{"id":13013,"date":"2023-04-01T09:00:16","date_gmt":"2023-04-01T00:00:16","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/wias\/?p=13013"},"modified":"2024-04-03T16:16:15","modified_gmt":"2024-04-03T07:16:15","slug":"%e7%a7%8b%e5%b1%b1-%e5%be%b9-2-6-2-7","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/wias\/other\/2023\/04\/01\/13013\/","title":{"rendered":"\u661f\u540d \u76f4\u7950"},"content":{"rendered":"<h5>\u540d\u524d<\/h5>\n<p>\u661f\u540d \u76f4\u7950\uff08HOSHINA, Naosuke\uff09<\/p>\n<h5>\u53d6\u5f97\u5b66\u4f4d<\/h5>\n<p>\u535a\u58eb\uff08\u7406\u5b66\uff09<\/p>\n<h5>HP (URL)<\/h5>\n<p><a href=\"https:\/\/researchmap.jp\/nhoshina?lang=ja\">https:\/\/researchmap.jp\/nhoshina?lang=ja<\/a><\/p>\n<h5>\u8cc7\u683c<\/h5>\n<p>\u8b1b\u5e2b<\/p>\n<h5>\u7814\u7a76\u30c6\u30fc\u30de<\/h5>\n<p>\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u907a\u4f1d\u5b66\u7684\u89e3\u5256<\/p>\n<p style=\"text-align: justify;\">\u79c1\u305f\u3061\u304c\u611f\u3058\u3001\u8003\u3048\u3001\u884c\u52d5\u3059\u308b\u3053\u3068\u306f\u3001\u591a\u6570\u306e\u795e\u7d4c\u7d30\u80de\u304c\u8907\u96d1\u304b\u3064\u7cbe\u7dfb\u306b\u63a5\u7d9a\u3057\u3066\u3067\u304d\u308b\u300c\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u300d\u306b\u3088\u3063\u3066\u5b9f\u73fe\u3057\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u3069\u306e\u795e\u7d4c\u7d30\u80de\u540c\u58eb\u304c\u63a5\u7d9a\u3057\u3066\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u69cb\u7bc9\u3057\u3001\u69d8\u3005\u306a\u8133\u306e\u6a5f\u80fd\u3092\u767a\u63ee\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u3001\u672a\u3060\u89e3\u660e\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u79c1\u306f\u3001\u500b\u3005\u306e\u795e\u7d4c\u7d30\u80de\u304c\u6301\u3064\u907a\u4f1d\u5b50\u306e\u7279\u6027\u306b\u7740\u76ee\u3059\u308b\u3053\u3068\u3067\u3001\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u795e\u7d4c\u63a5\u7d9a\u30d1\u30bf\u30fc\u30f3\u3092\u89e3\u304d\u660e\u304b\u3057\u3001\u8133\u306e\u795e\u79d8\u306b\u8feb\u308a\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u308b\u3002<\/p>\n<h5>Monthly Spotlight<\/h5>\n<p>[Monthly Spotlight]\u306f\u7814\u7a76\u54e1\u306b\u30b9\u30dd\u30c3\u30c8\u3092\u3042\u3066\u3001\u7814\u7a76\u5185\u5bb9\u3068\u305d\u306e\u30d3\u30b8\u30e7\u30f3\u3092\u6bce\u6708\u7d39\u4ecb\u3057\u3066\u3044\u304f\u30b3\u30f3\u30c6\u30f3\u30c4\u3067\u3059\u3002<br \/>\n<a href=\"https:\/\/www.waseda.jp\/inst\/wias\/news\/2024\/02\/13\/15155\/\">\u8133\u306b\u304a\u3051\u308b\u30b7\u30ca\u30d7\u30b9\u63a5\u7740\u5206\u5b50\u306e\u6a5f\u80fd\u7684\u5f79\u5272\u3068\u7cbe\u795e\u30fb\u795e\u7d4c\u75be\u60a3\u3078\u306e\u95a2\u4e0e<\/a><\/p>\n<h5>\u7565\u6b74<\/h5>\n<p><strong>\u5b66\u6b74<\/strong><\/p>\n<table class=\"table table-striped table-chronology table-colored-tbhd\" style=\"width: 100%; border-collapse: collapse; height: 69px;\" border=\"0\">\n<tbody>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2009\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u6771\u4eac\u5927\u5b66 \u7406\u5b66\u7cfb\u7814\u7a76\u79d1 \u751f\u7269\u5316\u5b66\u5c02\u653b\uff08\u535a\u58eb\uff09<\/td>\n<\/tr>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2006\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u6771\u4eac\u5927\u5b66 \u7406\u5b66\u7cfb\u7814\u7a76\u79d1 \u751f\u7269\u5316\u5b66\u5c02\u653b\uff08\u4fee\u58eb\uff09<\/td>\n<\/tr>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2004\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u6771\u4eac\u5927\u5b66 \u7406\u5b66\u90e8 \u751f\u7269\u5316\u5b66\u79d1\uff08\u5b66\u58eb\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u8077\u6b74<\/strong><\/p>\n<table class=\"table table-striped table-chronology table-colored-tbhd\" style=\"width: 100%; border-collapse: collapse; height: 117px;\" border=\"0\">\n<tbody>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2023\u5e74-\u73fe\u5728<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u65e9\u7a32\u7530\u5927\u5b66 \u9ad8\u7b49\u7814\u7a76\u6240 \u8b1b\u5e2b<\/td>\n<\/tr>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2022\u5e74-2023\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u5343\u8449\u5927\u5b66 \u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662 \u7279\u4efb\u8b1b\u5e2b<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 17.1004%; height: 24px;\">2016\u5e74-2022\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 24px;\">\u30cf\u30fc\u30d0\u30fc\u30c9\u5927\u5b66 \u30dc\u30b9\u30c8\u30f3\u5c0f\u5150\u75c5\u9662 \u30ea\u30b5\u30fc\u30c1\u30d5\u30a7\u30ed\u30fc<\/td>\n<\/tr>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.1004%; height: 23px;\">2011\u5e742016\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 23px;\">\u6c96\u7e04\u79d1\u5b66\u6280\u8853\u5927\u5b66\u9662\u5927\u5b66 \u535a\u58eb\u7814\u7a76\u54e1<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 17.1004%; height: 24px;\">2009\u5e74-2011\u5e74<\/td>\n<td style=\"width: 82.8996%; height: 24px;\">\u6771\u4eac\u5927\u5b66 \u533b\u79d1\u5b66\u7814\u7a76\u6240 \u7279\u4efb\u7814\u7a76\u54e1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5>\u7814\u7a76\u9805\u76ee<\/h5>\n<p>\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3001\u795e\u7d4c\u56de\u8def\u3001\u795e\u7d4c\u7d30\u80de\u3001\u30b7\u30ca\u30d7\u30b9\u3001\u7d30\u80de\u63a5\u7740\u3001\u907a\u4f1d\u5b50\u6539\u5909\u30de\u30a6\u30b9<\/p>\n<h5>\u4e3b\u306a\u7814\u7a76\u696d\u7e3e<\/h5>\n<ul style=\"list-style-type: square;\">\n<li>\u661f\u540d \u76f4\u7950, \u6885\u68ee \u4e45\u8996<br \/>\n\u6d77\u99ac\u30b7\u30ca\u30d7\u30b9\u767a\u9054\u3068\u7cbe\u795e\u795e\u7d4c\u75be\u60a3\u3078\u306e\u95a2\u308f\u308a<br \/>\n\u751f\u4f53\u306e\u79d1\u5b66 (2023)<\/li>\n<li>Hoshina N, Johnson-Venkatesh EM, Rally V, Sant J, Hoshina M, Seiglie M, Umemori H.<br \/>\nASD\/OCD-linked Protocadherin-10 regulates synapse, but not axon, development in the amygdala and contributes to fear- and anxiety-related behaviors.<br \/>\nJ. Neurosci. (2022)<\/li>\n<li>Suzuki T, Hoshina M, Nishijima S, Hoshina N, Kikuguchi C, Tomohiro T, Fukao A, Fujiwara T, Yamamoto T.<br \/>\nRegulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2.<br \/>\nRNA Biol. (2022)<\/li>\n<li>Hoshina N, Johnson-Venkatesh EM, Hoshina M, Umemori H.<br \/>\nFemale-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder.<br \/>\nScience (2021)<\/li>\n<li>Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, Motohashi J, Pai EL, Pelkey KA, Pereira A, Philips T, Sinclair JL, Stogsdill JA, Traunm\u00fcller L, Wang J, Wortel J, You W, Abumaria N, Beier KT, Brose N, Burgess HA, Cepko CL, Cloutier JF, Eroglu C, Goebbels S, Kaeser PS, Kay JN, Lu W, Luo L, Mandai K, McBain CJ, Nave KA, Prado MAM, Prado VF, Rothstein J, Rubenstein JLR, Saher G, Sakimura K, Sanes JR, Scheiffele P, Takai Y, Umemori H, Verhage M, Yuzaki M, Zoghbi HY, Kawabe H, Craig AM.<br \/>\nOptimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.