{"id":63209,"date":"2019-01-22T14:55:00","date_gmt":"2019-01-22T05:55:00","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=63209"},"modified":"2019-01-22T15:01:34","modified_gmt":"2019-01-22T06:01:34","slug":"%e5%8e%9f%e7%99%ba%e6%80%a7%e7%a1%ac%e5%8c%96%e6%80%a7%e8%83%86%e7%ae%a1%e7%82%8e%e3%81%ae%e7%97%85%e6%85%8b%e3%81%ab%e9%96%a2%e4%b8%8e%e3%81%99%e3%82%8b%e8%85%b8%e5%86%85%e7%b4%b0%e8%8f%8c%e3%82%92","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/63209","title":{"rendered":"\u539f\u767a\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u306e\u75c5\u614b\u306b\u95a2\u4e0e\u3059\u308b\u8178\u5185\u7d30\u83cc\u3092\u767a\u898b"},"content":{"rendered":"<h2>\u8178\u5185\u7d30\u83cc\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85<\/h2>\n<p>\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u306e<a href=\"http:\/\/researchers.waseda.jp\/profile\/ja.0aa298552ceee7f39ea1244ff5e50c84.html\" target=\"_blank\" rel=\"noopener\">\u670d\u90e8\u6b63\u5e73\uff08\u306f\u3063\u3068\u308a\u307e\u3055\u3072\u3089\uff09\u6559\u6388<\/a>\u306f\u3001\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u7b49\u3068\u5171\u540c\u3067\u3001\u809d\u79fb\u690d\u4ee5\u5916\u306b\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u5c11\u306a\u3044\u96e3\u6cbb\u6027\u81ea\u5df1\u514d\u75ab\u6027\u75be\u60a3\u3067\u3042\u308b\u539f\u767a\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\uff08PSC\uff09\u60a3\u8005\u306e\u4fbf\u4e2d\u306b\u3001\u809d\u81d3\u5185\u306eTH17\u7d30\u80de\uff08\u6ce81\uff09\u306e\u6d3b\u6027\u5316\u3092\u5f15\u304d\u8d77\u3053\u30593\u7a2e\u985e\u306e\u8178\u5185\u7d30\u83cc\u304c\u9ad8\u78ba\u7387\u3067\u5b58\u5728\u3059\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u4e2d\u306e1\u3064\u3067\u3042\u308b\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u83cc\u306f\u5927\u8178\u306e\u4e0a\u76ae\u306b\u7a74\u3092\u958b\u3051\u8178\u7ba1\u30d0\u30ea\u30a2\u3092\u7834\u58ca\u3057\u3001\u8178\u7ba1\u306e\u5916\u306b\u3042\u308b\u30ea\u30f3\u30d1\u7bc0\u306b\u79fb\u884c\u3057\u809d\u81d3\u5185\u306e\u904e\u5270\u306a\u514d\u75ab\u5fdc\u7b54\u3092\u8a98\u5c0e\u3059\u308b\u3053\u3068\u3092\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u793a\u3059\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\uff08\u56f31\uff09\u3002\u3055\u3089\u306b\u3001\u540c\u30de\u30a6\u30b9\u809d\u81d3\u3067\u8d77\u3053\u308bTH17\u514d\u75ab\u53cd\u5fdc\u306f\u3001\u6297\u83cc\u85ac\u306b\u3088\u308b\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u83cc\u306e\u6392\u9664\u306b\u3088\u308a30%\u7a0b\u5ea6\u306b\u6e1b\u5f31\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u672c\u6210\u679c\u306f\u3001\u8178\u5185\u306e3\u83cc\u304c\u809d\u81d3\u306e\u708e\u75c7\u3092\u8d77\u3053\u3059\u539f\u56e0\u3067\u3042\u308b\u53ef\u80fd\u6027\u3068\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u793a\u3057\u305f\u3082\u306e\u3067\u3001\u8178\u5185\u7d30\u83cc\u3092\u6a19\u7684\u3068\u3057\u305fPSC\u306b\u5bfe\u3059\u308b\u65b0\u305f\u306a\u6cbb\u7642\u85ac\u3084\u8a3a\u65ad\u85ac\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u30012019\u5e741\u670814\u65e5\uff08\u30b0\u30ea\u30cb\u30c3\u30b8\u6a19\u6e96\u6642\uff09\u306b\u56fd\u969b\u5b66\u8853\u96d1\u8a8c<a