{"id":6310,"date":"2012-05-11T00:00:00","date_gmt":"2012-05-10T15:00:00","guid":{"rendered":"http:\/\/www.waseda.jp\/news\/6310"},"modified":"2014-10-30T12:10:52","modified_gmt":"2014-10-30T03:10:52","slug":"%e7%94%9f%e3%81%8d%e3%81%9f%e3%83%9e%e3%82%a6%e3%82%b9%e3%81%ae%e4%bd%93%e5%86%85%e6%99%82%e8%a8%88%e3%82%92%e6%ad%a3%e7%a2%ba%e3%81%ab%e6%b8%ac%e3%82%8b%e6%96%b9%e6%b3%95%e3%82%92%e9%96%8b%e7%99%ba","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/6310","title":{"rendered":"\u751f\u304d\u305f\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u6b63\u78ba\u306b\u6e2c\u308b\u65b9\u6cd5\u3092\u958b\u767a \u7406\u5de5\u30fb\u67f4\u7530\u91cd\u4fe1\u7814\u7a76\u5ba4\u3001\u8133\u5185\u306b\u4f53\u5185\u6642\u8a08\u306e\u4e2d\u67a2\u304c\u3042\u308b\u4e8b\u3082\u8a3c\u660e"},"content":{"rendered":"<p>\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u306e\u67f4\u7530\u91cd\u4fe1\u6559\u6388\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u4e16\u754c\u3067\u521d\u3081\u3066\uff11\u500b\u4f53\u306e\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u751f\u304d\u305f\u72b6\u614b\u3067\u6e2c\u5b9a\u3059\u308b\u65b9\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u5730\u7403\u306e\u81ea\u8ee2\u306b\u5408\u308f\u305b\u3066\u7d0424\u6642\u9593\u306e\u5468\u671f\u3067\u632f\u52d5\u3059\u308b\u6642\u8a08\u907a\u4f1d\u5b50\u306f\u4f53\u306e\u4e2d\u306e\u3042\u3089\u3086\u308b\u7d30\u80de\u3067\u767a\u73fe\u3057\u3066\u304a\u308a\u3001\u69d8\u3005\u306a\u751f\u7406\u73fe\u8c61\u306b\u300c\u663c\u30fb\u591c\u300d\u3068\u3044\u3046\u60c5\u5831\u3092\u4f1d\u3048\u308b\u91cd\u8981\u306a\u30b7\u30b9\u30c6\u30e0\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u5b9f\u969b\u306e\u751f\u4f53\u5185\u3067\u306f\u7d44\u7e54\u3084\u81d3\u5668\u306e\u6642\u8a08\u306e\u6642\u9593\u5408\u308f\u305b\u306e\u80fd\u529b\u304c\u3069\u308c\u304f\u3089\u3044\u6a5f\u80fd\u3057\u3066\u3044\u308b\u306e\u304b\u306f\u7591\u554f\u3067\u3057\u305f\u3002\u540c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u6642\u8a08\u907a\u4f1d\u5b50\u306e\u4e0b\u6d41\u306b\u30db\u30bf\u30eb\u30eb\u30b7\u30d5\u30a7\u30e9\u30fc\u30bc\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u305f\u30de\u30a6\u30b9(PER2::LUC\u30de\u30a6\u30b9)\u3068\u9ad8\u611f\u5ea6EMCCD\u30ab\u30e1\u30e9\u3092\u642d\u8f09\u3057\u305fin vivo imaging\u88c5\u7f6e<small>\uff08IVIS\u00ae Kinetic\u3001Caliper\u793e\uff09<\/small>\u3092\u7528\u3044\u3066\u3001\uff11\u500b\u4f53\u306e\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u751f\u304d\u305f\u72b6\u614b\u3067\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u30de\u30a6\u30b9\u306e\u672b\u68a2\u7d44\u7e54\u306e\u4f53\u5185\u6642\u8a08\u3092\u8133\u5185\u306b\u3042\u308b\u8996\u4ea4\u53c9\u4e0a\u6838\u3068\u547c\u3070\u308c\u308b\u5c0f\u3055\u306a\u795e\u7d4c\u6838\u304c\u5236\u5fa1\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u306a\u304a\u3001\u3053\u306e\u6210\u679c\u306b\u3064\u3044\u3066\u306fCurrent Biology\u8a8c\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div>\n<section>\n<h3>1.