{"id":44517,"date":"2016-09-12T18:00:32","date_gmt":"2016-09-12T09:00:32","guid":{"rendered":"https:\/\/www.waseda.jp\/top\/?p=44517"},"modified":"2016-09-13T16:31:20","modified_gmt":"2016-09-13T07:31:20","slug":"%e8%83%8e%e7%94%9f%e5%8b%95%e7%89%a9%e5%87%ba%e7%8f%be%e3%81%ae%e9%8d%b5-%ef%bc%9a-%e7%b3%96%e3%81%ab%e3%82%88%e3%82%8b%e6%96%b0%e3%81%9f%e3%81%aa%e3%82%a8%e3%83%94%e3%82%b8%e3%82%a7%e3%83%8d%e3%83%86","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/44517","title":{"rendered":"\u80ce\u751f\u52d5\u7269\u51fa\u73fe\u306e\u9375\uff1a\u7cd6\u306b\u3088\u308b\u65b0\u305f\u306a\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u4fee\u98fe\u3092\u767a\u898b \u54fa\u4e73\u985e\u306b\u7279\u6709\u306a\u75c5\u6c17\u306e\u539f\u56e0\u89e3\u660e\u3001\u6cbb\u7642\u958b\u767a\u306b\u6804\u990a\u5b66\u7684\u89b3\u70b9\u304b\u3089\u671f\u5f85"},"content":{"rendered":"<p style=\"text-align: left;\">\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u7dcf\u5408\u7814\u7a76\u6240\u306e<a href=\"https:\/\/researchers.waseda.jp\/profile\/ja.02885abb0ff3e7d65f74241b4b11e2f0.html\" target=\"_blank\">\u5869\u7530\u90a6\u90ce\u4e0a\u7d1a\u7814\u7a76\u54e1\uff08\u7814\u7a76\u9662\u6559\u6388\uff09<\/a>\u3068<a href=\"https:\/\/researchers.waseda.jp\/profile\/ja.751d3a81269f5c132c2928477c1106f0.html\" target=\"_blank\">\u65b0\u4e95\u5927\u7950\u6b21\u5e2d\u7814\u7a76\u54e1\uff08\u7814\u7a76\u9662\u8b1b\u5e2b\uff09<\/a>\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001<a href=\"http:\/\/www.a.u-tokyo.ac.jp\/topics\/2016\/20160912-1.html\" target=\"_blank\">\u6771\u4eac\u5927\u5b66<\/a>\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u3068\u5171\u540c\u3067\u3001\u7cd6(N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3)\u306b\u3088\u308b\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u5316\u5b66\u4fee\u98fe\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u4eca\u56de\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u82f1\u56fdNature Publishing Group\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u79d1\u5b66\u96d1\u8a8c\u300e<a href=\"http:\/\/www.nature.com\/articles\/srep31785\" target=\"_blank\">Scientific Reports<\/a>\u300f\u306b\u3001\u65e5\u672c\u6642\u9593\uff19\u6708\uff11\uff12\u65e5\u5348\u5f8c\uff16\u6642\uff08\u73fe\u5730\u6642\u9593\uff1a\uff19\u6708\uff11\uff12\u65e5\u5348\u524d\uff11\uff10\u6642\uff09\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h3 style=\"text-align: left;\">\u30dd\u30a4\u30f3\u30c8<\/h3>\n<ul>\n<li>\u9032\u5316\u306e\u4e0a\u3067\u80ce\u751f\u52d5\u7269\u51fa\u73fe\u306e\u9375\u3068\u306a\u308b\u65b0\u898f\u306e\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u4fee\u98fe<sup>\uff08\u6ce81\uff09<\/sup>\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<\/li>\n<li>\u767a\u898b\u3057\u305f\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe<sup>\uff08\u6ce82\uff09<\/sup>\u306f\u3001\u80ce\u751f\u52d5\u7269\u306b\u7279\u6709\u3067\u3042\u308b\u3002\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u306e\u6709\u7121\u306b\u3088\u308a\u751f\u3058\u308b\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0<sup>\uff08\u6ce83\uff09<\/sup>\u306e\u591a\u69d8\u6027\u304c\u3001\u907a\u4f1d\