{"id":16967,"date":"2014-11-21T15:08:56","date_gmt":"2014-11-21T06:08:56","guid":{"rendered":"http:\/\/www.waseda.jp\/top\/?p=16967"},"modified":"2014-11-21T15:49:38","modified_gmt":"2014-11-21T06:49:38","slug":"%e8%84%b3%e7%a5%9e%e7%b5%8c%e3%82%b7%e3%83%8a%e3%83%97%e3%82%b9%e3%81%ae%e3%82%b9%e3%83%91%e3%82%a4%e3%83%b3%e5%af%86%e5%ba%a6%e3%82%92%e5%88%b6%e5%be%a1%e3%81%99%e3%82%8b%e4%bb%95%e7%b5%84%e3%81%bf","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/top\/news\/16967","title":{"rendered":"\u8133\u795e\u7d4c\u30b7\u30ca\u30d7\u30b9\u306e\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u3092\u5236\u5fa1\u3059\u308b\u4ed5\u7d44\u307f\u306e\u4e00\u7aef\u3092\u89e3\u660e\u3000\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u306e\u75c5\u614b\u89e3\u660e\u306b\u671f\u5f85"},"content":{"rendered":"

\u7406\u5de5\u5b66\u8853\u9662\u30fb\u5927\u5cf6\u767b\u5fd7\u7537\u6559\u6388\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u8133\u5185\u3067\u795e\u7d4c\u7d30\u80de\u304c\u60c5\u5831\u4f1d\u9054\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u30b7\u30ca\u30d7\u30b9\uff08\u795e\u7d4c\u7d30\u80de\u540c\u58eb\u306e\u3064\u306a\u304e\u76ee\uff09\u3068\u3001\u305d\u306e\u4e00\u90e8\u3067\u3042\u308a\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3092\u53d7\u3051\u53d6\u308b\u5f79\u5272\u3092\u62c5\u3046\u30b9\u30d1\u30a4\u30f3\uff08\u795e\u7d4c\u7d30\u80de\u306e\u6a39\u72b6\u7a81\u8d77\u306b\u3042\u308b\u3068\u3052\u72b6\u306e\u69cb\u9020\u7269\uff09\u306e\u4ed5\u7d44\u307f\u306b\u304a\u3044\u3066\u3001\u30b9\u30d1\u30a4\u30f3\u5f62\u6210\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308b\u30b5\u30a4\u30af\u30ea\u30f3\u4f9d\u5b58\u6027\u30ad\u30ca\u30fc\u30bc\uff15\uff08\u4ee5\u4e0b\u3001Cdk5\uff09\u306b\u6ce8\u76ee\u3057\u3001Cdk5\u304c\u30b9\u30d1\u30a4\u30f3\u306e\u5f62\u6210\u30fb\u7dad\u6301\u306b\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\uff08\u203b\u2460\uff09\u3068\u3001Cdk5\u306e\u6a5f\u80fd\u4f4e\u4e0b\u304c\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u52b9\u7387\u306e\u4f4e\u4e0b\u3068\u8a18\u61b6\u30fb\u5b66\u7fd2\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u62db\u304f\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\uff08\u203b\u2461\uff09\u3002\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u795e\u7d4c\u75be\u60a3\u3067\u306f\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u6b63\u5e38\u306a\u9ad8\u6b21\u8133\u6a5f\u80fd\u306b\u3068\u3063\u3066\u306f\u30b9\u30d1\u30a4\u30f3\u304c\u9069\u5207\u306b\u5f62\u6210\u3055\u308c\u3001\u4e00\u5b9a\u306e\u5bc6\u5ea6\u3067\u7dad\u6301\u3055\u308c\u308b\u3053\u3068\u304c\u91cd\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u795e\u7d4c\u30b7\u30ca\u30d7\u30b9\u306e\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u3092\u5236\u5fa1\u3059\u308b\u4ed5\u7d44\u307f\u306e\u4e00\u7aef\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3053\u3068\u3067\u3001\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u306e\u75c5\u614b\u306e\u89e3\u660e\u304c\u9032\u5c55\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u203b\u2460\u3000\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u82f1\u56fd\u5c02\u9580\u8a8c\uff08Cerebral Cortex\u8a8c\uff09\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\u306b11\u670817\u65e5\u3001\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002
\nCyclin-Dependent Kinase 5 Regulates Dendritic Spine Formation and Maintenance of Cortical Neuron in the Mouse Brain<\/a><\/p>\n

