{"id":6544,"date":"2014-01-17T00:00:00","date_gmt":"2014-01-16T15:00:00","guid":{"rendered":"http:\/\/www.waseda.jp\/news\/6544"},"modified":"2014-12-19T10:43:51","modified_gmt":"2014-12-19T01:43:51","slug":"%e6%b0%b4%e4%b8%ad%e3%81%a7%e8%a7%a6%e3%82%8c%e3%81%9a%e3%81%ab%e7%b4%b0%e8%83%9e%e3%81%ae%e4%b8%ad%e3%81%ae%e6%b8%a9%e5%ba%a6%e3%82%92%e6%b8%ac%e3%82%8c%e3%82%8b%e3%83%ac%e3%82%b7%e3%82%aa%e5%9e%8b","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/6544","title":{"rendered":"\u6c34\u4e2d\u3067\u89e6\u308c\u305a\u306b\u7d30\u80de\u306e\u4e2d\u306e\u6e29\u5ea6\u3092\u6e2c\u308c\u308b\u30ec\u30b7\u30aa\u578b\u30ca\u30ce\u6e29\u5ea6\u8a08\u3092\u958b\u767a \u30df\u30af\u30ed\u30f3\u30b5\u30a4\u30ba\u306e\u6e29\u5ea6\u5909\u5316\u3092\u6e2c\u5b9a\u3059\u308b\u30ca\u30ce\u6e29\u5ea6\u8a08\u306e\u624b\u6cd5\u3092\u767a\u5c55"},"content":{"rendered":"

\u65e9\u7a32\u7530\u5927\u5b66 \u65e9\u7a32\u7530\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7814\u7a76\u6240\uff08WABIOS\uff09<\/small>\u306e\u9234\u6728\u56e3\u4e3b\u4efb\u7814\u7a76\u54e1\u3001\u7406\u5de5\u5b66\u8853\u9662\u306e\u6b66\u5ca1\u771f\u53f8\u6559\u6388\u3001\u540c\u5927\u5927\u5b66\u9662\u751f\u306e\u6b66\u4e95\u7fa9\u660e\u6c0f\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u30012012\u5e74\u3001\u52d5\u7269\u306e\u7d30\u80de\u5185\u306e\u5c40\u6240\u7684\u304b\u3064\u308f\u305a\u304b\u306a\u6e29\u5ea6\u5909\u5316\u306e\u6e2c\u5b9a\u3092\u53ef\u80fd\u306b\u3059\u308b\u7d30\u80de\u5185\u3092\u6b69\u304f\u30ca\u30ce\u6e29\u5ea6\u8a08\u3092\u958b\u767a\u3057\u305f\u306e\u306b\u7d9a\u304d\u3001\u6c34\u4e2d\u3067\u89e6\u308c\u308b\u3053\u3068\u306a\u304f\u7d30\u80de\u306e\u4e2d\u306e\u6e29\u5ea6\u3092\u6e2c\u5b9a\u3059\u308b\u300c\u30ec\u30b7\u30aa\u578b\u30ca\u30ce\u6e29\u5ea6\u8a08\u300d\u306e\u958b\u767a\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u307e\u3067\u306e\u86cd\u5149\u5f37\u5ea6\u3092\u6e2c\u308b\u30ca\u30ce\u6e29\u5ea6\u8a08\u3067\u306f\u3001\u5bfe\u8c61\u306e\u6e29\u5ea6\u5909\u5316\u306e\u307f\u306e\u6e2c\u5b9a\u3067\u3057\u305f\u304c\u3001\u4eca\u56de\u306e\u958b\u767a\u3067\u306f\u7d30\u80de\u304c\u52d5\u3044\u3066\u3082\u6b63\u3057\u3044\u6e29\u5ea6\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u300cA Nanoparticle-Based Ratiometric and Self-Calibrated Fluorescent Thermometer for Single Living Cells\u300d\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u3067\u7c73\u56fd\u5316\u5b66\u4f1a\uff08ACS\uff09<\/small>\u767a\u884c\u306e\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u5c02\u9580\u8a8c\u300eACS Nano\u300f\u306b\u63b2\u8f09\u4e88\u5b9a\u3067\u3001\u305d\u308c\u306b\u5148\u7acb\u3061\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\u306b\u63b2\u8f09\uff082013\u5e7412\u670819\u65e5\uff09<\/small>\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u672c\u7814\u7a76\u306e\u80cc\u666f\u3068\u76ee\u7684<\/h5>\n

