{"id":73853,"date":"2021-07-15T14:10:58","date_gmt":"2021-07-15T05:10:58","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=73853"},"modified":"2021-07-15T14:10:07","modified_gmt":"2021-07-15T05:10:07","slug":"1%e5%88%86%e3%81%a7%e8%a3%85%e7%9d%80%e5%8f%af%e8%83%bd%e3%80%81%e8%85%b0%e3%81%a0%e3%81%91%e3%81%a7%e3%81%aa%e3%81%8f%e8%85%95%e3%81%ae%e8%b2%a0%e6%8b%85%e3%82%82%e8%bb%bd%e6%b8%9b%e3%81%99-2-3-4-40","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/73853","title":{"rendered":"\u6642\u9593\u306b\u4f34\u3046\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u5316\u3092\u63a8\u5b9a"},"content":{"rendered":"<h2>\u6642\u9593\u7d4c\u904e\u306b\u4f34\u3046\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u5316\u3092\u63a8\u5b9a\u3059\u308b\u624b\u6cd5\u3092\u958b\u767a<\/h2>\n<h3>\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/h3>\n<ul>\n<li>\u3053\u308c\u307e\u3067\u306e\u624b\u6cd5\u306f\u6642\u9593\u306e\u7d4c\u904e\u306b\u4f34\u3046\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u5316\u3092\u63a8\u5b9a\u3067\u304d\u306a\u304b\u3063\u305f\u3002<\/li>\n<li>\u6642\u9593\u306e\u7d4c\u904e\u306b\u4f34\u3046\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u5316\u3092\u63a8\u5b9a\u3059\u308b\u624b\u6cd5Umibato\u3092\u958b\u767a\u3057\u305f\u3002<\/li>\n<li>\u81ea\u7136\u74b0\u5883\u306e\u751f\u614b\u7cfb\u306e\u89e3\u660e\u3084\u3001\u8fd1\u5e74\u6025\u901f\u306b\u89e3\u660e\u304c\u9032\u3093\u3067\u3044\u308b\u30d2\u30c8\u5e38\u5728\u83cc\u53e2\u306e\u9577\u671f\u7684\u306a\u5909\u5316\u306e\u8ffd\u8de1\u306b\u304a\u3044\u3066\u6d3b\u7528\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n<p>\u65e9\u7a32\u7530\u5927\u5b66\u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1\u5f8c\u671f\u535a\u58eb\u8ab2\u7a0b3\u5e74\u306e\u7d30\u7530 \u81f3\u6e29\uff08\u307b\u305d\u3060 \u3057\u304a\u3093\uff09\u6c0f\u3068\u3001\u540c\u5927\u7406\u5de5\u5b66\u8853\u9662\u306e<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001261_ja.html\">\u6d5c\u7530 \u9053\u662d\uff08\u306f\u307e\u3060 \u307f\u3061\u3042\u304d\uff09\u6559\u6388<\/a>\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6642\u9593\u306e\u7d4c\u904e\u306b\u4f34\u3046\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u5316\u3092\u63a8\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u624b\u6cd5Umibato \uff08unsupervised learning-based microbial interaction inference method using Bayesian estimation\uff09\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u308c\u307e\u3067\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u3092\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306b\u7528\u3044\u3089\u308c\u3066\u3044\u305f\u624b\u6cd5\u306f\u3001\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u304c\u6642\u9593\u306b\u4f34\u3044\u5909\u5316\u3057\u306a\u3044\u3053\u3068\u3092\u524d\u63d0\u3068\u3057\u3066\u3044\u305f\u305f\u3081\u3001\u6642\u9593\u306e\u7d4c\u904e\u306b\u4f34\u3044\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u304c\u5909\u5316\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u63a8\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4eca\u56de\u958