\u7814\u7a76\u306e\u80cc\u666f<\/h3>\n<div>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-9760\" alt=\"120511_mouse1\" src=\"http:\/\/www.waseda.jp\/top\/assets\/uploads\/2012\/05\/120511_mouse1.jpg\" width=\"480\" height=\"323\" \/><\/p>\n<\/div>\n<p>\u5730\u7403\u4e0a\u306e\u751f\u7269\u306f\u5730\u7403\u306e\u81ea\u8ee2\u306b\u5408\u308f\u305b\u3066\uff12\uff14\u6642\u9593\u306e\u751f\u6d3b\u30ea\u30ba\u30e0\u3092\u523b\u3093\u3067\u304a\u308a\u3001\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u3057\u3066\u7d04\uff12\uff14\u6642\u9593\u306e\u5468\u671f\u3067\u632f\u52d5\u3059\u308b\u6642\u8a08\u907a\u4f1d\u5b50\u306e\u5b58\u5728\u304c\u8fd1\u5e74\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u6642\u8a08\u907a\u4f1d\u5b50<small>\uff08Per2, Bmal1\uff09<\/small>\u306f\u4f53\u306e\u4e2d\u306e\u3042\u3089\u3086\u308b\u7d30\u80de\u3067\u767a\u73fe\u3057\u3066\u304a\u308a\u3001\u69d8\u3005\u306a\u751f\u7406\u73fe\u8c61\u306b\u300c\u663c\u30fb\u591c\u300d\u3068\u3044\u3046\u60c5\u5831\u3092\u4f1d\u3048\u308b\u91cd\u8981\u306a\u30b7\u30b9\u30c6\u30e0\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u6211\u3005\u54fa\u4e73\u985e\u306e\u4f53\u5185\u6642\u8a08\u306f\u3001\u8133\u306b\u3042\u308b\u8996\u4ea4\u53c9\u4e0a\u6838\u3068\u547c\u3070\u308c\u308b\u5c0f\u3055\u306a\u795e\u7d4c\u6838\u304c\u4e3b\u6642\u8a08\u3068\u3057\u3066\u4f53\u306e\u81d3\u5668\u3084\u7d44\u7e54\u306e\u672b\u68a2\u6642\u8a08\u3092\u8abf\u7bc0\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3068\u3053\u308d\u3067\u57f9\u990a\u3057\u305f\u7d44\u7e54\u3084\u7d30\u80de\u3092\u7528\u3044\u305f\u7814\u7a76\u306b\u3088\u308a\u3001\u4f53\u5916\u3067\u57f9\u990a\u3057\u3066\u3044\u308b\u7d30\u80de\u3082\u72ec\u81ea\u306b\u6642\u9593\u3092\u5408\u308f\u305b\u308b\u80fd\u529b\u304c\u3042\u308b\u4e8b\u304c\u8fd1\u5e74\u5206\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u5b9f\u969b\u306e\u751f\u4f53\u5185\u3067\u306f\u7d44\u7e54\u3084\u81d3\u5668\u306e\u6642\u8a08\u306e\u6642\u9593\u5408\u308f\u305b\u306e\u80fd\u529b\u304c\u3069\u308c\u304f\u3089\u3044\u6a5f\u80fd\u3057\u3066\u3044\u308b\u306e\u304b\u306f\u7591\u554f\u3067\u3057\u305f\u3002<\/p>\n<p>\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u751f\u4f53\u5185<small>\uff08in vivo\uff09<\/small>\u3067\u306e\u4f53\u5185\u6642\u8a08\u7814\u7a76\u306f\u3001\u4e0a\u8ff0\u306e\u751f\u4f53\u5916<small>\uff08in vitro\uff09<\/small>\u3067\u306e\u7814\u7a76\u7d50\u679c\u3092\u767a\u5c55\u3055\u305b\u308b\u306e\u306b\u5fc5\u9808\u3067\u3042\u308a\u3001\u307e\u305f\u81d3\u5668\u9593\u306e\u6642\u8a08\u306e\u76f8\u4e92\u95a2\u4fc2\u3092\u8abf\u3079\u308b\u306e\u306b\u306f\u5fc5\u9808\u306e\u6280\u8853\u3067\u3042\u308a\u3001in