{"id":76325,"date":"2024-01-19T09:11:41","date_gmt":"2024-01-19T00:11:41","guid":{"rendered":"https:\/\/www.waseda.jp\/inst\/research\/?p=76325"},"modified":"2024-01-19T16:12:35","modified_gmt":"2024-01-19T07:12:35","slug":"%e6%a9%9f%e8%83%bd%e6%80%a7rna%e3%81%ae%e9%85%8d%e5%88%97%e8%a8%ad%e8%a8%88%e3%82%92%e6%94%af%e6%8f%b4%e3%81%99%e3%82%8b%e6%b7%b1%e5%b1%a4%e7%94%9f%e6%88%90%e3%83%a2%e3%83%87%e3%83%abrfamgen","status":"publish","type":"post","link":"https:\/\/www.waseda.jp\/inst\/research\/news\/76325","title":{"rendered":"\u6a5f\u80fd\u6027RNA\u306e\u914d\u5217\u8a2d\u8a08\u3092\u652f\u63f4\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u201cRfamGen\u201d\u306e\u958b\u767a"},"content":{"rendered":"

\u6a5f\u80fd\u6027RNA\u306e\u914d\u5217\u8a2d\u8a08\u3092\u652f\u63f4\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u201cRfamGen\u201d\u306e\u958b\u767a<\/a><\/h1>\n
\u30dd\u30a4\u30f3\u30c8<\/strong><\/h6>\n
\u7279\u5b9a\u306e\u6a5f\u80fd\u3092\u3082\u3064RNA\u914d\u5217\u3092\u5b66\u7fd2\u3057\u3001\u540c\u7b49\u306e\u6a5f\u80fd\u3092\u767a\u63ee\u3059\u308b\u65b0\u898f\u306e\u914d\u5217\u3092\u751f\u6210\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u6ce81\uff09<\/sup>\u201cRfamGen(\u30a2\u30fc\u30eb\u30d5\u30a1\u30e0\u30b8\u30a7\u30f3)\u6ce82\uff09<\/sup>\u201d\u3092\u69cb\u7bc9\u3057\u305f\u3002<\/h5>\n
\u5909\u5206\u30aa\u30fc\u30c8\u30a8\u30f3\u30b3\u30fc\u30c0\uff08VAE\uff09\u6ce83\uff09<\/sup>\u306bRNA\u306e\u6570\u7406\u30e2\u30c7\u30eb\u3067\u3042\u308b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u6ce84\uff09<\/sup>\u3092\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u65b0\u898fRNA\u751f\u6210\u306e\u6027\u80fd\u3092\u9ad8\u3081\u3001\u5c11\u6570\u30c7\u30fc\u30bf\u3067\u3082\u5b89\u5b9a\u7684\u306a\u6027\u80fd\u3092\u5b9f\u73fe\u3057\u305f\u3002<\/h5>\n
RfamGen\u306f\u5165\u529b\u30c7\u30fc\u30bf\u306e\u7279\u5fb4\u3092\u6349\u3048\u306a\u304c\u3089\u60c5\u5831\u3092\u96c6\u7d04\u3057\u3066\u304a\u308a\u3001RNA\u8a2d\u8a08\u306e\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u306b\u6709\u7528\u3067\u3042\u308b\u3002<\/h5>\n
RfamGen\u306b\u3088\u308b\u4eba\u5de5RNA\u306f\u3001\u5b66\u7fd2RNA\u7fa4\u3068\u540c\u7b49\u306e\u69cb\u9020\u3068\u6a5f\u80fd\u3092\u4fdd\u6301\u3057\u3001\u5929\u7136RNA\u3088\u308a\u3082\u9ad8\u3044\u6a5f\u80fd\u6d3b\u6027\u3092\u3082\u3064\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/h5>\n
\u5275\u85ac\u3084\u57fa\u790e\u7814\u7a76\u306b\u304a\u3051\u308bRNA\u8a2d\u8a08\u306e\u30b3\u30b9\u30c8\u524a\u6e1b\u3068\u9ad8\u901f\u5316\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<\/h5>\n

