{"id":69454,"date":"2020-06-15T12:00:46","date_gmt":"2020-06-15T03:00:46","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=69454"},"modified":"2020-06-23T11:24:03","modified_gmt":"2020-06-23T02:24:03","slug":"rna%e3%82%a2%e3%83%97%e3%82%bf%e3%83%9e%e3%83%bc%e5%89%b5%e8%a3%bd-%e6%96%b0%e6%89%8b%e6%b3%95%e9%96%8b%e7%99%ba%e3%81%ab%e6%88%90%e5%8a%9f-2","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/69454","title":{"rendered":"RNA\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u88fd 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href=\"https:\/\/www.waseda.jp\/fsci\/\">\u65e9\u7a32\u7530\u5927\u5b66\uff08\u6771\u4eac\u90fd\u65b0\u5bbf\u533a\uff1a\u7dcf\u9577\u3000\u7530\u4e2d\u611b\u6cbb\uff09\u7406\u5de5\u5b66\u8853\u9662<\/a>\u306e<a href=\"https:\/\/www.hamadalab.com\/\">\u6d5c\u7530\u9053\u662d\uff08\u306f\u307e\u3060\u307f\u3061\u3042\u304d\uff09\u6559\u6388<\/a>\u3001\u540c<a href=\"https:\/\/www.ase.sci.waseda.ac.jp\/\">\u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1<\/a>\u306e\u77f3\u7530\u907c\u6211\uff08\u3044\u3057\u3060\u308a\u3087\u3046\u304c\uff09\uff08\u4fee\u58eb\u8ab2\u7a0b\uff1a\u7814\u7a76\u5f53\u6642\uff09\u304a\u3088\u3073\u6a2a\u7530\u5f69\uff08\u3088\u3053\u305f\u3042\u3084\uff09\uff08\u540c\uff09\u306a\u3089\u3073\u306b\u3001\u682a\u5f0f\u4f1a\u793e\u30ea\u30dc\u30df\u30c3\u30af\uff08\u6771\u4eac\u90fd\u6e2f\u533a\uff1a\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\u3000\u4e2d\u6751\u7fa9\u4e00\uff09\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6b21\u4e16\u4ee3\u306e\u65b0\u85ac\u306e\u5019\u88dc\u3068\u306a\u308bRNA\u30a2\u30d7\u30bf\u30de\u30fc\uff08\u203b1\uff09\u3092\u3001\u5b9f\u9a13\u304b\u3089\u53d6\u5f97\u3055\u308c\u308b\u5927\u91cf\u306e\u914d\u5217\u5019\u88dc\u304b\u3089\u9ad8\u7cbe\u5ea6\u3067\u9078\u629e\u3057\u3001\u3055\u3089\u306b\u3001\u7d50\u5408\u306b\u91cd\u8981\u3068\u306a\u308b\u30e2\u30c1\u30fc\u30d5\u60c5\u5831\u3092\u63a8\u5b9a\u3059\u308b\u65b0\u624b\u6cd5RaptRanker\u3092\u958b\u767a\u3044\u305f\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u65b0\u3057\u304f\u53d6\u5f97\u3057\u305f\u5b9f\u9a13\u30c7\u30fc\u30bf\u3092\u7528\u3044\u305f\u8a55\u4fa1\u306b\u3088\u308a\u3001RaptRanker\u306e\u6709\u52b9\u6027\u3092\u793a\u3059\u3053\u3068\u306b\u6210\u529f\u3044\u305f\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012020\u5e746\u670815\u65e5\uff08\u6708\uff09\u5348\u524d0\u6642\uff08\u5354\u5b9a\u4e16\u754c\u6642\uff09\u306b\u82f1\u56fd\u306e<a href=\"https:\/\/global.oup.com\/?cc=jp\">Oxford University Press<\/a>\u304c\u767a\u884c\u3059\u308b\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u79d1\u5b66\u8a8c\u300c<a href=\"https:\/\/academic.oup.com\/nar\"><em>Nucleic Acids Research<\/em><\/a>\u300d\u3067\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h3><strong>\uff1c\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068\uff08\u79d1\u5b66\u53f2\u7684\u30fb\u6b74\u53f2\u7684\u306a\u80cc\u666f\u306a\u3069\uff09\uff1e<\/strong><\/h3>\n<p>\u73fe\u5728\u3001\u533b\u85ac\u54c1\u958b\u767a\u306b\u304a\u3044\u3066\u306f\u3001\u5275\u85ac\u6210\u529f\u7387\u306e\u4f4e\u4e0b\u3001\u5275\u85ac\u30d7\u30ed\u30bb\u30b9\u306e\u9577\u671f\u5316\u3068\u9ad8\u30b3\u30b9\u30c8\u5316\u304c\u5927\u304d\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u73fe\u5728\u4e3b\u6d41\u3068\u306a\u3063\u3066\u3044\u308b\u85ac\uff08\u4f4e\u5206\u5b50\u5316\u5408\u7269\uff09\u3067\u306f\u958b\u767a\u304c\u56f0\u96e3\u306a\u300c\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u300d\u306a\u3069\u306e\u96e3\u3057\u3044\u5275\u85ac\u30bf\u30fc\u30b2\u30c3\u30c8\u304c\u591a\u6570\u6b8b\u5b58\u3059\u308b\u3053\u3068\u304c\u4e00\u3064\u306e\u8981\u56e0\u3067\u3059\u3002<\/p>\n<p>\u4e00\u65b9\u3001\u7279\u5b9a\u306e\u5206\u5b50\u306b\u7279\u7570\u7684\u304b\u3064\u5f37\u304f