{"id":83287,"date":"2026-01-16T14:00:09","date_gmt":"2026-01-16T05:00:09","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=83287"},"modified":"2026-01-19T11:56:16","modified_gmt":"2026-01-19T02:56:16","slug":"ai-%e3%81%a7-rna-%e3%82%a2%e3%83%97%e3%82%bf%e3%83%9e%e3%83%bc%e5%89%b5%e8%96%ac%e3%82%92%e5%8a%b9%e7%8e%87%e5%8c%96%e3%81%99%e3%82%8b%e6%8a%80%e8%a1%93%e3%80%8craptscore%e3%80%8d%e3%82%92%e9%96%8b","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/83287","title":{"rendered":"AI\u3067RNA\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u3092\u52b9\u7387\u5316\u3059\u308b\u6280\u8853\u3092\u958b\u767a"},"content":{"rendered":"<h2 style=\"text-align: center;\"><strong>AI\u3067RNA\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u3092\u52b9\u7387\u5316\u3059\u308b\u6280\u8853\u300cRaptScore\u300d\u3092\u958b\u767a<br 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\/>\n<\/strong><\/h2>\n<h3>\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/h3>\n<ul>\n<li>\u00a0RNA\u30a2\u30d7\u30bf\u30de\u30fc<sup>\u203b1<\/sup>\u306e\u7d50\u5408\u6d3b\u6027\uff08\u4f5c\u7528\u30bf\u30fc\u30b2\u30c3\u30c8\u3078\u306e\u304f\u3063\u3064\u304d\u3084\u3059\u3055\uff09\u3092\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30fc\u4e0a\u3067\u5927\u898f\u6a21\u8a00\u8a9e\u30e2\u30c7\u30eb\uff08LLM\uff09<sup>\u203b2<\/sup>\u306b\u3088\u308a\u9ad8\u7cbe\u5ea6\u306b\u8a55\u4fa1\u3059\u308b\u6280\u8853\u300cRaptScore\uff08\u30e9\u30d7\u30c8\u30b9\u30b3\u30a2\uff09\u300d\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/li>\n<li>\u5b9f\u9a13\u30c7\u30fc\u30bf\u306b\u542b\u307e\u308c\u306a\u3044\u672a\u77e5\u306e\u914d\u5217\u3084\u3001\u9577\u3055\u306e\u7570\u306a\u308b\u914d\u5217\u306e\u8a55\u4fa1\u304c\u56f0\u96e3\u3067\u3042\u3063\u305f\u5f93\u6765\u624b\u6cd5\u306e\u8ab2\u984c\u3092LLM\u306e\u6d3b\u7528\u306b\u3088\u308a\u514b\u670d\u3057\u3001\u914d\u5217\u3092\u77ed\u304f\u3057\u305fRNA\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u63a2\u7d22\u30fb\u8a2d\u8a08\u3082\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/li>\n<li>\u672c\u624b\u6cd5\u306b\u3088\u308a\u3001RNA\u30a2\u30d7\u30bf\u30de\u30fc\u533b\u85ac\u54c1\u306e\u958b\u767a\u30b3\u30b9\u30c8\u524a\u6e1b\u3084\u671f\u9593\u77ed\u7e2e\u3001\u54c1\u8cea\u5411\u4e0a\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u6b21\u4e16\u4ee3\u306e\u533b\u85ac\u54c1\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u308bRNA\u30a2\u30d7\u30bf\u30de\u30fc\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306a\u3069\u306e\u6a19\u7684\u306b\u7d50\u5408\u3059\u308b\u80fd\u529b\u3092\u6301\u3061\u307e\u3059\u304c\u3001\u81a8\u5927\u306a\u5019\u88dc\u306e\u4e2d\u304b\u3089\u6709\u671b\u306a\u30a2\u30d7\u30bf\u30de\u30fc\u3092\u63a2\u3057\u51fa\u3057\u3001\u3055\u3089\u306b\u533b\u85ac\u54c1\u3068\u3057\u3066\u88fd\u9020\u30b3\u30b9\u30c8\u3082\u8003\u616e\u3057\u305f\u6700\u9069\u306aRNA\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u9577\u3055\u306b\u77ed\u304f\u52a0\u5de5\u3059\u308b\u4f5c\u696d\u306f\u3001\u591a\u5927\u306a\u52b4\u529b\u3068\u30b3\u30b9\u30c8\u3092\u8981\u3059\u308b\u5b9f\u9a13\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3057\u305f\u3002<br 