1.\u00a0 \u8981\u65e8<\/h3>\n

\u89d2\u4fca\u8f14 \u6c0f\uff08\u4eac\u90fd\u5927\u5b66iPS\u7d30\u80de\u7814\u7a76\u6240\uff08CiRA\uff09\u672a\u6765\u751f\u547d\u79d1\u5b66\u958b\u62d3\u90e8\u9580 \u5927\u5b66\u9662\u751f\u3001\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662 \u7814\u7a76\u5ba4\u53d7\u3051\u5165\u308c\uff09\u3001\u6d5c\u7530\u9053\u662d \u6559\u6388\uff08\u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662\uff09<\/a>\u3001\u9f4a\u85e4\u535a\u82f1 \u6559\u6388\uff08CiRA\u540c\u90e8\u9580\uff09\u306f\u3001\u76ee\u7684\u306e\u6a5f\u80fd\u3068\u69cb\u9020\u3092\u3082\u3064\u4eba\u5de5RNA\u8a2d\u8a08\u3092\u652f\u63f4\u3059\u308b\u4e16\u754c\u521d\u306e\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u201cRfamGen\u201d\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/p>\n

RfamGen\u306f\u3001\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u3067\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u624b\u6cd5\u306e\u4e00\u3064\u3067\u3042\u308b\u5909\u5206\u30aa\u30fc\u30c8\u30a8\u30f3\u30b3\u30fc\u30c0\uff08VAE\uff09\u3068\u3001RNA\u914d\u5217\u3068\u4e8c\u6b21\u69cb\u9020\u6ce85\uff09<\/sup>\u306e\u60c5\u5831\u304b\u3089\u6a5f\u80fd\u6027RNA\u3092\u5206\u985e\u3059\u308b\u3053\u3068\u306e\u3067\u304d\u308b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u3082\u306e\u3067\u3001\u7279\u5b9a\u306e\u6a5f\u80fd\u3068\u69cb\u9020\u306e\u7279\u5fb4\u3092\u3082\u3064RNA\u7fa4\u306e\u7279\u5fb4\u3092\u5b66\u7fd2\u3057\u3001\u4eba\u5de5\u914d\u5217\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n

\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001RfamGen\u304c\u5b66\u7fd2\u3057\u305fRNA\u7fa4\u3068\u76f8\u540c\u306a\u69cb\u9020\u3068\u6a5f\u80fd\u3092\u3082\u3064RNA\u914d\u5217\u304c\u5b89\u5b9a\u7684\u306b\u751f\u6210\u3067\u304d\u308b\u3053\u3068\u3092\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u306e\u89e3\u6790\u3068\u751f\u5316\u5b66\u5b9f\u9a13\u306e\u4e21\u65b9\u3067\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u3053\u306eRfamGen\u306e\u6027\u80fd\u306f\u3001\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u306b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u9069\u7528\u3057\u305f\u7d50\u679c\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001RfamGen\u306b\u3088\u308b\u751f\u6210\u914d\u5217\u306eRNA\u3092\u5927\u898f\u6a21\u306b\u5408\u6210\u3057\u3001\u7db2\u7f85\u7684\u306b\u305d\u306e\u6d3b\u6027\u3092\u691c\u8a3c\u3057\u305f\u3068\u3053\u308d\u3001\u751f\u6210\u914d\u5217\u306eRNA\u306f\u5929\u7136\u306eRNA\u3088\u308a\u3082\u9ad8\u3044\u6d3b\u6027\u3092\u793a\u3059\u50be\u5411\u3082\u307f\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n

RfamGen\u306b\u3088\u308b\u5b66\u7fd2\u7d50\u679c\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001\u5165\u529b\u30c7\u30fc\u30bf\u306eRNA\u7fa4\u306e\u4e8c\u6b21\u69cb\u9020\u3084\u6a5f\u80fd\u6027\u306e\u30e2\u30c1\u30fc\u30d5\u306a\u3069\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u3092\u3001\u5165\u529b\u30c7\u30fc\u30bf\u306e\u7279\u5fb4\u306e\u5206\u5e03\u3068\u3057\u3066\u52b9\u679c\u7684\u306b\u96c6\u7d04\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u7814\u7a76\u8005\u304c\u5229\u7528\u3057\u305f\u3044RNA\u306e\u7279\u5fb4\u3092\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3057\u3066\u3001\u914d\u5217\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u304c\u5bb9\u6613\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

