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distasonis\u306e\u5897\u52a0\u3068\u3068\u3082\u306b\u3001\u4ee3\u8b1d\u7269\u3067\u3042\u308b\u30b3\u30cf\u30af\u9178\u306e\u7523\u751f\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u3053\u306e\u30b3\u30cf\u30af\u9178\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306e\u9375\u3068\u306a\u308b\u80a5\u6e80\u7d30\u80de\u306e\u6d3b\u6027\u5316\uff08\u8131\u9846\u7c92\uff09\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u75c7\u72b6\u306e\u6307\u6a19\u306e\u4e00\u3064\u3067\u3042\u308b\u4f53\u6e29\u4f4e\u4e0b\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<br 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\/>\n\u672c\u7814\u7a76\u6210\u679c\u306f\u30012026\u5e745\u670812\u65e5\uff08\u82f1\u56fd\u6a19\u6e96\u6642\uff09\u306b\u56fd\u969b\u5b66\u8853\u8a8c\u300eNature Microbiology\u300f\uff08\u96fb\u5b50\u7248\uff09\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h3>\u7814\u7a76\u6210\u679c\u306e\u30dd\u30a4\u30f3\u30c8<\/h3>\n<p>\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306e\u6295\u4e0e\u306b\u3088\u308a\u3001\u4ee5\u4e0b\u3001\u2460\uff5e\u2464\u306e\u5b9f\u9a13\u7d50\u679c\u306e\u3082\u3068\u80a5\u6e80\u7d30\u80de\u306e\u6d3b\u6027\u5316\uff08\u8131\u9846\u7c92\uff09\u3092\u6291\u5236\u3057\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306b\u4f34\u3046\u4f53\u6e29\u4f4e\u4e0b\u306e\u8efd\u6e1b\u3092\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<br \/>\n\u2460 \u8178\u5185\u7d30\u83cc\u53e2\u304c\u5909\u5316\u3057\u3001P. distasonis\u306e\u5897\u52a0\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002<br \/>\n\u2461 \u8178\u5185\u306e\u30b3\u30cf\u30af\u9178\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u30b3\u30cf\u30af\u9178\u306f\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3059\u308b\u3002<br \/>\n\u2462\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306e\u4f5c\u7528\u306b\u306f\u3001\u30b9\u30af\u30ed\u30fc\u30b9\u3084\u30de\u30eb\u30c8\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306a\u3069\u306e\u6d88\u5316\u6027\u591a\u7cd6\u304c\u5927\u8178\u3078\u5230\u9054\u3059\u308b\u3053\u3068\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<br \/>\n\u2463\u6d88\u5316\u6027\u591a\u7cd6\u304c\u5b58\u5728\u3059\u308b\u6761\u4ef6\u3067\u306f\u3001P. distasonis\u306f\u5acc\u6c17\u547c\u5438<sup>\u203b2<\/sup>\u304b\u3089\u767a\u9175<sup>\u203b3<\/sup>\u578b\u4ee3\u8b1d\u3078\u79fb\u884c\u3057\u3001\u5897\u6b96\u304a\u3088\u3073\u30b3\u30cf\u30af\u9178\u7523\u751f\u304c\u4fc3\u9032\u3055\u308c\u308b\u3002<br \/>\n\u2464\u533b\u7642\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u3088\u308a\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u3092\u7d99\u7d9a\u7684\u306b\u670d\u7528\u3057\u3066\u3044\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u306f\u3001\u975e\u670d\u7528\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u983b\u5ea6\u304c\u4f4e\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u308b\u3002<\/p>\n<div id=\"attachment_84306\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84306 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-610x384.png\" alt=\"\" width=\"610\" height=\"384\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-610x384.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-940x592.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-768x483.