b\u767a\u3057\u305f\u624b\u6cd5\u306b\u3088\u308a\u3001\u7d30\u83cc\u53e2\u306e\u6642\u7cfb\u5217\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u304a\u3044\u3066\u3053\u308c\u307e\u3067\u898b\u904e\u3054\u3055\u308c\u3066\u304d\u305f\u7d30\u83cc\u306e\u95a2\u4fc2\u6027\u306e\u5909\u5316\u3092\u6349\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u5c06\u6765\u7684\u306b\u306f\u3001\u81ea\u7136\u74b0\u5883\u306e\u751f\u614b\u7cfb\u306e\u89e3\u660e\u3084\u3001\u8fd1\u5e74\u6025\u901f\u306b\u89e3\u660e\u304c\u9032\u3093\u3067\u3044\u308b\u30d2\u30c8\u5e38\u5728\u83cc\u53e2\u306e\u9577\u671f\u7684\u306a\u5909\u5316\u306e\u8ffd\u8de1\u306b\u304a\u3044\u3066\u6d3b\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012021\u5e747\u6708\u672b\u306b\u958b\u50ac\u3055\u308c\u308b\u8a08\u7b97\u751f\u7269\u5b66\u306e\u30c8\u30c3\u30d7\u306e\u56fd\u969b\u4f1a\u8b70\u3067\u3042\u308bISMB\/ECCB2021\u306e\u53e3\u982d\u767a\u8868\u306b\u53d7\u7406\u3055\u308c\u307e\u3057\u305f\u3002\u8ad6\u6587\u306fISMB\/ECCB2021\u306e\u4e88\u7a3f\u3068\u3057\u30662021\u5e747\u670812\u65e5\uff08\u6708\uff09\uff08\u73fe\u5730\u6642\u9593\uff09\u306b\u300e<a href=\"https:\/\/academic.oup.com\/bioinformatics\">Bioinformatics<\/a>\u300f\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u8ad6\u6587\u540d\uff1a<a href=\"https:\/\/academic.oup.com\/bioinformatics\/article\/37\/Supplement_1\/i16\/6319692\">Umibato: estimation of time-varying microbial interaction using continuous-time regression hidden Markov model<\/a><\/p>\n<h4>(1)\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/h4>\n<p>\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306f\u3001\u6804\u990a\u306e\u3084\u308a\u3068\u308a\u306a\u3069\u306b\u3088\u308a\u7d30\u83cc\u540c\u58eb\u304c\u5f71\u97ff\u3057\u5408\u3046\u73fe\u8c61\u3067\u3059\u3002\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u306f\u4ee3\u8b1d\u30cd\u30c3\u30c8\u30ef\u30fc\u30af<sup>\u203b1<\/sup>\u3092\u69cb\u6210\u3059\u308b\u8981\u56e0\u3068\u3057\u3066\u5bbf\u4e3b\u306e\u5065\u5eb7\u306b\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u91cd\u8981\u306a\u7814\u7a76\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u306f\u3001\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u3092\u63a8\u5b9a\u3059\u308b\u305f\u3081\u306b\u3001\u4e00\u822c\u5316\u30ed\u30c8\u30ab\u30fb\u30f4\u30a9\u30eb\u30c6\u30e9\u65b9\u7a0b\u5f0f<sup>\u203b2<\/sup>\u3068\u3044\u3046\u5fae\u5206\u65b9\u7a0b\u5f0f\u3092\u30d9\u30fc\u30b9\u3068\u3057\u305f\u30e2\u30c7\u30eb\u304c\u5e83\u304f\u4f7f\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3053\u306e\u65b9\u7a0b\u5f0f\u306f\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u304c\u6642\u9593\u306b\u4f34\u3044\u5909\u5316\u3057\u306a\u3044\u3053\u3068\u3092\u524d\u63d0\u3068\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u4f55\u3089\u304b\u306e\u74b0\u5883\u6761\u4ef6\u304c\u5909\u5316\u3057\u305d\u308c\u306b\u4f34\u3044\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u304c\u5909\u5316\u3059\u308b\u3088\u3046\u306a\u5834\u5408\u306b\u9069\u7528\u304c\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f31\uff09\u3002\u73fe\u306b\u3001\u7570\u306a\u308b\u6804\u990a\u6761\u4ef6\u4e0b\u3067\u306f\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u304c\u7570\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u3059\u3067\u306b\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u3053\u306e\u6b20\u70b9\u306f\u81f4\u547d\u7684\u3067\u3057\u305f\u3002<\/p>\n<div