<br \/>\nNeuron (2020)<\/li>\n<li>Chang H#, Hoshina N#, Zhang C#, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Land\u00e9n M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, M\u00fcller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, N\u00f6then MM; Swedish Bipolar Study Group; MooDS Bipolar Consortium, Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M. (#: equally contributed)<br \/>\nThe protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.<br \/>\nMol. Psychiatry (2018)<\/li>\n<li>Ihara N, Nakashima A, Hoshina N, Ikegaya Y, Takeuchi H.<br \/>\nDifferential expression of axon-sorting molecules in mouse olfactory sensory neurons.<br \/>\nEur. J. Neurosci. (2016)<\/li>\n<li>Inoue T, Hoshina N, Nakazawa T, Kiyama Y, Kobayashi S, Abe T, Yamamoto T, Manabe T, Yamamoto T.<br \/>\nLMTK3 deficiency causes pronounced locomotor hyperactivity and impairs endocytic trafficking.<br \/>\nJ. Neurosci. (2014)<\/li>\n<li>\u661f\u540d \u76f4\u7950, \u5c71\u672c \u96c5<br \/>\n\u30d7\u30ed\u30c8\u30ab\u30c9\u30d8\u30ea\u30f317\u306f\u5927\u8133\u76ae\u8cea-\u5927\u8133\u57fa\u5e95\u6838\u795e\u7d4c\u56de\u8def\u306b\u304a\u3044\u3066\u524d\u30b7\u30ca\u30d7\u30b9\u306e\u69cb\u7bc9\u3092\u5236\u5fa1\u3059\u308b,<br \/>\n\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9 \u65b0\u7740\u8ad6\u6587\u30ec\u30d3\u30e5\u30fc (2013)<\/li>\n<li>Hoshina N, Tanimura A, Yamasaki M, Inoue T, Fukabori R, Kuroda T, Yokoyama K, Tezuka T, Sagara H, Hirano S, Kiyonari H, Takada M, Kobayashi K, Watanabe M, Kano M, Nakazawa T, Yamamoto T.<br \/>\nProtocadherin 17 regulates presynaptic assembly in topographic corticobasal ganglia circuits.<br \/>\nNeuron (2013)<\/li>\n<li>Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T.<br \/>\nNYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.<br \/>\nEMBO J. (2011)<\/li>\n<li>Hirota T, Kon N, Itagaki T, Hoshina N, Okano T, Fukada Y.<br \/>\nTranscriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork.<br \/>\nGenes Cells (2010)<\/li>\n<li>Hoshina N, Tezuka T, Yokoyama K, Kozuka-Hata H, Oyama M, Yamamoto T. Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth.<br \/>\nGenes Cells (2007)<\/li>\n<li>Yokoyama K, Tezuka T, Hoshina N, Nakazawa T, Yamamoto T.<br \/>\nPhosphorylation at Tyr-694 of Nogo-A by Src-family kinases.<br \/>\nBiochem. Biophys. Res. Commun. (2006)<\/li>\n<\/ul>\n<h5>\u8da3\u5473 \u95a2\u5fc3<\/h5>\n<p>\u97f3\u697d\uff08\u8074\u304f\u3001\u6b4c\u3046\u3001\u6f14\u594f\u3059\u308b\uff09\u3001\u5b50\u80b2\u3066<\/p>\n<h5>\u6240\u5c5e\u5b66\u4f1a<\/h5>\n<p>\u65e5\u672c\u795e\u7d4c\u79d1\u5b66\u5b66\u4f1a<br \/>\n\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u540d\u524d \u661f\u540d \u76f4\u7950\uff08HOSHINA, Naosuke\uff09 \u53d6\u5f97\u5b66\u4f4d \u535a\u58eb\uff08\u7406\u5b66\uff09 HP (URL) https:\/\/researchmap.jp\/nhoshina?lang=ja \u8cc7\u683c \u8b1b\u5e2b \u7814\u7a76\u30c6\u30fc\u30de \u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u907a [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":12928,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[96],"tags":[],"class_list":["post-13013","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/posts\/13013","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/comments?post=13013"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/posts\/13013\/revisions"}],"predecessor-version":[{"id":15666,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/posts\/13013\/revisions\/15666"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/media\/12928"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/media?parent=13013"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/categories?post=13013"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/wias\/wp-json\/wp\/v2\/tags?post=13013"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}