u5b50\u5236\u5fa1\u3092\u3055\u3089\u306b\u8907\u96d1\u306b\u3057\u307e\u3059\u3002<\/li>\n<li>\u767a\u898b\u3055\u308c\u305f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u4fee\u98fe\u306f\u3001\u80ce\u751f\u52d5\u7269\u7279\u6709\u306e\u767a\u751f\u6a5f\u69cb\u3042\u308b\u3044\u306f\u75c5\u6c17\u306e\u539f\u56e0\u306e\u89e3\u660e\u306b\u65b0\u305f\u306a\u8996\u70b9\u3092\u63d0\u4f9b\u3067\u304d\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u767a\u8868\u6982\u8981<\/h3>\n<p>\u30b2\u30ce\u30e0DNA\u306f\u30d2\u30b9\u30c8\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5dfb\u304d\u4ed8\u3044\u3066\u3001\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u69cb\u9020\u3092\u3068\u3063\u3066\u3044\u308b\u3002\u3053\u306e\u69cb\u9020\u306f\u3001\u907a\u4f1d\u5b50\u304c\u3044\u304b\u306b\u4f7f\u308f\u308c\u308b\u304b\u306b\u5f71\u97ff\u3059\u308b\u3002\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u8fb2\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u306e\u5ee3\u6fa4\u745e\u5b50\u52a9\u6559\u3001\u65e9\u5ddd\u6643\u53f8\u7279\u4efb\u52a9\u6559\u3001\u7530\u4e2d\u667a\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u65e9\u7a32\u7530\u5927\u5b66\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u3068\u5171\u540c\u3067\u3001\u7cd6(N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3)\u306b\u3088\u308b\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u5316\u5b66\u4fee\u98fe\u3092\u767a\u898b\u3057\u305f\u3002\u3053\u306e\u7cd6\u4fee\u98fe\u306f\u4e00\u822c\u7684\u306b\u6804\u990a\u5fdc\u7b54\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3001\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u69cb\u9020\u306b\u5f37\u304f\u95a2\u4e0e\u3059\u308b\u90e8\u4f4d\u306b\u5b58\u5728\u3057\u3066\u3044\u305f\u3002\u30d2\u30b9\u30c8\u30f3\u306b\u306f\u591a\u304f\u306e\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0<sup>\uff08\u6ce84\uff09<\/sup>\u304c\u5b58\u5728\u3059\u308b\u304c\u3001\u4e92\u3044\u306b\u6975\u3081\u3066\u76f8\u540c\u6027\u304c\u9ad8\u304f\u3001\u6570\u500b\u306e\u30a2\u30df\u30ce\u9178\u306e\u9055\u3044\u304c\u3042\u308b\u306e\u307f\u3067\u3001\u3053\u308c\u307e\u3067\u306f\u540c\u4e00\u8996\u3055\u308c\u3066\u304d\u305f\u3002\u3057\u304b\u3057\u3001\u767a\u898b\u3055\u308c\u305f\u65b0\u305f\u306a\u7cd6\u4fee\u98fe\u306f\u3001\u80ce\u751f\u52d5\u7269\u306b\u7279\u5fb4\u7684\u306a\u30d2\u30b9\u30c8\u30f3\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u306b\u306e\u307f\u4ed8\u52a0\u3067\u304d\u308b\u305f\u3081\u3001\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u306b\u306f\u500b\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u751f\u7269\u9032\u5316\u306e\u904e\u7a0b\u306b\u304a\u3051\u308b\u591a\u69d8\u6027\u306e\u5b9f\u73fe\u306f\u3001\u907a\u4f1d\u5b50\u6570\u306e\u5897\u52a0\u3060\u3051\u3067\u306f\u8aac\u660e\u304c\u96e3\u3057\u3044\u3002\u80ce\u751f\u52d5\u7269\u304c\u51fa\u73fe\u3057\u305f\u6642\u671f\u306b\u3001\u308f\u305a\u304b\u4e00\u3064\u306e\u30a2\u30df\u30ce\u9178\u306e\u5909\u7570\u304c\u304a\u3053\u3063\u3066\u3001\u30d2\u30b9\u30c8\u30f3\u306e\u7cd6\u4fee\u98fe\u304c\u53ef\u80fd\u306b\u306a\u3063\u305f\u3002\u305d\u308c\u306b\u3088\u3063\u3066\u751f\u3058\u305f\