href=\"https:\/\/www.nature.com\/articles\/s41564-018-0333-1?WT.feed_name=subjects_bacteria\" target=\"_blank\" rel=\"noopener\">\u300eNature Microbiology\u300f\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u7248<\/a>\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_63218\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-63218\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig1-610x293.png\" alt=\"\" width=\"610\" height=\"293\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig1-610x293.png 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig1-768x368.png 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig1.png 1734w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\">\u3010\u56f31\u3011\u6210\u679c\u6982\u8981<\/p><\/div>\n<h4>\uff11\uff0e\u7814\u7a76\u306e\u80cc\u666f<\/h4>\n<p>\u539f\u767a\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\uff08PSC\uff09\u306f\u3001\u809d\u81d3\u5185\u5916\u306b\u5b58\u5728\u3059\u308b\u80c6\u6c41\u306e\u6d41\u308c\u9053\u3067\u3042\u308b\u80c6\u7ba1\u306b\u708e\u75c7\u304c\u8d77\u3053\u308a\u3001\u6570\u5e74\u304b\u3089\u6570\u5341\u5e74\u306e\u7d4c\u904e\u306b\u3088\u308a\u80c6\u7ba1\u72ed\u7a84\u3068\u305d\u308c\u306b\u4f34\u3046\u80c6\u6c41\u3046\u3063\u6ede\u3092\u751f\u3058\u308b\u539f\u56e0\u4e0d\u660e\u306e\u81ea\u5df1\u514d\u75ab\u6027\u75be\u60a3\u3067\u3059\u3002\u6700\u7d42\u7684\u306b\u306f\u809d\u786c\u5909\u3078\u9032\u5c55\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u56fd\u306e\u6307\u5b9a\u96e3\u75c5\uff08\u7279\u5b9a\u75be\u60a3\uff09\u306b\u8a8d\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u56fd\u5185\u306e\u63a8\u8a08\u60a3\u8005\u6570\u306f\u7d042,300\u540d\u3067\uff08\u96e3\u6cbb\u6027\u306e\u809d\u30fb\u80c6\u9053\u75be\u60a3\u306b\u95a2\u3059\u308b\u8abf\u67fb\u7814\u7a76\u73ed\u306e\u75ab\u5b66\u8abf\u67fb2007\u5e74\u5ea6\u30012015\u5e74\u5ea6\uff09\u3001\u4eca\u5f8c\u60a3\u8005\u6570\u306e\u5897\u52a0\u304c\u4e88\u60f3\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u75c5\u56e0\u3068\u3057\u3066\u591a\u304f\u306e\u907a\u4f1d\u7684\u8981\u56e0\u3001\u74b0\u5883\u7684\u8981\u56e0\u306e\u95a2\u4e0e\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u75c5\u614b\u306e\u89e3\u660e\u306b\u306f\u81f3\u3063\u3066\u304a\u3089\u305a\u3001\u809d\u79fb\u690d\u4ee5\u5916\u306b\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u5b58\u5728\u3057\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u75be\u60a3\u306f\u708e\u75c7\u6027\u8178\u75be\u60a3\u3092\u5408\u4f75\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u95a2\u9023\u304c\u793a\u5506\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u8178\u7ba1\u306b\u708e\u75c7\u304c\u8d77\u3053\u308b\u3068\u8178