\u6e29\u71b1\u7642\u6cd5\u306e\u5206\u91ce\u306a\u3069\u3001\u751f\u30fb\u533b\u5b66\u5206\u91ce\u306e\u7814\u7a76\u958b\u767a\u306b\u304a\u3044\u3066\u306f\u3001\u751f\u4f53\u306e\u5404\u90e8\u4f4d\u306e\u7d30\u304b\u3044\u6e29\u5ea6\u5206\u5e03\u3068\u305d\u306e\u6642\u9593\u5909\u5316\u3092\u6349\u3048\u308b\u3053\u3068\u304c\u91cd\u8981\u306a\u5834\u9762\u304c\u591a\u3005\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u969b\u3001\u5bb6\u5ead\u3067\u7528\u3044\u308b\u6e29\u5ea6\u8a08\u3067\u3082\u6e29\u5ea6\u611f\u5ea6\u306f\u5341\u5206\u306a\u306e\u3067\u3059\u304c\u3001\u6b63\u78ba\u306a\u8a08\u6e2c\u306b\u306f\u6642\u9593\u304c\u304b\u304b\u308a\uff08\uff15\u301c\uff11\uff10\u5206\u7a0b\uff09<\/small>\u3001\u307e\u305f\u7d30\u80de\u3092\u5bfe\u8c61\u306b\u8a08\u6e2c\u3059\u308b\u306b\u306f\u6e29\u5ea6\u8a08\u304c\u5927\u304d\u3059\u304e\u307e\u3059\u3002\u307e\u305f\u3001\u8d64\u5916\u7dda\u30ab\u30e1\u30e9\u3067\u6e29\u5ea6\u306e\u5e83\u304c\u308a\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u3059\u304c\u3001\u30df\u30af\u30ed\u306a\u6e29\u5ea6\u306e\u69d8\u5b50\u3084\u6642\u9593\u5909\u52d5\u3092\u8ffd\u3046\u306b\u306f\u4e0d\u5341\u5206\u306a\u73fe\u72b6\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u4ee5\u524d\u3001\u9234\u6728\u4e3b\u4efb\u7814\u7a76\u54e1\u3001\u6b66\u5ca1\u6559\u6388\u3001\u304a\u3088\u3073\u77f3\u6e21\u6559\u6388\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u958b\u767a\u3057\u305f\u86cd\u5149\u5f37\u5ea6\u3092\u6e2c\u308b\u30ca\u30ce\u6e29\u5ea6\u8a08\u306e\u8a08\u6e2c\u6cd5\u3067\u306f\u6e29\u5ea6\u5909\u5316\u3057\u304b\u308f\u304b\u3089\u306a\u3044\u305f\u3081\u3001\u5358\u4e00\u7d30\u80de\u30ec\u30d9\u30eb\uff08\u5927\u304d\u3055\u3001\u611f\u5ea6\u3001\u901f\u5ea6\uff09<\/small>\u3067\u6e2c\u5b9a\u3067\u304d\u308b\u6e29\u5ea6\u8a08\u3068\u8a08\u6e2c\u6cd5\u3092\u78ba\u7acb\u3059\u308b\u5fc5\u8981\u6027\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u672c\u7814\u7a76\u3067\u958b\u767a\u3057\u305f\u65b0\u3057\u3044\u624b\u6cd5<\/h5>\n