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-1536x967.png 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/29d3bc99193cb0b837fb8cc53f050ae5-1-2048x1289.png 2048w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f31. \u672c\u7814\u7a76\u306e\u6982\u5ff5\u56f3 (\u2160)<\/strong><br \/>\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u306b\u3088\u308a\u3001\u5c0f\u8178\u3067\u5206\u89e3\u30fb\u5438\u53ce\u3055\u308c\u306a\u304b\u3063\u305f\u30b9\u30af\u30ed\u30fc\u30b9\u3084\u30de\u30eb\u30c8\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u304c\u5927\u8178\u306b\u5230\u9054\u3057\u3001\u8178\u5185\u7d30\u83cc\u306b\u5229\u7528\u3055\u308c\u308b\u3002(\u2161)\u5927\u8178\u3067\u306fP. distasonis\u304c\u5897\u52a0\u3057\u3001\u7cd6\u304c\u8c4a\u5bcc\u306a\u74b0\u5883\u3067\u5acc\u6c17\u547c\u5438\u304b\u3089\u767a\u9175\u578b\u4ee3\u8b1d\u3078\u79fb\u884c\u3059\u308b\u3053\u3068\u3067\u3001\u5897\u6b96\u3068\u30b3\u30cf\u30af\u9178\u7523\u751f\u304c\u4fc3\u9032\u3055\u308c\u308b\u3002\u7523\u751f\u3055\u308c\u305f\u30b3\u30cf\u30af\u9178\u306f\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3057\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u3002(\u2162)\u3055\u3089\u306b\u3001\u533b\u7642\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u3088\u308a\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u306f\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u983b\u5ea6\u304c\u4f4e\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/p><\/div>\n<h3>\u7814\u7a76\u306e\u80cc\u666f<\/h3>\n<p>\u306f\u3058\u3081\u306b\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u304c\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u5375\u767d\u30a2\u30eb\u30d6\u30df\u30f3\uff08ovalbumin: OVA\uff09\u306b\u5bfe\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u5fdc\u7b54\u3092\u8a98\u5c0e\u3057\u305f\u30de\u30a6\u30b9\u3092\u4f5c\u88fd\u3057\u307e\u3057\u305f\u3002\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u3092\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u306bOVA\u3092\u53cd\u5fa9\u7d4c\u53e3\u6295\u4e0e\u3057\u3066\u4e0b\u75e2\u3092\u8a98\u5c0e\u3057\u3001\u3055\u3089\u306b\u8179\u8154\u5185\u6295\u4e0e\u306b\u3088\u308a\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u3092\u8a98\u767a\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u7fa4\u3067\u306f\u3001\u4e0b\u75e2\u306e\u767a\u75c7\u983b\u5ea6\u304a\u3088\u3073\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306b\u4f34\u3046\u4f53\u6e29\u4f4e\u4e0b\u304c\u3044\u305a\u308c\u3082\u6291\u5236\u3055\u308c\u307e\u3057\u305f\uff08\u56f32A\u3001B\uff09\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306e\u4e2d\u5fc3\u7684\u5f79\u5272\u3092\u62c5\u3046\u80a5\u6e80\u7d30\u80de\u306e\u6d3b\u6027\u5316\uff08\u8131\u9846\u7c92\uff09\u306b\u3064\u3044\u3066\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u3067\u89e3\u6790\u3057\u305f\u7d50\u679c\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u7fa4\u3067\u306f\u8131\u9846\u7c92\u3057\u305f\u80a5\u6e80\u7d30\u80de\u306e\u5272\u5408\u304c\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f32C\uff09\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u4f34\u3046\u4e0b\u75e2\u304a\u3088\u3073\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84307\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84307 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/5e4896966c9944fcf00890f4502605bf-610x166.png\" alt=\"\" width=\"610\" height=\"166\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/5e4896966c9944fcf00890f4502605bf-610x166.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/5e4896966c9944fcf00890f4502605bf-940x256.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/5e4896966c9944fcf00890f4502605bf-768x209.