{"id":50367,"date":"2017-04-24T09:43:59","date_gmt":"2017-04-24T00:43:59","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=50367"},"modified":"2018-10-11T12:02:52","modified_gmt":"2018-10-11T03:02:52","slug":"%e5%8c%bb%e5%ad%a6%e5%88%86%e9%87%8e%e3%81%ae%e9%87%8d%e8%a6%81%e8%aa%b2%e9%a1%8c%e3%81%a7%e3%81%82%e3%82%8b%e6%80%9d%e6%98%a5%e6%9c%9f%e7%99%ba%e6%9d%a5%e9%9a%9c%e5%ae%b3%e3%82%92%e5%b0%8e%e3%81%8f","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/50367","title":{"rendered":"\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u3092\u89e3\u660e"},"content":{"rendered":"

\u533b\u5b66\u5206\u91ce\u306e\u91cd\u8981\u8ab2\u984c\u3067\u3042\u308b\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u3092\u89e3\u660e
\n\u30d2\u30c8\u306e\u751f\u6b96\u53ef\u80fd\u3068\u306a\u308b\u91cd\u8981\u306a\u6642\u671f\u3067\u306e\u969c\u5bb3\u306b\u60a9\u3080\u591a\u304f\u306e\u60a3\u8005\u306e\u6cbb\u7642\u6cd5\u958b\u767a\u3078<\/h2>\n

\u65e9\u7a32\u7530\u5927\u5b66\u6559\u80b2\u30fb\u7dcf\u5408\u79d1\u5b66\u5b66\u8853\u9662<\/a>\/\u5148\u7aef\u751f\u547d\u533b\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc\uff08TWIns\uff09<\/a>\u306e\u6e05\u539f\u7f8e\u4f73\uff08\u304d\u3088\u306f\u3089 \u307f\u304b \u7b52\u4e95\u7814\u7a76\u5ba4\u306e\u7814\u7a76\u751f\u30fb\u6771\u4eac\u6148\u6075\u4f1a\u533b\u79d1\u5927\u5b66\u535a\u58eb\u8ab2\u7a0b\u9662\u751f\uff09\u3001\u5b6b\u30e6\u30ea\uff08\u305d\u3093 \u3086\u308a JSPS\u306b\u3088\u308b\u7b52\u4e95\u7814\u7a76\u5ba4\u306e\u7279\u5225\u7814\u7a76\u54e1\uff09\u3001\u7b52\u4e95\u548c\u7fa9\uff08\u3064\u3064\u3044 \u304b\u305a\u3088\u3057\uff09\u6559\u6388<\/a>\u306f\u3001\u533b\u5b66\u5206\u91ce\u306e\u91cd\u8981\u8ab2\u984c\u3067\u3042\u308b\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u601d\u6625\u671f\u306f\u30d2\u30c8\u306e\u751f\u6b96\u53ef\u80fd\u3068\u306a\u308b\u91cd\u8981\u306a\u6642\u671f\u3067\u3042\u308a\u3001\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u306e\u89e3\u660e\u306f\u533b\u5b66\u5206\u91ce\u306e\u91cd\u8981\u8ab2\u984c\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u306f\u3001\u3053\u308c\u307e\u3067\u4e0d\u660e\u306e\u307e\u307e\u3067\u3057\u305f\u30022000\u5e74\u306b\u7b52\u4e95\u6559\u6388\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u306e\u653e\u51fa\u3092\u6291\u5236\u3059\u308b\u65b0\u898f\u306e\u8133\u30db\u30eb\u30e2\u30f3\u3092\u767a\u898b\u3057\u3066\u3001\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u653e\u51fa\u6291\u5236\u30db\u30eb\u30e2\u30f3(GnIH)\u3068\u547d\u540d\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u306e\u7814\u7a76\u306b\u3088\u308a\u3001GnIH\u306f\u54fa\u4e73\u985e\u3084\u970a\u9577\u985e\u306e\u30d2\u30c8\u306b\u5b58\u5728\u3059\u308b\u3053\u3068\u3084\u3001GnIH\u306f\u54fa\u4e73\u985e\u3084\u30d2\u30c8\u306e\u751f\u6b96\u6a5f\u80fd\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306f\u601d\u6625\u671f\u767a\u6765\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u4ed5\u7d44\u306f\u4e0d\u660e\u3067\u3057\u305f\u3002<\/p>\n