\u305d\u306e\u305f\u3081\u3001\u6c34\u4e2d\u3067\u89e6\u308c\u308b\u3053\u3068\u306a\u304f\u6e29\u5ea6\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3067\u304d\u308b\u65b0\u3057\u3044\u6280\u8853\u3001\u300c\u30ec\u30b7\u30aa\u578b\u30ca\u30ce\u6e29\u5ea6\u8a08\u300d\u306e\u958b\u767a\u3092\u884c\u3044\u307e\u3057\u305f\uff08\u30ec\u30b7\u30aa\uff1b2\u3064\u306e\u5024\u306e\u6bd4\u7387\uff09<\/small>\u3002\u86cd\u5149\u9855\u5fae\u93e1\u3092\u7528\u3044\u308b\u4ed6\u306e\u89b3\u5bdf\u30fb\u8a08\u6e2c\u624b\u6cd5\u3068\u9ad8\u3044\u89aa\u548c\u6027\u304c\u3042\u308a\u3001\u4e00\u822c\u7684\u306a\u751f\u30fb\u533b\u5b66\u7814\u7a76\u306e\u624b\u6cd5\u3068\u4f75\u7528\u53ef\u80fd\u306a\u65b9\u6cd5\u3067\u3059\u3002\u6e29\u5ea6\u306b\u5fdc\u7b54\u3059\u308bEu-TTA\u3068\u3044\u3046\u86cd\u5149\u8272\u7d20\uff08A\uff09<\/small>\u3068\u3001\u5fdc\u7b54\u3057\u306a\u3044Rhodamine 101\u3068\u3044\u3046\u86cd\u5149\u8272\u7d20\uff08B\uff09<\/small>\u3092\u6df7\u305c\u3066\u3001\u4e00\u3064\u306e\u7c92\u5b50\u306e\u4e2d\u306b\u9589\u3058\u3053\u3081\u307e\u3059\u3002\u305d\u306eA\u3068B\u306e\u5024\u306e\u6bd4\u7387A\/B\uff08\u30ec\u30b7\u30aa\uff09<\/small>\u3092\u6e2c\u308b\u3053\u3068\u3067\u3001\u30ec\u30b7\u30aa\u3068\u6e29\u5ea6\u3092\u4e00\u5bfe\u4e00\u306b\u5bfe\u5fdc\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u307e\u305f\u30ec\u30b7\u30aa\u306f\u9855\u5fae\u93e1\u306e\u7126\u70b9\u305a\u308c\u306b\u5f71\u97ff\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002pH\uff084-10\uff09<\/small>\u3001\u30a4\u30aa\u30f3\u5f37\u5ea6\uff080-500 mM\uff09<\/small>\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6fc3\u5ea6\uff08\u725b\u8840\u6e05\u30a2\u30eb\u30d6\u30df\u30f30-45 wt%\uff09<\/small>\u3001\u7c98\u6027\uff081-220 cP\uff09<\/small>\u3068\u3044\u3063\u305f\u5916\u90e8\u74b0\u5883\u306b\u5fdc\u7b54\u305b\u305a\u3001\u6e29\u5ea6\u3060\u3051\u3092\u6e2c\u308b\u3053\u3068\u3082\u672c\u958b\u767a\u306e\u7279\u5fb4\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u3067\u5f97\u3089\u308c\u305f\u7d50\u679c\u3068\u77e5\u898b<\/h5>\n