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/5e4896966c9944fcf00890f4502605bf.png 1386w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f32. \u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b<\/strong><br \/>\uff08A\uff09\u4e0b\u75e2\u306e\u767a\u75c7\u983b\u5ea6\u3002<br \/>\uff08B\uff09\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306e\u4f53\u6e29\u5909\u5316\u3002<br \/>\uff08C\uff09\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306b\u304a\u3051\u308b\u8131\u9846\u7c92\u80a5\u6e80\u7d30\u80de\u306e\u5272\u5408\u3002<\/p><\/div>\n<p>\u6b21\u306b\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u6291\u5236\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u3001\u65e2\u77e5\u306e\u514d\u75ab\u8abf\u7bc0\u56e0\u5b50\u306b\u3064\u3044\u3066\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u5fdc\u7b54\u3092\u4fc3\u9032\u3059\u308b2\u578b\u30d8\u30eb\u30d1\u30fcT\u7d30\u80de\u306e\u5272\u5408\u306f\u3001\u8907\u6570\u306e\u7d44\u7e54\u306b\u304a\u3044\u3066\u5bfe\u7167\u7fa4\u3068\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u7fa4\u3067\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f33A\uff09\u3002\u4e00\u65b9\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u306b\u3088\u308aIgA\u7523\u751fB\u7d30\u80de\u306e\u5272\u5408\u304a\u3088\u3073\u8840\u6e05\u4e2d\u306eOVA\u7279\u7570\u7684IgA\u30ec\u30d9\u30eb\u304c\u4e0a\u6607\u3057\u307e\u3057\u305f\uff08\u56f33B\uff09\u3002IgA\u306fIgE\u3068\u6297\u539f\u306e\u7d50\u5408\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001IgA\u6b20\u640d\u30de\u30a6\u30b9\u3092\u7528\u3044\u3066\u691c\u8a3c\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001IgA\u6b20\u640d\u6761\u4ef6\u306b\u304a\u3044\u3066\u3082\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306b\u4f34\u3046\u4f53\u6e29\u4f4e\u4e0b\u3092\u6291\u5236\u3057\u307e\u3057\u305f\uff08\u56f33C\uff09\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306b\u3088\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u6291\u5236\u52b9\u679c\u306f\u3001\u5f93\u6765\u60f3\u5b9a\u3055\u308c\u3066\u3044\u305f\u514d\u75ab\u56e0\u5b50\u306b\u4f9d\u5b58\u3057\u306a\u3044\u7d4c\u8def\u306b\u3088\u3063\u3066\u767a\u63ee\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84308\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84308 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/1efad1b5aa917a846fa5b3fc11367269-610x385.png\" alt=\"\" width=\"610\" height=\"385\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/1efad1b5aa917a846fa5b3fc11367269-610x385.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/1efad1b5aa917a846fa5b3fc11367269-940x593.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/1efad1b5aa917a846fa5b3fc11367269-768x484.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/1efad1b5aa917a846fa5b3fc11367269.png 1292w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f33. \u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306b\u3088\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u6291\u5236\u306f\u5f93\u6765\u306e\u514d\u75ab\u56e0\u5b50\u306b\u4f9d\u5b58\u3057\u306a\u3044<\/strong><br \/>\uff08A\uff09\u5404\u7a2e\u7d44\u7e54\u306b\u304a\u3051\u308b2\u578b\u30d8\u30eb\u30d1\u30fcT\u7d30\u80de\u306e\u5272\u5408\u3002<br \/>\uff08B\uff09IgA\u5206\u6cccB\u7d30\u80de\u306e\u5272\u5408\u304a\u3088\u3073\u8840\u6e05\u4e2d\u306e\u6297\u539f\u7279\u7570\u7684IgA\u30ec\u30d9\u30eb\u3002<br \/>\uff08C\uff09IgA\u6b20\u640d\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306e\u4f53\u6e29\u5909\u5316\u3002<\/p><\/div>\n<p>\u6b21\u306b\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306b\u3088\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u6291\u5236\u4f5c\u7528\u304c\u8178\u5185\u7d30\u83cc\u53e2\u306b\u4f9d\u5b58\u3059\u308b\u304b\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u6297\u83cc\u5264\u6295\u4e0e\u4e0b\u3067\u6bd4\u8f03\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u6297\u83cc\u5264\u6295\u4e0e\u6761\u4ef6\u3067\u306f\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306b\u4f34\u3046\u4f53\u6e29\u4f4e\u4e0b\u3092\u6291\u5236\u3057\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f34A\uff09\u3002\u305d\u3053\u3067\u3001\u95a2\u4e0e\u3059\u308b\u8178\u5185\u7d30\u83cc\u3092\u540c\u5b9a\u3059\u308b\u305f\u308116S