63a2\u3057\u51fa\u3059\u305f\u3081\u306b\u3001\u5206\u88c2\u9175\u6bcd\u30b2\u30ce\u30e0\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u767b\u9332\u3055\u308c\u305f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u7d041,800\u7a2e\u985e\u3068\u8fd1\u7e01\u7a2e\u30b2\u30ce\u30e0\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u767b\u9332\u3055\u308c\u305f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3068\u3092\u6bd4\u3079\u3066\u3001\u5869\u57fa\u914d\u5217\u3068\u4e8c\u6b21\u69cb\u9020\u304c\u985e\u4f3c\u3057\u3066\u3044\u308b\u3082\u306e\u3092\u691c\u7d22\u3057\u3001\u9078\u51fa\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306a\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u89e3\u6790\u3092\u304a\u3053\u306a\u3063\u305f\u7d50\u679c\u3001\u5206\u88c2\u9175\u6bcd\u3068\u305d\u306e\u8fd1\u7e01\u7a2e\u306b\u304a\u3044\u3066\u985e\u4f3c\u3057\u305f\u5869\u57fa\u914d\u5217\u304a\u3088\u3073\u4e8c\u6b21\u69cb\u9020\u3092\u6301\u3064\u9577\u9396\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c71\u7a2e\u985e\u898b\u3064\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u4e2d\u306b\u3001\u7d30\u80de\u306e\u4e2d\u3067\u4f55\u3089\u304b\u306e\u6a5f\u80fd\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3082\u306e\u304c\u3042\u308b\u3053\u3068\u304c\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002\u6b21\u306b\u3001\u3053\u308c\u3089\u306e\u6a5f\u80fd\u3092\u5931\u308f\u305b\u305f\u7d30\u80de\u30921\u7a2e\u985e\u305a\u3064\u4f5c\u88fd\u3057\u3001\u7d30\u80de\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u73fe\u308c\u308b\u304b\u3092\u89b3\u5bdf\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001nc1669\u3068\u3044\u3046\u540d\u306e\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u6b20\u5931\u3055\u305b\u308b\u3068\u3001\u5206\u88c2\u9175\u6bcd\u306e\u6027\u5206\u5316\u304c\u7570\u5e38\u306b\u9032\u884c\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u3053\u3067\u3044\u3046\u6027\u5206\u5316\u306f\u3001\u7d30\u80de\u306e\u5206\u5316\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u3072\u305f\u3059\u3089\u6027\u5225\u306b\u3088\u3089\u306a\u3044\u4f53\u7d30\u80de\u5206\u88c2\uff08\u7121\u6027\u751f\u6b96<sup>\u203b7<\/sup>\uff09\u3092\u7e70\u308a\u8fd4\u3057\u3066\u3044\u305f\u7d30\u80de\u304c\u3001\u3042\u308b\u6642\u305d\u306e\u4f53\u7d30\u80de\u5206\u88c2\u3092\u3084\u3081\u3066\u3001\u6027\u5225\u3092\u5229\u7528\u3057\u305f\u5206\u88c2\u3059\u306a\u308f\u3061\u6e1b\u6570\u5206\u88c2\uff08\u6709\u6027\u751f\u6b96<sup>\u203b8<\/sup>\uff09\u3078\u3068\u79fb\u884c\u3059\u308b\u3053\u3068\u3092\u6027\u5206\u5316\u3068\u547c\u3073\u307e\u3059\uff08\u56f32\uff09\u3002\u7d30\u80de\u304c\u81ea\u8eab\u306e\u3053\u308c\u304b\u3089\u306e\u904b\u547d\u3092\u6c7a\u3081\u308b\u300c\u904b\u547d\u6c7a\u5b9a\u300d\u30a4\u30d9\u30f3\u30c8\u306e\u3072\u3068\u3064\u3068\u3044\u3048\u307e\u3059\u3002\u672c\u7814\u7a76\u304c\u767a\u898b\u3057\u305f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306enc1669\u306f\u3053\u306e\u904b\u547d\u6c7a\u5b9a\u306b\u95a2\u308f\u308b\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<p>\u