\u4eca\u56de\u3001\u30ec\u30b7\u30aa\u578b\u30ca\u30ce\u6e29\u5ea6\u8a08\u3092\u30d2\u30c8\u7531\u6765\u304c\u3093\u7d30\u80de\u30e2\u30c7\u30eb\u3067\u3042\u308bHeLa\u7d30\u80de\u306b\u5fdc\u7528\u3057\u307e\u3057\u305f\u3002\u691c\u8a3c\u3057\u305f\u3068\u3053\u308d\u3001\u7d30\u80de\u304c\u52d5\u3044\u3066\u3082\u6b63\u3057\u304f\u6e29\u5ea6\u3092\u6e2c\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u523a\u6fc0\u306e\u7121\u3044\u3068\u304d\u306b\u306f\u3001\u7d30\u80de\u306e\u4e2d\u3068\u5916\u3068\u3067\u6e29\u5ea6\u5dee\u304c\u307f\u3048\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u7d30\u80de\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u30a4\u30aa\u30f3\uff08Ca2+\uff09<\/small>\u6fc3\u5ea6\u3092\u5f37\u5236\u7684\u306b\u4e0a\u3052\u308b\u8a66\u85ac\u3092\u52a0\u3048\u308b\u3068\u3001\u7d30\u80de\u306e\u5185\u90e8\u3067\u6e29\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u3055\u3089\u306b\u7d30\u80de\u306e\u5834\u6240\u3054\u3068\u306b\u4e0a\u6607\u306e\u7a0b\u5ea6\u3068\u30bf\u30a4\u30df\u30f3\u30b0\u304c\u7570\u306a\u308a\u307e\u3057\u305f\u3002\u7d30\u80de\u5168\u4f53\u3067\u306f\u7d30\u80de\u5185Ca2+\u6fc3\u5ea6\u306e\u5909\u5316\u304c\u5927\u304d\u3044\u307b\u3069\u6e29\u5ea6\u4e0a\u6607\u3082\u5927\u304d\u304b\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u3053\u3053\u3067\u898b\u3089\u308c\u305f\u6e29\u5ea6\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u71b1\u6e90\u306f\u3001Ca2+\u306e\u6fc3\u5ea6\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002<\/p>\n

\"140117_nanothermo1\"

\u958b\u767a\u3057\u305f\u30ca\u30ce\u6e29\u5ea6\u8a08\u306e\u7279\u5fb4\u3068\u6a5f\u80fd<\/p><\/div>\n

\u672c\u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c<\/h5>\n

\u4eca\u56de\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u6e29\u5ea6\u5909\u5316\u3092\u5229\u7528\u3059\u308b\u30c9\u30e9\u30c3\u30b0\u30c7\u30ea\u30d0\u30ea\u30fc\u30b7\u30b9\u30c6\u30e0\uff08DDS\uff1b\u5fae\u5c0f\u7c92\u5b50\u306e\u4e2d\u306b\u9589\u3058\u8fbc\u3081\u3089\u308c\u305f\u85ac\u3092\u9069\u5207\u306a\u5834\u6240\u306b\u3001\u9069\u5207\u306a\u30bf\u30a4\u30df\u30f3\u30b0\u3067\u3001\u9069\u5207\u306a\u91cf\u3060\u3051\u6295\u4e0e\u3059\u308b\u65b9\u6cd5\u3002\u526f\u4f5c\u7528\u306e\u5927\u5e45\u306a\u8efd\u6e1b\u306a\u3069\u306e\u30e1\u30ea\u30c3\u30c8\u304c\u671f\u5f85\u3055\u308c\u308b\u3002\uff09<\/small>\u306e\u958b\u767a\u30fb\u6539\u826f\u306b\u304a\u3044\u3066\u5f53\u8a72\u6280\u8853\u3092\u5229\u7528\u3067\u304d\u307e\u3059\u3002\u5b9f\u969b\u3001\u81e8\u5e8a\u8a66\u9a13\u306b\u9032\u3093\u3067\u3044\u308b\u523a\u6fc0\u5fdc\u7b54\u6027DDS\u306e\u591a\u304f\u306f\u5916\u90e8\u304b\u3089\u64cd\u4f5c\u3055\u308c\u308b\u6e29\u5ea6\u5909\u5316\u3092\u5229\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u305d\u306e\u5229\u7528\u52b9\u679c\u306f\u9ad8\u3044\u3068\u898b\u8fbc\u307e\u308c\u307e\u3059\u3002\u307e\u305f\u6e29\u71b1\u7642\u6cd5\u3084\u3001\u5de5\u5b66\u7684\u7528\u9014\u3068\u3057\u3066\u306f\u305f\u3068\u3048\u3070\u5fae\u5c0f\u6d41\u8def\u30c7\u30d0\u30a4\u30b9\u306a\u3069\u3078\u306e\u5fdc\u7528\u3082\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u8ad6\u6587\u984c\u76ee<\/h4>\n