ribosomal RNA\u907a\u4f1d\u5b50\u89e3\u6790<sup>\u203b4<\/sup>\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u7fa4\u3067\u306f Parabacteroides \u5c5e\u7d30\u83cc\u304c\u5897\u52a0\u3057\u3001\u7279\u306b P. distasonis \u306e\u5897\u52a0\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\uff08\u56f34B\u3001C\uff09\u3002\u3055\u3089\u306b\u3001\u7121\u83cc\u30de\u30a6\u30b9\u306b P. distasonis \u3092\u5b9a\u7740\u3055\u305b\u3066\u691c\u8a3c\u3057\u305f\u7d50\u679c\u3001\u4f53\u6e29\u4f4e\u4e0b\u304c\u8efd\u6e1b\u3055\u308c\u307e\u3057\u305f\uff08\u56f34D\uff09\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f P. distasonis \u306e\u5897\u52a0\u3092\u4ecb\u3057\u3066\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84309\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84309 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7d6fddc4d5f4457e598413974089fe73-610x177.png\" alt=\"\" width=\"610\" height=\"177\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7d6fddc4d5f4457e598413974089fe73-610x177.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7d6fddc4d5f4457e598413974089fe73-940x273.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7d6fddc4d5f4457e598413974089fe73-768x223.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7d6fddc4d5f4457e598413974089fe73.png 1386w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f34. \u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f P. distasonis \u306e\u5897\u52a0\u3092\u4ecb\u3057\u3066\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u3092\u6291\u5236\u3059\u308b<\/strong><br \/>\uff08A\uff09\u6297\u83cc\u5264\u6295\u4e0e\u6761\u4ef6\u306b\u304a\u3051\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306e\u4f53\u6e29\u5909\u5316\u3002<br \/>\uff08B\uff0916S rRNA\u907a\u4f1d\u5b50\u89e3\u6790\u306b\u3088\u308a\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u3067\u6709\u610f\u306b\u5909\u52d5\u3057\u305f\u7d30\u83cc\u306e\u3046\u3061\u4e0a\u4f4d15\u5c5e\u3092\u8868\u793a\u3002<br \/>\uff08C\uff09\u5168\u957716S rRNA\u907a\u4f1d\u5b50\u89e3\u6790\u306b\u3088\u308b\u7d30\u83cc\u7d44\u6210\u306e\u5909\u5316\u3002<br \/>\uff08D\uff09\u7121\u83cc\u30de\u30a6\u30b9\u304a\u3088\u3073 P. distasonis \u5b9a\u7740\u30de\u30a6\u30b9\u306b\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u3092\u6295\u4e0e\u3057\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306e\u4f53\u6e29\u4f4e\u4e0b\u3092\u6bd4\u8f03\u3002\u7121\u83cc\u30de\u30a6\u30b9\u975e\u6295\u4e0e\u7fa4\u306e\u6700\u5927\u4f53\u6e29\u4f4e\u4e0b\u3092\u57fa\u6e96\u3068\u3057\u305f\u5dee\u5206\u3092\u793a\u3059\u3002<\/p><\/div>\n<p>\u6b21\u306b\u3001\u8178\u5185\u7d30\u83cc\u7531\u6765\u4ee3\u8b1d\u7269\u306e\u95a2\u4e0e\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u3001\u30e1\u30bf\u30dc\u30ed\u30fc\u30e0\u89e3\u6790<sup>\u203b5<\/sup>\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u7fa4\u3067\u306f\u30b3\u30cf\u30af\u9178\u6fc3\u5ea6\u304c\u9855\u8457\u306b\u4e0a\u6607\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f35A\uff09\u3002\u30b3\u30cf\u30af\u9178\u306e\u5897\u52a0\u306f\u6297\u83cc\u5264\u6295\u4e0e\u6761\u4ef6\u3067\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u8178\u5185\u7d30\u83cc\u7531\u6765\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\uff08\u56f35B\uff09\u3002\u6b21\u306b\u3001\u30b3\u30cf\u30af\u9178\u306e\u6a5f\u80fd\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u30de\u30a6\u30b9\u306b\u30b3\u30cf\u30af\u9178\u3092\u98f2\u6c34\u6295\u4e0e\u3057\u3066\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