id=\"attachment_73856\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-73856 size-thumbnail\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/795316b92fc766b0181f6fef074f03fa-2-360x270.png\" alt=\"\" width=\"360\" height=\"270\" \/><p 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id=\"attachment_73858\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-73858 size-full\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/c8856789ec11ab8b1013037cef6929f9-1.png\" alt=\"\" width=\"2617\" height=\"889\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/c8856789ec11ab8b1013037cef6929f9-1.png 2617w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/c8856789ec11ab8b1013037cef6929f9-1-610x207.png 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/c8856789ec11ab8b1013037cef6929f9-1-768x261.png 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2021\/07\/c8856789ec11ab8b1013037cef6929f9-1-2000x679.png 2000w\" sizes=\"auto, (max-width: 2617px) 100vw, 2617px\" \/><p class=\"wp-caption-text\">\u56f33\uff1a\u63a8\u5b9a\u3055\u308c\u305f\u76f8\u4e92\u4f5c\u7528\u306e\u5909\u9077\u30027\u3064\u306e\u30b0\u30e9\u30d5\u306f\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u30de\u30a6\u30b9\u306e\u8178\u5185\u7d30\u83cc\u53e2\u30c7\u30fc\u30bf\u306b\u5bfe\u5fdc\u3059\u308b\u7d50\u679c\u3067\u3001Subject4\u3068Subject7\u306f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u3059\u306a\u308f\u3061\u4f4e\u7e4a\u7dad\u98df\u3092\u6442\u3063\u3066\u3044\u306a\u3044\u30de\u30a6\u30b9\u306e\u30c7\u30fc\u30bf\u3067\u3042\u308b\u3002\u6a2a\u8ef8\u306f\u6642\u9593\u3092\u793a\u3057\u3001\u7e26\u8ef8\u306f\u76f8\u4e92\u4f5c\u7528\u306e\u7a2e\u985e\u3068\u4f4e\u7e4a\u7dad\u98df\u3092\u793a\u3059\u3002\u4f4e\u7e4a\u7dad\u98df\u30685\u7a2e\u76ee\u306e\u76f8\u4e92\u4f5c\u7528\uff08State5\uff09\u306e\u95a2\u9023\u304c\u898b\u3089\u308c\u308b\u3002<\/p><\/div>\n<h4>(3)\u305d\u306e\u305f\u3081\u306b\u65b0\u3057\u304f\u958b\u767a\u3057\u305f\u624b\u6cd5<\/h4>\n<p>\u96a0\u308c\u30de\u30eb\u30b3\u30d5\u30e2\u30c7\u30eb<sup>\u203b3<\/sup>\u3092\u62e1\u5f35\u3057\u305f\u9023\u7d9a\u6642\u9593\u56de\u5e30\u96a0\u308c\u30de\u30eb\u30b3\u30d5\u30e2\u30c7\u30eb\u3092\u63d0\u6848\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u3053\u306e\u30e2\u30c7\u30eb\u306e\u30d1\u30e9\u30e1\u30bf\u63a8\u5b9a\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3092\u5c0e\u51fa\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u3053\u306e\u30e2\u30c7\u30eb\u3068\u30ac\u30a6\u30b9\u904e\u7a0b\u56de\u5e30<sup>\u203b4<\/sup>\u306b\u3088\u308b\u7d30\u83cc\u6210\u9577\u7387\u63a8\u5b9a\u3092\u7528\u3044\u3066\u3001\u6642\u9593\u5909\u5316\u3059\u308b\u76f8\u4e92\u4f5c\u7528\u3092\u8003\u616e\u3057\u305f\u4e00\u822c\u5316\u30ed\u30c8\u30ab\u30fb\u30f4\u30a9\u30eb\u