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href=\"https:\/\/w-rdb.waseda.jp\/html\/100001261_ja.html\">\u6d5c\u7530\u9053\u662d(\u306f\u307e\u3060\u3000\u307f\u3061\u3042\u304d)\u6559\u6388<\/a>\u304a\u3088\u3073\u682a\u5f0f\u4f1a\u793e\u30ea\u30dc\u30df\u30c3\u30af\uff08\u6240\u5728\uff1a\u6771\u4eac\u90fd\u6e2f\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\uff1a\u4e2d\u6751\u7fa9\u4e00\uff09\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6587\u7ae0\u751f\u6210\u306a\u3069\u306b\u4f7f\u308f\u308c\u308b\u5927\u898f\u6a21\u8a00\u8a9e\u30e2\u30c7\u30eb\uff08LLM\uff09\u306e\u6280\u8853\u3092\u5fdc\u7528\u3057\u3001\u5c11\u6570\u306e\u5b9f\u9a13\u30c7\u30fc\u30bf\u304b\u3089\u4efb\u610f\u306eRNA\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u7d50\u5408\u6d3b\u6027\u3092\u8a55\u4fa1\u3067\u304d\u308b\u6280\u8853RaptScore\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<br \/>\n\u3053\u308c\u306b\u3088\u308a\u3001\u5f93\u6765\u6cd5\u3067\u306f\u56f0\u96e3\u3060\u3063\u305f\u914d\u5217\u306e\u77ed\u7e2e\u5316\u3084\u672a\u77e5\u306e\u5019\u88dc\u914d\u5217\u306e\u8a55\u4fa1\u304c\u5bb9\u6613\u306b\u306a\u308a\u3001\u5275\u85ac\u7814\u7a76\u306e\u52b9\u7387\u5316\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<br \/>\n\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u56fd\u969b\u5b66\u8853\u8a8c\u300cNucleic Acids Research\u300d\u306b2026\u5e741\u670814\u65e5\u306b\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u8ad6\u6587\u540d\uff1aRaptScore: a large language model-based algorithm for versatile aptamer evaluation<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-83294\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/01\/29d3bc99193cb0b837fb8cc53f050ae5-1-610x254.png\" alt=\"\" width=\"610\" height=\"254\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/01\/29d3bc99193cb0b837fb8cc53f050ae5-1-610x254.png 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/01\/29d3bc99193cb0b837fb8cc53f050ae5-1-940x392.png 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/01\/29d3bc99193cb0b837fb8cc53f050ae5-1-768x320.png 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2026\/01\/29d3bc99193cb0b837fb8cc53f050ae5-1.png 1488w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" 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\/>\n\u672c\u7814\u7a76\u306e\u4e3b\u306a\u6210\u679c\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n<ul>\n<li><strong>\u9ad8\u7cbe\u5ea6\u306a\u6d3b\u6027\u4e88\u6e2c\u3092\u5b9f\u73fe<\/strong><br \/>\n\u5b9f\u9a13\u306b\u3088\u308b\u7d50\u5408\u6d3b\u6027\u6e2c\u5b9a\uff08SPR\u6cd5\uff09\u306e\u7d50\u679c\u3068\u3001AI\u304c\u7b97\u51fa\u3057\u305fRaptScore\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u9ad8\u3044\u76f8\u95a2\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5c11\u6570\u306e\u5b9f\u9a13\u30c7\u30fc\u30bf\u3092\u5143\u306b\u4efb\u610f\u306e\u914d\u5217\u306e\u7d50\u5408\u529b\u3092\u63a8\u5b9a\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/li>\n<li><strong>\u300c\u77ed\u9396\u5316\u300d\u3078\u306e\u5fdc\u7528\u5b9f\u8a3c<\/strong><br \/>\n\u5b9f\u9a13\u7684\u306a\u691c\u8a3c\u3092\u4ecb\u3055\u305a\u3068\u3082\u3001RaptScore\u304c\u9ad8\u3044\u5024\u3092\u793a\u3059\u3088\u3046\u306b\u914d\u5217\u3092\u524a\u308b\u3053\u3068\u3067\u3001\u7d50\u5408\u6d3b\u6027\u3092\u7dad\u6301\u3001\u3042\u308b\u3044\u306f\u5411\u4e0a\u3055\u305b\u306a\u304c\u3089\u3001\u914d\u5217\u9577\u3092\u77ed\u304f\u3067\u304d\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3057\u307e\u3057\u305f\u3002\u5143\u306e\u914d\u5217\u304b\u3089\u9577\u3055\u3092\u6700\u59273\u5272\u307b\u3069\u524a\u308a\u3064\u3064\u3082\u7d50\u5408\u529b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002<\/li>\n<li><strong>\u751f\u6210AI\u3068\u306e\u9023\u643a\u306b\u3088\u308b\u52b9\u7387\u5316<\/strong><br \/>\n\u540c\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u958b\u767a\u3057\u305fRNA\u30a2\u30d7\u30bf\u30de\u30fc\u751f\u6210AI\u300cRaptGen\u300d\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001AI\u304c\u751f\u6210\u3057\u305f\u5019\u88dc\u914d\u5217\u306e\u4e2d\u304b\u3089\u3001\u5b9f\u969b\u306b\u5b9f\u9a13\u3059\u3079\u304d\u6709\u671b\u306a\u5019\u88dc\u3092\u9ad8\u78ba\u7387\u3067\u9078\u629c\u3067\u304d\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n<h3><strong>\u7814\u7a76\u306e\u6ce2\u53ca\u52b9\u679c\u3084\u793e\u4f1a\u7684\u5f71\u97ff<\/strong><\/h3>\n<p>\u672c\u6210\u679c\u306f\u3001RNA\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u306b\u8907\u6570\u306e\u5074\u9762\u304b\u3089\u5bc4\u4e0e\u3057\u3046\u308bAI\u6280\u8853\u3067\u3059\u3002 \u7b2c\u4e00\u306b\u3001\u88fd\u9020\u30b3\u30b9\u30c8\u306e\u524a\u6e1b\u3067\u3059\u3002\u5316\u5b66\u5408\u6210\u3067\u88fd\u9020\u3055\u308c\u308b\u6838\u9178\u533b\u85ac\u54c1\u306f\u3001\u914d\u5217\u304c\u77ed\u304f\u306a\u308b\u307b\u3069\u88fd\u9020\u30b3\u30b9\u30c8\u304c\u4e0b\u304c\u308a\u3001\u54c1\u8cea\u7ba1\u7406\u3082\u5bb9\u6613\u306b\u306a\u308a\u307e\u3059\u3002RaptScore\u3092\u7528\u3044\u308c\u3070\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30fc\u4e0a\u3067\u52b9\u7387\u7684\u306a\u77ed\u9396\u5316\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002 \u7b2c\u4e8c\u306b\u3001\u958b\u767a\u30b9\u30d4\u30fc\u30c9\u306e\u5411\u4e0a\u3067\u3059\u3002\u5b9f\u9a13\u3092\u3059\u308b\u524d\u306bAI\u3067\u6709\u671b\u306a\u5019\u88dc\u3092\u7d5e\u308a\u8fbc\u3081\u308b\u305f\u3081\u3001\u5b9f\u9a13\u56de\u6570\u3092\u6e1b\u3089\u3057\u3001\u52b9\u7387\u7684\u306b\u5f37\u529b\u306a\u30a2\u30d7\u30bf\u30de\u30fc\u3092\u767a\u898b\u3067\u304d\u307e\u3059\u3002 \u3053\u308c\u3089\u306b\u3088\u308a\u3001\u304c\u3093\u3084\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306a\u3069\u306b\u5bfe\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u85ac\u3084\u8a3a\u65ad\u85ac\u304c\u3001\u3088\u308a\u65e9\u304f\u3001\u3088\u308a\u5b89\u4fa1\u306b\u793e\u4f1a\u306b\u5c4a\u304f\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3><strong>\u8ab2\u984c\u3001\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h3>\n<p>\u73fe\u5728\u306eRaptScore\u306e\u8ab2\u984c\u306e\u4e00\u3064\u306f\u5869\u57fa\u914d\u5217\u306e\u4e26\u3073\u306e\u307f\u3092\u5b66\u7fd2\u3057\u3066\u304a\u308a\u3001RNA\u304c\u5f62\u4f5c\u308b3\u6b21\u5143\u306e\u7acb\u4f53\u69cb\u9020\u306e\u60c5\u5831\u306f\u76f4\u63a5\u7684\u306b\u306f\u8003\u616e\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u3067\u3059\u3002\u4eca\u5f8c\u306f\u3001\u7acb\u4f53\u69cb\u9020\u306e\u60c5\u5831\u3082\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u4e88\u6e2c\u7cbe\u5ea6\u3092\u3055\u3089\u306b\u9ad8\u3081\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u307e\u3059\u3002<\/p>\n<h3><strong>\u7814\u7a76\u8005\u306e\u30b3\u30e1\u30f3\u30c8<\/strong><\/h3>\n<p>\u672c\u7814\u7a76\u306f\u3001\u719f\u7df4\u7814\u7a76\u8005\u304c\u57f9\u3063\u3066\u304d\u305f\u30a2\u30d7\u30bf\u30de\u30fc\u306b\u95a2\u3059\u308b\u7d4c\u9a13\u3084\u6d1e\u5bdf\u3092\u88dc\u5b8c\u3057\u3001\u30a2\u30d7\u30bf\u30de\u30fc\u306e\u76ee\u5229\u304d\u3084\u30c7\u30b6\u30a4\u30f3\u3092\u30c7\u30fc\u30bf\u3068AI\u306b\u3088\u308a\u52b9\u7387\u5316\u30fb\u9ad8\u5ea6\u5316\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3059\u3082\u306e\u3067\u3059\u3002\u3053\u308c\u307e\u3067\u958b\u767a\u3057\u3066\u304d\u305f\u751f\u6210AI\u30fbRaptGen\u306a\u3069\u3068\u3042\u308f\u305b\u3066\u3001\u6b21\u4e16\u4ee3\u306e\u65b0\u85ac\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u308b\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u3092\u3055\u3089\u306b\u52a0\u901f\u3055\u305b\u308b\u6280\u8853\u3068\u306a\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3><strong>\u7528\u8a9e\u89e3\u8aac<\/strong><\/h3>\n<p>\u203b1 RNA\u30a2\u30d7\u30bf\u30de\u30fc<br \/>\n\u30bf\u30fc\u30b2\u30c3\u30c8\u5206\u5b50\uff08\u30bf\u30f3\u30d1\u30af\u8cea\u306a\u3069\uff09\u306b\u5f37\u304f\u7d50\u5408\u3059\u308b\u80fd\u529b\u3092\u6301\u3064\u3001\u77ed\u3044RNA\u5206\u5b50\u3002\u6297\u4f53\u533b\u85ac\u54c1\u306b\u4ee3\u308f\u308b\u6b21\u4e16\u4ee3\u306e\u4e2d\u5206\u5b50\u533b\u85ac\u54c1\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u203b2 \u5927\u898f\u6a21\u8a00\u8a9e\u30e2\u30c7\u30eb\uff08LLM\uff09<br \/>\n\u5927\u91cf\u306e\u30c6\u30ad\u30b9\u30c8\u30c7\u30fc\u30bf\u3092\u5b66\u7fd2\u3057\u3001\u6587\u7ae0\u306e\u751f\u6210\u3084\u8a55\u4fa1\u3092\u884c\u3046AI\u30e2\u30c7\u30eb\u3002\u672c\u7814\u7a76\u3067\u306f\u3001DNA\/RNA\u306e\u5869\u57fa\u914d\u5217\uff08A, G, C, T\/U\uff09\u3092\u8a00\u8a9e\u3068\u898b\u7acb\u3066\u3066\u5b66\u7fd2\u3055\u305b\u305f\u30e2\u30c7\u30eb\uff08DNABERT\uff09\u3092\u5fdc\u7528\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u203b3 