RfamGen\u306b\u3088\u308a\u4eba\u5de5\u77e5\u80fd\u652f\u63f4\u578b\u306eRNA\u8a2d\u8a08\u304c\u53ef\u80fd\u3068\u306a\u308b\u3053\u3068\u3067\u3001\u5f93\u6765\u306eRNA\u8a2d\u8a08\u3068\u6bd4\u8f03\u3057\u3001\u958b\u767a\u30b3\u30b9\u30c8\u524a\u6e1b\u3068\u9ad8\u901f\u5316\u304c\u5b9f\u73fe\u3057\u3001\u6838\u9178\u533b\u85ac\u3084\u907a\u4f1d\u5b50\u6cbb\u7642\u306a\u3069\u306eRNA\u5275\u85ac\u306e\u7814\u7a76\u958b\u767a\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u7814\u7a76\u6210\u679c\u306f\u30012024\u5e741\u670818\u65e5\u306b\u82f1\u79d1\u5b66\u8a8c\u300cNature Methods\u300d<\/a>\u3067\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

2. \u7814\u7a76\u306e\u80cc\u666f<\/h3>\n

RNA\u5206\u5b50\u306f\u3001\u907a\u4f1d\u5b50\u306e\u8ee2\u5199\u8abf\u7bc0\u3084\u9175\u7d20\u6d3b\u6027\u306a\u3069\u3001\u305d\u306e\u914d\u5217\u306b\u5fdc\u3058\u3066\u3055\u307e\u3056\u307e\u306a\u6a5f\u80fd\u3092\u767a\u63ee\u3057\u3001\u57fa\u790e\u7814\u7a76\u304b\u3089\u533b\u7642\u307e\u3067\u5e45\u5e83\u3044\u5834\u9762\u3067\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5229\u7528\u76ee\u7684\u306b\u9069\u3057\u305f\u6a5f\u80fd\u3092\u3082\u3064RNA\u306e\u5869\u57fa\u914d\u5217\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u306f\u9ad8\u5ea6\u306a\u5c02\u9580\u6027\u3068\u52b4\u529b\u3092\u8981\u3059\u308b\u305f\u3081\u3001RNA\u914d\u5217\u306e\u7279\u5fb4\u3092\u9069\u5207\u306b\u6349\u3048\u3066\u3001\u6a5f\u80fd\u6027RNA\u3092\u52b9\u7387\u7684\u3088\u304f\u8a2d\u8a08\u3067\u304d\u308b\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u624b\u6cd5\u306e\u958b\u767a\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u307e\u3067\u306b\u6a5f\u80fd\u6027RNA\u306e\u8a2d\u8a08\u6cd5\u3068\u3057\u3066\u3001RNA\u9006\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u6ce86\uff09<\/sup>\u304c\u4e3b\u306b\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u624b\u6cd5\u306b\u306f\u3001\u624b\u6cd5\u306e\u6027\u8cea\u4e0a\u3001\u305d\u306e\u6b63\u78ba\u6027\u3084\u6c4e\u7528\u6027\u306b\u3044\u304f\u3064\u304b\u8ab2\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u4eca\u56de\u3001\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001RNA\u306e\u914d\u5217\u3068\u4e8c\u6b21\u69cb\u9020\u3092\u6570\u7406\u7684\u306b\u8a18\u8ff0\u3067\u304d\u308b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3068VAE\u3092\u7d71\u5408\u3057\u305f\u6a5f\u80fd\u6027RNA\u751f\u6210\u306e\u305f\u3081\u306e\u4e16\u754c\u521d\u306e\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30ebRfamGen\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5171\u5206\u6563\u30e2\u30c7\u30eb\u306f\u3001\u914d\u5217\u304b\u3089\u7279\u5b9a\u306e\u4e8c\u6b21\u69cb\u9020\u3092\u691c\u51fa\u3057\u3001\u5e45\u5e83\u3044\u7a2e\u985e\u306eRNA\u3092RNA\u30d5\u30a1\u30df\u30ea\u30fc\u3068\u3057\u3066\u5206\u985e\u3067\u304d\u3001\u30b2\u30ce\u30e0\u914d\u5217\u304b\u3089\u591a\u304f\u306e\u6a5f\u80fd\u6027RNA\u3092\u767a\u898b\u3059\u308b\u3053\u3068\u306b\u9577\u5e74\u4f7f\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u308c\u307e\u3067\u306b\u4eba\u5de5RNA\u306e\u8a2d\u8a08\u306b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u304c\u6d3b\u7528\u3055\u308c\u305f\u4f8b\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306fRNA\u5206\u985e\u306b\u6709\u7528\u306a\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5f93\u6765\u306e\u6280\u8853\u7684\u8ab2\u984c\u3092\u89e3\u6c7a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u307e\u3057\u305f\u3002<\/p>\n

