{"id":86278,"date":"2026-10-14T11:00:47","date_gmt":"2026-10-14T02:00:47","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=86278"},"modified":"2026-10-09T17:22:03","modified_gmt":"2026-10-09T08:22:03","slug":"%e7%b7%a8%e9%9b%86%e4%b8%ad-50","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/86278","title":{"rendered":"\u9ad8\u3044\u5fc3\u80ba\u4f53\u529b\u304c\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u308b\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u4e0a\u6607\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027"},"content":{"rendered":"<h2 style=\"text-align: center;\">\u9ad8\u3044\u5fc3\u80ba\u4f53\u529b\u304c\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u308b\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u4e0a\u6607\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027<\/h2>\n<h4>\u30dd\u30a4\u30f3\u30c8<\/h4>\n<ul>\n<li>\uf06c\u82f1\u56fd\u306e\u5927\u898f\u6a21\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u300cUK Biobank\u300d\u306b\u767b\u9332\u3055\u308c\u305f\u9589\u7d4c\u5f8c\u5973\u602715,199\u540d\u306e\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3001\u5fc3\u80ba\u4f53\u529b\u3068\u4e73\u304c\u3093\u306e\u591a\u907a\u4f1d\u5b50\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\uff08polygenic risk score\uff1aPRS\uff09\u304c\u5c06\u6765\u306e\u4e73\u304c\u3093\u767a\u75c7\u3068\u3069\u306e\u3088\u3046\u306b\u95a2\u9023\u3059\u308b\u304b\u3092\u691c\u8a0e\u3002<\/li>\n<li>10.7\u5e74\u9593\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u306b547\u540d\u304c\u4e73\u304c\u3093\u3092\u767a\u75c7\u3002\u5fc3\u80ba\u4f53\u529b\u304a\u3088\u3073PRS\u3068\u4e73\u304c\u3093\u767a\u75c7\u3068\u306e\u95a2\u9023\u3092\u500b\u5225\u306b\u89e3\u6790\u3057\u305f\u7d50\u679c\u3001\u9ad8\u3044\u5fc3\u80ba\u4f53\u529b\u306f\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3001\u9ad8\u3044PRS\u306f\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u4e0a\u6607\u3068\u95a2\u9023\u3002<\/li>\n<li>\uf06c\u5fc3\u80ba\u4f53\u529b\u3068PRS\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u4e73\u304c\u3093\u767a\u75c7\u3068\u306e\u95a2\u9023\u3092\u89e3\u6790\u3057\u305f\u7d50\u679c\u3001\u5fc3\u80ba\u4f53\u529b\u304c\u9ad8\u3044\u9589\u7d4c\u5f8c\u5973\u6027\u3067\u306f\u3001\u9ad8PRS\u306b\u4f34\u3046\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u306e\u4e0a\u6607\u304c\u5c0f\u3055\u3044\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3002<\/li>\n<\/ul>\n<h4>\u6982\u8981<\/h4>\n<p><a href=\"https:\/\/www.waseda.jp\/fsps\/\" target=\"_blank\" rel=\"noopener\">\u65e9\u7a32\u7530\u5927\u5b66\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u5b66\u8853\u9662<\/a>\u306e<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001823_ja.html\" target=\"_blank\" rel=\"noopener\">\u8c37\u6fa4 \u85ab\u5e73\uff08\u305f\u306b\u3055\u308f \u304f\u3093\u307a\u3044\uff09\u51c6\u6559\u6388<\/a>\u3001\u6e21\u9089 \u5927\u8f1d\uff08\u308f\u305f\u306a\u3079 \u3060\u3044\u304d\uff09\u62db\u8058\u7814\u7a76\u54e1\u3001\u897f\u5b89\u4ea4\u901a\u5927\u5b66\uff08\u4e2d\u56fd\uff09\u306e\u5b6b\u6681\u654f\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u82f1\u56fd\u306e\u5927\u898f\u6a21\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u300cUK Biobank\u300d<sup>\u203b1<\/sup>\u306b\u767b\u9332\u3055\u308c\u305f\u9589\u7d4c\u5f8c\u5973\u602715,199\u540d\u306e\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3001\u5fc3\u80ba\u4f53\u529b<sup>\u203b2<\/sup>\u304c\u9ad8\u3044\u9589\u7d4c\u5f8c\u5973\u6027\u3067\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u308b\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u306e\u4e0a\u6607\u304c\u5c0f\u3055\u3044\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u300e<a href=\"https:\/\/www.acsm.org\/education-resources\/journals\/medicine-science-in-sports-exercise\" target=\"_blank\" rel=\"noopener\">Medicine &amp; Science in Sports &amp; Exercise<\/a>\u300f\uff08\u8ad6\u6587\u540d\uff1aCardiorespiratory fitness, polygenic risk, and breast cancer in postmenopausal women: a prospective cohort