SELEX\uff08\u30bb\u30ec\u30c3\u30af\u30b9\uff09\u6cd5<br \/>\nSystematic Evolution of Ligands by Exponential enrichment\u306e\u7565\u3002\u81a8\u5927\u306a\u7a2e\u985e\u306eRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u304b\u3089\u3001\u6a19\u7684\u7269\u8cea\u306b\u7d50\u5408\u3059\u308b\u3082\u306e\u3060\u3051\u3092\u9078\u3073\u51fa\u3057\u3001\u5897\u5e45\u3055\u305b\u308b\u5de5\u7a0b\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u3067\u3001\u7d50\u5408\u529b\u306e\u5f37\u3044\u30a2\u30d7\u30bf\u30de\u30fc\u3092\u53d6\u5f97\u3059\u308b\u5b9f\u9a13\u624b\u6cd5\u3002<\/p>\n<p>\u203b4 \u77ed\u9396\u5316<br \/>\n\u30a2\u30d7\u30bf\u30de\u30fc\u533b\u85ac\u54c1\u306e\u5b9f\u7528\u5316\u306b\u304a\u3044\u3066\u3001\u6d3b\u6027\u306b\u4e0d\u8981\u306a\u90e8\u5206\u3092\u524a\u304e\u843d\u3068\u3057\u3001\u914d\u5217\u3092\u77ed\u304f\u3059\u308b\u5de5\u7a0b\u3002\u88fd\u9020\u30b3\u30b9\u30c8\u524a\u6e1b\u3084\u526f\u4f5c\u7528\u4f4e\u6e1b\u306e\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u304c\u3001\u591a\u304f\u306e\u5b9f\u9a13\u7684\u306a\u8a66\u884c\u932f\u8aa4\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<h3>\u30ad\u30fc\u30ef\u30fc\u30c9<\/h3>\n<p>RNA\u30a2\u30d7\u30bf\u30de\u30fc\u3001\u5275\u85ac\u3001\u5927\u898f\u6a21\u8a00\u8a9e\u30e2\u30c7\u30eb\u3001LLM\u3001AI\u3001RaptScore<\/p>\n<h3><strong>\u8ad6\u6587\u60c5\u5831<\/strong><\/h3>\n<p>\u96d1\u8a8c\u540d\uff1aNucleic Acids Research<br \/>\n\u8ad6\u6587\u540d\uff1aRaptScore: a large language model-based algorithm for versatile aptamer evaluation\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6728\u6751(\u5c71\ufa11)\u6643 (\u65e9\u7a32\u7530\u5927\u5b66), \u5b89\u9054\u5065\u6717, \u4e2d\u6751\u91cd\u5b5d, \u4e2d\u6751\u7fa9\u4e00 (\u682a\u5f0f\u4f1a\u793e\u30ea\u30dc\u30df\u30c3\u30af), \u6d5c\u7530\u9053\u662d*\uff08<span data-olk-copy-source=\"MessageBody\">\u65e9\u7a32\u7530\u5927\u5b66\u3001\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6240<\/span>\uff09<br \/>\n*\uff1a\u8cac\u4efb\u8457\u8005<br \/>\n\u63b2\u8f09\u65e5\u6642\uff1a2026\u5e741\u670814\u65e5<br \/>\n\u63b2\u8f09URL\uff1a<a href=\"https:\/\/academic.oup.com\/nar\/article\/54\/2\/gkaf1480\/8425320?guestAccessKey=7b0bb9bc-05b7-44a1-bc03-b25c04e9280c&amp;utm_source=authortollfreelink&amp;utm_campaign=nar&amp;utm_medium=email\">https:\/\/academic.oup.com\/nar\/article\/54\/2\/gkaf1480\/8425320?guestAccessKey=7b0bb9bc-05b7-44a1-bc03-b25c04e9280c&amp;utm_source=authortollfreelink&amp;utm_campaign=nar&amp;utm_medium=email<\/a><br \/>\nDOI\uff1a<a href=\"https:\/\/doi.org\/10.1093\/nar\/gkaf1480\">https:\/\/doi.org\/10.1093\/nar\/gkaf1480<\/a><\/p>\n<h3><strong>\u7814\u7a76\u52a9\u6210<\/strong><\/h3>\n<p>\u7814\u7a76\u8cbb\u540d\uff1aJST\u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696d