u3092\u8a98\u5c0e\u3057\u307e\u3057\u305f\u3002\u30b3\u30cf\u30af\u9178\u6295\u4e0e\u306b\u3088\u308a\u4f53\u6e29\u4f4e\u4e0b\u306e\u6291\u5236\u304a\u3088\u3073\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u6291\u5236\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\uff08\u56f35C\u3001D\uff09\u3002\u3055\u3089\u306b\u3001\u751f\u4f53\u5916\u57f9\u990a\u7cfb<sup>\u203b6<\/sup>\u306b\u304a\u3044\u3066\u3082\u3001\u30b3\u30cf\u30af\u9178\u306f\u6fc3\u5ea6\u4f9d\u5b58\u7684\u306b\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3057\u307e\u3057\u305f\uff08\u56f35E\uff09\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u306f\u8178\u5185\u306b\u304a\u3051\u308b\u30b3\u30cf\u30af\u9178\u7523\u751f\u3092\u5897\u52a0\u3055\u305b\u3001\u30b3\u30cf\u30af\u9178\u304c\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306e\u7de9\u548c\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84310\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84310 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7adfed136bf50c6b1f5c23f5919c3a0a-610x451.png\" alt=\"\" width=\"610\" height=\"451\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7adfed136bf50c6b1f5c23f5919c3a0a-610x451.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7adfed136bf50c6b1f5c23f5919c3a0a-940x694.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7adfed136bf50c6b1f5c23f5919c3a0a-768x567.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/7adfed136bf50c6b1f5c23f5919c3a0a.png 1386w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f35. \u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u306b\u3088\u308a\u5897\u52a0\u3057\u305f\u30b3\u30cf\u30af\u9178\u306f\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3057\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u3092\u8efd\u6e1b\u3059\u308b<\/strong><br \/>\uff08A\uff09\u30e1\u30bf\u30dc\u30ed\u30fc\u30e0\u89e3\u6790\u306b\u3088\u308b\u4ee3\u8b1d\u7269\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3002<br \/>\uff08B\uff09\u7cde\u4fbf\u4e2d\u30b3\u30cf\u30af\u9178\u6fc3\u5ea6\u3002<br \/>\uff08C\uff09\u30b3\u30cf\u30af\u9178\u6295\u4e0e\u5f8c\u306e\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u306b\u4f34\u3046\u4f53\u6e29\u5909\u5316\u3002<br \/>\uff08D\uff09\u30b3\u30cf\u30af\u9178\u6295\u4e0e\u5f8c\u306b\u304a\u3051\u308b\u8131\u9846\u7c92\u80a5\u6e80\u7d30\u80de\u306e\u5272\u5408\u3002<br \/>\uff08E\uff09\u751f\u4f53\u5916\u57f9\u990a\u7cfb\u306b\u304a\u3051\u308b\u30b3\u30cf\u30af\u9178\u66dd\u9732\u4e0b\u3067\u306e\u8131\u9846\u7c92\u80a5\u6e80\u7d30\u80de\u306e\u5272\u5408\u3002<\/p><\/div>\n<p>\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u5c0f\u8178\u306b\u304a\u3051\u308b\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u304a\u3088\u3073\u03b1-\u30a2\u30df\u30e9\u30fc\u30bc\u3092\u963b\u5bb3\u3057\u3001\u672a\u6d88\u5316\u306e\u7cd6\u8cea\uff08\u30b9\u30af\u30ed\u30fc\u30b9\u3084\u30de\u30eb\u30c8\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306a\u3069\uff09\u3092\u5927\u8178\u3078\u5230\u9054\u3055\u305b\u3001\u8178\u5185\u7d30\u83cc\u306b\u3088\u308b\u5229\u7528\u3092\u4fc3\u9032\u3057\u307e\u3059\uff08\u56f36A\uff09\u3002\u305d\u3053\u3067\u3001\u5927\u8178\u3078\u306e\u7cd6\u4f9b\u7d66\u306e\u5fc5\u8981\u6027\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u98fc\u6599\u4e2d\u306e\u7cd6\u3092\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u7f6e\u63db\u3057\u305f\u30b0\u30eb\u30b3\u30fc\u30b9\u98fc\u6599\u3092\u7528\u3044\u307e\u3057\u305f\u3002\u30b0\u30eb\u30b3\u30fc\u30b9\u306f\u5c0f\u8178\u3067\u901f\u3084\u304b\u306b\u5438\u53ce\u3055\u308c\u308b\u305f\u3081\u3001\u5927\u8178\u3078\u306e\u7cd6\u4f9b\u7d66\u306f\u307b\u3068\u3093\u3069\u8d77\u3053\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u6761\u4ef6\u3067\u306f\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u6295\u4e0e\u306f\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306b\u4f34\u3046\u4f53\u6e29\u4f4e\u4e0b\u304a\u3088\u3073\u80a5\u6e80\u7d30\u80de\u306e\u8131\u9846\u7c92\u3092\u6291\u5236\u3057\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f36B\u3001C\uff09\u3002\u3055\u3089\u306b\u3001\u901a\u5e38\u98fc\u6599\u3067\u8a8d\u3081\u3089\u308c\u305f