5206\u88c2\u9175\u6bcd\u306e\u6027\u5206\u5316\u306f\u3001\u5468\u56f2\u306e\u74b0\u5883\u4e2d\u306b\u542b\u307e\u308c\u308b\u6804\u990a\u306e\u6709\u7121\u3068\u5bc6\u63a5\u306b\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u74b0\u5883\u4e2d\uff08\u4f8b\u3048\u3070\u57f9\u5730\uff09\u306b\u6804\u990a\u304c\u8c4a\u5bcc\u306a\u5834\u5408\u306f\u4f53\u7d30\u80de\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3057\u307e\u3059\uff08\u56f32\uff09\u3002\u3059\u306a\u308f\u3061\u3001\u6804\u990a\u304c\u3042\u308b\u6642\u306f\u305d\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u5b58\u5206\u306b\u5229\u7528\u3057\u3066\u7121\u6027\u7684\u306b\u7d30\u80de\u3092\u5897\u6b96\u3055\u305b\u308b\u3053\u3068\u304c\u7a2e\u306e\u7e41\u6804\u306b\u6700\u9069\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u74b0\u5883\u4e2d\u306e\u6804\u990a\u6e90\u3001\u7279\u306b\u7a92\u7d20\u6e90\u304c\u67af\u6e07\u3059\u308b\u3068\u3001\u7d30\u80de\u306f\u305d\u306e\u3053\u3068\u3092\u8a8d\u8b58\u3057\u3066\u4f53\u7d30\u80de\u5206\u88c2\u3092\u505c\u6b62\u3057\u3001\u6027\u5206\u5316\u3092\u59cb\u3081\u307e\u3059\uff08\u56f32\uff09\u3002\u6804\u990a\u304c\u306a\u3044\u6642\u306b\u306f\u7d30\u80de\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3059\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u4e0d\u8db3\u3059\u308b\u306e\u3067\u3001\u7dca\u6025\u7684\u306b\u6027\u5206\u5316\u3057\u3066\u6700\u5c0f\u9650\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3067\u6e1b\u6570\u5206\u88c2\u3092\u304a\u3053\u306a\u3044\u3001\u80de\u5b50\uff08\u52d5\u690d\u7269\u306b\u304a\u3051\u308b\u914d\u5076\u5b50\uff1d\u7cbe\u5b50\u3084\u5375\u5b50\u306b\u76f8\u5f53\u3059\u308b\u7d30\u80de\uff09\u3092\u4f5c\u308a\u307e\u3059\u3002\u80de\u5b50\u306f\u74b0\u5883\u4e2d\u306b\u6804\u990a\u304c\u306a\u304f\u3066\u3082\u9577\u671f\u4f11\u7720\u3057\u3066\u8010\u3048\u307e\u3059\u304c\u3001\u74b0\u5883\u4e2d\u306b\u307e\u305f\u6804\u990a\u304c\u5897\u3048\u308b\u3068\u3000\u4f11\u7720\u304b\u3089\u306e\u76ee\u899a\u3081\u3092\u958b\u59cb\u3057\u307e\u3059\uff08\u53c2\u7167\uff1a<a href=\"https:\/\/www.waseda.jp\/top\/news\/68589\">\u4ee5\u524d\u306e\u7814\u7a76\u6210\u679c<\/a>\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-84528\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato2.jpg\" alt=\"\" width=\"1804\" height=\"529\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato2.jpg 1804w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato2-610x179.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato2-768x225.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato2-1536x450.jpg 1536w\" sizes=\"auto, (max-width: 1804px) 100vw, 