\u203b\u2461\u3000\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u8133\u79d1\u5b66\u7dcf\u5408\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u884c\u52d5\u907a\u4f1d\u5b66\u6280\u8853\u958b\u767a\u30c1\u30fc\u30e0\uff08\u7cf8\u539f\u91cd\u7f8e\u30b7\u30cb\u30a2\u30c1\u30fc\u30e0\u30ea\u30fc\u30c0\u30fc\uff09\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308b\u3082\u306e\u3067\u3001\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u96d1\u8a8cMolecular Brain\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u7248\u306b11\u670818\u65e5\u3001\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002
\nCdk5\/p35 functions as a crucial regulator of spatial learning and memory<\/a><\/p>\n

(1) \u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/h4>\n

\u6211\u3005\u306e\u8133\u3067\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u795e\u7d4c\u7d30\u80de\u304c\u60c5\u5831\u3092\u4f1d\u9054\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u9ad8\u6b21\u306a\u6a5f\u80fd\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3002\u305d\u306e\u60c5\u5831\u306e\u3084\u308a\u3068\u308a\u306b\u5fc5\u8981\u306a\u306e\u304c\u30b7\u30ca\u30d7\u30b9\u3068\u547c\u3070\u308c\u308b\u69cb\u9020\uff0a\uff11\u3067\u3001\u53d7\u3051\u624b\u5074\u306f\u30b9\u30d1\u30a4\u30f3\u3068\u3044\u3046\u7279\u6b8a\u306a\u69cb\u9020\uff0a\uff12\u3092\u4f5c\u3063\u3066\u3001\u4f1d\u9054\u3092\u52b9\u7387\u5316\u3057\u3066\u3044\u308b\u3002\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u304c\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u795e\u7d4c\u75be\u60a3\u3067\u8a8d\u3081\u3089\u308c\u308b\u306a\u3069\u3001\u6b63\u5e38\u306a\u9ad8\u6b21\u8133\u6a5f\u80fd\u306b\u3068\u3063\u3066\u30b9\u30d1\u30a4\u30f3\u304c\u9069\u5207\u306b\u5f62\u6210\u3055\u308c\u3001\u4e00\u5b9a\u306e\u5bc6\u5ea6\u3067\u7dad\u6301\u3055\u308c\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3042\u308b\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u5236\u5fa1\u306e\u4ed5\u7d44\u307f\u306e\u5168\u5bb9\u306f\u307e\u3060\u5206\u304b\u3063\u3066\u3044\u306a\u3044\u3002\u57f9\u990a\u795e\u7d4c\u7d30\u80de\u3092\u7528\u3044\u305f\u5b9f\u9a13\u306a\u3069\u304b\u3089\u3001\u30b5\u30a4\u30af\u30ea\u30f3\u4f9d\u5b58\u6027\u30ad\u30ca\u30fc\u30bc\uff15\uff08Cdk5\uff09\u306e\u95a2\u4e0e\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u305f\u304c\u3001\u3053\u308c\u307e\u3067\u751f\u4f53\u8133\u3067\u306e\u30b9\u30d1\u30a4\u30f3\u5f62\u6210\u3084\u7dad\u6301\u3068Cdk5\u306e\u95a2\u4fc2\u306f\u8abf\u3079\u3089\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3002<\/p>\n