30c6\u30e9\u65b9\u7a0b\u5f0f\u306b\u57fa\u3065\u304f\u7d30\u83cc\u76f8\u4e92\u4f5c\u7528\u63a8\u5b9a\u624b\u6cd5Umibato\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/p>\n<h4>(4)\u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c\u3084\u793e\u4f1a\u7684\u5f71\u97ff<\/h4>\n<p>\u8907\u96d1\u306a\u6319\u52d5\u3092\u898b\u305b\u308b\u3053\u3068\u306e\u591a\u3044\u6642\u7cfb\u5217\u7d30\u83cc\u53e2\u30c7\u30fc\u30bf\u306e\u89e3\u6790\u306b\u304a\u3044\u3066\u3053\u308c\u307e\u3067\u898b\u904e\u3054\u3055\u308c\u3066\u304d\u305f\u7d30\u83cc\u306e\u95a2\u4fc2\u6027\u306e\u5909\u5316\u3092\u6349\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u81ea\u7136\u74b0\u5883\u306e\u751f\u614b\u7cfb\u306e\u89e3\u660e\u3084\u3001\u8fd1\u5e74\u6025\u901f\u306b\u89e3\u660e\u304c\u9032\u3093\u3067\u3044\u308b\u30d2\u30c8\u5e38\u5728\u83cc\u53e2\u306e\u9577\u671f\u7684\u306a\u5909\u5316\u306e\u8ffd\u8de1\u306b\u304a\u3044\u3066\u5927\u3044\u306b\u6d3b\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<h4>(5)\u4eca\u5f8c\u306e\u8ab2\u984c<\/h4>\n<p>\u4e3b\u306a\u8ab2\u984c\u3068\u3057\u3066\u3001\u4e8c\u3064\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u4e00\u3064\u306f\u3001\u66f4\u306a\u308b\u5b9f\u30c7\u30fc\u30bf\u3078\u306e\u9069\u7528\u3067\u3059\u3002\u516c\u958b\u3055\u308c\u3066\u3044\u308b\u30c7\u30fc\u30bf\u306e\u5236\u9650\u304b\u3089\u3001\u4eca\u56de\u306f\u30de\u30a6\u30b9\u8178\u5185\u7d30\u83cc\u53e2\u30c7\u30fc\u30bf\u306b\u5bfe\u3059\u308b\u9069\u7528\u306b\u7559\u307e\u308a\u307e\u3057\u305f\u304c\u3001Umibato\u306f\u3042\u3089\u3086\u308b\u74b0\u5883\u306e\u6642\u7cfb\u5217\u5b9a\u91cf\u7d30\u83cc\u53e2\u30c7\u30fc\u30bf\u3067\u9069\u7528\u53ef\u80fd\u306a\u624b\u6cd5\u3067\u3059\u3002\u3082\u3046\u4e00\u3064\u306f\u3001\u5b9f\u9a13\u306b\u3088\u308b\u63a8\u5b9a\u3055\u308c\u305f\u76f8\u4e92\u4f5c\u7528\u306e\u691c\u8a3c\u3067\u3059\u3002\u672c\u7814\u7a76\u3067\u63a8\u5b9a\u3055\u308c\u305f\u95a2\u4fc2\u6027\u3092\u5b9f\u9a13\u7684\u306b\u691c\u8a3c\u3059\u308b\u3053\u3068\u3067\u3001\u63a8\u5b9a\u3055\u308c\u305f\u76f8\u4e92\u4f5c\u7528\u306e\u89e3\u660e\u306b\u7e4b\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<h4>(6)\u7814\u7a76\u8005\u306e\u30b3\u30e1\u30f3\u30c8<\/h4>\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001\u9577\u3044\u6b74\u53f2\u3092\u6301\u3061\u3053\u308c\u307e\u3067\u5e83\u304f\u4f7f\u308f\u308c\u3066\u304d\u305f\u65b9\u7a0b\u5f0f\u3092\u3001\u73fe\u4ee3\u7684\u306a\u30c7\u30fc\u30bf\u306b\u5bfe\u3057\u3088\u308a\u5408\u7406\u7684\u306b\u6271\u3048\u308b\u3088\u3046\u6607\u83ef\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u3068\u611f\u3058\u3066\u3044\u307e\u3059\u3002\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u306b\u304a\u3044\u3066\u3001\u8208\u5473\u6df1\u3044\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u751f\u7269\u5b66\u7684\u610f\u7fa9\u3067\u306e\u5b9f\u7528\u6027\u306b\u6b20\u3051\u308b\u3053\u3068\u3082\u591a\u3044\u3067\u3059\u304c\u3001\u672c\u624b\u6cd5\u3067\u306f\u305d\u308c\u3089\u3092\u4e21\u7acb\u3067\u304d\u305f\u3068\u601d\u3044\u307e\u3059\u3002\u672c\u624b\u6cd5\u304c\u7d30\u83cc\u53e2\u7814\u7a76\u306e\u4e00\u52a9\u3068\u306a\u308a\u3001\u81ea\u7136\u74b0\u5883\u3084\u30d2\u30c8\u5e38\u5728\u83cc\u53e2\u306e\u89e3\u660e\u3092\u4fc3\u9032\u3067\u304d\u308c\u3070\u5e78\u3044\u3067\u3059\u3002<\/p>\n<h4>(7)\u7528\u8a9e\u89e3\u8aac<\/h4>\n<p>\u203b1\u3000\u4ee3\u8b1d\u30cd\u30c3\u30c8\u30ef\u30fc\u30af<br \/>\n\u3053\u3053\u3067\u306f\u5fae\u751f\u7269\u540c\u58eb\u306e\u4ee3\u8b1d\u7269\u306e\u3084\u308a\u3068\u308a\u3067\u69cb\u6210\u3055\u308c\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3002\u305f\u3068\u3048\u3070\u3001\u30d2\u30c8\u8178\u5185\u7d30\u83cc\u53e2\u3067\u306f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u3088\u308a\u6700\u7d42\u7684\u306b\u7523\u751f\u3055\u308c\u305f\u4ee3\u8b1d\u7269\u304c\u30d2\u30c8\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/p>\n<p>\u203b2\u3000\u4e00\u822c\u5316\u30ed\u30c8\u30ab\u30fb\u30f4\u30a9\u30eb\u30c6\u30e9\u65b9\u7a0b\u5f0f<br \/>\n\u6355\u98df\u8005\u3068\u88ab\u6355\u98df\u8005\u306e\u500b\u4f53\u6570\u3092\u8868\u73fe\u3059\u308b\u5fae\u5206\u65b9\u7a0b\u5f0f\u3067\u3042\u308b\u30ed\u30c8\u30ab\u30fb\u30f4\u30a9\u30eb\u30c6\u30e9\u65b9\u7a0b\u5f0f\u3092\u4e00\u822c\u5316\u3057\u305f\u5fae\u5206\u65b9\u7a0b\u5f0f\u3002\u6355\u98df\u3068\u88ab\u6355\u98df\u306e\u3088\u3046\u306a\u95a2\u4fc2\u6027\u3060\u3051\u3067\u306a\u304f\u3001\u76f8\u5229\u5171\u751f\u95a2\u4fc2\uff08A\u3068B\u304c\u4e92\u3044\u306b\u5897\u52a0\u306b\u5bc4\u4e0e\u3059\u308b\u95a2\u4fc2\uff09\u3084\u5bc4\u751f\u95a2\u4fc2\uff08A\u304cB\u306e\u5897\u52a0\u306b\u5bc4\u4e0e\u3001B\u306fA\u306e\u6e1b\u5c11\u306b\u5bc4\u4e0e\u3059\u308b\u95a2\u4fc2\uff09\u3082\u8868\u73fe\u3067\u304d\u308b\u305f\u3081\u7d30\u83cc\u53e2\u89e3\u6790\u3067\u3088\u304f\u7528\u3044\u3089\u308c\u308b\u3002<\/p>\n<p>\u203b3\u3000\u96a0\u308c\u30de\u30eb\u30b3\u30d5\u30e2\u30c7\u30eb<br \/>\n\u97f3\u58f0\u4fe1\u53f7\u51e6\u7406\u3084\u914d\u5217\u89e3\u6790\u3067\u3088\u304f\u7528\u3044\u3089\u308c\u308b\u7d71\u8a08\u30e2\u30c7\u30eb\u3002\u96e2\u6563\u7684\u306a\u6642\u7cfb\u5217\u306e\u30c7\u30fc\u30bf\u304b\u3089\u96a0\u308c\u305f\u60c5\u5831\u306e\u5909\u9077\u3092\u63a8\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u672c\u7814\u7a76\u3067\u63d0\u6848\u3057\u305f\u9023\u7d9a\u6642\u9593\u56de\u5e30\u96a0\u308c\u30de\u30eb\u30b3\u30d5\u30e2\u30c7\u30eb\u306f\u96a0\u308c\u30de\u30eb\u30b3\u30d5\u30e2\u30c7\u30eb\u306e\u4e00\u7a2e\u3067\u3001\u5b9f\u6642\u9593\u306e\u3088\u3046\u306a\u9023\u7d9a\u7684\u306a\u6642\u7cfb\u5217\u3092\u6271\u3048\u308b\u3088\u3046\u62e1\u5f35\u3055\u308c\u305f\u30e2\u30c7\u30eb\u3067\u3042\u308b\u3002<\/p>\n<p>\u203b4\u3000\u30ac\u30a6\u30b9\u904e\u7a0b\u56de\u5e30<br \/>\n\u30ac\u30a6\u30b9\u904e\u7a0b\u3068\u3044\u3046\u78ba\u7387\u904e\u7a0b\u3092\u30d9\u30fc\u30b9\u3068\u3057\u305f\u56de\u5e30\u624b\u6cd5\u3002\u67d4\u8edf\u306a\u56de\u5e30\u3092\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u308b\u3002<\/p>\n<h4>(8)\u8ad6\u6587\u60c5\u5831<\/h4>\n<p>\u96d1\u8a8c\u540d\uff1a<a href=\"https:\/\/academic.oup.com\/bioinformatics\">Bioinformatics<\/a><br \/>\n\u8ad6\u6587\u540d\uff1a<a