\u672c\u7814\u7a76\u306b\u3088\u308a\u3001\u8133\u5185\u306eGnIH\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u306f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u53d7\u5bb9\u4f53\u304c\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u3084\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306fGnIH\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u4f5c\u7528\u3057\u3066GnIH\u306e\u767a\u73fe\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u4f4e\u4e0b\u306f\u3001GnIH\u907a\u4f1d\u5b50\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u3092\u5c0e\u304f\u3053\u3068\u3067GnIH\u767a\u73fe\u3092\u6709\u610f\u306b\u5897\u52a0\u3055\u305b\u3001\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306e\u4f4e\u4e0b\u3068\u601d\u6625\u671f\u767a\u6765\u306e\u9045\u767a\u3092\u8a98\u5c0e\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u672c\u7814\u7a76\u6210\u679c\u306b\u3088\u308a\u3001\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u306b\u6709\u52b9\u3068\u306a\u308b\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u306b\u60a9\u3080\u591a\u304f\u306e\u60a3\u8005\u306e\u6cbb\u7642\u306b\u5927\u304d\u304f\u8ca2\u732e\u3057\u307e\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u6210\u679c\u306e\u8ad6\u6587\u306eOnline \u7248\u304c\u3001\u82f1\u56fd\u306e\u79d1\u5b66\u8a8c\uff08\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u8a8c\uff09\u300eScientific Reports (Nature Publication Group)\u300f\u306b\u30014\u670821\u65e5\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u8ad6\u6587\u984c\u76ee\uff1aInvolvement of gonadotropin-inhibitory hormone in pubertal disorders induced\u00a0by thyroid status<\/a>
\n\u8457\u8005\uff1aMika Kiyohara, You Lee Son, Kazuyoshi Tsutsui
\nWaseda University<\/p>\n

(1) \u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/h4>\n

\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u306f\u3053\u308c\u307e\u3067\u4e0d\u660e\u3067\u3042\u3063\u305f\u30022000\u5e74\u306b\u7b52\u4e95\u6559\u6388\u3089\u306f\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u306e\u653e\u51fa\u3092\u6291\u5236\u3059\u308b\u65b0\u898f\u306e\u8133\u30db\u30eb\u30e2\u30f3\u3092\u767a\u898b\u3057\u3001\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u653e\u51fa\u6291\u5236\u30db\u30eb\u30e2\u30f3(GnIH)\u3068\u547d\u540d\u3057\u305f\u3002\u305d\u306e\u5f8c\u306e\u7814\u7a76\u306b\u3088\u308a\u3001GnIH\u306f\u54fa\u4e73\u985e\u3084\u970a\u9577\u985e\u306e\u30d2\u30c8\u306b\u5b58\u5728\u3059\u308b\u3053\u3068\u3084GnIH\u306f\u54fa\u4e73\u985e\u3084\u30d2\u30c8\u306e\u751f\u6b96\u6a5f\u80fd\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3002\u601d\u6625\u671f\u306f\u751f\u6b96\u304c\u53ef\u80fd\u3068\u306a\u308b\u91cd\u8981\u306a\u6642\u671f\u3067\u3042\u308b\u304c\u3001\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u306f\u30d2\u30c8\u3084\u591a\u304f\u306e\u54fa\u4e73\u985e\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u306f\u533b\u5b66\u306e\u5206\u91ce\u306e\u91cd\u8981\u8ab2\u984c\u3067\u3042\u308a\u3001\u3053\u308c\u307e\u3067\u306b\u591a\u304f\u306e\u7814\u7a76\u304c\u306a\u3055\u308c\u3066\u304a\u308a\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u304c\u601d\u6625\u671f\u767a\u6765\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3082\u77e5\u3089\u308c\u3066\u3044\u305f\u304c\u3001\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u306a\u304b\u3063\u305f\u3002<\/p>\n

(2) \u305d\u306e\u305f\u3081\u306b\u65b0\u3057\u304f\u958b\u767a\u3057\u305f\u624b\u6cd5<\/h4>\n

\u9ad8\u611f\u5ea6\u30da\u30d7\u30c1\u30c9\u5b9a\u91cf\u6cd5\u3001\u9ad8\u611f\u5ea6\u30db\u30eb\u30e2\u30f3\u5b9a\u91cf\u6cd5\u3001GnIH\u907a\u4f1d\u5b50\u306e\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u6cd5\u30fbRNA\u5e72\u6e09\u6cd5\u3001GnIH\u907a\u4f1d\u5b50\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u89e3\u6790\u6cd5\u3002<\/p>\n