A Nanoparticle-Based Ratiometric and Self-Calibrated Fluorescent Thermometer for Single Living Cells\u30ec\u30b7\u30aa\u6e2c\u5b9a\u306b\u3088\u308b\u81ea\u5df1\u6821\u6b63\u6a5f\u80fd\u3092\u6301\u3064\u30ca\u30ce\u7c92\u5b50\u578b\u306e\u7d30\u80de\u7528\u86cd\u5149\u6e29\u5ea6\u8a08<\/p>\n

\u8457\u8005<\/h4>\n

\u6b66\u4e95\u7fa9\u660e1\u30fb\u65b0\u4e95\u654f2\u30fb\u6751\u7530\u7be41\u30fb\u9ad8\u6797\u660c\u751f1\u30fb\u5927\u5c71\u5ee3\u592a\u90ce3\u30fb\u77f3\u6e21\u4fe1\u4e002,3,4\u30fb\u6b66\u5ca1\u771f\u53f81,2,4,*\u30fb\u9234\u6728\u56e32,4,* \uff081\u65e9\u7a32\u7530\u5927\u30fb\u5148\u9032\u7406\u5de5\u30fb\u751f\u547d\u533b\u79d1\u30012\u65e9\u7a32\u7530\u5927\u30fb\u65e9\u7a32\u7530\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7814\u7a76\u6240\uff08WABIOS\uff09<\/small>\u30013\u65e9\u7a32\u7530\u5927\u30fb\u5148\u9032\u7406\u5de5\u30fb\u7269\u7406\u30014\u65e9\u7a32\u7530\u5927\u30fb\u91cd\u70b9\u6a5f\u69cb\u3001*Corresponding authors\uff09<\/small><\/p>\n

ACS Nano\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\uff082013\u5e7412\u670819\u65e5\u73fe\u5728\uff09<\/a><\/p>\n

\u65e9\u7a32\u7530\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7814\u7a76\u6240\uff08WABIOS\uff09<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u65e9\u7a32\u7530\u5927\u5b66 \u65e9\u7a32\u7530\u30d0\u30a4\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7814\u7a76\u6240\uff08WABIOS\uff09\u306e\u9234\u6728\u56e3\u4e3b\u4efb\u7814\u7a76\u54e1\u3001\u7406\u5de5\u5b66\u8853\u9662\u306e\u6b66\u5ca1\u771f\u53f8\u6559\u6388\u3001\u540c\u5927\u5927\u5b66\u9662\u751f\u306e\u6b66\u4e95\u7fa9\u660e\u6c0f\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u30012012\u5e74\u3001\u52d5\u7269\u306e\u7d30\u80de\u5185\u306e\u5c40\u6240\u7684\u304b\u3064\u308f\u305a\u304b\u306a\u6e29\u5ea6\u5909\u5316\u306e\u6e2c\u5b9a\u3092\u53ef\u80fd\u306b […]<\/p>\n","protected":false},"author":2,"featured_media":6566,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[186,5],"class_list":["post-6544","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-tech","tag-research","lang-ja"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=6544"}],"version-history":[{"count":1,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6544\/revisions"}],"predecessor-version":[{"id":63403,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6544\/revisions\/63403"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6566"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=6544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=6544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=6544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}