1804px\" \/><\/p>\n<h6>\u56f32\uff1a\u5206\u88c2\u9175\u6bcd\u306f\u74b0\u5883\u306e\u6804\u990a\u6e90\uff08\u7a92\u7d20\u6e90\uff09\u304c\u67af\u6e07\u3059\u308b\u3068\u4f53\u7d30\u80de\u5206\u88c2\u3092\u505c\u6b62\u3057\u3001\u6027\u5206\u5316\u3092\u958b\u59cb\u3059\u308b\u3002\u3059\u306a\u308f\u3061\u3001\u7570\u306a\u308b2\u3064\u306e\u6027\u5225\u306e\u7d30\u80de\u304c\u300c\u63a5\u5408\u300d\u3057\u305f\u5f8c\u306b\u300c\u6e1b\u6570\u5206\u88c2\u300d\u3092\u304a\u3053\u306a\u3044\u3001\u914d\u5076\u5b50\u3067\u3042\u308b\u80de\u5b50\u3092\u5f62\u6210\u3059\u308b\u3002<\/h6>\n<p>\u3064\u307e\u308a\u3001\u7d30\u80de\u306f\u6804\u990a\u6e90\u304c\u8c4a\u5bcc\u306a\u6642\u306f\u305d\u308c\u3092\u611f\u77e5\u3057\u3066\u4f53\u7d30\u80de\u5206\u88c2\u3092\u304a\u3053\u306a\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u3068\u304d\u306f\u6027\u5206\u5316\u3092\u3057\u306a\u3044\u3088\u3046\u306a\u6291\u5236\u6a5f\u69cb\u304c\u50cd\u3044\u3066\u3044\u308b\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u306b\u304a\u3044\u3066\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u3092\u99c6\u4f7f\u3057\u3066\u767a\u898b\u3057\u305f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u300cnc1669\u300d\u3092\u4eba\u5de5\u7684\u306b\u6b20\u5931\u3055\u305b\u305f\u5909\u7570\u7d30\u80de\u3092\u4f5c\u88fd\u3057\u3066\u89b3\u5bdf\u3057\u305f\u3068\u3053\u308d\u3001\u7a92\u7d20\u6e90\u304c\u3042\u308b\u74b0\u5883\u4e0b\u3067\u3082\u4e00\u90e8\u306e\u7d30\u80de\u304c\u6027\u5206\u5316\u3092\u958b\u59cb\u3057\u307e\u3057\u305f\uff08\u56f33\u5de6\uff09\u3002\u3055\u3089\u306b\u3001\u6027\u5206\u5316\u3092\u958b\u59cb\u3059\u308b\u305f\u3081\u306b\u5fc5\u9808\u306e\u8ee2\u5199\u56e0\u5b50\uff08\u8ee2\u5199\u6d3b\u6027\u5316\u56e0\u5b50\uff09<sup>\u203b9<\/sup>\u3092\u6307\u5b9a\uff08\u30b3\u30fc\u30c9\uff09\u3059\u308b<em>ste11<\/em>\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304cnc1669\u6b20\u5931\u7d30\u80de\u3067\u306f\u7570\u5e38\u306b\u5897\u52a0\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u7a81\u304d\u6b62\u3081\u307e\u3057\u305f\uff08\u56f33\u53f3\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-84529\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato3.jpg\" alt=\"\" width=\"1588\" height=\"559\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato3.jpg 1588w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato3-610x215.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato3-768x270.jpg 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato3-1536x541.jpg 1536w\" sizes=\"auto, (max-width: 1588px) 100vw, 1588px\" \/><\/p>\n<h6>\u56f3\uff13\uff1anc1669\u6b20\u5931\u7d30\u80de\u3067\u306f\u3001\u7a92\u7d20\u6e90\u304c\u3042\u308b\u74b0\u5883\u3067\u3082\u7d30\u80de\u306e\u63a5\u5408\u304c\u9ad8\u983b\u5ea6\u3067\u307f\u3089\u308c\u305f\uff08\u5de6\uff09\u3002\u3053\u308c\u306f\u3001\u6027\u5206\u5316\u306b\u5fc5\u9808\u306e\u5f79\u5272\u3092\u62c5\u3046\u8ee2\u5199\u56e0\u5b50Ste11\u306e\u767a\u73fe\u304cnc1669\u6b20\u5931\u7d30\u80de\u3067\u5897\u52a0\u3057\u305f\u305f\u3081\u3060\u3068\u8003\u3048\u3089\u308c\u308b\uff08\u53f3\uff09\u3002<\/h6>\n<p>\u7a92\u7d20\u6e90\u304c\u3042\u308a\u3001\u672c\u6765\u3067\u3042\u308c\u3070\u6027\u5206\u5316\u3092\u304a\u3053\u306a\u3046\u5834\u9762\u3067\u306f\u306a\u3044\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001nc1669\u6b20\u5931\u7d30\u80de\u3067\u306f\u8ee2\u5199\u56e0\u5b50Ste11\u306e\u7570\u5e38\u306a\u5897\u52a0\u304c\u8d77\u304d\u3066\u3057\u307e\u3044\u3001\u3053\u308c\u304c\u6027\u5206\u5316\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u5165\u308c\u3066\u3057\u307e\u3063\u305f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\uff08\u56f34\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-84530\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato4.jpg\" alt=\"\" width=\"686\" height=\"271\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato4.jpg 1254w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato4-610x241.