(2) \u4eca\u56de\u306e\u7814\u7a76\u3067\u65b0\u305f\u306b\u5b9f\u73fe\u3057\u3088\u3046\u3068\u3057\u305f\u3053\u3068\u3001\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3053\u3068<\/h4>\n

Cdk5\u304c\u30b9\u30d1\u30a4\u30f3\u306e\u5f62\u6210\u30fb\u7dad\u6301\u306b\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u3068\u3001Cdk5\u306e\u6a5f\u80fd\u4f4e\u4e0b\u304c\u3001\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u52b9\u7387\u306e\u4f4e\u4e0b\u3068\u8a18\u61b6\u30fb\u5b66\u7fd2\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u62db\u304f\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3002\u3053\u306e\u3053\u3068\u306b\u3088\u308a\u3001\u795e\u7d4c\u30b7\u30ca\u30d7\u30b9\u306e\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u3092\u5236\u5fa1\u3059\u308b\u4ed5\u7d44\u307f\u306e\u4e00\u7aef\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3002<\/p>\n

(3) \u305d\u306e\u305f\u3081\u306b\u65b0\u3057\u304f\u958b\u767a\u3057\u305f\u624b\u6cd5<\/h4>\n

\u4eca\u56de\u7528\u3044\u305f\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30ca\u30eb\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u306e\u624b\u6cd5\u306f\u3001\u907a\u4f1d\u5b50\u306e\u6b20\u640d\u3092\u7279\u5b9a\u306e\u6642\u671f\u3001\u7279\u5b9a\u306e\u7d30\u80de\u30fb\u7d44\u7e54\u3067\u306e\u307f\u5f15\u304d\u8d77\u3053\u3059\u6280\u8853\u3067\u3042\u308b\u3002\u4eca\u56de\u6b20\u640d\u3055\u305b\u305f\u907a\u4f1d\u5b50\u306f\u3001\u80ce\u751f\u671f\u304b\u3089\u6b20\u640d\u3055\u305b\u308b\u3068\u30de\u30a6\u30b9\u306e\u65e9\u671f\u81f4\u6b7b\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u8133\u306e\u767a\u751f\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u8133\u304c\u6b63\u5e38\u306b\u51fa\u6765\u3066\u304b\u3089\u907a\u4f1d\u5b50\u6b20\u640d\u3092\u8d77\u3053\u3059\u3053\u3068\u306b\u3088\u308a\u3001\u3088\u308a\u7279\u7570\u7684\u306a\u6a5f\u80fd\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u3063\u3066\u3044\u308b\u3002<\/p>\n

(4) \u4eca\u56de\u306e\u7814\u7a76\u3067\u5f97\u3089\u308c\u305f\u7d50\u679c\u53ca\u3073\u77e5\u898b<\/h4>\n