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u306e\u591a\u69d8\u6027\u304c\u907a\u4f1d\u5b50\u5229\u7528\u306e\u591a\u69d8\u6027\u306b\u7e4b\u304c\u3063\u305f\u3068\u8003\u3048\u308b\u3068\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u9032\u5316\u304c\u80ce\u751f\u52d5\u7269\u306e\u51fa\u73fe\u306b\u5bc4\u4e0e\u3057\u305f\u3053\u3068\u304c\u60f3\u8d77\u3055\u308c\u308b\uff08\u56f3\uff11\uff09\u3002\u3053\u306e\u7cd6\u4fee\u98fe\u3092\u7279\u7570\u7684\u306b\u8a8d\u8b58\u3059\u308b\u5358\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u306f\u3001\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u89e3\u660e\u3078\u306e\u5f37\u529b\u306a\u30c4\u30fc\u30eb\u3068\u306a\u308a\u3001\u7279\u306b\u3001\u54fa\u4e73\u985e\u306b\u7279\u6709\u306a\u75c5\u6c17\u306e\u539f\u56e0\u89e3\u660e\u3042\u308b\u3044\u306f\u6cbb\u7642\u958b\u767a\u306b\u3001\u6804\u990a\u5b66\u7684\u89b3\u70b9\u304b\u3089\u5a01\u529b\u3092\u767a\u63ee\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/p>\n<div id=\"attachment_44603\" class=\"wp-caption alignnone\"><a href=\"http:\/\/www.waseda.jp\/top\/assets\/uploads\/2016\/09\/20160908_fig1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-44603 size-full\" src=\"http:\/\/www.waseda.jp\/top\/assets\/uploads\/2016\/09\/20160908_fig1.png\" alt=\"20160908_fig1\" width=\"624\" height=\"696\" srcset=\"https:\/\/www.waseda.jp\/top\/assets\/uploads\/2016\/09\/20160908_fig1.png 624w, https:\/\/www.waseda.jp\/top\/assets\/uploads\/2016\/09\/20160908_fig1-610x680.png 610w\" sizes=\"auto, (max-width: 624px) 100vw, 624px\" \/><\/a><p class=\"wp-caption-text\">\uff08\u56f31\uff09\u9032\u5316\u904e\u7a0b\u306b\u304a\u3051\u308bH2AS40\u7cd6\u4fee\u98fe\u306e\u7372\u5f97\uff1a\u9032\u5316\u4e0a\u3001\u4e00\u3064\u306e\u30a2\u30df\u30ce\u9178\u306e\u7f6e\u63db\u306b\u3088\u3063\u3066\u65b0\u898f\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u304c\u7372\u5f97\u3055\u308c\u305f\u3002\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u306b\u3088\u308b\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u69cb\u9020\u306e\u591a\u69d8\u6027\u304c\u907a\u4f1d\u5b50\u5229\u7528\u306e\u591a\u69d8\u6027\u306b\u7e4b\u304c\u308a\u3001\u80ce\u751f\u52d5\u7269\u306e\u51fa\u73fe\u306b\u5bc4\u4e0e\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p><\/div>\n<h3>\u7528\u8a9e\u89e3\u8aac<\/h3>\n<ul>\n<li><strong>\uff08\u6ce81\uff09\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\uff1a<\/strong>DNA\u306e\u5869\u57fa\u914d\u5217\u306e\u5909\u5316\u3092\u4f34\u308f\u305a\u306b\u7d30\u80de\u5206\u88c2\u5f8c\u3082\u4f1d\u9054\u3055\u308c\u308b\u907a\u4f1d\u5b50\u6a5f\u80fd\u306e\u5909\u5316\u306b\u3064\u3044\u3066\u63a2\u6c42\u3059\u308b\u5b66\u554f\u9818\u57df\u3092\u610f\u5473\u3059\u308b\u3002DNA\u30e1\u30c1\u30eb\u5316\u3068\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u3063\u3066\u3001\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u69cb\u9020\u304c\u5909\u5316\u3057\u3001\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u72b6\u614b\u3084\u30b2\u30ce\u30e0\u306e\u5b89\u5b9a\u5316\u3001\u304a\u3088\u3073DNA\u8907\u88fd\u306a\u3069\u306e\u8abf\u7bc0\u3092\u884c\u3046\u3002<\/li>\n<li><strong>\uff08\u6ce82\uff09\