vivo\u3067\u306e\u4f53\u5185\u6642\u8a08\u6e2c\u5b9a\u6cd5\u306e\u958b\u767a\u306f\u5f85\u3061\u671b\u307e\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u4eca\u56de\u6211\u3005\u306f\u3001\u6642\u8a08\u907a\u4f1d\u5b50\u306e\u4e0b\u6d41\u306b\u30db\u30bf\u30eb\u30eb\u30b7\u30d5\u30a7\u30e9\u30fc\u30bc\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u305f\u30de\u30a6\u30b9(PER2::LUC\u30de\u30a6\u30b9)\u3068\u9ad8\u611f\u5ea6EMCCD\u30ab\u30e1\u30e9\u3092\u642d\u8f09\u3057\u305fin vivo imaging\u88c5\u7f6e<small>\uff08IVIS\u00ae Kinetic\u3001Caliper\u793e\uff09<\/small>\u3092\u7528\u3044\u3066\u3001\u4e16\u754c\u3067\u521d\u3081\u3066\uff11\u500b\u4f53\u306e\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u751f\u304d\u305f\u72b6\u614b\u3067\u6e2c\u5b9a\u3059\u308b\u30e6\u30cb\u30fc\u30af\u306a\u65b9\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u65b9\u6cd5\u306f\u3068\u3066\u3082\u7c21\u4fbf\u3067\u3042\u308a\u3001\u307e\u305f\u5b9f\u9a13\u8aa4\u5dee\u304c\u5c11\u306a\u304f\u3001\u52d5\u7269\u502b\u7406\u7684\u306b\u3082\u512a\u308c\u305f\u65b9\u6cd5\u3067\u3059\u3002<small>\uff08\u7814\u7a76\u6982\u8981\u30a4\u30e1\u30fc\u30b8\u3001\u56f3\uff11\uff09<\/small><\/p>\n<h3>2.\u7814\u7a76\u624b\u6cd5\u3068\u6210\u679c<\/h3>\n<h4>(1)\u4f53\u5185\u6642\u8a08\u6e2c\u5b9a\u6cd5\u306e\u78ba\u7acb<\/h4>\n<div>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-9759\" alt=\"120511_mouse2\" src=\"http:\/\/www.waseda.jp\/top\/assets\/uploads\/2012\/05\/120511_mouse2.jpg\" width=\"480\" height=\"321\" \/><\/p>\n<\/div>\n<p>\u6642\u8a08\u907a\u4f1d\u5b50Per2\u306e\u4e0b\u6d41\u306b\u30db\u30bf\u30eb\u306e\u767a\u5149\u9175\u7d20\u3067\u3042\u308b\u30eb\u30b7\u30d5\u30a7\u30e9\u30fc\u30bc<small>\uff08Luciferase\uff09<\/small>\u3092\u5c0e\u5165\u3057\u305f\u30de\u30a6\u30b9\u306f\u3001PER2::LUCEFERASE\u3068\u3044\u3046\u8907\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u751f\u6210\u3057\u307e\u3059\u3002\u767a\u5149\u57fa\u8cea\u3067\u3042\u308b\u30eb\u30b7\u30d5\u30a7\u30ea\u30f3\u3092\u3053\u306e\u30de\u30a6\u30b9\u306b\u6295\u4e0e\u3059\u308b\u4e8b\u3067\u3001PER2::LUCIFERASE\u306e\u91cf\u306b\u76f8\u95a2\u3057\u305f\u751f\u7269\u767a\u5149\u304c\u5404\u81d3\u5668\u3067\u898b\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u767a\u5149\u306f\u3068\u3066\u3082\u5fae\u91cf\u3067\u3059\u304c\u3001\u6697\u95c7\u306e\u4e2d\u3067\u9ad8\u611f\u5ea6EMCCD\u30ab\u30e1\u30e9\u3092\u7528\u3044\u3066\u64ae\u5f71\u3059\u308b\u4e8b\u3067\u3001\u76ae\u819a\u304b\u3089\u900f\u904e\u3057\u305f\u5149\u3068\u3057\u3066\u81d3\u5668\u306e\u767a\u5149\u3092\u6e2c\u5b9a\u3059\u308b\u4e8b\u304c\u51fa\u6765\u307e\u3059<small>\uff08\u56f3\uff11\uff09<\/small>\u3002\u6211\u3005\u306f\u3001\u3053\u306e\u64ae\u5f71\u3092\uff14\u6642\u9593\u304a\u304d\u306b\uff12\uff14\u6642\u9593\u9023\u7d9a\u3067\u884c\u3046\u4e8b\u3067\u3001 \u56f3\uff12\u306e\u3088\u3046\u306a\u7dba\u9e97\u306a\u767a\u5149\u30ea\u30ba\u30e0\u3092\u5f97\u308b\u4e8b\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u3082\u3046\u4e00\u3064\u306e\u6642\u8a08\u907a\u4f1d\u5b50\u3067\u3042\u308bBmal1\u306f\u30ea\u30ba\u30e0\u306e\u30d4\u30fc\u30af\u6642\u523b\u304cPer2\u3068\u9006\u306e\u6642\u9593\u306b\u306a\u308b\u4e8b\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306eBmal1\u306b\u767a\u5149\u30b7\u30b9\u30c6\u30e0\u3092\u5c0e\u5165\u3057\u305f\u30de\u30a6\u30b9<small>\uff08Bmal1-ELuc\u30de\u30a6\u30b9\uff09<\/small>\u3067\u540c\u3058\u624b\u6cd5\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u767a\u5149\u30ea\u30ba\u30e0\u304c\u9006\u4f4d\u76f8\u306b\u306a\u308b\u4e8b\u3082\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<h4>(2)\u8996\u4ea4\u53c9\u4e0a\u6838\u3092\u7834\u58ca\u3057\u305f\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u6e2c\u5b9a<\/h4>\n<div>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-9758\" alt=\"120511_mouse3\" src=\"http:\/\/www.waseda.jp\/top\/assets\/uploads\/2012\/05\/120511_mouse3.jpg\" width=\"480\" height=\"424\" \/><\/p>\n<\/div>\n<p>\u4f53\u5185\u6642\u8a08\u306e\u4e2d\u67a2\u3068\u8003\u3048\u3089\u308c\u3066\u304d\u305f\u8996\u4ea4\u53c9\u4e0a\u6838\u3092\u71b1\u7834\u58ca\u3057\u305f\u30de\u30a6\u30b9\u306f\u3001\u884c\u52d5\u3001\u7761\u7720\u30fb\u899a\u9192\u30ea\u30ba\u30e0\u304c\u6d88\u5931\u3057\u307e\u3057\u305f\u3002\u6211\u3005\u306f\u305d\u306e\u30de\u30a6\u30b9\u306e\u672b\u68a2\u7d44\u7e54\u306e\u809d\u81d3\u30fb\u814e\u81d3\u30fb\u984e\u4e0b\u817a\u306e\u4f53\u5185\u6642\u8a08\u3092\u6e2c\u5b9a\u3057\u305f\u3068\u3053\u308d\u3001\u632f\u5e45\u304c\u6709\u610f\u306b\u6e1b\u5f31\u3057\u3066\u3044\u308b\u4e8b\u304b\u3089\u3001\u30de\u30a6\u30b9\u306e\u672b\u68a2\u7d44\u7e54\u306e\u4f53\u5185\u6642\u8a08\u3092\u8996\u4ea4\u53c9\u4e0a\u6838\u304c\u5236\u5fa1\u3057\u3066\u3044\u308b\u4e8b\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u7834\u58ca\u3057\u305f\u30de\u30a6\u30b9\u306e\u4e00\u90e8\u306f\u7834\u58ca\u4e00\u30f6\u6708\u5f8c\u3067\u3082\u3001\u6642\u8a08\u304c\u6b62\u307e\u308b\u3053\u3068\u306a\u304f\u3001\u632f\u5e45\u304c\u843d\u3061\u305f\u5c0f\u3055\u306a\u6642\u8a08\u3068\u3057\u3066\u7dad\u6301\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u6642\u8a08\u306e\u30ea\u30ba\u30e0\u5468\u671f<small>\uff08\u7d0423.7\u6642\u9593\uff09<\/small>\u306f\u81d3\u5668\u9593\u3067\u5dee\u7570\u304c\u7121\u304f\u3001\u6052\u6697\u6761\u4ef6\u4e0b\u3067\u306e\u884c\u52d5\u30ea\u30ba\u30e0\u306e\u5468\u671f\u3068\u540c\u3058\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u4e3b\u6642\u8a08\u3082\u672b\u68a2\u6642\u8a08\u3082\u4f3c\u305f\u5206\u5b50\u6a5f\u69cb\u3067\u6642\u8a08\u3092\u523b\u3093\u3067\u3044\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h3>3.