{"id":80651,"date":"2025-04-16T11:00:51","date_gmt":"2025-04-16T02:00:51","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=80651"},"modified":"2025-04-15T15:10:12","modified_gmt":"2025-04-15T06:10:12","slug":"%e9%85%b5%e6%af%8d%e7%99%ba%e9%85%b5%e3%83%8b%e3%83%b3%e3%83%8b%e3%82%af%e3%81%8c%e7%b4%b0%e8%83%9e%e3%81%ae%e5%81%a5%e5%ba%b7%e3%82%92%e5%ae%88%e3%82%8b%e4%bb%95%e7%b5%84%e3%81%bf%e3%82%92%e8%a7%a3","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/80651","title":{"rendered":"\u9175\u6bcd\u767a\u9175\u30cb\u30f3\u30cb\u30af\u304c\u7d30\u80de\u306e\u5065\u5eb7\u3092\u5b88\u308b\u4ed5\u7d44\u307f\u3092\u89e3\u660e"},"content":{"rendered":"<h1 style=\"text-align: center;\"><strong>\u9175\u6bcd\u767a\u9175\u30cb\u30f3\u30cb\u30af\u304c\u7d30\u80de\u306e\u5065\u5eb7\u3092\u5b88\u308b\u4ed5\u7d44\u307f\u3092\u89e3\u660e<\/strong><\/h1>\n<p style=\"text-align: center;\"><big>\u2014 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-80656\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main.jpg\" alt=\"\" width=\"939\" height=\"567\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main.jpg 2516w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main-610x369.jpg 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main-940x568.jpg 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main-768x464.jpg 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main-1536x928.jpg 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_main-2048x1237.jpg 2048w\" sizes=\"auto, (max-width: 939px) 100vw, 939px\" 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\/>\n\u3055\u3089\u306b\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001\u305d\u306e\u52b9\u679c\u306e\u9375\u304c\u300c\u30dd\u30ea\u30a2\u30df\u30f3<sup>\u203b\uff12<\/sup>\u30d0\u30e9\u30f3\u30b9\u300d\u306b\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u6d3b\u6027\u5316\u6210\u5206\u3068\u3057\u3066\u30dd\u30ea\u30a2\u30df\u30f3\u3092\u898b\u51fa\u3057\u3001\u9175\u6bcd\u767a\u9175\u306b\u3093\u306b\u304f\u306b\u542b\u307e\u308c\u308b\u300c\u30b9\u30da\u30eb\u30df\u30f3\u300d\u3068\u300c\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u300d\u3068\u3044\u3046\uff12\u7a2e\u985e\u306e\u30dd\u30ea\u30a2\u30df\u30f3\u306e\u6bd4\u7387\u304c\u6700\u9069\u5316\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3068\u3044\u3046\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u30cb\u30e5\u30fc\u30c8\u30ea\u30b2\u30ce\u30df\u30af\u30b9<sup>\u203b\uff13<\/sup>\u306e\u624b\u6cd5\u3092\u7528\u3044\u3066\u3001\u8ee2\u5199\u56e0\u5b50EGR1<sup>\u203b\uff14<\/sup>\u304c\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u6d3b\u6027\u5316\u306b\u95a2\u4e0e\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u9175\u6bcd\u767a\u9175\u30cb\u30f3\u30cb\u30af\u306f\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u4ecb\u3057\u305f\u7d30\u80de\u5185\u3078\u306e\u7570\u5e38\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u84c4\u7a4d\u306b\u3088\u3063\u3066\u60f9\u8d77\u3055\u308c\u308b\u7d30\u80de\u30b9\u30c8\u30ec\u30b9<sup>\u203b\uff15\u3084<\/sup>\u9178\u5316\u969c\u5bb3\u3078\u306e\u4fdd\u8b77\u52b9\u679c\u3082\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306a\u3069\u306e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u3084\u304c\u3093\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u4e88\u9632\u306a\u3069\u306b\u5f79\u7acb\u3064\u6a5f\u80fd\u6027\u98df\u54c1\u7d20\u6750\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u767a\u898b\u306f\u3001\u5358\u306b\u98df\u54c1\u306e\u6a5f\u80fd\u6027\u6210\u5206\u306e\u300c\u91cf\u300d\u3060\u3051\u3067\u306a\u304f\u300c\u6210\u5206\u30d0\u30e9\u30f3\u30b9\u300d\u304c\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3059\u753b\u671f\u7684\u306a\u7814\u7a76\u6210\u679c\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br \/>\n\u672c\u7814\u7a76\u6210\u679c\u306f\u300eMolecular Nutrition &amp; Food Research\u300f\uff08\u8ad6\u6587\u540d\uff1a<a href=\"https:\/\/doi.org\/10.1002\/mnfr.202400606\" target=\"_blank\" rel=\"noopener\">The Yeast-Fermented Garlic and a Spermine\/Spermidine Activates Autophagy via EGR1 Transcriptional Factor<\/a>\uff09\u306b\u3066\u30012025\u5e742\u670813\u65e5\uff08\u6728\uff09\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<h4>\uff08\uff11\uff09\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u305f\u3053\u3068<\/h4>\n<p>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u7d30\u80de\u5185\u306e\u30ea\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u30b7\u30b9\u30c6\u30e0\u3068\u3057\u3066\u3001\u7d30\u80de\u5185\u6210\u5206\u3092\u5206\u89e3\u3057\u518d\u5229\u7528\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u304a\u308a\u3001\u3053\u306e\u30b7\u30b9\u30c6\u30e0\u304c\u6b63\u5e38\u306b\u6a5f\u80fd\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u304c\u82e5\u3005\u3057\u304f\u5065\u5eb7\u306a\u72b6\u614b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u6d3b\u6027\u306f\u52a0\u9f62\u3068\u3068\u3082\u306b\u4f4e\u4e0b\u3057\u3001\u304c\u3093\u3084\u795e\u7d4c\u5909\u6027\u75be\u60a3\u306a\u3069\u306e\u591a\u304f\u306e\u52a0\u9f62\u6027\u75be\u60a3\u306e\u767a\u75c7\u306b\u95a2\u308f\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3068\u3082\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u6d3b\u6027\u3092\u9ad8\u3081\u305f\u30e2\u30c7\u30eb\u751f\u7269\u3067\u306f\u3001\u904b\u52d5\u6a5f\u80fd\u3084\u9ad8\u6b21\u8133\u6a5f\u80fd\u306a\u3069\u3092\u7dad\u6301\u3057\u305f\u307e\u307e\u5bff\u547d\u3092\u5ef6\u4f38\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u901a\u5e38\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u7a7a\u8179\u6642\u306b\u6d3b\u6027\u5316\u3057\u307e\u3059\u304c\u3001\u6975\u7aef\u306a\u98df\u4e8b\u5236\u9650\u306f\u73fe\u5b9f\u7684\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3053\u3067\u3001\u65e5\u5e38\u7684\u306b\u98df\u3079\u3089\u308c\u308b\u98df\u54c1\u304b\u3089\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u6d3b\u6027\u5316\u6210\u5206\u3092\u898b\u3064\u3051\u308b\u7814\u7a76\u304c\u4e16\u754c\u4e2d\u3067\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u6d3b\u6027\u6e2c\u5b9a\u65b9\u6cd5\u304c\u6b63\u78ba\u3067\u306a\u3044\u7814\u7a76\u304c\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u3002<br 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\/>\n\u4e00\u65b9\u3067\u3001\u4e73\u9178\u767a\u9175\u3067\u306f\u3001\u3080\u3057\u308d\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u30cb\u30f3\u30cb\u30af\u306e\u767a\u9175\u65b9\u6cd5\u306b\u3088\u3063\u3066\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u5909\u5316\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u5236\u5fa1\u3059\u308b\u98df\u54c1\u306e\u958b\u767a\u306b\u304a\u3044\u3066\u3001\u98df\u54c1\u52a0\u5de5\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u793a\u3059\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\uff08\u56f31\uff09\u3002<\/p>\n<div id=\"attachment_80652\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-80652\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_1.jpg\" alt=\"\" width=\"642\" height=\"433\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_1.jpg 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_1-610x411.jpg 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_1-940x634.jpg 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_1-768x518.jpg 768w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" \/><p 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id=\"attachment_80653\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-80653\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-scaled.jpg\" alt=\"\" width=\"759\" height=\"336\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-scaled.jpg 