Parabacteroides \u5c5e\u7d30\u83cc\u306e\u5897\u52a0\u3082\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u56f36D\uff09\u3002\u6b21\u306b\u3001\u7cd6\u304c\u7d30\u83cc\u5897\u6b96\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u691c\u8a3c\u3057\u305f\u7d50\u679c\u3001\u30b9\u30af\u30ed\u30fc\u30b9\u304a\u3088\u3073\u30de\u30eb\u30c8\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3092\u6dfb\u52a0\u3057\u305f\u57f9\u5730\u3067\u306f\u3001P. distasonis \u306e\u5897\u6b96\u304c\u4fc3\u9032\u3055\u308c\u307e\u3057\u305f\uff08\u56f36E\uff09\u3002\u3055\u3089\u306b\u3001\u7d30\u83cc\u5185\u306e\u4ee3\u8b1d\u72b6\u614b\u3092\u89e3\u6790\u3059\u308b\u305f\u3081\u30e9\u30de\u30f3\u5206\u5149\u6cd5<sup>\u203b7<\/sup>\u3092\u9069\u7528\u3057\u307e\u3057\u305f\u3002\u30b9\u30af\u30ed\u30fc\u30b9\u304a\u3088\u3073\u30de\u30eb\u30c8\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u5b58\u5728\u4e0b\u3067\u306f\u3001\u5acc\u6c17\u547c\u5438\u306b\u95a2\u4e0e\u3059\u308bb\u578b\u30b7\u30c8\u30af\u30ed\u30fc\u30e0\u306e\u91cf\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f36F\uff09\u3002b\u578b\u30b7\u30c8\u30af\u30ed\u30fc\u30e0\u306f\u5916\u90e8\u96fb\u5b50\u53d7\u5bb9\u4f53\u3092\u7528\u3044\u308b\u547c\u5438\u9396\u306e\u69cb\u6210\u8981\u7d20\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u3053\u306e\u4f4e\u4e0b\u306f\u5acc\u6c17\u547c\u5438\u306e\u6d3b\u6027\u304c\u6291\u5236\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u4ee3\u8b1d\u304c\u5916\u90e8\u96fb\u5b50\u53d7\u5bb9\u4f53\u306b\u4f9d\u5b58\u3059\u308b\u5acc\u6c17\u547c\u5438\u304b\u3089\u3001\u4ee3\u8b1d\u4e2d\u9593\u4f53\u3092\u7528\u3044\u3066\u8fc5\u901f\u306b\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u7523\u751f\u3059\u308b\u767a\u9175\u3078\u3068\u30b7\u30d5\u30c8\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u98df\u990c\u4e2d\u306e\u7cd6\u3092\u5927\u8178\u3078\u4f9b\u7d66\u3057\u3001P. distasonis \u306e\u4ee3\u8b1d\u7d4c\u8def\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30b3\u30cf\u30af\u9178\u7523\u751f\u3092\u4fc3\u9032\u3059\u308b\u72b6\u614b\u3078\u3068\u518d\u69cb\u6210\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84311\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-84311 size-medium\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/b12c8b7e401505670006e9aa6ee0e2d0-610x317.png\" alt=\"\" width=\"610\" height=\"317\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/b12c8b7e401505670006e9aa6ee0e2d0-610x317.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/b12c8b7e401505670006e9aa6ee0e2d0-940x489.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/b12c8b7e401505670006e9aa6ee0e2d0-768x400.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/b12c8b7e401505670006e9aa6ee0e2d0.png 1386w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f36. \u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306f\u98df\u4e8b\u7531\u6765\u306e\u7cd6\u3092 P. distasonis \u306b\u4f9b\u7d66\u3057\u3001\u4ee3\u8b1d\u7d4c\u8def\u306e\u5909\u5316\u3092\u8a98\u5c0e\u3059\u308b<\/strong><br \/>\uff08A\uff09\u901a\u5e38\u98fc\u6599\u304a\u3088\u3073\u30b0\u30eb\u30b3\u30fc\u30b9\u98fc\u6599\u306b\u304a\u3051\u308b\u7cd6\u306e\u5206\u89e3\u30fb\u5438\u53ce\u306e\u6a21\u5f0f\u56f3\u3002<br \/>\uff08B\uff09\u30b0\u30eb\u30b3\u30fc\u30b9\u98fc\u6599\u4e0b\u3067\u306e\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u8a98\u5c0e\u5f8c\u306e\u4f53\u6e29\u5909\u5316\u3002<br \/>\uff08C\uff09\u30b0\u30eb\u30b3\u30fc\u30b9\u98fc\u6599\u4e0b\u3067\u306e\u8131\u9846\u7c92\u80a5\u6e80\u7d30\u80de\u306e\u5272\u5408\u3002<br \/>\uff08D\uff09\u901a\u5e38\u98fc\u6599\u304a\u3088\u3073\u30b0\u30eb\u30b3\u30fc\u30b9\u98fc\u6599\u6442\u990c\u6642\u306b\u304a\u3051\u308b Parabacteroides \u5c5e\u7d30\u83cc\u306e\u76f8\u5bfe\u5b58\u5728\u91cf\u3002<br \/>\uff08E\uff09P. distasonis \u306e\u5897\u6b96\u66f2\u7dda\u3002<br \/>\uff08F\uff09\u30e9\u30de\u30f3\u5206\u5149\u6cd5\u306b\u3088\u308b\u7d30\u83cc\u5185\u4ee3\u8b1d\u72b6\u614b\u306e\u89e3\u6790\uff08\u9178\u5316\u578b\u30fb\u9084\u5143\u578bb\u578b\u30b7\u30c8\u30af\u30ed\u30fc\u30e0\u91cf\uff09\u3002<\/p><\/div>\n<p>\u6700\u5f8c\u306b\u3001\u30de\u30a6\u30b9\u3067\u89b3\u5bdf\u3055\u308c\u305f\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u306b\u3088\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u6291\u5236\u4f5c\u7528\u304c\u30d2\u30c8\u3067\u3082\u8a8d\u3081\u3089\u308c\u308b\u304b\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u533b\u7642\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\uff08JMDC\u533b\u7642\u6a5f\u95a2\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\uff09\u306b\u767b\u9332\u3055\u308c\u305f\u7cd6\u5c3f\u75c5\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u983b\u5ea6\u3068\u85ac\u5264\u6295\u4e0e\u6b74\u3068\u306e\u95a2\u9023\u306b\u3064\u3044\u3066\u591a\u5909\u91cf\u30ed\u30b8\u30b9\u30c6\u30a3\u30c3\u30af\u56de\u5e30\u5206\u6790\u3092\u5b9f\u65bd\u3057\u305f\u7d50\u679c\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u3001\u6d88\u5316\u7cfb\u85ac\u5264\uff08\u6574\u8178\u5264\u306a\u3069\uff09\u3001\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\u304c\u6709\u610f\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f37\u5de6\uff09\u3002\u3053\u306e\u3046\u3061\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u306f\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\uff08\u30aa\u30c3\u30ba\u6bd4\uff1c1\uff09\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f37\u5de6\uff09\u3002\u3055\u3089\u306b\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u3092\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u306e\u670d\u7528\u7fa4\uff0818,026\u4eba\uff09\u3068\u975e\u670d\u7528\u7fa4\uff08103,683\u4eba\uff09\u306b\u5206\u3051\u3066\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u65e2\u5f80\u306f\u975e\u670d\u7528\u7fa4\u306763\u4f8b\u3001\u670d\u7528\u7fa4\u30672\u4f8b\u3067\u3057\u305f\uff08\u56f37\u53f3\uff09\u3002<br \/>\n\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u3092\u542b\u3080\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u306f\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066\u3082\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<div id=\"attachment_84312\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-84312\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-610x314.png\" alt=\"\" width=\"610\" height=\"314\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-610x314.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-940x484.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-768x395.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-1536x791.png 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/05\/695e432aa0b80e914efae12cd0be2a70-2048x1055.png 2048w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><p class=\"wp-caption-text\"><strong>\u56f37.