\u7ba1\u30d0\u30ea\u30a2\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u305d\u306e\u7d50\u679c\u3001\u8178\u5185\u7d30\u83cc\u3084\u305d\u306e\u4ee3\u8b1d\u7523\u7269\u304c\u8178\u7ba1\u3092\u51fa\u3066\u80c6\u7ba1\u3084\u8840\u7ba1\u306b\u4fb5\u5165\u3057\u307e\u3059\u3002\u3053\u308c\u304c\u809d\u81d3\u306b\u5230\u9054\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u672c\u75be\u60a3\u306e\u767a\u75c7\u3084\u75c5\u614b\u306e\u9032\u5c55\u306b\u81f3\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u8a73\u7d30\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<p>\u305d\u3053\u3067\u3001\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u8178\u5185\u7d30\u83cc\u3068\u3053\u306e\u75c5\u6c17\u306e\u76f4\u63a5\u7684\u306a\u95a2\u4fc2\u6027\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u306b\u3001\u60a3\u8005\u304b\u3089\u63d0\u4f9b\u3055\u308c\u305f\u7cde\u4fbf\u5fae\u751f\u7269\u30b5\u30f3\u30d7\u30eb\u3092\u7121\u83cc\u30de\u30a6\u30b9\uff08\u6ce82\uff09\u306b\u6295\u4e0e\u3057\u3001\u60a3\u8005\u306e\u8178\u5185\u74b0\u5883\u3092\u518d\u73fe\u3057\u305f\u300c\u30d2\u30c8\u30d5\u30ed\u30fc\u30e9\u5316\u30de\u30a6\u30b9\u300d\u3092\u7528\u3044\u3066\u7814\u7a76\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n<h4>\uff12\uff0e\u7814\u7a76\u306e\u6210\u679c<\/h4>\n<p>\u307e\u305a\u3001\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\uff08\u6ce83\uff09\u306b\u3088\u308a\u3001PSC\u60a3\u8005\u306e\u4fbf\u3092\u7121\u83cc\u30de\u30a6\u30b9\u306b\u7d4c\u53e3\u6295\u4e0e\u3057\u305f\u300c\u30d2\u30c8\u30d5\u30ed\u30fc\u30e9\u5316\u30de\u30a6\u30b9\u300d\u306e\u5927\u8178\u3084\u809d\u81d3\u306b\u5b58\u5728\u3059\u308b\u514d\u75ab\u7d30\u80de\u306e\u7a2e\u985e\u3092\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u8178\u5185\u7d30\u83cc\u304c\u8178\u7ba1\u5916\u81d3\u5668\u3067\u3042\u308b\u809d\u81d3\u306e\u514d\u75ab\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u89e3\u6790\u306e\u7d50\u679c\u3001\u809d\u81d3\u306b\u304a\u3044\u3066\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f317\uff08IL-17\uff09\u3092\u7523\u751f\u3059\u308bCD4 \u967d\u6027\u30d8\u30eb\u30d1\u30fcT\uff08TH17\uff09\u7d30\u80de\u304c\u9855\u8457\u306b\u5897\u52a0\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u73fe\u8c61\u306f\u7121\u83cc\u30de\u30a6\u30b9\u3084\u3001\u5065\u5e38\u4eba\u3084\u708e\u75c7\u6027\u8178\u75be\u60a3\u306e\u4e00\u3064\u3067\u3042\u308b\u6f70\u760d\u6027\u5927\u8178\u708e\u60a3\u8005\u306e\u4fbf\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u3067\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001PSC\u306b\u7279\u6709\u306e\u73fe\u8c61\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>PSC\u60a3\u8005\u306e\u4fbf\u4e2d\u306b\u8178\u7ba1\u306e\u5916\u306b\u79fb\u884c\u3057\u809d\u81d3\u306e\u514d\u75ab\u5fdc\u7b54\u3092\u8a98\u5c0e\u3059\u308b\u8178\u5185\u7d30\u83cc\u304c\u3042\u308b\u3068\u8003\u3048\u3001\u813e\u81d3\u3001\u809d\u81d3\u3001\u30ea\u30f3\u30d1\u7bc0\u