2560w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-610x270.jpg 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-940x416.jpg 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-768x340.jpg 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-1536x680.jpg 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_2-2048x906.jpg 2048w\" sizes=\"auto, (max-width: 759px) 100vw, 759px\" \/><p 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id=\"attachment_80654\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-80654\" src=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-scaled.jpg\" alt=\"\" width=\"789\" height=\"354\" srcset=\"https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-scaled.jpg 2560w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-610x274.jpg 610w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-940x422.jpg 940w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-768x345.jpg 768w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-1536x689.jpg 1536w, https:\/\/www.waseda.jp\/inst\/research\/assets\/uploads\/2025\/04\/2504yano_3-2048x919.jpg 2048w\" sizes=\"auto, (max-width: 789px) 100vw, 789px\" \/><p 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\/>\n\u539f\u6838\u751f\u7269\u304b\u3089\u9ad8\u7b49\u52d5\u690d\u7269\u306b\u81f3\u308b\u307e\u3067\u307b\u307c\u3059\u3079\u3066\u306e\u751f\u7269\u306e\u7d30\u80de\u5185\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3001\u30a2\u30df\u30ce\u57fa\u304c2\u3064\u4ee5\u4e0a\u7d50\u5408\u3057\u305f\u70ad\u5316\u6c34\u7d20\u5316\u5408\u7269\u3002\u7d30\u80de\u306e\u6210\u9577\u3084\u5897\u6b96\u306a\u3069\u3001\u7d30\u80de\u306e\u751f\u547d\u6d3b\u52d5\u306b\u95a2\u308f\u308b\u91cd\u8981\u306a\u7269\u8cea\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u4ee3\u8868\u7684\u306a\u3082\u306e\u3068\u3057\u3066\u30d7\u30c8\u30ec\u30c3\u30b7\u30f3\u3001\u30b9\u30da\u30eb\u30df\u30b8\u30f3\u3001\u30b9\u30da\u30eb\u30df\u30f3\u304c\u6319\u3052\u3089\u308c\u308b\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u3001\u30dd\u30ea\u30a2\u30df\u30f3\u306f\u52a0\u9f62\u3068\u3068\u3082\u306b\u4f53\u5185\u91cf\u304c\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304a\u308a\u3001\u305d\u306e\u5065\u5eb7\u7dad\u6301\u6a5f\u80fd\u304c\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u306e\u5206\u91ce\u3067\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<p><strong>\u203b\uff13 \u30cb\u30e5\u30fc\u30c8\u30ea\u30b2\u30ce\u30df\u30af\u30b9\uff08Nutritional Genomics\uff09<\/strong><br \/>\n\u98df\u54c1\u6210\u5206\u306a\u3069\u306b\u3088\u308b\u751f\u4f53\u5185\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u3078\u306e\u5f71\u97ff\u3092\u89e3\u6790\u3059\u308b\u624b\u6cd5\u3002mRNA\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u4ee3\u8b1d\u7269\u306a\u3069\u306e\u91cf\u7684\u5909\u52d5\u3092\u30c8\u30e9\u30f3\u30b9\u30af\u30ea\u30d7\u30c8\u30fc\u30e0\u89e3\u6790\u3001\u30d7\u30ed\u30c6\u30aa\u30fc\u30e0\u89e3\u6790\u3001\u30e1\u30bf\u30dc\u30ed\u30fc\u30e0\u89e3\u6790\u306a\u3069\u306e\u6280\u8853\u306b\u3088\u3063\u3066\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3059\u308b\u3002\u3053\u308c\u307e\u3067\u306b\u30cb\u30e5\u30fc\u30c8\u30ea\u30b2\u30ce\u30df\u30af\u30b9\u306f\u3001\u98df\u54c1\u306e\u6a5f\u80fd\u6027\u8a55\u4fa1\u3084\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u63a2\u7d22\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u5206\u91ce\u3067\u5fdc\u7528\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b5\u30fc\u3092\u7528\u3044\u305fRNA-seq\u3092\u6d3b\u7528\u3057\u3001\u7d30\u80de\u5185\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316\u3092\u7db2\u7f85\u7684\u306b\u691c\u8a3c\u3059\u308b\u3053\u3068\u3067\u3001\u305d\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u3092\u5305\u62ec\u7684\u306b\u89e3\u6790\u3057\u305f\u3002<\/p>\n<p><strong>\u203b\uff14 \u8ee2\u5199\u56e0\u5b50EGR1\uff08Early growth response protein1\uff09<\/strong><br \/>\n\u7d30\u80de\u3078\u306e\u523a\u6fc0\u306b\u5fdc\u7b54\u3057\u3066\u8fc5\u901f\u304b\u3064\u4e00\u6642\u7684\u306b\u767a\u73fe\u304c\u8a98\u5c0e\u3055\u308c\u308b\u6700\u521d\u671f\u907a\u4f1d\u5b50\u3002EGR1\u306f\u8ee2\u5199\u8abf\u7bc0\u56e0\u5b50\u3068\u3057\u3066\u3001\u6a19\u7684\u907a\u4f1d\u5b50\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u9818\u57df\u306b\u7d50\u5408\u3057\u3001\u305d\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u8abf\u6574\u3059\u308b\u3002<\/p>\n<p><strong>\u203b\uff15 \u7570\u5e38\u30bf\u30f3\u30d1\u30af\u8cea\u30b9\u30c8\u30ec\u30b9<\/strong><br \/>\n\u7d30\u80de\u30c0\u30e1\u30fc\u30b8\u306b\u3064\u306a\u304c\u308b\u3001\u7570\u5e38\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u3088\u308b\u51dd\u96c6\u3084\u7d30\u80de\u5185\u306e\u84c4\u7a4d\u306e\u3053\u3068\u3002\u52a0\u9f62\u306b\u3068\u3082\u306a\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u4ee3\u8b1d\u56de\u8ee2\u306e\u4f4e\u4e0b\u3084\u3001\u6d3b\u6027\u9178\u7d20\u306b\u3088\u308b\u5316\u5b66\u4fee\u98fe\u306a\u3069\u306b\u3088\u3063\u3066\u3001\u672c\u6765\u306e\u6a5f\u80fd\u3092\u5931\u3063\u305f\u3001\u307e\u305f\u306f\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u308b\u3002\u4e00\u65b9\u3067\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306a\u3069\u306e\u7d30\u80de\u5185\u306e\u54c1\u8cea\u7ba1\u7406\u6a5f\u69cb\u306f\u3001\u3053\u308c\u3089\u7570\u5e38\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5206\u89e3\u30fb\u9664\u53bb\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u3002<\/p>\n<p><strong>\u203b\uff16 mTORC1\uff08mammalian target of rapamycin complex 1\uff09<\/strong><br \/>\n\u7d30\u80de\u5185\u306e\u30ea\u30f3\u9178\u5316\u9175\u7d20\u8907\u5408\u4f53\u3067\u3042\u308a\u3001\u6804\u990a\u7d20\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u3001\u9178\u5316\u9084\u5143\u72b6\u614b\u306e\u30bb\u30f3\u30b5\u30fc\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306a\u3069\u306e\u751f\u5408\u6210\u306e\u6d3b\u6027\u5316\u3092\u62c5\u3046\u3002\u30a2\u30df\u30ce\u9178\u306a\u306e\u3069\u306e\u6804\u990a\u98e2\u9913\u72b6\u614b\u3067\u306fmTORC1\u306f\u4e0d\u6d3b\u6027\u5316\u3055\u308c\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u8a98\u5c0e\u3055\u308c\u308b\u3002<\/p>\n<h4>\uff08\uff17\uff09\u8ad6\u6587\u60c5\u5831<\/h4>\n<p>\u96d1\u8a8c\u540d\uff1a<a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/16134133\" target=\"_blank\" rel=\"noopener\">Molecular Nutrition &amp; Food Research<\/a><br \/>\n\u8ad6\u6587\u540d\uff1a<a href=\"https:\/\/doi.org\/10.1002\/mnfr.202400606\" target=\"_blank\" rel=\"noopener\">The Yeast-Fermented Garlic and a Spermine\/Spermidine Activates Autophagy via EGR1 Transcriptional Factor<\/a><br \/>\n\u57f7\u7b46\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a\u8b1d \u5803<sup>1\u30014\u3001\uff0a<\/sup>\u3001\u77e2\u91ce \u654f\u53f2<sup>1\u3001\uff0a<\/sup>\u3001\u30ef\u30f3 \u30b8\u30f3\u30e6\u30f3<sup>1<\/sup>\u3001\u5c71\u8d8a \u6b63\u6c70<sup>1\u3001<\/sup>\u592a\u7530 \u667a\u7d75<sup>2<\/sup>\u3001\u5b87\u90fd \u62d3\u6d0b<sup>2<\/sup>\u3001\u5742\u4e95 \u9ebb\u8863\u5b50<sup>3<\/sup>\u3001Xi He<sup>4<\/sup>\u3001\u5409\u5d0e \u5609\u4e00<sup>5<\/sup>\u3001\u4e45\u4fdd\u7530 \u62d3\u6d77<sup>6<\/sup>\u3001\u5927\u897f \u5eb7\u592a<sup>3<\/sup>\u3001\u539f \u592a\u4e00<sup>1\u3001\u203b\u3000<\/sup>\uff0a\u7b46\u982d\u8457\u8005\u3000\u203b\u8cac\u4efb\u8457\u8005<br \/>\n1: \u65e9\u7a32\u7530\u5927\u5b66 \u4eba\u9593\u79d1\u5b66\u5b66\u8853\u9662<br \/>\n2: \u9577\u5d0e\u56fd\u969b\u5927\u5b66 \u85ac\u5b66\u90e8<br \/>\n3: \u5fb3\u5cf6\u5927\u5b66 \u533b\u5b66\u90e8<br \/>\n4: \u6e56\u5357\u8fb2\u696d\u5927\u5b66 \u52d5\u7269\u79d1\u5b66\u6280\u8853\u5b66\u90e8<br \/>\n5: \u611b\u77e5\u770c\u533b\u7642\u7642\u80b2\u7dcf\u5408\u30bb\u30f3\u30bf\u30fc \u767a\u9054\u969c\u5bb3\u7814\u7a76\u6240<br \/>\n6: \u5929\u771f\u5802\u682a\u5f0f\u4f1a\u793e<br \/>\n\u63b2\u8f09\u65e5\u6642\uff1a2025\u5e742\u670813\u65e5\uff08\u6728\uff09<br \/>\n\u63b2\u8f09URL\uff1a<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.202400606\" target=\"_blank\" rel=\"noopener\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.202400606<\/a><br \/>\nDOI\uff1a<a href=\"https:\/\/doi.org\/10.1002\/mnfr.202400606\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1002\/mnfr.202400606<\/a><\/p>\n<h4>\uff08\uff18\uff09\u7814\u7a76\u52a9\u6210<\/h4>\n<ul>\n<li>\u7814\u7a76\u8cbb\u540d\uff1a\u6587\u79d1\u7701 \u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a \u5929\u7136\u533b\u85ac\u8cc7\u6e90\u3092\u57fa\u76e4\u3068\u3057\u305f\u5e0c\u5c11\u96e3\u75c5\u306e\u9769\u65b0\u7684\u6cbb\u7642\u6cd5\u306e\u958b\u767a<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a \u539f \u592a\u4e00\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/li>\n<li>\u7814\u7a76\u8cbb\u540d\uff1a\u6b66\u7530\u79d1\u5b66\u632f\u8208\u8ca1\u56e3<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a \u30aa\u30eb\u30ac\u30cd\u30e9\u8ca0\u8377\u8efd\u6e1b\u3092\u57fa\u8ef8\u3068\u3057\u305f\u5e0c\u5c11\u96e3\u75c5\u306e \u4e88\u9632\u30fb\u6cbb\u7642\u6cd5\u306b\u95a2\u3059\u308b\u57fa\u76e4\u7814\u7a76<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a \u539f \u592a\u4e00\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/li>\n<li>\u7814\u7a76\u8cbb\u540d\uff1a\u65e5\u672c\u8fb2\u82b8\u5316\u5b66\u4f1a<br \/>\n\u7814\u7a76\u8ab2\u984c\u540d\uff1a \u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u4ea2\u9032\u3059\u308b\u65b0\u305f\u306a\u52a0\u5de5\u98df\u54c1\u7d20\u6750\u306e\u7523\u696d\u5fdc\u7528\u7814\u7a76\u958b\u767a<br \/>\n\u7814\u7a76\u4ee3\u8868\u8005\u540d\uff08\u6240\u5c5e\u6a5f\u95a2\u540d\uff09\uff1a \u539f \u592a\u4e00\uff08\u65e9\u7a32\u7530\u5927\u5b66\uff09<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u9175\u6bcd\u767a\u9175\u30cb\u30f3\u30cb\u30af\u304c\u7d30\u80de\u306e\u5065\u5eb7\u3092\u5b88\u308b\u4ed5\u7d44\u307f\u3092\u89e3\u660e \u2014 \u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u6d3b\u6027\u5316\u3059\u308b\u65b0\u305f\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u30dd\u30ea\u30df\u30a2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u91cd\u8981\u6027 \u2014 \u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8 \u30cb\u30f3\u30cb\u30af\u306e\u9175\u6bcd\u767a\u9175\u51e6\u7406\u306b\u3088\u308a\u3001\u7d30\u80de\u4fdd\u8b77\u30b7\u30b9\u30c6\u30e0\u3067\u3042\u308b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u6d3b\u6027\u5316\u4f5c\u7528 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":80657,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[145,60,178],"class_list":["post-80651","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-pressrelease","tag-health","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/80651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/comments?post=80651"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/80651\/revisions"}],"predecessor-version":[{"id":80665,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/80651\/revisions\/80665"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media\/80657"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media?parent=80651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/categories?post=80651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/tags?post=80651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}