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2022\/10\/graph_sato4-768x303.jpg 768w\" sizes=\"auto, (max-width: 686px) 100vw, 686px\" \/><\/p>\n<h6>\u56f3\uff14\uff1a\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3067\u3042\u308bnc1669\u306f\u3001\u7a92\u7d20\u6e90\u304c\u3042\u308b\u6642\u306b\u3001\u8ee2\u5199\u56e0\u5b50Ste11\u306e\u767a\u73fe\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u5206\u88c2\u9175\u6bcd\u304c\u6027\u5206\u5316\u3057\u306a\u3044\u3088\u3046\u5236\u5fa1\u3057\u3066\u3044\u308b<\/h6>\n<h4><strong>\uff08\uff13\uff09<\/strong><strong>\u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c\u3084\u793e\u4f1a\u7684\u5f71\u97ff<\/strong><\/h4>\n<p>\u3053\u308c\u307e\u3067\u306b\u3001\u6a5f\u80fd\u3092\u6301\u3064\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u6570\u591a\u304f\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e8c\u6b21\u69cb\u9020\u306b\u7740\u76ee\u3057\u305f\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u307b\u3068\u3093\u3069\u4f8b\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u672c\u7814\u7a76\u3067\u306f\u5b9f\u969b\u306b\u305d\u308c\u3092\u884c\u3044\u3001nc1669\u306e\u91cd\u8981\u306a\u6a5f\u80fd\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002RNA\u7814\u7a76\u306b\u304a\u3044\u3066\u4e8c\u6b21\u69cb\u9020\u306b\u7740\u76ee\u3059\u308b\u3053\u3068\u306e\u6709\u52b9\u6027\u304c\u3088\u308a\u660e\u78ba\u306b\u306a\u3063\u305f\u3068\u3044\u3048\u307e\u3059\u3002\u30d2\u30c8\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308bRNA\u306b\u3064\u3044\u3066\u3001\u672c\u7814\u7a76\u3067\u958b\u767a\u3057\u305f\u624b\u6cd5\u3067\u8fd1\u7e01\u7a2e\u3068\u985e\u4f3c\u3057\u3066\u3044\u308b\u4e8c\u6b21\u69cb\u9020\u3092\u63a2\u3057\u51fa\u305b\u308c\u3070\u3001\u305d\u306e\u4e8c\u6b21\u69cb\u9020\u3092\u6a19\u7684\u3068\u3057\u305f\u85ac\u5264\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u3001\u5206\u88c2\u9175\u6bcd\u306e\u6027\u5206\u5316\u3092\u5236\u5fa1\u3059\u308b\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u767a\u898b\u3057\u305f\u6210\u679c\u304b\u3089\u3001\u7d30\u80de\u306e\u5206\u5316\u30fb\u904b\u547d\u6c7a\u5b9a\u3092\u304a\u3053\u306a\u3046\u56e0\u5b50\u304c\u5fc5\u305a\u3057\u3082\u5f93\u6765\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3060\u3051\u3068\u306f\u9650\u3089\u305a\u3001\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u591a\u304f\u95a2\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u5f90\u3005\u306b\u660e\u3089\u304b\u306b\u306a\u308b\u3068\u8003\u3048\u307e\u3059\u3002\u904b\u547d\u6c7a\u5b9a\u306e\u8003\u3048\u65b9\u306f\u5f93\u6765\u3068\u306f\u5927\u304d\u304f\u5909\u308f\u308b\u3060\u308d\u3046\u3068\u6349\