{"id":85269,"date":"2026-04-15T15:33:25","date_gmt":"2026-04-15T06:33:25","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=85269"},"modified":"2026-07-15T15:33:38","modified_gmt":"2026-07-15T06:33:38","slug":"adaptive-4d-printed-vascular-stents-with-low-temperature-activated-and-intelligent-deployment%ef%bc%88published-in-advanced-functional-materials-april-2026%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/85269","title":{"rendered":"Adaptive 4D-Printed Vascular Stents With Low-Temperature-Activated and Intelligent Deployment\uff08Published in Advanced Functional Materials, April, 2026\uff09"},"content":{"rendered":"<table class=\"table table-bordered table-colored-tbhd\" style=\"height: 636px; width: 100%; border-collapse: collapse; border-style: solid;\" border=\"1\">\n<tbody>\n<tr style=\"height: 78px;\">\n<td style=\"width: 18.9673%; height: 78px;\">Journal Title<br \/>\n\/\u63b2\u8f09\u30b8\u30e3\u30fc\u30ca\u30eb\u540d<\/td>\n<td style=\"width: 80.934%; height: 78px;\">Advanced Functional Materials<\/td>\n<\/tr>\n<tr style=\"height: 65px;\">\n<td style=\"width: 18.9673%; height: 80px;\">Publication Year and Month<br \/>\n\/\u63b2\u8f09\u5e74\u6708<\/td>\n<td style=\"width: 80.934%; height: 80px;\">April, 2026<\/td>\n<\/tr>\n<tr style=\"height: 55px;\">\n<td style=\"width: 18.9673%; height: 79px;\">Paper Title<br \/>\n\/\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/td>\n<td style=\"width: 80.934%; height: 79px;\">Adaptive 4D-Printed Vascular Stents With Low-Temperature-Activated and Intelligent Deployment<\/td>\n<\/tr>\n<tr style=\"height: 85px;\">\n<td style=\"width: 18.9673%; height: 85px;\">DOI<br \/>\n\/\u8ad6\u6587DOI<\/td>\n<td style=\"width: 80.934%; height: 85px;\"><a href=\"https:\/\/doi.org\/10.1002\/adfm.202521468\">10.1002\/adfm.202521468<\/a><\/td>\n<\/tr>\n<tr style=\"height: 59px;\">\n<td style=\"width: 18.9673%; height: 80px;\">\u00a0Author of Waseda University<br \/>\n\/\u672c\u5b66\u306e\u8457\u8005<\/td>\n<td style=\"width: 80.934%; height: 80px;\"><span style=\"font-family: inherit; font-size: inherit;\"><span style=\"font-family: inherit; font-size: inherit;\">UMEZU, Shinjiro(Professor, Faculty of Science and Engineering, School of Creative Science and Engineering):Correspoinding Author<\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 68px;\">\n<td style=\"width: 18.9673%; height: 86px;\">Related Websites<br \/>\n\/\u95a2\u9023Web<\/td>\n<td style=\"width: 80.934%; height: 86px;\">&#8211;<\/td>\n<\/tr>\n<tr style=\"height: 138px;\">\n<td style=\"width: 18.9673%; height: 148px;\">Abstract<br \/>\n\/\u6284\u9332<\/td>\n<td style=\"width: 80.934%; height: 148px;\">\n<div id=\"abstractBox\">\n<section id=\"abs-sec-1\">The development of patient-specific, adaptively deployable vascular stents is crucial for advancing minimally invasive cardiovascular therapies. Here, we report the fabrication of microarchitected coronary artery stents via projection micro-stereolithography (P\u00b5SL) 4D printing using a polycaprolactone (PCL)-based shape memory polymer (SMP) composite. By incorporating diethyl phthalate (DEP) as a plasticizer, we precisely modulated the thermal transition temperature (T<sub>tran<\/sub>) to about 37\u00b0C, enabling rapid and autonomous shape recovery under physiological conditions without external heating. The resulting stents exhibit a favorable balance between mechanical flexibility and strength. Finite element simulations validated the uniform stress distribution and structural robustness. A viscoelastic stress relaxation model confirmed the ability of the stents to dissipate internal stress over time, promoting long-term biomechanical compliance. In vitro studies demonstrated excellent cytocompatibility. In vivo implantation experiments in mice further confirmed the possibility of clinical application. Overall, this work provides a robust platform for adaptive vascular stents with programmable thermoresponsive behavior and intelligent deployment, offering significant potential for personalized treatment in anatomically complex vascular structures.<\/section>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Journal Title \/\u63b2\u8f09\u30b8\u30e3\u30fc\u30ca\u30eb\u540d Advanced Functional Materials Publication Year and Month \/\u63b2\u8f09\u5e74\u6708 April, 2026 Paper Title [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[218,217],"class_list":["post-85269","post","type-post","status-publish","format-standard","hentry","tag-impact-en","tag-impact"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/85269","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/comments?post=85269"}],"version-history":[{"count":1,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/85269\/revisions"}],"predecessor-version":[{"id":85271,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/85269\/revisions\/85271"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media?parent=85269"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/categories?post=85269"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/tags?post=85269"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}