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\uff1a<\/strong>\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u306f\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u4fee\u98fe\u306e\u4e00\u3064\u3067\u3042\u308b\u3002\u30d2\u30b9\u30c8\u30f3\u5206\u5b50\u306f\u69d8\u3005\u306a\u5316\u5b66\u4fee\u98fe\u3092\u53d7\u3051\u3066\u3044\u308b\u3002\u4e2d\u3067\u3082\u7cd6\u306b\u3088\u308b\u30d2\u30b9\u30c8\u30f3\u306e\u4fee\u98fe\u306b\u8fd1\u5e74\u95a2\u5fc3\u304c\u6301\u305f\u308c\u3066\u3044\u308b\u3002\u30d2\u30b9\u30c8\u30f3\u304c\u3069\u306e\u5206\u5b50\u3067\u4fee\u98fe\u3055\u308c\u308b\u304b\u3001\u307e\u305f\u3001\u30d2\u30b9\u30c8\u30f3\u306e\u30a2\u30df\u30ce\u9178\u914d\u5217\u4e2d\u306e\u3069\u306e\u30a2\u30df\u30ce\u9178\u304c\u4fee\u98fe\u3055\u308c\u308b\u304b\u306b\u3088\u3063\u3066\u3001\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u3042\u308b\u3044\u306f\u4f11\u7720\u306e\u72b6\u614b\u3092\u4f5c\u308a\u3060\u3059\u3002<\/li>\n<li><strong>\uff08\u6ce83\uff09\u30cc\u30af\u30ec\u30bd\u30fc\u30e0\uff1a<\/strong>\u67d3\u8272\u4f53\u306e\u57fa\u672c\u69cb\u6210\u5358\u4f4d\u3067\u30018\u500b\u306e\u30d2\u30b9\u30c8\u30f3\u5206\u5b50\u3092\u82af\u3068\u3057\u3066\u3001DNA\u304c2\u56de\u5dfb\u304d\u4ed8\u3044\u305f\u69cb\u9020\u3067\u3042\u308b\u3002\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u304c\u96c6\u307e\u3063\u3066\u3001\u6298\u308a\u305f\u305f\u307e\u308c\u51dd\u7e2e\u3057\u30af\u30ed\u30de\u30c1\u30f3\u3068\u306a\u308b\u3002\u30af\u30ed\u30de\u30c1\u30f3\u304c\u3055\u3089\u306b\u6298\u308a\u305f\u305f\u307e\u308c\u305f\u3082\u306e\u304c\u67d3\u8272\u4f53\u3067\u3042\u308b\u3002<\/li>\n<li><strong>\uff08\u6ce84\uff09\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0<\/strong><br \/>\n\u57fa\u672c\u7684\u6a5f\u80fd\u306b\u304b\u304b\u308f\u308b\u30a2\u30df\u30ce\u9178\u914d\u5217\u306f\u5171\u901a\u3057\u3066\u3044\u308b\u304c\u3001\u4e00\u90e8\u306e\u914d\u5217\u304c\u7570\u306a\u3063\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u3068\u3044\u3046\u3002<\/li>\n<\/ul>\n<h3>\u767a\u8868\u8005<\/h3>\n<ul>\n<li>\u5ee3\u6fa4\u745e\u5b50 \uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u8fb2\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u3000\u5fdc\u7528\u52d5\u7269\u79d1\u5b66\u5c02\u653b\u3000\u52a9\u6559\uff09<\/li>\n<li>\u65e9\u5ddd\u6643\u53f8 \uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u8fb2\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u3000\u5fdc\u7528\u52d5\u7269\u79d1\u5b66\u5c02\u653b\u3000\u7279\u4efb\u52a9\u6559\uff09<\/li>\n<li>\u7530\u4e2d\u3000\u667a \uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u8fb2\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u3000\u5fdc\u7528\u52d5\u7269\u79d1\u5b66\u5c02\u653b\u3000\u51c6\u6559\u6388\uff09<\/li>\n<li>\u5802\u524d\u3000\u76f4 \uff08\u7406\u5316\u5b66\u7814\u7a76\u6240 \u74b0\u5883\u8cc7\u6e90\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc \u751f\u547d\u5206\u5b50\u89e3\u6790\u30e6\u30cb\u30c3\u30c8 \u30e6\u30cb\u30c3\u30c8\u30ea\u30fc\u30c0\u30fc\uff09<\/li>\n<li>\u65b0\u4e95\u5927\u7950 \uff08\u65e9\u7a32\u7530\u5927\u5b66\u3000\u7406\u5de5\u5b66\u8853\u9662\u7dcf\u5408\u7814\u7a76\u6240\u3000\u6b21\u5e2d\u7814\u7a76\u54e1\u30fb\u7814\u7a76\u9662\u8b1b\u5e2b\uff09<\/li>\n<li>\u5869\u7530\u90a6\u90ce \uff08\u65e9\u7a32\u7530\u5927\u5b66\u3000\u7406\u5de5\u5b66\u8853\u9662\u7dcf\u5408\u7814\u7a76\u6240\u3000\u4e0a\u7d1a\u7814\u7a76\u54e1\u30fb\u7814\u7a76\u9662\u6559\u6388\uff0f\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u8fb2\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u3000\u540d\u8a89\u6559\u6388\uff09<\/li>\n<\/ul>\n<h3>\u767a\u8868\u5185\u5bb9<\/h3>\n<h4>\u2460 \u7814\u7a76\u306e\u80cc\u666f<\/h4>\n<p>\u30d2\u30b9\u30c8\u30f3\u306f\u3001\u9577\u3044\u30b2\u30ce\u30e0DNA\u5206\u5b50\u3092\u6298\u308a\u305f\u305f\u3093\u3067\u6838\u5185\u306b\u53ce\u7d0d\u3059\u308b\u3068\u3044\u3046\u3001\u751f\u547d\u73fe\u8c61\u306e\u6839\u6e90\u306b\u6df1\u304f\u304b\u304b\u308f\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u591a\u304f\u306e\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3002\u30d2\u30b9\u30c8\u30f3\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u7fa4\u306f\u76f8\u540c\u6027\u304c\u6975\u3081\u3066\u9ad8\u304f\u3001\u6570\u500b\u306e\u30a2\u30df\u30ce\u9178\u3057\u304b\u9055\u308f\u306a\u3044\u305f\u3081\u3001\u3053\u308c\u307e\u3067\u3001\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u9593\u3067\u306e\u6a5f\u80fd\u5dee\u306f\u8b70\u8ad6\u3055\u308c\u305a\u306b\u304d\u305f\u3002\u30d2\u30b9\u30c8\u30f3\u304c\u3055\u307e\u3056\u307e\u306a\u5316\u5b66\u4fee\u98fe\u3092\u53d7\u3051\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u5236\u5fa1\u306e\u4e2d\u5fc3\u3068\u3057\u3066\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5236\u5fa1\u306b\u95a2\u4e0e\u3059\u308b\u3002\u4f53\u3092\u69cb\u6210\u3059\u308b\u3059\u3079\u3066\u306e\u7d30\u80de\u3067\u540c\u3058\u30b2\u30ce\u30e0DNA\u3092\u6301\u3063\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u7d30\u80de\u56fa\u6709\u306e\u907a\u4f1d\u5b50\u306e\u5229\u7528\u304c\u3067\u304d\u308b\u306e\u306f\u3001\u30d2\u30b9\u30c8\u30f3\u5316\u5b66\u4fee\u98fe\u3092\u57fa\u76e4\u3068\u3059\u308b\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u306e\u591a\u69d8\u6027\u306b\u3088\u308b\u3068\u3053\u308d\u304c\u5927\u304d\u3044\u3002<\/p>\n<p>\u5358\u7cd6\u3067\u3042\u308bN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u304c\u30bb\u30ea\u30f3\uff08Ser\uff09\u3042\u308b\u3044\u306f\u30b9\u30ec\u30aa\u30cb\u30f3\uff08Thr\uff09\u6b8b\u57fa\u306b\u4ed8\u52a0\u3059\u308b\u7ffb\u8a33\u5f8c\u306e\u7cd6\u4fee\u98fe\u3082\u3001\u30e1\u30c1\u30eb\u5316\u3084\u30a2\u30bb\u30c1\u30eb\u5316\u3068\u4e26\u3093\u3067\u3001\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u5316\u5b66\u4fee\u98fe\u3068\u3057\u3066\u63d0\u5531\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u306e\u7cd6\u4fee\u98fe\u81ea\u4f53\u3001\u4e00\u822c\u7684\u306b\u6804\u990a\u5fdc\u7b54\u6027\u3092\u6709\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u65b0\u305f\u306a\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u30d1\u30e9\u30e1\u30fc\u30bf\u30fc\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u3001\u4fee\u98fe\u306e\u5b89\u5b9a\u6027\u3084\u5fae\u91cf\u306a\u4fee\u98fe\u91cf\u304c\u554f\u984c\u3068\u306a\u308b\u306e\u304b\u3001\u7cd6\u4fee\u98fe\u540c\u5b9a\u306e\u518d\u73fe\u304