\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30ca\u30eb\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u3068\u3044\u3046\u907a\u4f1d\u5b50\u6539\u5909\u6280\u8853\u3092\u7528\u3044\u3066\u3001\u30b9\u30d1\u30a4\u30f3\u304c\u5f62\u6210\u3055\u308c\u308b\u6642\u671f\u3088\u308a\u524d\u306b\u907a\u4f1d\u5b50\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u3068\u3001\u4e00\u65e6\u51fa\u6765\u3066\u304b\u3089\u907a\u4f1d\u5b50\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u3067\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u3092\u6bd4\u8f03\u3057\u305f\u3002Cdk5\u306fp35\u307e\u305f\u306fp39\u3068\u7d50\u5408\u3057\u3066\u6d3b\u6027\u5316\u3055\u308c\u308b\u304c\u3001\u3053\u306ep35\u3068p39\u306e\u4e21\u65b9\u306e\u907a\u4f1d\u5b50\u3092\u6b20\u640d\u3055\u305b\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u8a18\u61b6\u30fb\u5b66\u7fd2\u306b\u95a2\u9023\u3059\u308b\u300c\u6d77\u99ac\u300d*3\u3068\u300c\u5927\u8133\u76ae\u8cea\u300d\u306e\u795e\u7d4c\u7d30\u80de\u306b\u304a\u3044\u3066\u3001\u30b9\u30d1\u30a4\u30f3\u5f62\u6210\u524d\u3068\u5f62\u6210\u5f8c\u3067\u907a\u4f1d\u5b50\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u3068\u3082\u306b\u3001\u30b7\u30ca\u30d7\u30b9\u5bc6\u5ea6\u306f\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u305f\uff08\u56f3\uff11)\u3002\u3053\u306e\u3053\u3068\u306fCdk5\u304c\u30b7\u30ca\u30d7\u30b9\u306e\u5f62\u6210\u3068\u7dad\u6301\u306b\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u6d77\u99acCA1\u306e\u795e\u7d4c\u7d30\u80de\u3067\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8p35\u306e\u307f\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u306b\u6bd4\u3079\u3001\u3055\u3089\u306bp39\u907a\u4f1d\u5b50\u3082\u6b20\u640d\u3055\u305b\u3066Cdk5\u6d3b\u6027\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3001\u30b9\u30d1\u30a4\u30f3\u306e\u5bc6\u5ea6\u304c\u66f4\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u305f\uff08\u56f3\uff12\uff09\u3002<\/p>\n

\u307e\u305f\u3001Cdk5\u306e\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8p35\u3092\u6210\u4f53\u8133\u3067\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u306b\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u306b\u52a0\u3048\u3001\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u52b9\u7387\u306e\u4f4e\u4e0b\uff08\u56f3\uff13\uff09\u3068\u30e2\u30ea\u30b9\u6c34\u8ff7\u8def\u8a66\u9a13*4\u3067\u7a7a\u9593\u8a18\u61b6\u306e\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u308b\uff08\u56f3\uff14\uff09\u3053\u3068\u3092\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u8133\u79d1\u5b66\u7dcf\u5408\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u7cf8\u539f\u7814\u7a76\u5ba4\uff08\u7cf8\u539f\u91cd\u7f8e\u30b7\u30cb\u30a2\u30c1\u30fc\u30e0\u30ea\u30fc\u30c0\u30fc\uff09\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u3057\u305f\u3002<\/p>\n

(5) \u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c\u3084\u793e\u4f1a\u7684\u5f71\u97ff<\/h4>\n

\u3053\u308c\u3089\u306e\u7814\u7a76\u6210\u679c\u304b\u3089\u3001Cdk5\u304c\u30b9\u30d1\u30a4\u30f3\u306e\u5f62\u6210\u30fb\u7dad\u6301\u3092\u901a\u3058\u3066\u8133\u306e\u9ad8\u6b21\u6a5f\u80fd\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u6301\u3064\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u304c\u3001Cdk5\u306f\u4ed6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30ea\u30f3\u9178\u5316\u3059\u308b\u30ad\u30ca\u30fc\u30bc\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u30ea\u30f3\u9178\u5316\u3055\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u57fa\u8cea\uff09\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u8a73\u7d30\u306a\u5236\u5fa1\u306e\u4ed5\u7d44\u307f\u304c\u660e\u3089\u304b\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002
\n\u3053\u308c\u307e\u3067Cdk5\u3068\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u306e\u95a2\u9023\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u4f8b\u3048\u3070\u3001\u7d71\u5408\u5931\u8abf\u75c7\u306b\u304a\u3044\u3066Cdk5\u306e\u6a5f\u80fd\u4f4e\u4e0b\u3068\u306e\u95a2\u9023\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u540c\u75be\u60a3\u306b\u304a\u3044\u3066\u3082\u30b7\u30ca\u30d7\u30b9\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u304c\u3042\u308a\u3001Cdk5\u306e\u57fa\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u540c\u5b9a\u7b49\u3092\u901a\u3058\u3066\u3001\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u306e\u75c5\u614b\u306e\u89e3\u660e\u304c\u9032\u5c55\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<\/p>\n