study\uff09\u306b\u3066\u30012026\u5e7410\u67086\u65e5\uff08\u706b\uff09\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h4><strong>\uff08\uff11\uff09\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/strong><\/h4>\n<p>\u4e73\u304c\u3093\u306f\u5973\u6027\u306b\u304a\u3044\u3066\u4e16\u754c\u3067\u6700\u3082\u591a\u304f\u8a3a\u65ad\u3055\u308c\u308b\u304c\u3093\u3067\u3042\u308a\u3001\u305d\u306e\u767a\u75c7\u306b\u306f\u751f\u6d3b\u7fd2\u6163\u3001\u80a5\u6e80\u3001\u751f\u6b96\u30fb\u30db\u30eb\u30e2\u30f3\u95a2\u9023\u56e0\u5b50\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u4e73\u304c\u3093\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3082\u5f37\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790<sup>\u203b3<\/sup>\u306b\u3088\u308a\u4e73\u304c\u3093\u767a\u75c7\u3068\u95a2\u9023\u3059\u308b\u591a\u6570\u306e\u907a\u4f1d\u5b50\u591a\u578b\u304c\u540c\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3067\u306f\u3001\u3053\u308c\u3089\u591a\u6570\u306e\u907a\u4f1d\u5b50\u591a\u578b\u306e\u5f71\u97ff\u3092\u7d71\u5408\u3057\u305f\u591a\u907a\u4f1d\u5b50\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\uff08polygenic 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UK Biobank<\/p>\n<p>\u82f1\u56fd\u3067\u7d0450\u4e07\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u907a\u4f1d\u60c5\u5831\u3001\u751f\u6d3b\u7fd2\u6163\u3001\u8eab\u4f53\u6e2c\u5b9a\u5024\u3001\u75be\u60a3\u60c5\u5831\u306a\u3069\u3092\u9577\u671f\u7684\u306b\u53ce\u96c6\u3057\u3066\u3044\u308b\u5927\u898f\u6a21\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u3067\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u3053\u306e\u3046\u3061\u89e3\u6790\u6761\u4ef6\u3092\u6e80\u305f\u3057\u305f\u9589\u7d4c\u5f8c\u5973\u602715,199\u540d\u3092\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u203b2 \u5fc3\u80ba\u4f53\u529b\uff08cardiorespiratory fitness\uff1aCRF\uff09<\/p>\n<p>\u904b\u52d5\u6642\u306b\u9178\u7d20\u3092\u4f53\u5185\u306b\u53d6\u308a\u8fbc\u307f\u3001\u5168\u8eab\u306b\u904b\u642c\u3057\u3066\u5229\u7528\u3059\u308b\u80fd\u529b\u3092\u53cd\u6620\u3059\u308b\u4f53\u529b\u6307\u6a19\u3067\u3059\u3002\u5fc3\u81d3\u3001\u80ba\u3001\u8840\u7ba1\u3001\u9aa8\u683c\u7b4b\u306a\u3069\u306e\u6a5f\u80fd\u3092\u7dcf\u5408\u7684\u306b\u53cd\u6620\u3057\u3001\u6700\u5927\u9178\u7d20\u6442\u53d6\u91cf\uff08VO\u2082max\uff09\u306a\u3069\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u203b3 \u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790<\/p>\n<p>\u30d2\u30c8\u30b2\u30ce\u30e0\u5168\u4f53\u3092\u30ab\u30d0\u30fc\u3059\u308b\u6570\u5341\u4e07\u301c\u6570\u767e\u4e07\u306eSNP\u3068\u75be\u60a3\u30fb\u5f62\u8cea\u3068\u306e\u95a2\u9023\u3092\u7db2\u7f85\u7684\u306b\u691c\u8a0e\u3059\u308b\u907a\u4f1d\u7d71\u8a08\u89e3\u6790\u624b\u6cd5\u3067\u3059\u3002<\/p>\n<p>\u203b4 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&amp; Science in Sports &amp; Exercise<br \/>\n\u8ad6\u6587\u540d\uff1aCardiorespiratory fitness, polygenic risk, and breast cancer in postmenopausal women: a prospective cohort study<br \/>\n\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a<br \/>\n<a href=\"https:\/\/w-rdb.waseda.jp\/html\/100001823_ja.html\" target=\"_blank\" rel=\"noopener\">\u8c37\u6fa4 \u85ab\u5e73<\/a>\uff08\u65e9\u7a32\u7530\u5927\u5b66\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u5b66\u8853\u9662\uff09<br \/>\n\u6e21\u9089 \u5927\u8f1d\uff08\u65e9\u7a32\u7530\u5927\u5b66\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc, \u56fd\u7acb\u7814\u7a76\u958b\u767a\u6cd5\u4eba\u533b\u85ac\u57fa\u76e4\u30fb\u5065\u5eb7\u30fb\u6804\u990a\u7814\u7a76\u6240\uff09<br \/>\n\u674e \u5029\uff08\u897f\u5b89\u4ea4\u901a\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\uff09<br \/>\n\u6a0a \u590f\u73a5\uff08\u897f\u5b89\u4ea4\u901a\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\uff09<br \/>\n\u5b6b \u6681\u654f\uff08\u897f\u5b89\u4ea4\u901a\u5927\u5b66\uff09<br \/>\n\u63b2\u8f09\u65e5\u6642\uff1a2026\u5e7410\u67086\u65e5\uff08\u706b\uff09\uff08\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\uff09<br \/>\n\u63b2\u8f09URL\uff1a<br \/>\n<a href=\"https:\/\/www.ovid.com\/jnls\/acsm-msse\/fulltext\/10.1249\/mss.0000000000004164~cardiorespiratory-fitness-polygenic-risk-and-breast-cancer\" target=\"_blank\" rel=\"noopener\">https:\/\/www.ovid.com\/jnls\/acsm-msse\/fulltext\/10.1249\/mss.0000000000004164~cardiorespiratory-fitness-polygenic-risk-and-breast-cancer<\/a><br \/>\nDOI\uff1a10.1249\/MSS.0000000000004164<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9ad8\u3044\u5fc3\u80ba\u4f53\u529b\u304c\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u308b\u4e73\u304c\u3093\u767a\u75c7\u30ea\u30b9\u30af\u4e0a\u6607\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027 \u30dd\u30a4\u30f3\u30c8 \uf06c\u82f1\u56fd\u306e\u5927\u898f\u6a21\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u300cUK 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