c\u56f0\u96e3\u3067\u3001\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u306e\u7814\u7a76\u306f\u3053\u308c\u307e\u3067\u9650\u3089\u308c\u3066\u3044\u305f\u3002<\/p>\n<p>\u30b2\u30ce\u30e0DNA\u5168\u4f53\u306e\u5897\u5e45\u306f\u9032\u5316\u4e0a\u3001\u91cd\u8981\u306a\u4f4d\u7f6e\u3092\u5360\u3081\u3066\u3044\u308b\u3002\u771f\u6838\u751f\u7269\u304c\u8a95\u751f\u3057\u810a\u690e\u52d5\u7269\u306b\u81f3\u308b\u307e\u3067\u306b\uff12\u56de\u306e\u30b2\u30ce\u30e0\u5168\u4f53\u306e\u5897\u5e45\u304c\u8d77\u3053\u308a\u3001\u9b5a\u985e\u3078\u306e\u9032\u5316\u306e\u904e\u7a0b\u3067\u3001\uff13\u56de\u76ee\u306e\u5897\u5e45\u304c\u3042\u3063\u305f\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u308b\u3002\u3053\u306e\u3088\u3046\u306b\uff13\u56de\u76ee\u306e\u5897\u5e45\u306f\u54fa\u4e73\u985e\u306e\u9032\u5316\u3078\u306f\u3064\u306a\u304c\u3063\u3066\u3044\u306a\u3044\u3002\u3069\u306e\u3088\u3046\u306a\u30b2\u30ce\u30e0\u5909\u5316\u304c\u54fa\u4e73\u985e\u3078\u306e\u9032\u5316\u3092\u53ef\u80fd\u306b\u3057\u305f\u306e\u3060\u308d\u3046\u304b\uff1f\u80ce\u76e4\u7372\u5f97\u3068\u3044\u3046\u9032\u5316\u4e0a\u306e\u4e00\u5927\u30a4\u30d9\u30f3\u30c8\u306f\u3001\u5fc5\u8981\u306a\u907a\u4f1d\u5b50\u304c\u65b0\u898f\u306b\u8a95\u751f\u3057\u305f\u3068\u3044\u3046\u3088\u308a\u3001\u3059\u3067\u306b\u5b58\u5728\u3059\u308b\u907a\u4f1d\u5b50\u3092\u3044\u304b\u306b\u4f7f\u3046\u304b\u306b\u9375\u304c\u3042\u3063\u305f\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n<h4>\u2461 \u7814\u7a76\u5185\u5bb9<strong><br \/>\n<\/strong><\/h4>\n<p>\u672c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30de\u30a6\u30b9\u80da\u6027\u5e79\u7d30\u80de\u304b\u3089\u7cbe\u88fd\u3057\u305f\u30b3\u30a2\u30d2\u30b9\u30c8\u30f3\u306e\u8cea\u91cf\u5206\u6790\u306b\u3088\u308a\u3001\u7cd6\u4fee\u98fe\u90e8\u4f4d\u306e\u5019\u88dc\u7fa4\u3092\u540c\u5b9a\u3057\u3001\u7cd6\u30da\u30d7\u30c1\u30c9\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u3092\u4f5c\u88fd\u3057\u305f\u3002\u305d\u308c\u3092\u6297\u539f\u3068\u3057\u3066\u5f97\u3089\u308c\u305f\u5358\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f5320B2\u306f\u3001HPLC\u306b\u3088\u308b\u30d2\u30b9\u30c8\u30f3\u5206\u753b\u304a\u3088\u3073\u7d44\u63db\u3048\u5909\u7570\u4f53\u5229\u7528\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u3001H2A\u306eL1\u9818\u57df\u306b\u3042\u305f\u308b40\u756a\u76ee\u306e\u30bb\u30ea\u30f3\u306b\u4ed8\u52a0\u3059\u308b\u7cd6\u4fee\u98fe\u3092\u8a8d\u8b58\u3059\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u3001\u6700\u7d42\u7684\u306b\u305d\u306e\u5b58\u5728\u304c\u8cea\u91cf\u5206\u6790\u306b\u3088\u308a\u78ba\u8a8d\u3055\u308c\u305f\u3002\u7cd6\u4fee\u98fe\u7279\u7570\u7684\u306a\u5358\u30af\u30ed\u30fc\u30f3\u6297\u4f53\u304c\u5f97\u3089\u308c\u305f\u3053\u3068\u306b\u3088\u308a\u3001\u305d\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u306e\u89e3\u660e\u304c\u98db\u8e8d\u7684\u306b\u9032\u3080\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/p>\n<p>\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u30b2\u30ce\u30e0\u60c5\u5831\u3092\u89e3\u6790\u3059\u308b\u3068\u3001\u9175\u6bcd\u304b\u3089\u5358\u5b54\u985e\u306b\u81f3\u308b\u307e