3. \u7814\u7a76\u7d50\u679c<\/h3>\n

1) RNA\u30d5\u30a1\u30df\u30ea\u30fc\u914d\u5217\u3092\u8a2d\u8a08\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30ebRfamGen<\/h4>\n

RfamGen\u306f\u3001\u6a5f\u80fd\u6027RNA\u306e\u751f\u6210\u6027\u80fd\u3092\u9ad8\u3081\u308b\u305f\u3081\u3001VAE\u306bRNA\u306e\u5206\u985e\u306b\u7528\u3044\u3089\u308c\u308b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u7d71\u5408\u3057\u3066\u3044\u307e\u3059\uff08\u56f3\uff11\uff09\u3002<\/p>\n

\u5171\u5206\u6563\u30e2\u30c7\u30eb\u306f\u3001RNA\u306e\u914d\u5217\u3068\u4e8c\u6b21\u69cb\u9020\u306b\u57fa\u3065\u304d\u3001\u8907\u6570\u306eRNA\u914d\u5217\u3069\u3046\u3057\u3092\u4e92\u3044\u306b\u63c3\u3046\u3088\u3046\u306b\u4e26\u3079\u308b\u3053\u3068\uff08\u30de\u30eb\u30c1\u30d7\u30eb\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\uff09\u304c\u3067\u304d\u307e\u3059\u3002RfamGen\u3067\u306f\u3001\u306f\u3058\u3081\u306b\u76ee\u7684\u306e\u6a5f\u80fd\u3092\u3082\u3064\u65e2\u5b58\u306eRNA\u914d\u5217\u7fa4\u3092\u7528\u610f\u3057\u3001\u3053\u308c\u3092\u4e00\u3064\u306eRNA\u30d5\u30a1\u30df\u30ea\u30fc\u3068\u898b\u7acb\u3066\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u914d\u5217\u306b\u5bfe\u3057\u3066\u5171\u5206\u6563\u30e2\u30c7\u30eb\u306b\u3088\u308b\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\u3092\u884c\u3044\u307e\u3059\uff08\u56f31\u5de6\uff09\u3002<\/p>\n

RNA\u7fa4\u306e\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u7d50\u679c\u3092\u3001VAE\u306e\u5165\u529b\u30c7\u30fc\u30bf\u3068\u3057\u3066\u4f7f\u7528\u3057\u307e\u3059\u3002VAE\u3067\u306f\u3001\u5165\u529b\u3057\u305f\u30c7\u30fc\u30bf\u7fa4\u306e\u7279\u5fb4\u3092\u5b66\u7fd2\u3057\u3001\u5165\u529b\u30c7\u30fc\u30bf\u306e\u7279\u5fb4\u3092\u78ba\u7387\u5206\u5e03\u3068\u3057\u3066\u8868\u73fe\u3059\u308b\u300c\u6f5c\u5728\u7a7a\u9593\u300d\u3092\u69cb\u7bc9\u3057\u307e\u3059\u3002RfamGen\u3067\u306f\u3001RNA\u30d5\u30a1\u30df\u30ea\u30fc\u3068\u307f\u306a\u3057\u305fRNA\u7fa4\u306e\u7279\u5fb4\u3092\u78ba\u7387\u5206\u5e03\u3068\u3057\u3066\u8868\u73fe\u3059\u308b\u6f5c\u5728\u7a7a\u9593\u304c\u69cb\u7bc9\u3055\u308c\u307e\u3059\uff08\u56f31\u4e2d\u592e\uff09\u3002<\/p>\n