(6) \u4eca\u5f8c\u306e\u8ab2\u984c<\/h4>\n

Cdk5\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u7d30\u80de\u3067\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3059\u308b\u85ac\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u52a9\u3051\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3001\u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u691c\u8a0e\u3055\u308c\u3066\u3044\u308b\u3002\u30b9\u30d1\u30a4\u30f3\u306e\u5f62\u6210\u30fb\u7dad\u6301\u306b\u95a2\u308f\u308b\u57fa\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u660e\u3089\u304b\u306b\u306a\u308c\u3070\u3001\u3088\u308a\u7279\u7570\u7684\u306a\u85ac\u5264\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u306e\u6cbb\u7642\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u4eca\u5f8c\u306f\u3001Cdk5\u306b\u3088\u308b\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u306e\u5236\u5fa1\u306e\u6a5f\u69cb\u3092\u8a73\u7d30\u306b\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u5fc5\u8981\u3067\u3042\u308b\u3068\u8003\u3048\u308b\u3002<\/p>\n

\u7528\u8a9e\u8aac\u660e<\/h4>\n

1. \u30b7\u30ca\u30d7\u30b9<\/h5>\n

\u795e\u7d4c\u7d30\u80de\u3069\u3046\u3057\u306e\u3064\u306a\u304e\u76ee\u306e\u3053\u3068\u3067\u3001\u30b7\u30ca\u30d7\u30b9\u3067\u7d50\u5408\u3057\u305f\u795e\u7d4c\u7d30\u80de\u304c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u3064\u304f\u3063\u3066\u3001\u795e\u7d4c\u56de\u8def\u3092\u5f62\u6210\u3059\u308b\u3002\u30b7\u30ca\u30d7\u30b9\u3067\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u524d\u90e8\u3067\u3042\u308b\u795e\u7d4c\u7d30\u80de\u306e\u8ef8\u7d22\u7d42\u672b\u304b\u3089\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306a\u3069\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u304c\u653e\u51fa\u3055\u308c\u3001\u30b7\u30ca\u30d7\u30b9\u5f8c\u90e8\u3067\u3042\u308b\u795e\u7d4c\u7d30\u80de\u306e\u30b9\u30d1\u30a4\u30f3\u304c\u3053\u308c\u3092\u53d7\u3051\u53d6\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u60c5\u5831\u304c\u4f1d\u9054\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

2. \u30b9\u30d1\u30a4\u30f3<\/h5>\n

\u795e\u7d4c\u7d30\u80de\u306e\u6a39\u72b6\u7a81\u8d77\u306b\u3042\u308b\u3068\u3052\u72b6\u306e\u69cb\u9020\u7269\u3002\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3092\u53d7\u3051\u53d6\u308b\u53d7\u5bb9\u4f53\u3084\u7d30\u80de\u5185\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306b\u95a2\u308f\u308b\u3055\u307e\u3056\u307e\u306a\u5206\u5b50\u304c\u96c6\u7a4d\u3057\u3066\u3044\u308b\u30b7\u30ca\u30d7\u30b9\u5f8c\u90e8\u306e\u7279\u6b8a\u306a\u69cb\u9020\u3067\u3042\u308b\u3002<\/p>\n

3. \u6d77\u99ac\uff08\u304b\u3044\u3070\uff09<\/h5>\n

\u7a7a\u9593\u5b66\u7fd2\u3084\u9577\u671f\u8a18\u61b6\u306e\u5f62\u6210\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3002\u6e7e\u66f2\u3057\u305f\u7d30\u9577\u3044\u69cb\u9020\u304c\u30bf\u30c4\u30ce\u30aa\u30c8\u30b7\u30b4\uff08\u30e9\u30c6\u30f3\u8a9e\u3067hippocampus\uff09\u306b\u4f3c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u6d77\u99ac\u3068\u540d\u4ed8\u3051\u3089\u308c\u305f\u3002CA1\u3001CA2\u3001CA3\u3001\u6b6f\u72b6\u56de\u306e\u5404\u9818\u57df\u306b\u795e\u7d4c\u7d30\u80de\u304c\u914d\u7f6e\u3055\u308c\u3001\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u5f62\u6210\u3057\u3066\u3044\u308b\u3002<\/p>\n