306a\u3069\u306e\u81d3\u5668\u306b\u304a\u3044\u3066\u3053\u306e\u83cc\u306e\u5206\u96e2\u57f9\u990a\u3092\u8a66\u307f\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u8178\u5185\u7d30\u83cc\u3084\u305d\u306e\u4ee3\u8b1d\u7523\u7269\u306e\u5168\u8eab\u3078\u306e\u79fb\u52d5\u306e\u95a2\u6240\u3067\u3042\u308b\u8178\u9593\u819c\u30ea\u30f3\u30d1\u7bc0\u306b\u304a\u3044\u3066\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u5c5e\u306e\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u30fb\u30cb\u30e5\u30fc\u30e2\u30cb\u30a8\uff08<em>Klebsiella pneumoniae<\/em>\uff09\uff08\u6ce84\uff09\u3001\u30d7\u30ed\u30c6\u30a6\u30b9\u5c5e\u306e\u30d7\u30ed\u30c6\u30a6\u30b9\u30fb\u30df\u30e9\u30d3\u30ea\u30b9\uff08<em>Proteus mirabilis<\/em>\uff09\u3001\u30a8\u30f3\u30c6\u30ed\u30b3\u30c3\u30ab\u30b9\u5c5e\u306e\u30a8\u30f3\u30c6\u30ed\u30b3\u30c3\u30ab\u30b9\u30fb\u30ac\u30ea\u30ca\u30eb\u30e0\uff08<em>Enterococcus gallinarum<\/em>\uff09\u306e3\u3064\u306e\u83cc\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u3053\u306e3\u83cc\u306f\u3044\u305a\u308c\u3082PSC\u60a3\u8005\u306e\u4fbf\u4e2d\u306b\u9ad8\u3044\u983b\u5ea6\u3067\u5b58\u5728\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u30fb\u30cb\u30e5\u30fc\u30e2\u30cb\u30a8\u306f18\u540d\u306e\u60a3\u8005\u306e\u3046\u306117\u540d\u3067\u691c\u51fa\u3055\u308c\u3001\u5065\u5e38\u8005\u3001\u6f70\u760d\u6027\u5927\u8178\u708e\u3001\u4ed6\u306e\u81ea\u5df1\u514d\u75ab\u6027\u809d\u75be\u60a3\u306e\u60a3\u8005\u3068\u6bd4\u3079\u3066\u975e\u5e38\u306b\u9ad8\u7387\u3067\u3057\u305f\uff08\u56f32\uff09\u3002\u3053\u306e\u7d50\u679c\u306f\u6d77\u5916\u306e\u60a3\u8005\u30b5\u30f3\u30d7\u30eb\u3092\u7528\u3044\u305f\u89e3\u6790\u3067\u3082\u540c\u69d8\u3067\u3042\u308a\u3001\u4eba\u7a2e\u3092\u8d85\u3048\u305f\u666e\u904d\u7684\u306a\u73fe\u8c61\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_63213\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-63213\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig2-610x267.png\" alt=\"\" width=\"610\" height=\"267\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig2-610x267.png 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig2-768x337.png 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig2.png 826w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\">\u3010\u56f32\u3011\u4fbf\u30b5\u30f3\u30d7\u30eb1g\u3042\u305f\u308a\u306e\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u30fb\u30cb\u30e5\u30fc\u30e2\u30cb\u30a8\u306e\u83cc\u91cf<\/p><\/div>\n<p style=\"text-align: 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id=\"attachment_63220\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-63220\" src=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig3-610x467.png\" alt=\"\" width=\"610\" height=\"467\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig3-610x467.png 610w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig3-768x587.png 768w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2019\/01\/20190122_fig3.png 