\u3053\u306e\u6f5c\u5728\u7a7a\u9593\u304b\u3089\u51fa\u529b\u3055\u308c\u308b\u30c7\u30fc\u30bf\u306f\u3001\u5165\u529b\u306b\u7528\u3044\u305fRNA\u7fa4\u306e\u5171\u5206\u6563\u30e2\u30c7\u30eb\u306b\u3088\u308b\u7279\u5fb4\u3092\u793a\u3059\u3088\u3046\u306b\u751f\u6210\u3055\u308c\u307e\u3059\u3002\u51fa\u529b\u30c7\u30fc\u30bf\u3092\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u4ecb\u3057\u3066\u914d\u5217\u306b\u518d\u69cb\u7bc9\u3059\u308b\u3053\u3068\u3067\u3001\u6700\u7d42\u7684\u306b\u76ee\u7684\u306e\u6a5f\u80fd\u3092\u7372\u5f97\u3057\u305f\u4eba\u5de5RNA\u914d\u5217\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\uff08\u56f3\uff11\u53f3\uff09\u3002<\/p>\n

\n

\"\"<\/p>\n

\u56f31 RfamGen\u306e\u6982\u8981<\/p>\n<\/div>\n

2) \u5171\u5206\u6563\u30e2\u30c7\u30eb\u306f\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u306e\u6027\u80fd\u3068\u5b89\u5b9a\u6027\u3092\u9ad8\u3081\u308b<\/h4>\n

RfamGen\u306f\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3068\u4e8c\u6b21\u69cb\u9020\u3092\u5b66\u7fd2\u3057\u307e\u3059\u3002\u305d\u308c\u305e\u308c\u306e\u8981\u7d20\u304c\u751f\u6210\u80fd\u529b\u306b\u3069\u306e\u3088\u3046\u306b\u95a2\u308f\u308b\u304b\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u6bd4\u8f03\u5bfe\u8c61\u3068\u3057\u3066\u6b21\u306e\uff13\u7a2e\u306e\u30e2\u30c7\u30eb\u3092\u7528\u610f\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u2460\u00a0\u00a0 \u5171\u5206\u6563\u30e2\u30c7\u30eb\u306b\u3088\u308b\u5165\u529b\u30c7\u30fc\u30bf\u306b\u542b\u307e\u308c\u308b\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\u306e\u60c5\u5831\u3092\u5229\u7528\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb(GCVAE)<\/p>\n

\u2461\u00a0\u00a0 \u5171\u5206\u6563\u30e2\u30c7\u30eb\u306b\u3088\u308b\u5165\u529b\u30c7\u30fc\u30bf\u306b\u542b\u307e\u308c\u308b\u4e8c\u6b21\u69cb\u9020\u306e\u60c5\u5831\u3092\u5229\u7528\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb<\/p>\n

\u2462\u00a0\u00a0 \u4e8c\u6b21\u69cb\u9020\u3068\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\u306e\u60c5\u5831\u3092\u3044\u305a\u308c\u3082\u5229\u7528\u3057\u306a\u3044\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb<\/p>\n

\u3053\u308c\u30893\u7a2e\u306e\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u3068RfamGen\u306b\u3001\u65e2\u77e5\u306eRNA\u30d5\u30a1\u30df\u30ea\u30fc\u914d\u5217\u3092\u5b66\u7fd2\u3055\u305b\u3001\u30e9\u30f3\u30c0\u30e0\u306b1,000\u306e\u914d\u5217\u3092\u751f\u6210\u3055\u305b\u307e\u3057\u305f\u3002\u305d\u306e\u3046\u3048\u3067\u3001\u5b66\u7fd2\u306b\u7528\u3044\u305fRNA\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5171\u901a\u306e\u69cb\u9020\u3068\u3069\u306e\u7a0b\u5ea6\u3001\u76f8\u540c\u6027\u3092\u3082\u3064\u304b\u3092\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u3067\u8a08\u7b97\u3057\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001RfamGen\u304c\u6700\u3082\u826f\u3044\u30b9\u30b3\u30a2\u3092\u793a\u3059\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u6b21\u306b\u3001\u5b66\u7fd2\u306b\u7528\u3044\u308bRNA\u914d\u5217\u7fa4\u306e\u30b5\u30f3\u30d7\u30eb\u6570\u306e\u5897\u6e1b\u306b\u3088\u308a\u30b9\u30b3\u30a2\u304c\u3069\u306e\u3088\u3046\u306b\u5909\u52d5\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002\u307e\u305a\u3001RfamGen\u306b\u6b21\u3044\u3067\u826f\u3044\u30b9\u30b3\u30a2\u3092\u51fa\u3057\u305f\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\u60c5\u5831\u306e\u307f\u3092\u5229\u7528\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\uff08GCVAE\uff09\u3092\u6bd4\u8f03\u5bfe\u8c61\u3068\u3057\u3066RfamGen\u3092\u691c\u8a0e\u3057\u305f\u7d50\u679c\u3001\u591a\u304f\u306e\u5834\u5408\u3067RfamGen\u304cGCVAE\u3088\u308a\u3082\u9ad8\u30b9\u30b3\u30a2\u3092\u53d6\u308b\u3053\u3068\u3001\u305d\u3057\u3066\u3001\u30b5\u30f3\u30d7\u30eb\u6570\u304c\u5c11\u306a\u3044\u5834\u5408\u3067\u3082RfamGen\u306e\u751f\u6210\u80fd\u529b\u304c\u5b89\u5b9a\u3057\u3066\u767a\u63ee\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\uff08\u56f3\uff12\uff09\u3002<\/p>\n