\u7d50\u5408\u3092\u3059\u308bRNA\u306f\u300cRNA\u30a2\u30d7\u30bf\u30de\u30fc\u300d\uff08\u4ee5\u4e0b\u30a2\u30d7\u30bf\u30de\u30fc\uff09\u3068\u547c\u3070\u308c\u3001\u6b21\u4e16\u4ee3\u306e\u65b0\u85ac\u306e\u8981\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u958b\u767a\u30d7\u30ed\u30bb\u30b9\u306b\u304a\u3044\u3066\u306f\u3001\u307e\u305a\u3001HT-SELEX\uff08\u203b2\uff09\u3068\u547c\u3070\u308c\u308b\u5b9f\u9a13\u624b\u6cd5\u306b\u3088\u308a\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u306a\u308b\u5206\u5b50\u306b\u7d50\u5408\u3059\u308bRNA\u914d\u5217\u3092\u5927\u91cf\u306b\u53d6\u5f97\u3057\u3001\u305d\u306e\u4e2d\u304b\u3089\u5019\u88dc\u3068\u306a\u308b\u30a2\u30d7\u30bf\u30de\u30fc\u3092\u9078\u629e\u3057\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u9078\u629e\u3057\u305f\u5019\u88dc\u306b\u5bfe\u3057\u3066\u77ed\u9396\u5316\u306a\u3069\u306e\u6700\u9069\u5316\u3092\u884c\u3046\u3053\u3068\u306b\u3088\u308a\u3001\u6700\u7d42\u7684\u306a\u30a2\u30d7\u30bf\u30de\u30fc\u3092\u53d6\u5f97\u3059\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u306a\u65b9\u6cd5\u3068\u306a\u3063\u3066\u3044\u307e\u3059\uff08\u56f3\uff11\uff09\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u5b9f\u9a13\u8005\u306e\u7d4c\u9a13\u30fb\u52d8\u306b\u983c\u308b\u90e8\u5206\u304c\u591a\u304f\u3001\u8a66\u884c\u932f\u8aa4\u7684\u306b\u5b9f\u65bd\u3055\u308c\u591a\u5927\u306a\u6642\u9593\u30fb\u8cbb\u7528\u3092\u8981\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u304c\u30a2\u30d7\u30bf\u30de\u30fc\u666e\u53ca\u3092\u59a8\u3052\u3066\u3044\u308b\u4e00\u3064\u306e\u539f\u56e0\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<div id=\"attachment_69441\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69441 size-medium\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada2-610x319.jpg\" alt=\"\" width=\"610\" height=\"319\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada2-610x319.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada2.jpg 685w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\">\u56f3 1 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id=\"attachment_69440\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69440 size-full\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada1.jpg\" alt=\"\" width=\"601\" height=\"561\" \/><p class=\"wp-caption-text\">\u56f3 2 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id=\"attachment_69442\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-69442 size-medium\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada3-610x387.jpg\" alt=\"\" width=\"610\" height=\"387\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada3-610x387.jpg 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2020\/06\/hamada3.jpg 688w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\">\u56f33 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\u4e8c\u6b21\u69cb\u9020<\/h5>\n<ul>\n<li>RNA\u306e\u9ad8\u6b21\u69cb\u9020\u306e\u4e00\u3064\u3067\u3001\u6c34\u7d20\u7d50\u5408\u3092\u4ecb\u3057\u305f\u5869\u57fa\u5bfe\u306b\u3088\u308a\u8868\u73fe\u3055\u308c\u308b\u69cb\u9020\u3002\u30b9\u30c6\u30e0\u3001\u30d8\u30a2\u30d4\u30f3\u3001\u30d0\u30eb\u30b8\u3001\u5185\u90e8\u30eb\u30fc\u30d7\u3001\u5916\u90e8\u30eb\u30fc\u30d7\u306a\u3069\u306e\u69cb\u9020\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u3002\u4e8c\u6b21\u69cb\u9020\u306f\u7acb\u4f53\u69cb\u9020\u306b\u6298\u308c\u305f\u305f\u307e\u308c\u308b\u524d\u6bb5\u968e\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/li>\n<\/ul>\n<h5>\u203b\uff14 \u30e2\u30c1\u30fc\u30d5<\/h5>\n<ul>\n<li>\u7279\u5b9a\u306e\u6a5f\u80fd\uff08\u4eca\u56de\u306e\u5834\u5408\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\uff09\u306b\u91cd\u8981\u3068\u306a\u308b\u3001\u77ed\u3044\u914d\u5217\u3084\u69cb\u9020\u306e\u3053\u3068\u3002<\/li>\n<\/ul>\n<p><strong>\uff1c\u8ad6\u6587\u60c5\u5831\uff1e<\/strong><\/p>\n<p><strong>\u96d1\u8a8c\u540d\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/nar\">Nucleic