Exercise can have a positive impact on various aspects of human health. However, we have a limited understanding of the changes that exercise can induce at a molecular level. This is mainly due to the fact that earlier studies have typically involved invasive procedures like muscle biopsies. Now, researchers have introduced two emerging fields\u2013resistomics and enduromics\u2013that use \u201comics\u201d technologies to change our understanding of exercise-induced alterations in the body. <\/strong><\/p>\n Image title: From multi-omics to personalized training: Enduromics and resistomics Exercise has been recognized as an extremely effective tool to improve human health\u2014 it can have a preventative and even therapeutic effect on non-communicable diseases such as diabetes and cardiovascular diseases. By promoting physical activity not only among athletes, but also among the general population, several non-communicable diseases can be prevented, eventually reducing the financial burden upon the healthcare system. However, the exact changes that occur at a molecular level due to different types of exercise have not been explored thoroughly. One reason for this is that, traditionally, collecting molecular information (such as metabolite data) required invasive tissue or muscle biopsies, limiting the scale of studies that could be performed.<\/p>\n Now, in a study published in Volume 11 of the journal Sports Medicine – Open<\/em><\/a> on May 14, 2025, Dr. Kayvan Khoramipour from Miguel de Cervantes European University, along with other coauthors, and Professor Katsuhiko Suzuki from the Faculty of Sport Sciences, Waseda University, Japan, introduce and review literature in two emerging fields that could advance our understanding of exercise physiology in humans. These disciplines use \u2018multi-omics\u2019 data, or data from multiple sets of biological molecules (such as proteins, metabolites, or even RNA). Prof. Suzuki and his colleagues have termed these fields as \u2018resistomics<\/em>\u2019 and \u2018enduromics.<\/em>\u2019<\/p>\n The authors explain that \u2018enduromics<\/em>\u2019 and \u2018resistomics<\/em>\u2019 are fields that examine the molecular changes induced by endurance and resistance training, respectively. While endurance training is what we might refer to as aerobic exercise (that increases your breathing and heart rate), resistance training involves improving your muscle strength. To better explain these two terms, Prof. Suzuki further elaborates that, \u201cEnduromics<\/u> and resistomics<\/u> examine unique molecular adaptations to endurance and resistance training in a larger population, as opposed to the field of \u2018sportomics,\u2019 which focuses on molecular alterations in competitive athletes.\u201d<\/em><\/p>\n More specifically, enduromics <\/em>reveals the biological pathways involved in processes such as lipid metabolism, generation of new mitochondria, and aerobic efficiency, or your body\u2019s ability to effectively use oxygen\u2014all of which adapt and change in response to moderate-to-intense aerobic exercise. On the other hand, resistomics<\/em> specifically focuses on muscle hypertrophy or muscle growth, synthesis of new proteins, and neuromuscular adaptations in the body. These fields can identify the biomarkers and metabolic fingerprints, aiding in understanding how specific metabolic states differ between individuals. Taken together, both resistomics<\/em> and enduromics <\/em>can give us a clear picture of the molecular adaptations that arise in different individuals in response to both resistance and endurance training.<\/p>\n Emphasizing the practical applications of enduromics<\/em> and resistomics<\/em>, Prof. Suzuki explains, \u201cBy utilizing molecular profiling, these disciplines pave the way for personalized exercise prescriptions, using molecular insights to tailor training to an individual.\u201d <\/em>He adds that these personalized training plans can enhance fitness and rehabilitation while reducing injury risks for both athletes as well as the general population. The team also believes that by transitioning the focus from athletes to the general population, the collective health of society can be strengthened.<\/p>\n In the long term, Prof. Suzuki and his colleagues would like to discover molecular mechanisms underpinning adaptation to exercise, which could even prove helpful for disease prevention and treatment. We hope that enduromics<\/em> and resistomics<\/em> will pave the way for a new approach to exercise and public health!<\/p>\n About Professor Katsuhiko Suzuki<\/a> from Waseda University<\/strong><\/p>\n Dr. Katsuhiko Suzuki is currently a Professor in the Faculty of Sport Sciences at Waseda University. He completed both his M.D and Ph.D from the Hirosaki University School of Medicine. His research interests include exercise prescription for lifestyle-related diseases and risk assessment of acute and chronic exercise using biochemical and immunological variables. He has published more than 450 papers in the fields of exercise immunology, sports science, muscle damage, exercise biochemistry, and applied physiology, and has accumulated over 20,000 citations for the same, with a high h-index score of 74. He will hold a symposium of the International Society of Exercise Immunology as Chairman in Tokyo in late August 2026. To know more:<\/p>\n https:\/\/katsu.suzu.w.waseda.jp\/ISEI2026_Tokyo.html<\/a><\/p>\n Reference<\/strong><\/p>\n Title of original paper<\/strong>: From Multi-omics To Personalized Training: The Rise of Enduromics and Resistomics<\/a> Next-generation Fitness: New Fields That Promise Personalized Exercise Recommendations Emerging disciplines ar […]<\/p>\n","protected":false},"author":1,"featured_media":84917,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[81,117],"tags":[358,178],"class_list":["post-84897","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-topic","tag-pressrelease-en","tag-research-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/posts\/84897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/comments?post=84897"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/posts\/84897\/revisions"}],"predecessor-version":[{"id":84942,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/posts\/84897\/revisions\/84942"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/media\/84917"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/media?parent=84897"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/categories?post=84897"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/top\/en\/wp-json\/wp\/v2\/tags?post=84897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/www.waseda.jp\/top\/en\/assets\/uploads\/2025\/06\/Infographic_June_04_2025_Compressed-scaled.jpg\")
\nImage caption: Enduromics and resistomics are emerging disciplines that examine unique molecular adaptations to endurance and resistance training in a large population.
\nImage credit: Professor Katsuhiko Suzuki from Waseda University
\nLicense type: Original content
\nUsage restrictions: Cannot be reused without permission<\/p><\/div>\n
\nDOI<\/strong>:10.1186\/s40798-025-00855-4<\/a>
\nJournal<\/strong>: Sports Medicine – Open
\n<\/em>Article Publication Date<\/strong>: 14 May 2025
\nAuthors<\/strong><\/strong>: Kayvan Khoramipour1<\/sup>, Sergio Maroto-Izquierdo1<\/sup>, Simone Lista1<\/sup>, Alejandro Santos-Lozano1<\/sup>, and Katsuhiko Suzuki\u00b2
\n<\/sup>Affiliation<\/strong>:
\n1<\/sup>i+HeALTH Strategic Research Group, Department of Health Sciences,Miguel de Cervantes European University (UEMC), Spain
\n2<\/sup>Faculty of Sport Sciences, Waseda University, Japan<\/p>\n","protected":false},"excerpt":{"rendered":"