\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u4e8c\u6b21\u69cb\u9020\u3068\u30a2\u30e9\u30a4\u30f3\u30e1\u30f3\u30c8\u4e21\u65b9\u306e\u5b66\u7fd2\u304c\u91cd\u8981\u3067\u3042\u308a\u3001\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3092\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u54c1\u8cea\u306e\u9ad8\u3044\u4eba\u5de5RNA\u914d\u5217\u3092\u5b89\u5b9a\u7684\u306b\u751f\u6210\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\n

\"\"<\/p>\n

\u56f32 \u30b5\u30f3\u30d7\u30eb\u6570\u306b\u3088\u308b\u751f\u6210\u6027\u80fd\u306e\u5909\u52d5
\n\u8868\u306e\u7e26\u8ef8 Bit Score\uff1aRNA\u30d5\u30a1\u30df\u30ea\u30fc\u914d\u5217\u3089\u3057\u3055<\/p>\n<\/div>\n

3) RfamGen\u306b\u3088\u308b\u6f5c\u5728\u7a7a\u9593\u306e\u5b66\u7fd2<\/h4>\n

\u6b21\u306b\u3001VAE\u306e\u6f5c\u5728\u7a7a\u9593\u304c\u3001\u5b66\u7fd2\u3057\u305fRNA\u914d\u5217\u306e\u7279\u5fb4\u3092\u7684\u78ba\u306b\u53cd\u6620\u3057\u305f\u3082\u306e\u3068\u306a\u3063\u3066\u3044\u308b\u304b\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u6f5c\u5728\u7a7a\u9593\u3092\u4e8c\u6b21\u5143\u306b\u53ef\u8996\u5316\u3057\u305f\u3068\u3053\u308d\u3001RNA\u306e\u4e8c\u6b21\u69cb\u9020\u306b\u307f\u3089\u308c\u308b\u591a\u578b\u9818\u57df\u3084\u3001\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7d50\u5408\u3059\u308b\u914d\u5217 (\u30e2\u30c1\u30fc\u30d5)\u306a\u3069\u3001\u5165\u529b\u30c7\u30fc\u30bf\u3067\u3042\u308bRNA\u914d\u5217\u306e\u7279\u5fb4\u306e\u5206\u5e03\u304c\u3001\u6f5c\u5728\u7a7a\u9593\u306b\u52b9\u679c\u7684\u306b\u96c6\u7d04\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\uff08\u56f3\uff13\uff09\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001RfamGen\u306f\u3001\u4eba\u5de5RNA\u8a2d\u8a08\u652f\u63f4\u30c4\u30fc\u30eb\u3068\u3057\u3066\u6709\u7528\u306a\u3001\u7814\u7a76\u8005\u304c\u76ee\u7684\u306e\u6a5f\u80fd\u3068\u69cb\u9020\u3092\u3082\u3064\u914d\u5217\u3092\u3088\u308a\u8a73\u7d30\u306b\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3067\u304d\u308b\u6027\u80fd\u3082\u3082\u3064\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\n

\"\"<\/p>\n

\u56f33 \u6f5c\u5728\u7a7a\u9593\u306b\u304a\u3051\u308b\u914d\u5217\u60c5\u5831\u306e\u52b9\u679c\u7684\u306a\u96c6\u7d04<\/p>\n<\/div>\n