Acids Research<\/a><br \/>\n<strong>\u8ad6\u6587\u540d\uff1a<\/strong><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkaa484\/5855635\">RaptRanker: <em>in silico<\/em> RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information<\/a><br \/>\n<strong>\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a<\/strong>Ryoga Ishida (\u65e9\u7a32\u7530\u5927\u5b66 \u5f53\u6642)\u3001Tatsuo Adachi\uff08\u30ea\u30dc\u30df\u30c3\u30af\uff09\u3001Aya Yokota\uff08\u65e9\u7a32\u7530\u5927\u5b66 \u5f53\u6642\uff09\u3001Hidehito Yoshihara(\u30ea\u30dc\u30df\u30c3\u30af)\u3001Kazuteru Aoki\uff08\u30ea\u30dc\u30df\u30c3\u30af\uff09\u3001Yoshikazu Nakamura\uff08\u30ea\u30dc\u30df\u30c3\u30af\uff09\u3001<a href=\"https:\/\/www.hamadalab.com\/\">Michiaki Hamada<\/a>\uff08\u65e9\u7a32\u7530\u5927\u5b66\u3001<a href=\"https:\/\/unit.aist.go.jp\/cbbd-oil\/\">\u7523\u7dcf\u7814\u30fb\u65e9\u5927 \u751f\u4f53\u30b7\u30b9\u30c6\u30e0\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790 \u30aa\u30fc\u30d7\u30f3\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u30e9\u30dc\u30e9\u30c8\u30ea<\/a>\uff09<br \/>\n<strong>\u63b2\u8f09\u4e88\u5b9a\u65e5\u6642\uff08\u73fe\u5730\u6642\u9593\uff09\uff1a2020\u5e746\u670815\u65e5 00:05 UTC<br \/>\n<\/strong><strong>\u63b2\u8f09\u4e88\u5b9a\u65e5\u6642\uff08\u65e5\u672c\u6642\u9593\uff09\uff1a2020\u5e746\u670815\u65e5 09:05 UTC<br \/>\n<\/strong><strong>\u63b2\u8f09\uff08\u4e88\u5b9a\uff09URL\uff1ahttps:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkaa484\/5855635<br \/>\n<\/strong><strong>DOI<\/strong><strong>\uff1a<\/strong> <strong>https:\/\/doi.org\/10.1093\/nar\/gkaa484<\/strong><\/p>\n<h3><strong>\uff1c\u7814\u7a76\u52a9\u6210\uff1e<\/strong><\/h3>\n<p><strong>\u7814\u7a76\u8cbb\u540d\uff1a<\/strong><a href=\"https:\/\/www.jst.go.jp\/kisoken\/crest\/\">JST\u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696d\uff08CREST\uff09<\/a><br \/>\n<strong>\u7814\u7a76\u8ab2\u984c\u540d\uff1a<\/strong><a href=\"https:\/\/www.jst.go.jp\/kisoken\/crest\/project\/1111094\/1111094_2018.html\">\u4eba\u5de5\u77e5\u80fd\u6280\u8853\u3092\u7528\u3044\u305f\u9769\u65b0\u7684\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a<\/a><br \/>\n<strong>\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a<\/strong><a href=\"https:\/\/www.hamadalab.com\/\">\u6d5c\u7530\u9053\u662d\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>RNA\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u88fd\u671f\u9593\u306e\u77ed\u7e2e\u306b\u6709\u52b9\u306a\u65b0\u624b\u6cd5RaptRanker\u3092\u958b\u767a \u6b21\u4e16\u4ee3\u65b0\u85ac\u958b\u767a\u6210\u529f\u7387\u306e\u5411\u4e0a\u3068\u30b3\u30b9\u30c8\u4f4e\u6e1b\u306b\u671f\u5f85 \u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8 \u3053\u308c\u307e\u3067\u6b21\u4e16\u4ee3\u65b0\u85ac\u5019\u88dcRNA\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u5275\u88fd\u306b\u306f\u591a\u5927\u306a\u6642\u9593\u3068\u8cbb\u7528\u3092\u8981\u3057\u3066\u3044\u305f RNA\u30a2 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":69440,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[357,5],"class_list":["post-69454","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/69454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=69454"}],"version-history":[{"count":0,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/69454\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/69440"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=69454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=69454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=69454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}