{"id":76525,"date":"2024-02-09T13:26:35","date_gmt":"2024-02-09T04:26:35","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=76525"},"modified":"2024-02-09T13:26:35","modified_gmt":"2024-02-09T04:26:35","slug":"frailty-modifies-the-association-of-body-mass-index-with-mortality-among-older-adults-kyoto-kameoka-study%ef%bc%88published-in-clinical-nutrition-january-2024%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/76525","title":{"rendered":"Frailty modifies the association of body mass index with mortality among older adults: Kyoto-Kameoka study\uff08Published in Clinical Nutrition, January 2024\uff09"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n
Journal Title
\n\/\u63b2\u8f09\u30b8\u30e3\u30fc\u30ca\u30eb\u540d<\/td>\n		Clinical Nutrition<\/td>\n<\/tr>\n
Publication Year and Month
\n\/\u63b2\u8f09\u5e74\u6708<\/td>\n		January, 2024<\/td>\n<\/tr>\n
Paper Title
\n\/\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/td>\n		Frailty modifies the association of body mass index with mortality among older adults: Kyoto-Kameoka study<\/td>\n<\/tr>\n
DOI
\n\/\u8ad6\u6587DOI<\/td>\n		10.1016\/j.clnu.2024.01.002<\/a><\/td>\n<\/tr>\n
\u00a0Author of Waseda University
\n\/\u672c\u5b66\u306e\u8457\u8005<\/td>\n		WATANABE, Daiki(Assistant Professor(without tenure), Faculty of Sport Sciences, School of Sport and Sciences):First Author, Correspoinding Author<\/td>\n<\/tr>\n
Related Websites
\n\/\u95a2\u9023Web<\/td>\n		–<\/td>\n<\/tr>\n
Abstract
\n\/\u6284\u9332<\/td>\n		\n

Background & aims<\/h3>\n
The differences in the association of body mass index (BMI) with mortality between older adults with and without frailty remain unclear. This study investigated this association in community-dwelling older adults with and without frailty.<\/div>\n

Methods<\/h3>\n
This prospective study included 10,912 adults aged \u226565 years who provided valid responses to a baseline mail survey questionnaire in the Kyoto-Kameoka Study in Japan. The BMI was calculated based on self-reported height and body weight and classified into four categories: <18.5, 18.5\u201321.4, 21.5\u201324.9, and \u226525.0\u00a0kg\/m2<\/sup>. Frailty was evaluated using the validated Kihon Checklist and defined as a score of 7 or higher out of a possible 25 points. Mortality data were collected from 30 July 2011 to 30 November 2016. Hazard ratios (HR) for all-cause mortality were calculated using a multivariable Cox proportional hazards model.<\/div>\n

Results<\/h3>\n
During the 5.3 year median follow-up period (54,084 person-years), 1352 deaths were recorded. After adjusting for confounders, including lifestyle and medical history, compared with participants with a BMI of 21.5\u201324.9\u00a0kg\/m2<\/sup>, those in the lower BMI category had a higher mortality HR, while those with a higher BMI displayed an inverse association with mortality (<18.5\u00a0kg\/m2<\/sup>: HR: 1.85, 95% confidence interval [CI]: 1.58\u20132.17; 18.5\u201321.4\u00a0kg\/m2<\/sup>: HR: 1.38, 95% CI: 1.21\u20131.58; and \u226525.0\u00a0kg\/m2<\/sup>: HR: 0.80, 95% CI: 0.67\u20130.96). In a model stratified by frailty status, the BMI range with the lowest HR for mortality was 23.0\u201324.0\u00a0kg\/m2<\/sup>\u00a0in non-frail older adults; however, in frail older adults, a higher BMI was inversely associated with mortality.<\/div>\n

Conclusions<\/h3>\n
The relationship between BMI and mortality varies between individuals with and without frailty, with those experiencing frailty potentially benefiting from a higher BMI compared to those without frailty. This study suggests that frailty should be assessed when considering the optimal BMI for the lowest mortality risk among older adults.<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Journal Title \/\u63b2\u8f09\u30b8\u30e3\u30fc\u30ca\u30eb\u540d Clinical Nutrition Publication Year and Month \/\u63b2\u8f09\u5e74\u6708 January, 2024 Paper Title \/\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[218,217],"class_list":["post-76525","post","type-post","status-publish","format-standard","hentry","tag-impact-en","tag-impact"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76525","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/comments?post=76525"}],"version-history":[{"count":1,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76525\/revisions"}],"predecessor-version":[{"id":76526,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76525\/revisions\/76526"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media?parent=76525"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/categories?post=76525"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/tags?post=76525"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}