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4><strong>\uff08\uff14\uff09<\/strong><strong>\u4eca\u5f8c\u306e\u8ab2\u984c<\/strong><\/h4>\n<p>\u4eca\u56de\u306e\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u691c\u7d22\u3067\u5f97\u3089\u308c\u305f\u6a5f\u80fd\u6027\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u5019\u88dc\u306e\u4e2d\u306b\u306f\u3001\u672a\u3060\u305d\u306e\u6a5f\u80fd\u3092\u8abf\u3079\u3089\u308c\u3066\u3044\u306a\u3044\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA nc1669\u304c\u5177\u4f53\u7684\u306b\u3069\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3067<em>ste11<\/em>\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u306e\u304b\u3082\u8abf\u3079\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u3092\u901a\u3057\u3066\u3001\u7d30\u80de\u5206\u5316\u306e\u904b\u547d\u6c7a\u5b9a\u304c\u3069\u306e\u3088\u3046\u306b\u306a\u3055\u308c\u308b\u306e\u304b\u3001\u7d30\u80de\u5185\u306e\u771f\u5b9f\u3092\u63cf\u304d\u51fa\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<h4><strong>\uff08\uff15\uff09<\/strong><strong>\u7814\u7a76\u8005\u304b\u3089\u306e\u30b3\u30e1\u30f3\u30c8<\/strong><\/h4>\n<p>\u5206\u88c2\u9175\u6bcd\u306b\u304a\u3051\u308b\u4e8c\u6b21\u69cb\u9020\u306b\u7740\u76ee\u3057\u305fRNA\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u4e16\u754c\u521d\u306e\u8a66\u307f\u3067\u3057\u305f\u304c\u3001nc1669\u306e\u91cd\u8981\u306a\u6a5f\u80fd\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u975e\u5e38\u306b\u610f\u7fa9\u6df1\u3044\u7814\u7a76\u3067\u3042\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u30d2\u30c8\u3067\u306f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u75be\u60a3\u3068\u95a2\u9023\u3059\u308b\u5831\u544a\u4f8b\u304c\u76f8\u6b21\u3044\u3067\u304a\u308a\u3001\u4eca\u5f8c\u3001\u672c\u624b\u6cd5\u3092\u5fdc\u7528\u3057\u305f\u30d2\u30c8\u306e\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u691c\u7d22\u3092\u5b9f\u65bd\u3057\u305f\u3044\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n<h4><strong>\uff08\uff16\uff09\u7528\u8a9e\u89e3\u8aac<\/strong><\/h4>\n<p><strong>\u203b1 \u5869\u57fa\u914d\u5217<br \/>\n<\/strong>DNA\u3084RNA\u3068\u3044\u3063\u305f\u6838\u9178\u304c\u7d50\u5408\u3059\u308b\u9806\u756a\u3092\u3001\u5869\u57fa\u306b\u3088\u3063\u3066\u8868\u3057\u305f\u60c5\u5831\u306e\u3053\u3068\u3002DNA\u3067\u3042\u308c\u3070\u30a2\u30c7\u30cb\u30f3(A)\u3001\u30c1\u30df\u30f3(T)\u3001\u30b0\u30a2\u30cb\u30f3(G)\u3001\u30b7\u30c8\u30b7\u30f3(C)\u306e4\u7a2e\u985e\u306e\u5869\u57fa\u304c\u5b58\u5728\u3059\u308b\u306e\u3067\u3001DNA\u306e\u5869\u57fa\u914d\u5217\u306fA\u3001T\u3001G\u3001C\u306e\u4e26\u3073\u306b\u3088\u3063\u3066\u8868\u3055\u308c\u308b\u3002<\/p>\n<p><strong>\u203b2 RNA<br \/>\n<\/strong>\u6838\u9178\u306e\u3072\u3068\u3064\u3002RNA\u3092\u69cb\u6210\u3059\u308b\u5869\u57fa\u306f\u3001\u30a2\u30c7\u30cb\u30f3(A)\u3001\u30a6\u30e9\u30b7\u30eb(U)\u3001\u30b0\u30a2\u30cb\u30f3(G)\u3001\u30b7\u30c8\u30b7\u30f3(C)\u306e4\u7a2e\u985e\u3067\u3042\u308b\u3002DNA\u304b\u3089\u8ee2\u5199\u3055\u308c\u3066\u5408\u6210\u3055\u308c\u308b\u3002mRNA\uff08\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff09\u3084\u904b\u642cRNA\uff08\u30c8\u30e9\u30f3\u30b9\u30d5\u30a1\u30fcRNA\uff09\u306a\u3069\u306f\u305d\u306e\u4e00\u7a2e\u3067\u3042\u308b\u3002<\/p>\n<p><strong>\u203b3 \u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA<br \/>\n<\/strong>DNA\u304b\u3089\u8ee2\u5199\u3055\u308c\u305fRNA\u306e\u3046\u3061\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7ffb\u8a33\u3055\u308c\u306a\u3044\u3082\u306e\u3002\u4e00\u822c\u7684\u306b\u3001200\u5869\u57fa\u4ee5\u4e0b\u306e\u3082\u306e\u306f\u77ed\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3001\u305d\u308c\u3088\u308a\u3082\u9577\u3044\u3082\u306e\u306f\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3068\u547c\u3070\u308c\u308b\u3002\u77ed\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306b\u306f\u904b\u642cRNA\u3084\u30ea\u30dc\u30bd\u30fc\u30e0RNA\u306a\u3069\u304c\u3042\u308a\u3001\u7d30\u80de\u5185\u3067\u91cd\u8981\u306a\u6a5f\u80fd\u3092\u679c\u305f\u3059\u3002\u4e00\u65b9\u3067\u3001\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3067\u6a5f\u80fd\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3082\u306e\u306f\u3054\u304f\u4e00\u90e8\u3067\u3042\u308b\u3002<\/p>\n<p><strong>\u203b4 \uff08RNA\u306e\uff09\u4e8c\u6b21\u69cb\u9020<br \/>\n<\/strong>RNA\u304c\u4f5c\u308b\u7acb\u4f53\u7684\u306a\u69cb\u9020\u3002\uff11\u5206\u5b50\u306eRNA\u306e\u5185\u90e8\u3067\u5869\u57fa\u3069\u3046\u3057\u304c\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u5f62\u6210\u3055\u308c\u308b\u3002\u4e3b\u306b\u3001\u30a2\u30c7\u30cb\u30f3(A)\u3068\u30a6\u30e9\u30b7\u30eb(U)\u3001\u30b0\u30a2\u30cb\u30f3(G)\u3068\u30b7\u30c8\u30b7\u30f3(C)\u304c\u305d\u308c\u305e\u308c\u6c34\u7d20\u7d50\u5408\u306b\u3088\u3063\u3066\u9023\u7d50\u3057\u3066\u3001\u5869\u57fa\u5bfe\u3068\u547c\u3070\u308c\u308bRNA\uff12\u672c\u9396\u306e\u90e8\u5206\u3092\u4f5c\u308b\u3002\u4e8c\u6b21\u69cb\u9020\u306fRNA\u306e\u5869\u57fa\u914d\u5217\u3084\u9577\u3055\u306b\u3088\u3063\u3066\u3055\u307e\u3056\u307e\u306a\u5f62\u30fb\u5927\u304d\u3055\u3068\u306a\u308a\u3001\u305d\u306e\u69cb\u9020\u304c\u3001\u7d30\u80de\u5185\u3067RNA\u304c\u6a5f\u80fd\u3059\u308b\u305f\u3081\u306b\u5fc5\u9808\u3067\u3042\u308b<\/p>\n<p><strong>\u203b5 \u5206\u88c2\u9175\u6bcd<em>S. pombe<\/em><br \/>\n<\/strong>\u771f\u6838\u751f\u7269\u3067\u3042\u308b\u771f\u83cc\u306e\u4e00\u7a2e\u3002\u907a\u4f1d\u5b50\u6539\u5909\u64cd\u4f5c\u304c\u7c21\u4fbf\u306a\u3053\u3068\u3001\u30d2\u30c8\u3068\u306e\u9593\u3067\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u5171\u901a\u3057\u3066\u3044\u308b\u3053\u3068\u306a\u3069\u304b\u3089\u3001\u7d30\u80de\u5185\u306e\u5206\u5b50\u30b7\u30b9\u30c6\u30e0\u3092\u7814\u7a76\u3059\u308b\u305f\u3081\u306e\u30e2\u30c7\u30eb\u751f\u7269\u3068\u3057\u3066\u6d3b\u7528\u3055\u308c\u3066\u3044\u308b\u3002\u3002<\/p>\n<p><strong>\u203b6 \u751f\u7269\u60c5\u5831\u79d1\u5b66\uff08\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\uff09<br \/>\n<\/strong>\u751f\u7269\u5b66\u3068\u60c5\u5831\u79d1\u5b66\u3092\u878d\u5408\u3055\u305b\u305f\u5b66\u554f\u3002DNA\u3001RNA\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306a\u3069\u306e\u751f\u7269\u5b66\u7684\u60c5\u5831\u3092\u3001\u60c5\u5831\u79d1\u5b66\u3084\u7d71\u8a08\u5b66\u306e\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u3088\u3063\u3066\u89e3\u6790\u3059\u308b\u3002<\/p>\n<p><strong>\u203b7 \u7121\u6027\u751f\u6b96<br \/>\n<\/strong>\u3072\u3068\u3064\u306e\u500b\u4f53\u306e\u4f53\u304b\u3089\u4e00\u90e8\u304c\u5206\u96e2\u3057\u3001\u65b0\u305f\u306a\u500b\u4f53\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u3002\u65b0\u3057\u304f\u751f\u307e\u308c\u305f\u500b\u4f53\u306f\u3001\u5143\u306e\u500b\u4f53\u3068\u5168\u304f\u540c\u3058\u907a\u4f1d\u60c5\u5831\u3092\u6301\u3064\u3002\u6027\u5225\u3092\u5229\u7528\u3057\u306a\u3044\u751f\u6b96\u306e\u5f62\u614b\u3068\u3044\u3048\u308b\u3002<\/p>\n<p><strong>\u203b8 \u6709\u6027\u751f\u6b96<\/strong><strong><br \/>\n<\/strong>\u6027\u306e\u7570\u306a\u308b2\u3064\u306e\u500b\u4f53\u306e\u9593\u3067\u907a\u4f1d\u5b50\u306e\u3084\u308a\u53d6\u308a\u3092\u884c\u3044\u3001\u65b0\u305f\u306a\u500b\u4f53\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u3002\u65b0\u3057\u304f\u751f\u307e\u308c\u305f\u500b\u4f53\u306f\u4e21\u89aa\u3068\u7570\u306a\u308b\u907a\u4f1d\u60c5\u5831\u3092\u6301\u3064\u3002\u907a\u4f1d\u5b50\u3092\u30df\u30c3\u30af\u30b9\u3057\u3066\u5206\u914d\u3059\u308b\u3053\u3068\u3067\u591a\u69d8\u306a\u500b\u4f53\u304c\u3046\u307e\u308c\u308b\u3053\u3068\u304c\u3001\u6027\u5225\u3092\u5229\u7528\u3057\u305f\u751f\u6b96\u306e\u6700\u5927\u306e\u30e1\u30ea\u30c3\u30c8\u3067\u3042\u308b\u3002<\/p>\n<p><strong>\u203b9 \u8ee2\u5199\u56e0\u5b50<br \/>\n<\/strong>DNA\u306b\u7d50\u5408\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u7d50\u5408\u3057\u305fDNA\u90e8\u5206\u304b\u3089\u306eRNA\u306e\u8ee2\u5199\u3092\u4fc3\u3059\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u6d3b\u6027\u5316\u3059\u308b\u50cd\u304d\u3092\u3082\u3064\u3002<\/p>\n<h4><strong>\uff08\uff17\uff09\u8ad6\u6587\u60c5\u5831<\/strong><\/h4>\n<p><strong>\u96d1\u8a8c\u540d\uff1a<\/strong>Nucleic Acids Research<br \/>\n<strong>\u8ad6\u6587\u540d\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkac825\/6763385\">Structure-based screening for functional non-coding RNAs in fission yeast identifies a factor repressing untimely initiation of sexual differentiation<\/a><br \/>\n<strong>\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a<\/strong>\u5927\u91ce\u60a0<sup>1<\/sup>\u3001\u7247\u5c71\u7814\u592a<sup>1,3<\/sup>\u3001\u5927\u6cbc\u53cb\u6a39<sup>1<\/sup>\u3001\u4e45\u4fdd\u9855\u767b<sup>2,3<\/sup>\u3001\u9732\u5d0e\u96bc<sup>1,3<\/sup>\u3001\u6d5c\u7530\u9053\u662d<sup>2,3,4<\/sup>\u3001\u4f50\u85e4\u653f\u5145<sup>1,4,5<br \/>\n<\/sup>1. <a href=\"https:\/\/www.ase.sci.waseda.ac.jp\/\">\u65e9\u7a32\u7530\u5927\u5b66 \u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1<\/a> \u751f\u547d\u533b\u79d1\u5b66\u5c02\u653b<br \/>\n2. <a href=\"https:\/\/www.ase.sci.waseda.ac.jp\/\">\u65e9\u7a32\u7530\u5927\u5b66 \u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1<\/a> \u96fb\u6c17\u30fb\u60c5\u5831\u751f\u547d\u5c02\u653b<br \/>\n3. <a