(3) \u7814\u7a76\u306e\u7d50\u679c<\/h4>\n

\u7b52\u4e95\u6559\u6388\u304c\u767a\u898b\u3057\u305fGnIH\u306f\u54fa\u4e73\u985e\u3084\u30d2\u30c8\u306e\u751f\u6b96\u6a5f\u80fd\u3092\u6291\u5236\u3059\u308b\u65b0\u898f\u8133\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u3002\u672c\u7814\u7a76\u306b\u3088\u308a\u3001\u8133\u5185\u306eGnIH\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u306f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u53d7\u5bb9\u4f53\u304c\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u3084\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306fGnIH\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u4f5c\u7528\u3057\u3066GnIH\u306e\u767a\u73fe\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3002\u3055\u3089\u306b\u3001\u7532\u72b6\u817a\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u305f\u30de\u30a6\u30b9\u3092\u7528\u3044\u3001GnIH\u306e\u767a\u73fe\u3068\u601d\u6625\u671f\u306e\u767a\u6765\u3092\u89e3\u6790\u3057\u305f\u3068\u3053\u308d\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u4f4e\u4e0b\u306fGnIH\u907a\u4f1d\u5b50\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u3092\u5c0e\u304f\u3053\u3068\u3067GnIH\u767a\u73fe\u3092\u6709\u610f\u306b\u5897\u52a0\u3055\u305b\u3001\u751f\u6b96\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306e\u4f4e\u4e0b\u3068\u601d\u6625\u671f\u767a\u6765\u306e\u9045\u767a\u3092\u8a98\u5c0e\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u4ee5\u4e0a\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u304c\u4f4e\u4e0b\u3059\u308b\u3068GnIH \u767a\u73fe\u304c\u5897\u52a0\u3057\u3066\u601d\u6625\u671f\u767a\u6765\u304c\u9045\u5ef6\u3059\u308b\u3053\u3068\u304c\u767a\u898b\u3055\u308c\u305f\u3002<\/p>\n

(4) \u7814\u7a76\u306e\u5c55\u671b<\/h4>\n

\u601d\u6625\u671f\u767a\u6765\u306e\u969c\u5bb3\u306e\u8133\u5185\u6a5f\u69cb\u3092\u89e3\u660e\u3057\u305f\u672c\u7814\u7a76\u6210\u679c\u306b\u3088\u308a\u3001\u6709\u52b9\u3068\u306a\u308b\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u53ef\u80fd\u3068\u306a\u308b\u3002\u3053\u306e\u969c\u5bb3\u306b\u60a9\u3080\u591a\u304f\u306e\u60a3\u8005\u306e\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u308b\u672c\u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c\u3084\u793e\u4f1a\u7684\u5f71\u97ff\u306f\u5927\u304d\u3044\u3068\u601d\u308f\u308c\u308b\u3002\u6cbb\u7642\u6cd5\u3092\u958b\u767a\u3059\u308b\u5fdc\u7528\u7814\u7a76\u304c\u4eca\u5f8c\u306e\u8ab2\u984c\u3067\u3042\u308b\u3002<\/p>\n

\u8ad6\u6587\u60c5\u5831<\/h4>\n

\u63b2\u8f09\u8a8c\uff1a
\nScientific Reports (Nature Publication Group)<\/p>\n

\u8ad6\u6587\u984c\u76ee\uff1a
\nInvolvement of gonadotropin-inhibitory hormone in pubertal disorders induced by thyroid status<\/p>\n

\u8457\u8005\uff1a
\nMika Kiyohara\uff08\u6e05\u539f\u7f8e\u4f73\uff091,2<\/sup>\u3001You Lee Son\uff08\u5b6b\u30e6\u30ea\uff091<\/sup>\u3001Kazuyoshi Tsutsui\uff08\u7b52\u4e95\u548c\u7fa9\uff09\uff11<\/sup>
\n\uff08\uff11\u65e9\u7a32\u7530\u5927\u5b66 \u6559\u80b2\u30fb\u7dcf\u5408\u79d1\u5b66\u5b66\u8853\u9662\/\u5148\u7aef\u751f\u547d\u533b\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc\u3001\uff12\u6771\u4eac\u6148\u6075\u4f1a\u533b\u79d1\u5927\u5b66\u5c0f\u5150\u79d1\u5b66\u8b1b\u5ea7\uff09
\n\u7b2c1\u8457\u8005\u3068\u7b2c2\u8457\u8005\u306fEqual first author
\n\u7b2c2\u8457\u8005\u3068\u7b2c3\u8457\u8005\u306fCo-corresponding authors<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u533b\u5b66\u5206\u91ce\u306e\u91cd\u8981\u8ab2\u984c\u3067\u3042\u308b\u601d\u6625\u671f\u767a\u6765\u969c\u5bb3\u3092\u5c0e\u304f\u8133\u5185\u6a5f\u69cb\u3092\u89e3\u660e \u30d2\u30c8\u306e\u751f\u6b96\u53ef\u80fd\u3068\u306a\u308b\u91cd\u8981\u306a\u6642\u671f\u3067\u306e\u969c\u5bb3\u306b\u60a9\u3080\u591a\u304f\u306e\u60a3\u8005\u306e\u6cbb\u7642\u6cd5\u958b\u767a\u3078 \u65e9\u7a32\u7530\u5927\u5b66\u6559\u80b2\u30fb\u7dcf\u5408\u79d1\u5b66\u5b66\u8853\u9662\/\u5148\u7aef\u751f\u547d\u533b\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc\uff08TWIns\uff09\u306e\u6e05\u539f\u7f8e\u4f73\uff08\u304d\u3088\u306f\u3089 […]<\/p>\n","protected":false},"author":1,"featured_media":50484,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[357,5],"class_list":["post-50367","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/50367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=50367"}],"version-history":[{"count":1,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/50367\/revisions"}],"predecessor-version":[{"id":50485,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/50367\/revisions\/50485"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/50484"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=50367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=50367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=50367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}