4. \u30e2\u30ea\u30b9\u6c34\u8ff7\u8def\u8a66\u9a13<\/h5>\n

\u30e2\u30ea\u30b9\u535a\u58eb\u304c\u8003\u6848\u3057\u305f\u3052\u3063\u6b6f\u985e\uff08\u30de\u30a6\u30b9\u3001\u30e9\u30c3\u30c8\uff09\u306e\u7a7a\u9593\u8a18\u61b6\u30fb\u5b66\u7fd2\u80fd\u529b\u3092\u5224\u5b9a\u3059\u308b\u65b9\u6cd5\u3002\u767d\u6fc1\u3057\u305f\u6c34\u3092\u306f\u3063\u305f\u5186\u5f62\u306e\u30d7\u30fc\u30eb\uff08\u76f4\u5f84 1m\uff09\u306b\u3001\u30de\u30a6\u30b9\u304c\u9019\u3044\u4e0a\u304c\u3063\u3066\u6c34\u304b\u3089\u9003\u308c\u3089\u308c\u308b\u30d7\u30e9\u30c3\u30c8\u30db\u30fc\u30e0\u3092\u6c34\u9762\u4e0b\u306b\u4f5c\u3063\u3066\u304a\u304f\u3002\u30de\u30a6\u30b9\u3092\u30d7\u30fc\u30eb\u306b\u5165\u308c\u30d7\u30e9\u30c3\u30c8\u30db\u30fc\u30e0\u306e\u5834\u6240\u3092\u3001\u30d7\u30fc\u30eb\u306e\u5468\u308a\u306e\u7a7a\u9593\u7684\u306a\u7269\u4f53\u306e\u914d\u7f6e\u304b\u3089\u5b66\u7fd2\u3055\u305b\u308b\u3002\u3053\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092 \uff17 \u65e5\u9593\u7a0b\u5ea6\u884c\u3063\u305f\u5f8c\u3001\u30d7\u30e9\u30c3\u30c8\u30db\u30fc\u30e0\u3092\u53d6\u308a\u9664\u3044\u305f\u72b6\u614b\u3067\u3001\u4e00\u5b9a\u6642\u9593\u5185\u306b\u30de\u30a6\u30b9\u304c\u3069\u308c\u3060\u3051\u30d7\u30e9\u30c3\u30c8\u30db\u30fc\u30e0\u304c\u5143\u3042\u3063\u305f\u5834\u6240\u3092\u63a2\u3059\u304b\u3069\u3046\u304b\u3092\u30c6\u30b9\u30c8\u3059\u308b\u3002<\/p>\n

\u8aac\u660e\u56f3<\/h4>\n

\u56f3\uff11\u3000<\/b>\u30b9\u30d1\u30a4\u30f3\u5f62\u6210\u524d\uff08\u4e0a\u6bb5\uff09\u3068\u30b9\u30d1\u30a4\u30f3\u5f62\u6210\u5f8c\u306bCdk5\u306e\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\uff08\u4e0b\u6bb5\uff09\u306e\u3044\u305a\u308c\u3082\u3067\u3001\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u304c\u89b3\u5bdf\u3055\u308c\u308b\u3002<\/p>\n