href=\"https:\/\/unit.aist.go.jp\/cbbd-oil\/\">\u7523\u7dcf\u7814\u30fb\u65e9\u5927 \u751f\u4f53\u30b7\u30b9\u30c6\u30e0\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u30aa\u30fc\u30d7\u30f3\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u30e9\u30dc\u30e9\u30c8\u30ea<\/a><br \/>\n4. <a href=\"https:\/\/www.waseda.jp\/inst\/cro\/institutes-list\/institute-for-medical-oriented-structural-biology\/\">\u65e9\u7a32\u7530\u5927\u5b66 \u69cb\u9020\u751f\u7269\u30fb\u5275\u85ac\u7814\u7a76\u6240<\/a><br \/>\n5. <a href=\"http:\/\/www.ohshima.biomed.sci.waseda.ac.jp\/iar\/index.html\">\u65e9\u7a32\u7530\u5927\u5b66 \u5148\u9032\u751f\u547d\u52d5\u614b\u7814\u7a76\u6240<\/a><br \/>\n<strong>\u63b2\u8f09\u65e5\u6642\uff1a<\/strong>2022\u5e7410\u670819\u65e5\uff08\u6c34\uff09<br \/>\n<strong>\u63b2\u8f09URL\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkac825\/6763385\">https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkac825\/6763385<\/a><br \/>\n<strong>DOI\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkac825\/6763385\">10.1093\/nar\/gkac825<\/a><\/p>\n<h4>\uff08\uff18\uff09\u7814\u7a76\u52a9\u6210<\/h4>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u7814\u8cbb\u3000\u65b0\u5b66\u8853\u9818\u57df\u7814\u7a76\u300c\u907a\u4f1d\u5b50\u5236\u5fa1\u306e\u57fa\u76e4\u3068\u306a\u308b\u30af\u30ed\u30de\u30c1\u30f3\u30dd\u30c6\u30f3\u30b7\u30e3\u30eb\u300d<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a\u7d30\u80de\u306e\u76ee\u899a\u3081\u3092\u5f15\u304d\u8d77\u3053\u3059\u907a\u4f1d\u5b50\u5236\u5fa1\u306e\u57fa\u76e4\u3068\u306a\u308b\u30af\u30ed\u30de\u30c1\u30f3\u306e\u6642\u9593\u7684\u5909\u5316<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u4f50\u85e4 \u653f\u5145\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7d30\u80de\u306e\u6027\u5206\u5316\u3092\u963b\u6b62\u3059\u308b\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u767a\u898b \u7d30\u80de\u5185\u3067\u6a5f\u80fd\u3092\u6301\u3064\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u3092\u63a2\u3057\u51fa\u3059\u65b9\u6cd5\u306e\u958b\u767a\u3068\u5b9f\u8df5 \u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8 \u7d30\u80de\u7814\u7a76\u306f\u5f93\u6765\u3001DNA\u3084\u9175\u7d20\u306a\u3069\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7740\u76ee\u3055\u308c\u3066\u304d\u305f\u304c\u3001\u8fd1\u5e74\u3001\u300c\u30b8\u30e3\u30f3\u30af [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":84531,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[357,5],"class_list":["post-84524","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/84524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=84524"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/84524\/revisions"}],"predecessor-version":[{"id":84536,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/84524\/revisions\/84536"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/84531"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=84524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=84524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=84524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}