995w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\">\u3010\u56f33\u3011PSC\u60a3\u8005\u7531\u6765\u306e\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u83cc\u306f\u5927\u8178\u4e0a\u76ae\u57f9\u990a\u7d30\u80de\u306b\u7a74\u3092\u3042\u3051\u308b<\/p><\/div>\n<p style=\"text-align: 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16K09374\u300115H02534\u306b\u63a1\u629e\u3055\u308c\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n<h4>\uff15\uff0e\u8ad6\u6587\u60c5\u5831<\/h4>\n<ul>\n<li>\u82f1\u6587\u30bf\u30a4\u30c8\u30eb\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41564-018-0333-1?WT.feed_name=subjects_bacteria\" target=\"_blank\" rel=\"noopener\">Gut pathobionts underlie intestinal barrier dysfunction and liver Th17 immune response in primary sclerosing cholangitis<\/a><\/li>\n<li>\u30bf\u30a4\u30c8\u30eb\u548c\u8a33\uff1a\u539f\u767a\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u306b\u304a\u3044\u3066\u8178\u5185\u7d30\u83cc\u304c\u8178\u7ba1\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u4e0d\u5168\u3068\u809d\u81d3\u306eTh17\u5fdc\u7b54\u3092\u898f\u5b9a\u3059\u308b<\/li>\n<li>\u8457\u8005\u540d\uff1a\u4e2d\u672c\u4f38\u5b8f\u3001\u4f50\u3005\u6728\u4f38\u96c4\u3001\u9752\u6728\u4eae\u3001\u5bae\u672c\u5065\u592a\u90ce\u3001\u9808\u7530\u4e99\u3001\u5bfa\u8c37\u4fca\u662d\u3001\u9234\u6728\u8cb4\u535a\u3001\u5e78\u7530\u88d5\u9020\u3001\u891a\u67cf\u677e\u3001\u8c37\u6728\u4fe1\u4ec1\u3001\u5c71\u53e3\u6643\u5f18\u3001\u91d1\u68ee\u5149\u535a\u3001\u938c\u7530\u4fe1\u5f66\u3001\u670d\u90e8\u6b63\u5e73\u3001\u82a6\u7530\u6d69\u3001\u5742\u5143\u4ea8\u5b87\u3001\u65b0\u5e78\u4e8c\u3001\u6210\u5cf6\u8056\u5b50\u3001\u5409\u6751\u662d\u5f66\u3001\u672c\u7530\u8ce2\u4e5f\u3001\u4f50\u85e4\u4fca\u6717\u3001\u91d1\u4e95\u9686\u5178<\/li>\n<li>\u63b2\u8f09\u8a8c\uff1aNature Microbiology<\/li>\n<\/ul>\n<h5>\u7528\u8a9e\u89e3\u8aac<\/h5>\n<ul>\n<li>\uff08\u6ce81\uff09TH17\u7d30\u80de\uff1aCD4\u967d\u6027\u306e\u30d8\u30eb\u30d1\u30fcT \u7d30\u80de\u306e\u4e00\u7a2e\u3067\u3001\u4e3b\u306b\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3\uff08IL\uff09-17\u3092\u7523\u751f\u3059\u308b\u3002IL-17\u306f\u75c5\u539f\u4f53\u304b\u3089\u8eab\u3092\u5b88\u308b\u305f\u3081\u306e\u611f\u67d3\u9632\u5fa1\u306b\u91cd\u8981\u306a\u3060\u3051\u3067\u306a\u304f\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3084\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3067\u898b\u3089\u308c\u308b\u904e\u5270\u306a\u514d\u75ab\u5fdc\u7b54\u306b\u3088\u3063\u3066\u767a\u75c7\u3059\u308b\u75be\u75c5\u306b\u3082\u95a2\u308f\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u611f\u67d3\u3078\u306e\u9632\u5fa1\u6a5f\u80fd\u3092\u4fdd\u3061\u3064\u3064\u708e\u75c7\u3092\u56de\u907f\u3059\u308b\u306b\u306fTH17\u7d30\u80de\u306e\u9069\u5207\u306a\u5236\u5fa1\u304c\u5fc5\u8981\u3002<\/li>\n<li>\uff08\u6ce82\uff09 \u7121\u83cc\u30de\u30a6\u30b9\uff1a\u7121\u83cc\u72b6\u614b\u3092\u4fdd\u3064\u3053\u3068\u304c\u53ef\u80fd\u306a\u7279\u6b8a\u306a\u74b0\u5883\uff08\u30a2\u30a4\u30bd\u30ec\u30fc\u30bf\u30fc\uff09\u5185\u3067\u98fc\u80b2\u3057\u305f\u30de\u30a6\u30b9\u3067\u3001\u8178\u5185\u7d30\u83cc\u3084\u76ae\u819a\u306a\u3069\u306e\u5e38\u5728\u7d30\u83cc\u3092\u542b\u3081\u3001\u691c\u51fa\u53ef\u80fd\u306a\u5fae\u751f\u7269\u3092\u307e\u3063\u305f\u304f\u6301\u305f\u306a\u3044\u3002\u5e38\u5728\u7d30\u83cc\u3092\u6301\u305f\u306a\u3044\u305f\u3081\u3001\u751f\u7406\u5b66\u7684\u3001\u514d\u75ab\u5b66\u7684\u306b\u3044\u304f\u3064\u304b\u306e\u7570\u5e38\u304c\u307f\u3089\u308c\u308b\u304c\u3001\u5065\u5eb7\u306a\u72b6\u614b\u3092\u7dad\u6301\u3057\u3066\u3044\u308b\u3002<\/li>\n<li>\uff08\u6ce83\uff09\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\uff1a\u4e00\u3064\u306e\u7d30\u80de\u306e\u8907\u6570\u306e\u5206\u5b50\uff08\u4e3b\u306b\u30bf\u30f3\u30cf\u309a\u30af\u8cea\uff09\u3092\u540c\u6642\u304b\u3064\u9ad8\u901f\u306b\u6e2c\u5b9a\u3057\u3001\u8907\u6570\u7a2e\u985e\u306e\u7d30\u80de\u306e\u5206\u5e03\u3092\u89e3\u6790\u3059\u308b\u88c5\u7f6e\u3002\u7d30\u80de\u8868\u9762\u307e\u305f\u306f\u5185\u90e8\u306e\u5206\u5b50\u3092\u86cd\u5149\u7269\u8cea\u3067\u6a19\u8b58\u3057\u305f\u5f8c\u3001\u7d30\u80de\u4e00\u3064\u305a\u3064\u306b\u4e00\u5b9a\u6ce2\u9577\u306e\u30ec\u30fc\u30b6\u30fc\u5149\u3092\u5f53\u3066\u305f\u6642\u306b\u751f\u3058\u308b\u86cd\u5149\u6ce2\u9577\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u305d\u306e\u7d30\u80de\u304c\u4f55\u306e\u5206\u5b50\u3092\u6301\u3063\u3066\u3044\u308b\u304b\u3092\u5206\u6790\u3059\u308b\u3002\u3042\u308b\u90e8\u4f4d\u306b\u5b58\u5728\u3059\u308b\u7d30\u80de\u96c6\u56e3\u306e\u5897\u6e1b\u3084\u6a5f\u80fd\u5206\u5b50\u306e\u767a\u73fe\u91cf\u306e\u5897\u6e1b\u3092\u89e3\u6790\u3059\u308b\u305f\u3081\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u3002<\/li>\n<li>\uff08\u6ce84\uff09\u30af\u30ec\u30d6\u30b7\u30a8\u30e9\u30fb\u30cb\u30e5\u30fc\u30e2\u30cb\u30a8\uff08<em>Klebsiella pneumoniae<\/em><em>\uff09<\/em>\uff1a\u30d2\u30c8\u306e\u53e3\u8154\u3084\u8178\u5185\u306b\u5e38\u5728\u3057\u3066\u3044\u308b\u304b\u3099\u3001\u901a\u5e38\u306f\u75c5\u7684\u72b6\u614b\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u306f\u306a\u3044\u3002\u3057\u304b\u3057\u3001\u514d\u75ab\u7cfb\u304c\u5f31\u3063\u3066\u3044\u308b\u4eba\u3084\u9ad8\u9f62\u8005\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u306a\u3069\u3067\u306f\u3001\u80ba\u708e\u3084\u6c17\u7ba1\u652f\u708e\u3001\u8180\u80f1\u708e\u306a\u3069\u306e\u65e5\u548c\u898b\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b\u3002 \u80ba\u708e\u687f\u83cc\u3068\u3082\u547c\u3070\u308c\u308b\u3002<\/li>\n<li>\uff08\u6ce85\uff09\u30aa\u30eb\u30ac\u30ce\u30a4\u30c9\u57f9\u990a\u6280\u8853\uff1a\u5f93\u6765\u306e\u7d30\u80de\u57f9\u990a\u6280\u8853\u3067\u306f\u3001\u591a\u304f\u306e\u7d30\u80de\u306f\u30b7\u30fc\u30c8\u72b6\u306b\u57f9\u990a\u3055\u308c\u3066\u3044\u308b\u3002\u30aa\u30eb\u30ac\u30ce\u30a4\u30c9\u306f\u7d30\u80de\u306e\u5897\u6b96\u306e\u8db3\u5834\u3068\u306a\u308b\u30b8\u30a7\u30eb\u3068\u5897\u6b96\u56e0\u5b50\u3068\u547c\u3070\u308c\u308b\u6804\u990a\u306b\u3088\u308a\u30013 \u6b21\u5143\u69cb\u9020\u3068\u3057\u3066\u80b2\u3066\u3089\u308c\u305f\u57f9\u990a\u7d30\u80de\u3092\u6307\u3059\u30021\u3064\u306e\u5e79\u7d30\u80de\u304b\u3089\u751f\u4f53\u5185\u306e\u7d44\u7e54\u306b\u4f3c\u305f\u69cb\u9020\u3092\u57f9\u990a\u76bf\u306e\u4e2d\u3067\u4f5c\u308a\u51fa\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308a\u3001\u80c3\u3001\u5c0f\u8178\u3001\u5927\u8178\u3001\u81b5\u81d3\u3001\u809d\u81d3\u306a\u3069\u306e\u69d8\u3005\u306a\u7d44\u7e54\u306e\u6b63\u5e38\u306a\u7d30\u80de\u304a\u3088\u3073\u304c\u3093\u5e79\u7d30\u80de\u3092\u7121\u9650\u306b\u5897\u3084\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308b\u3002<\/li>\n<li>\uff08\u6ce86\uff09\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff1a\u591a\u7d30\u80de\u751f\u7269\u306e\u4f53\u3092\u69cb\u6210\u3059\u308b\u7d30\u80de\u306e\u6b7b\u306b\u65b9\u306e\u4e00\u7a2e\u3067\u3001\u7ba1\u7406\u30fb\u8abf\u7bc0\u3055\u308c\u305f\u7d30\u80de\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u3055\u308c\u305f\u7d30\u80de\u6b7b\u3092\u6307\u3059\u3002<\/li>\n<li>\uff08\u6ce87\uff09ROR-gt\uff1aTH17\u7d30\u80de\u3078\u306e\u5206\u5316\u3092\u8a98\u5c0e\u3055\u305b\u308b<a href=\"https:\/\/ja.wikipedia.org\/wiki\/%E8%BB%A2%E5%86%99%E5%9B%A0%E5%AD%90\">\u8ee2\u5199\u56e0\u5b50<\/a>\u3067\u3042\u308a\u3001IL-23\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u3092\u4ecb\u3057\u3066IL-17\u306e\u7523\u751f\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u8178\u5185\u7d30\u83cc\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85 \u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u306e\u670d\u90e8\u6b63\u5e73\uff08\u306f\u3063\u3068\u308a\u307e\u3055\u3072\u3089\uff09\u6559\u6388\u306f\u3001\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u7b49\u3068\u5171\u540c\u3067\u3001\u809d\u79fb\u690d\u4ee5\u5916\u306b\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u5c11\u306a\u3044\u96e3\u6cbb\u6027\u81ea\u5df1\u514d\u75ab\u6027\u75be\u60a3\u3067\u3042\u308b\u539f\u767a\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\uff08PSC\uff09\u60a3\u8005\u306e [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":63228,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[357,5],"class_list":["post-63209","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/63209","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=63209"}],"version-history":[{"count":0,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/63209\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/63228"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=63209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=63209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=63209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}