<\/strong> <strong>\u03b1-<\/strong><strong>\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u306e\u670d\u7528\u306f\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u983b\u5ea6\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3059\u308b<\/strong><br \/>JMDC\u533b\u7642\u6a5f\u95a2\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u767b\u9332\u3055\u308c\u305f\u7cd6\u5c3f\u75c5\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c0\u30fc\u30bc\u963b\u5bb3\u85ac\u306e\u670d\u7528\u7fa4\u3068\u975e\u670d\u7528\u7fa4\u306b\u304a\u3051\u308b\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u983b\u5ea6\u3092\u6bd4\u8f03\u3057\u305f\u89e3\u6790\u304a\u3088\u3073\u305d\u306e\u6a21\u5f0f\u56f3\u3002<\/p><\/div>\n<h3>\u4eca\u5f8c\u306e\u5c55\u958b<\/h3>\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001\u65e2\u5b58\u306e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3067\u3042\u308b\u30a2\u30ab\u30eb\u30dc\u30fc\u30b9\u304c\u3001\u8178\u5185\u7d30\u83cc\u306e\u4ee3\u8b1d\u3092\u518d\u30d7\u30ed\u30b0\u30e9\u30e0\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u6291\u5236\u3059\u308b\u65b0\u305f\u306a\u4f5c\u7528\u6a5f\u5e8f\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u306f\u3001\u3053\u306e\u77e5\u898b\u3092\u57fa\u76e4\u3068\u3057\u3066\u3001\u8178\u5185\u7d30\u83cc\u4ee3\u8b1d\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u305f\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u30fb\u6cbb\u7642\u6226\u7565\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u307e\u3059\u3002<br \/>\n\u307e\u305f\u3001\u533b\u7642\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u304a\u3044\u3066\u3082\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u767a\u75c7\u3068\u306e\u95a2\u9023\u304c\u793a\u3055\u308c\u305f\u3053\u3068\u304b\u3089\u3001\u81e8\u5e8a\u7814\u7a76\u3092\u901a\u3058\u3066\u56e0\u679c\u95a2\u4fc2\u306e\u691c\u8a3c\u3092\u9032\u3081\u308b\u3068\u3068\u3082\u306b\u3001\u65e2\u5b58\u85ac\u306e\u65b0\u305f\u306a\u9069\u5fdc\u62e1\u5927\u3084\u30ea\u30dd\u30b8\u30b7\u30e7\u30cb\u30f3\u30b0\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3082\u691c\u8a0e\u3057\u3066\u3044\u304d\u307e\u3059\u3002<br \/>\n\u3055\u3089\u306b\u3001\u8178\u5185\u7d30\u83cc\u306e\u4ee3\u8b1d\u30b7\u30d5\u30c8\u3068\u3044\u3046\u6982\u5ff5\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u9650\u3089\u305a\u3001\u4ee3\u8b1d\u75be\u60a3\u3084\u611f\u67d3\u75c7\u306a\u3069\u5e45\u5e83\u3044\u75be\u60a3\u306b\u5fdc\u7528\u53ef\u80fd\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3001\u672c\u7814\u7a76\u306f\u300c\u8178\u5185\u7d30\u83cc\u4ee3\u8b1d\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3059\u308b\u300d\u3068\u3044\u3046\u65b0\u305f\u306a\u533b\u7642\u30b3\u30f3\u30bb\u30d7\u30c8\u306e\u57fa\u76e4\u3068\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3>\u8ad6\u6587\u60c5\u5831<\/h3>\n<p>\u63b2\u8f09\u8a8c\uff1a<em>Nature Microbiology<\/em> (Springer Nature)\u3000 [Impact Factor (2024): 19.4]<br \/>\n\u8ad6\u6587\u540d\uff1aAcarbose redirects gut microbiome utilization of dietary carbohydrates to suppress anaphylaxis in mice<br \/>\n\u8457\u3000\u8005\uff1aKyosuke Yakabe, Yukinobu Inoue, Yuki Yanagisawa, Shungo Imai, Shunnosuke Suwa, Masahiro Ando, Yuqing Wu, Rina Kurokawa, Srirat Tanakorn, Takeshi Haneda, Tsuyoshi Miki, Masahiro Ito, Akiyoshi Hirayama, Yosuke Kurashima, Shinji Fukuda, Koji Hase, Wataru Suda, Haruko Takeyama, Satoko Hori, and Yun-Gi Kim*\uff08*\u8cac\u4efb\u8457\u8005\uff09<br \/>\n\uff24\uff2f\uff29\uff1a<a href=\"https:\/\/doi.org\/10.1038\/s41564-026-02350-2\">10.1038\/s41564-026-02350-2<\/a><\/p>\n<p>\u672c\u7814\u7a76\u306f\u3001JSPS\u79d1\u7814\u8cbb\uff08JP23K27409, JP23K18223, 22H03541\uff09\u3001AMED\uff0819gm6010004h0004, \u00a0JP223fa627003, JP23gm1010009\uff09\u3001JST CREST\uff08JPMJCR22N1\uff09\u3001FOREST Program\uff08JPMJFR2354\uff09\u3001 JST 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