href=\"https:\/\/academic.oup.com\/bioinformatics\/article\/37\/Supplement_1\/i16\/6319692?searchresult=1\">Umibato: estimation of time-varying microbial interaction using continuous-time regression hidden Markov model<\/a><br \/>\n\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1aShion Hosoda\uff08\u65e9\u7a32\u7530\u5927\u5b66\u3001\u7523\u7dcf\u7814\u30fb\u65e9\u5927 \u751f\u4f53\u30b7\u30b9\u30c6\u30e0\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790 \u30aa\u30fc\u30d7\u30f3\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u30e9\u30dc\u30e9\u30c8\u30ea\uff09\u3001 Tsukasa Fukunaga\uff08\u65e9\u7a32\u7530\u5927\u5b66\u3001\u7814\u7a76\u5f53\u6642\uff1a\u6771\u4eac\u5927\u5b66\uff09\u3001<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001261_ja.html\">Michiaki Hamada<\/a>\uff08\u65e9\u7a32\u7530\u5927\u5b66\u3001\u7523\u7dcf\u7814\u30fb\u65e9\u5927 \u751f\u4f53\u30b7\u30b9\u30c6\u30e0\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790 \u30aa\u30fc\u30d7\u30f3\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u30e9\u30dc\u30e9\u30c8\u30ea\uff09<br \/>\n\u63b2\u8f09\u65e5\uff08\u73fe\u5730\u6642\u9593\uff09\uff1a2021\u5e747\u670812\u65e5\uff08\u6708\uff09<br \/>\n\u63b2\u8f09URL\uff1a<a href=\"https:\/\/doi.org\/10.1093\/bioinformatics\/btab287\">https:\/\/doi.org\/10.1093\/bioinformatics\/btab287<\/a><br \/>\nDOI\uff1a<a href=\"https:\/\/academic.oup.com\/bioinformatics\/article\/37\/Supplement_1\/i16\/6319692?searchresult=1\">10.1093\/bioinformatics\/btab287<\/a><\/p>\n<h4>(9)\u7814\u7a76\u52a9\u6210<\/h4>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u7814\u8cbb \u7279\u5225\u7814\u7a76\u54e1\u5968\u52b1\u8cbb<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a<a href=\"https:\/\/kaken.nii.ac.jp\/grant\/KAKENHI-PROJECT-19J20117\/\">\u78ba\u7387\u30e2\u30c6\u3099\u30eb\u3092\u7528\u3044\u305f\u30d2\u30c8\u8178\u5185\u7d30\u83cc\u53e2\u69cb\u9020\u306e\u89e3\u660e\u3068\u5fdc\u7528<\/a><br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u7d30\u7530 \u81f3\u6e29\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u7814\u8cbb \u65b0\u5b66\u8853\u9818\u57df\u7814\u7a76\uff08\u7814\u7a76\u9818\u57df\u63d0\u6848\u578b\uff09<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a<a href=\"https:\/\/kaken.nii.ac.jp\/ja\/grant\/KAKENHI-PUBLICLY-20H05582\/\">\u9006\u30a4\u30b8\u30f3\u30b0\u30e2\u30c7\u30eb\u6cd5\u306b\u57fa\u3065\u304f\u6a5f\u80fd\u672a\u77e5\u306a\u5fae\u751f\u7269\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u63a8\u5b9a<\/a><br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u798f\u6c38 \u6d25\u5d69\uff08\u6771\u4eac\u5927\u5b66 \u5f53\u6642\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08A\uff09<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a<a href=\"https:\/\/kaken.nii.ac.jp\/ja\/grant\/KAKENHI-PROJECT-20H00624\/\">\u30ea\u30d4\u30fc\u30c8\u8981\u7d20\u306ede novo\u767a\u898b\u306b\u57fa\u3065\u304f\u9577\u9396\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u306e\u6a5f\u80fd\u306e\u89e3\u660e<\/a><br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6d5c\u7530 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