\u4eca\u5f8c\u306e\u671f\u5f85<\/h3>\n<p>in vivo\u3067\u306e\u751f\u7269\u767a\u5149\u6e2c\u5b9a\u306f\u764c\u7814\u7a76\u3067\u8fd1\u5e74\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u3089\u308c\u3066\u304d\u3066\u3044\u307e\u3059\u304c\u3001\u307e\u3060\u624b\u6cd5\u3078\u306e\u7591\u554f\u70b9\u3082\u6b8b\u3063\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u6211\u3005\u306f\u3001\u591a\u304f\u306e\u57fa\u790e\u7684\u306a\u5b9f\u9a13\u7d50\u679c\u3068\u5171\u306b\u65b0\u3057\u304f\u4f53\u5185\u6642\u8a08\u3092\u6b63\u78ba\u306b\u7c21\u4fbf\u306b\u6e2c\u5b9a\u3059\u308b\u65b9\u6cd5\u3092\u78ba\u7acb\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u306e\u7814\u7a76\u8ab2\u984c\u3068\u3057\u3066\u751f\u4f53\u5185\u3067\u306e\u7814\u7a76\u306f\u5fc5\u9808\u9805\u76ee\u3067\u3042\u308a\u3001\u6211\u3005\u306e\u624b\u6cd5\u3092\u7528\u3044\u305f\u65b0\u3057\u3044\u767a\u898b\u3001\u307e\u305f\u4ed6\u306e\u5206\u91ce\u3067\u306e\u5fdc\u7528\u30fb\u767a\u5c55\u306b\u671f\u5f85\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u672b\u68a2\u7d44\u7e54\u306e\u4f53\u5185\u6642\u8a08\u306f\u4ee3\u8b1d\u3084\u514d\u75ab\u3084\u764c\u306e\u767a\u75c7\u306a\u3069\u591a\u304f\u306e\u91cd\u8981\u306a\u6a5f\u80fd\u306b\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u30ea\u30ba\u30e0\u969c\u5bb3\u8005<small>\uff08\u7761\u7720\u969c\u5bb3\u3084\u4ea4\u4ee3\u52e4\u52d9\u8005\uff09<\/small>\u306e\u4ee3\u8b1d\u3001\u514d\u75ab\u6a5f\u80fd\u306e\u60aa\u5316\u306f\u75ab\u5b66\u8abf\u67fb\u7b49\u3067\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u3001\u6211\u3005\u306f\u8133\u306b\u3042\u308b\u4e3b\u6642\u8a08\u304c\u50cd\u304b\u306a\u3044\u72b6\u614b\u3092\u7269\u7406\u7684\u306b\u4f5c\u308a\u51fa\u3059\u4e8b\u3067\u3001\u4f53\u5185\u6642\u8a08\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u306e\u7814\u7a76\u3068\u3057\u3066\u3001\u30ea\u30ba\u30e0\u969c\u5bb3\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u7528\u3044\u3001\u75be\u75c5\u3084\u85ac\u7269\u6cbb\u7642\u306b\u304a\u3051\u308b\u672b\u68a2\u4f53\u5185\u6642\u8a08\u306e\u5f79\u5272\u89e3\u660e\u306b\u4eca\u56de\u306e\u6280\u8853\u3092\u5fdc\u7528\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3>\u8ad6\u6587\u984c\u540d\u53ca\u3073\u8457\u8005<\/h3>\n<p>Current Biology\uff1aIn Vivo Monitoring of Peripheral Circadian Clocks in the Mouse<\/p>\n<p>\u7530\u539f\u3000\u512a\uff11\u3001\uff13\u3001\u9ed2\u7530\u3000\u5927\u6681\uff11\u3001\u9f4b\u85e4\u3000\u6075\u7950\uff11\u3001\u4e2d\u5cf6\u3000\u82b3\u6d69\uff12\u3001\u4e45\u4fdd\u3000\u7950\u4e8c\uff11\u3001\u5927\u897f\u3000\u4fe1\u660e\uff11\u3001\u702c\u5c3e\u3000\u6cf0\u88d5\uff11\u3001\u5927\u585a\u3000\u69d9\u5b50\uff11\u3001\u5e03\u65bd\u3000\u60a0\u592a\uff11\u3001\u5927\u6d66\u3000\u96c4\u7d00\uff11\u3001\u5c0f\u677e\u3000\u62d3\u77e2\uff11\u3001\u