CREST\u300c\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u5275\u767a\u306b\u8cc7\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u57fa\u76e4\u6280\u8853\u306e\u5275\u51fa\u3068\u7d71\u5408\u5316\u300d<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a\u4eba\u5de5\u77e5\u80fd\u6280\u8853\u3092\u7528\u3044\u305f\u9769\u65b0\u7684\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6d5c\u7530\u9053\u662d\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1aJST \u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696dCREST\u300c\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u5275\u767a\u306b\u8cc7\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u57fa\u76e4\u6280\u8853\u306e\u5275\u51fa\u3068\u7d71\u5408\u5316\u300d\uff08\u6804\u85e4\u7a14\u7dcf\u62ec\uff09<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1aAI\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u30d7\u30ed\u30b8\u30a7\u30af\u30c8<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6d5c\u7530 \u9053\u662d\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a \u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d \u5b66\u8853\u5909\u9769\u9818\u57df\u7814\u7a76(A)(25H01310)<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a\u751f\u7269\u306e\u514d\u75ab\u53cd\u5fdc\u3092\u624b\u304c\u304b\u308a\u3068\u3057\u305f\u64b9\u4e71RNA\u306e\u7db2\u7f85\u7684\u63a2\u7d22\u3068\u7279\u5fb4\u4ed8\u3051<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u5ddd\u5d0e \u7d14\u83dc\uff08\u5343\u8449\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d \u57fa\u76e4\u7814\u7a76(S)(25H00427)<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a\u65b0\u898f\u7ffb\u8a33\u8a98\u5c0e\u6280\u8853\u3092\u7528\u3044\u305f\u74b0\u72b6RNA\u306e\u5206\u5b50\u8a2d\u8a08\u3068\u5fdc\u7528<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u963f\u90e8 \u6d0b\uff08\u540d\u53e4\u5c4b\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a\u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d \u6311\u6226\u7684\u7814\u7a76(\u958b\u62d3)(24K21326)<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1aRNA\u30ea\u30a4\u30f3\u30ab\u30cd\u30fc\u30b7\u30e7\u30f3<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6d5c\u7530 \u9053\u662d\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/p>\n<p>\u7814\u7a76\u8cbb\u540d\uff1a \u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d \u57fa\u76e4\u7814\u7a76(A)(23H00509)<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1aRNA\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u5206\u5b50\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u57fa\u3065\u304f\u751f\u7269\u5b66\u7684\u76f8\u5206\u96e2\u306e\u4fef\u77b0\u7684\u30fb\u4f53\u7cfb\u7684\u7406\u89e3<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u6d5c\u7530 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