\u3067\u306f\u3001H2A\u306e40\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u304c\u30a2\u30e9\u30cb\u30f3\u3067\u3042\u308b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\uff08H2AA<sup>40<\/sup>\uff09\u306e\u307f\u3057\u304b\u5b58\u5728\u3057\u306a\u3044\u3002\u4f8b\u3048\u3070\u3001\u30bc\u30d6\u30e9\u30d5\u30a3\u30c3\u30b7\u30e5\u3001\u30ab\u30a8\u30eb\u3067\u3001\uff12\uff19\u500b\u3001\u30ab\u30e2\u30ce\u30cf\u30b7\u3067\u3082\uff12\uff14\u500b\u304b\u3089\u306a\u308b\u30d2\u30b9\u30c8\u30f3\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u7fa4\u306e\u3059\u3079\u3066\u304c\u3001\u7cd6\u4fee\u98fe\u304c\u3064\u3051\u306a\u3044H2AA<sup>40<\/sup>\u30bf\u30a4\u30d7\u306e\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u3067\u3042\u308b\u3002\u4e00\u65b9\u3001\u80ce\u751f\u52d5\u7269\u4ee5\u964d\u306b\u306a\u3063\u3066\u3001\uff14\uff10\u756a\u76ee\u306e\u30a2\u30df\u30ce\u9178\u304c\u30a2\u30e9\u30cb\u30f3\u3067\u306f\u306a\u304f\u3001\u7cd6\u4fee\u98fe\u304c\u4ed8\u52a0\u3067\u304d\u308b\u30bb\u30ea\u30f3\u3067\u3042\u308b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\uff08H2AS<sup>40<\/sup>\uff09\u304c\u51fa\u73fe\u3057\u3066\u304d\u305f\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u80ce\u751f\u52d5\u7269\u306e\u30ef\u30e9\u30d3\u30fc\u306f\u3001\uff15\u500b\u304b\u3089\u306a\u308b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u7fa4\u4e2d\uff13\u500b\u3001\u30de\u30a6\u30b9\u3067\u306f\uff11\uff18\u500b\u4e2d\uff11\uff13\u500b\u3001\u305d\u3057\u3066\u30d2\u30c8\u3067\u306f\u3001\uff11\uff17\u500b\u4e2d\uff14\u500b\u304c\u7cd6\u4fee\u98fe\u578b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u3067\u3042\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u65b0\u898f\u306e\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u306f\u3001\u80ce\u751f\u52d5\u7269\u306b\u306e\u307f\u5b58\u5728\u3059\u308b\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u7279\u7570\u7684\u306a\u4fee\u98fe\u3067\u3042\u308b\u3068\u3044\u3046\u7279\u5fb4\u3092\u3082\u3061\u3001\u30d2\u30b9\u30c8\u30f3\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u9593\u306e\u308f\u305a\u304b\u306a\u5dee\u7570\u3082\u7121\u8996\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002<\/p>\n<p>\u9032\u5316\u4e0a\u3001\u4fdd\u5b58\u6027\u304c\u6975\u3081\u3066\u9ad8\u3044\u30d2\u30b9\u30c8\u30f3\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u9593\u3067\u751f\u307e\u308c\u305f\u308f\u305a\u304b\u4e00\u3064\u306e\u30a2\u30df\u30ce\u9178\u306e\u7f6e\u63db\u304c\u3001\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u306e\u7372\u5f97\u3092\u3072\u304d\u304a\u3053\u3057\u305f\u3002L1\u9818\u57df\u306f\u3001\u30d2\u30b9\u30c8\u30f38\u91cf\u4f53\u306b\u542b\u307e\u308c\u308bH2A\u5206\u5b50\u540c\u58eb\u304c\u4f1a\u5408\u3059\u308b\u9818\u57df\u3067\u3001\u305d\u3053\u3067\u306e\u7cd6\u4fee\u98fe\u306e\u6709\u7121\u306f\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u69cb\u9020\u306b\u5927\u304d\u306a\u5909\u5316\u3092\u3082\u305f\u3089\u3059\u3068\u8003\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u65b0\u3057\u3044\u7cd6\u4fee\u98fe\u306e\u7372\u5f97\u306b\u3088\u3063\u3066\u751f\u3058\u305f\u30cc\u30af\u30ec\u30aa\u30bd\u30fc\u30e0\u306e\u591a\u69d8\u6027\u304c\u3001\u907a\u4f1d\u5b50\u5229\u7528\u306e\u591a\u69d8\u6027\u3092\u751f\u307f\u3001\u80ce\u751f\u52d5\u7269\u306e\u51fa\u73fe\u306b\u7e4b\u304c\u3063\u305f\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n<h4>\u2462 \u793e\u4f1a\u7684\u610f\u7fa9<\/h4>\n<p>\u80ce\u751f\u52d5\u7269\u7279\u7570\u7684\u306a\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u306e\u767a\u898b\u306f\u6975\u3081\u3066\u65b0\u898f\u6027\u306b\u5bcc\u3093\u3067\u3044\u308b\u3002\u3053\u306e\u7cd6\u4fee\u98fe\u306f\u30b0\u30eb\u30b3\u30fc\u30b9\u4ee3\u8b1d\u3068\u5bc6\u63a5\u306a\u95a2\u4fc2\u306b\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3001\u80ce\u751f\u306b\u3088\u308b\u767a\u751f\u6a5f\u69cb\u306e\u89e3\u660e\u306b\u52a0\u3048\u3001\u54fa\u4e73\u985e\u7279\u6709\u306e\u4ee3\u8b1d\u95a2\u9023\u75be\u60a3\u306e\u6cbb\u7642\u306b\u5bfe\u3057\u3066\u3001\u6804\u990a\u3068\u3044\u3046\u8996\u70b9\u304b\u3089\u3001\u65b0\u898f\u30d2\u30b9\u30c8\u30f3\u7cd6\u4fee\u98fe\u3092\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u3068\u3057\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u3068\u306a\u308b\u3002<\/p>\n<h3><strong>\u767a\u8868\u96d1\u8a8c<\/strong><\/h3>\n<p>\u96d1\u8a8c\u540d\uff1a\u300cScientific Reports\u300d<\/p>\n<p>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb\uff1aNovel <em>O<\/em>-GlcNAcylation on Ser<sup>40 <\/sup>of canonical H2A isoforms specific to viviparity<strong>.<br \/>\n<\/strong><\/p>\n<p>\u8457\u8005\uff1a Mitsuko Hirosawa*, Koji Hayakawa*, Chikako Yoneda, Daisuke Arai, Hitoshi Shiota, Takehiro Suzuki, Satoshi Tanaka, Naoshi Dohmae and Kunio Shiota*<\/p>\n<p>\u8ad6\u6587URL\uff1a<a href=\"http:\/\/www.nature.com\/articles\/srep31785\" target=\"_blank\">http:\/\/www.nature.com\/articles\/srep31785<\/a><\/p>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\u7dcf\u5408\u7814\u7a76\u6240\u306e\u5869\u7530\u90a6\u90ce\u4e0a\u7d1a\u7814\u7a76\u54e1\uff08\u7814\u7a76\u9662\u6559\u6388\uff09\u3068\u65b0\u4e95\u5927\u7950\u6b21\u5e2d\u7814\u7a76\u54e1\uff08\u7814\u7a76\u9662\u8b1b\u5e2b\uff09\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6771\u4eac\u5927\u5b66\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u3068\u5171\u540c\u3067\u3001\u7cd6(N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3)\u306b\u3088\u308b\u65b0\u305f\u306a\u30d2\u30b9\u30c8\u30f3\u5316\u5b66\u4fee\u98fe\u3092\u767a\u898b\u3057\u307e\u3057 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":44518,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[5],"class_list":["post-44517","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/44517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=44517"}],"version-history":[{"count":1,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/44517\/revisions"}],"predecessor-version":[{"id":44602,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/44517\/revisions\/44602"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/44518"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=44517"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=44517"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=44517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}