68ee\u8c37\u3000\u6d0b\u5e73\uff11\u3001\u5ca1\u7530\u3000\u6167\uff11\u3001\u53e4\u8c37\u3000\u76f4\u6a39\uff11\u3001\u5e73\u5c3e\u3000\u5f70\u5b50\uff11\u3001\u5800\u5ddd\u3000\u548c\u653f\uff11\u3001\u5de5\u85e4\u3000\u5d07\uff13\u3001\u67f4\u7530\u3000\u91cd\u4fe1\uff11<\/p>\n<p><small>\uff08\uff11\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u30fb\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1\u3001\uff12\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6240\u30fb\u5065\u5eb7\u5de5\u5b66\u7814\u7a76\u90e8\u9580\u30fb\u751f\u4f53\u6a5f\u80fd\u5236\u5fa1\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3001\uff13Department of Psychiatry and Biobehavioral Sciences, University of California-Los Angeles\uff09<\/small><\/p>\n<h4>\u30ea\u30f3\u30af<\/h4>\n<p><a href=\"http:\/\/www.cell.com\/current-biology\/abstract\/S0960-9822(12)00396-X\" target=\"_blank\">In Vivo Monitoring of Peripheral Circadian Clocks in the Mouse<\/a><\/p>\n<p><a href=\"http:\/\/www.waseda.jp\/sem-shibatas\/index.html\" target=\"_blank\">\u67f4\u7530\u91cd\u4fe1\u7814\u7a76\u5ba4<\/a><\/p>\n<p><a href=\"http:\/\/www.yomiuri.co.jp\/adv\/wol\/opinion\/earthquake_110620.htm\" target=\"_blank\">\u30ef\u30bb\u30c0\u30aa\u30f3\u30e9\u30a4\u30f3\uff1a\u30b5\u30de\u30fc\u30bf\u30a4\u30e0\u3068\u4f53\u5185\u6642\u8a08\u2015\u7bc0\u96fb\u306e\u590f\u3092\u4e57\u308a\u5207\u308b\u305f\u3081\u306b<\/a><\/p>\n<\/section>\n<div style=\"text-align: right;\">\u4ee5\u3000\u4e0a<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u306e\u67f4\u7530\u91cd\u4fe1\u6559\u6388\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u4e16\u754c\u3067\u521d\u3081\u3066\uff11\u500b\u4f53\u306e\u30de\u30a6\u30b9\u306e\u4f53\u5185\u6642\u8a08\u3092\u751f\u304d\u305f\u72b6\u614b\u3067\u6e2c\u5b9a\u3059\u308b\u65b9\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u5730\u7403\u306e\u81ea\u8ee2\u306b\u5408\u308f\u305b\u3066\u7d0424\u6642\u9593\u306e\u5468\u671f\u3067\u632f\u52d5\u3059\u308b\u6642\u8a08\u907a\u4f1d\u5b50\u306f\u4f53\u306e\u4e2d\u306e\u3042\u3089\u3086\u308b\u7d30\u80de\u3067\u767a\u73fe\u3057\u3066\u304a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":6566,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[53,186,5],"class_list":["post-6310","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-health","tag-tech","tag-research","lang-ja"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6310","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=6310"}],"version-history":[{"count":0,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6310\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/6566"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=6310"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=6310"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=6310"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}