\"\u56f3\uff11\"<\/a><\/p>\n

\u56f3\uff12\u3000<\/b>\u6d77\u99acCA1\u9818\u57df\u7279\u7570\u7684\u306bCdk5\u306e\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8p35\u306e\u307f\uff08\u5de6\uff09\u3001p35\u3068p39\u306e\u4e21\u65b9\uff08\u53f3\uff09\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u306b\u3001\u6bb5\u968e\u7684\u306a\u30b9\u30d1\u30a4\u30f3\u5bc6\u5ea6\u306e\u4f4e\u4e0b\u304c\u307f\u3068\u3081\u3089\u308c\u305f\u3002<\/p>\n

\"\u56f3\uff12\"<\/a><\/p>\n

 <\/p>\n

\u56f3\uff13<\/b>\u3000\u6210\u4f53\u8133\u3067Cdk5\u306e\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8p35\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u306b\u3001\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u52b9\u7387\u306e\u4f4e\u4e0b\u3068\u30b7\u30ca\u30d7\u30b9\u9577\u671f\u6291\u5236\u8a98\u5c0e\u306e\u4f4e\u4e0b\u304c\u307f\u3089\u308c\u305f\u3002<\/p>\n

\"\u56f3\uff13\"<\/a><\/p>\n

\u56f3\uff14\u3000<\/b>\u30e2\u30ea\u30b9\u6c34\u8ff7\u8def\u8a66\u9a13\u306b\u3088\u308a\u3001\u6210\u4f53\u8133\u3067Cdk5\u306e\u6d3b\u6027\u5316\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8p35\u3092\u6b20\u640d\u3055\u305b\u305f\u5834\u5408\u306b\u306f\u3001\u7a7a\u9593\u5b66\u7fd2\uff08\u5de6\uff09\u3068\u7a7a\u9593\u8a18\u61b6\uff08\u53f3\uff09\u306e\u969c\u5bb3\u304c\u8d77\u304d\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3002<\/p>\n

\"\u56f3\uff14\"<\/a><\/p>\n

\u30ea\u30f3\u30af<\/h5>\n

\u65e9\u7a32\u7530\u5927\u5b66\u5148\u9032\u7406\u5de5\u5b66\u90e8\u751f\u547d\u533b\u79d1\u5b66\u79d1<\/a><\/p>\n

\u65e9\u7a32\u7530\u5927\u5b66\u5927\u5cf6\u767b\u5fd7\u7537\u7814\u7a76\u5ba4<\/a><\/p>\n

\u72ec\u7acb\u884c\u653f\u6cd5\u4eba\u7406\u5316\u5b66\u7814\u7a76\u6240\u8133\u79d1\u5b66\u7dcf\u5408\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u884c\u52d5\u907a\u4f1d\u5b66\u6280\u8853\u958b\u767a\u30c1\u30fc\u30e0<\/a><\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u7406\u5de5\u5b66\u8853\u9662\u30fb\u5927\u5cf6\u767b\u5fd7\u7537\u6559\u6388\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u8133\u5185\u3067\u795e\u7d4c\u7d30\u80de\u304c\u60c5\u5831\u4f1d\u9054\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u30b7\u30ca\u30d7\u30b9\uff08\u795e\u7d4c\u7d30\u80de\u540c\u58eb\u306e\u3064\u306a\u304e\u76ee\uff09\u3068\u3001\u305d\u306e\u4e00\u90e8\u3067\u3042\u308a\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3092\u53d7\u3051\u53d6\u308b\u5f79\u5272\u3092\u62c5\u3046\u30b9\u30d1\u30a4\u30f3\uff08\u795e\u7d4c\u7d30\u80de\u306e\u6a39\u72b6\u7a81\u8d77\u306b\u3042\u308b\u3068\u3052\u72b6\u306e\u69cb\u9020\u7269\uff09\u306e […]<\/p>\n","protected":false},"author":5,"featured_media":17032,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40,1],"tags":[53,5],"class_list":["post-16967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-topic","category-news","tag-health","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/16967","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/comments?post=16967"}],"version-history":[{"count":0,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/posts\/16967\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media\/17032"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/media?parent=16967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/categories?post=16967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/wp-json\/wp\/v2\/tags?post=16967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}