4) RfamGen\u306f\u9ad8\u78ba\u7387\u306b\u6d3b\u6027\u914d\u5217\u3092\u751f\u6210\u3057\u3001\u9ad8\u6d3b\u6027\u3092\u793a\u3059\u50be\u5411\u304c\u3042\u308b<\/h4>\n

\u3055\u3089\u306b\u3001RfamGen\u3092\u7528\u3044\u305f\u4eba\u5de5RNA\u306e\u6027\u80fd\u3092\u5927\u898f\u6a21\u306a\u751f\u5316\u5b66\u5b9f\u9a13\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001RNA\u5206\u5b50\u306e\u3046\u3061\u81ea\u5df1\u5207\u65ad\u3068\u3044\u3046\u9175\u7d20\u6d3b\u6027\u3092\u3082\u3064\u6570\u767e\u306eRNA\u9175\u7d20\uff08\u30ea\u30dc\u30b6\u30a4\u30e0\uff09\u306e\u914d\u5217\u60c5\u5831\u3092\u65e2\u5b58\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304b\u3089\u53d6\u5f97\u3057\u3001RfamGen\u306e\u5b66\u7fd2\u306b\u4f7f\u7528\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001RfamGen\u304b\u3089\u751f\u6210\u3055\u308c\u305f\u914d\u5217\u304c\u3001\u5b9f\u969b\u306b\u5929\u7136\u306eRNA\u3068\u76f8\u540c\u306a\u69cb\u9020\uff08\u56f34\u5de6\uff09\u3068\u9175\u7d20\u6d3b\u6027\u3092\u3082\u3064\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u304b\u3089\u3001\u5c11\u6570\u306e\u30c7\u30fc\u30bf\u3067\u5b66\u7fd2\u3057\u305f\u5834\u5408\u3082\u3001RfamGen\u304c\u671f\u5f85\u3057\u305f\u914d\u5217\u3092\u751f\u6210\u3067\u304d\u308b\u3053\u3068\u3092\u5b9f\u9a13\u306b\u3088\u3063\u3066\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u307e\u305f\u3001\u4f4e\u5206\u5b50\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u81ea\u5df1\u306eRNA\u914d\u5217\u3092\u5207\u65ad\u3059\u308b\u6d3b\u6027\u3092\u3082\u3064RNA\u9175\u7d20\u3067\u3042\u308bglmS\u30ea\u30dc\u30b6\u30a4\u30e0\u3092\u4f8b\u306b\u3001RfamGen\u306b\u3088\u308a\u65b0\u898f\u306b1,000\u306e\u914d\u5217\u3092\u751f\u6210\u3057\u3001\u5927\u898f\u6a21\u306b\u751f\u6210RNA\u914d\u5217\u306e\u7db2\u7f85\u7684\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001RfamGen\u306f\u9175\u7d20\u6d3b\u6027\u306e\u9ad8\u3044\u914d\u5217\u3092\u9ad8\u78ba\u7387\u306b\u751f\u6210\u3067\u304d\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f(\u56f3\uff14\u53f3)\u3002<\/p>\n

\n

\"\"<\/p>\n

\u56f34 RfamGen\u751f\u6210\u914d\u5217\u306e\u69cb\u9020\u3068\u6a5f\u80fd\u306e\u8a55\u4fa1
\n\u5de6\uff1a\u4e8c\u6b21\u69cb\u9020\u304c\u76f8\u540c\u306a\u751f\u6210\u914d\u5217\u3068\u5929\u7136\u914d\u5217
\n\u53f3\uff1a\u9175\u7d20\u6d3b\u6027\u306e\u6027\u80fd\u5206\u5e03\u306e\u6bd4\u8f03\uff08\u30aa\u30ec\u30f3\u30b8\uff1a\u751f\u6210\u914d\u5217\u7fa4\u3001\u7070\u8272\uff1a\u5929\u7136\u914d\u5217\u7fa4\uff09<\/p>\n<\/div>\n

4. \u307e\u3068\u3081\u3068\u5c55\u671b<\/h3>\n

\u672c\u7814\u7a76\u3067\u306f\u3001RNA\u5206\u985e\u306b\u5229\u7528\u3055\u308c\u308b\u5171\u5206\u6563\u30e2\u30c7\u30eb\u3068\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u3092\u7d71\u5408\u3057\u3001\u4eba\u5de5RNA\u914d\u5217\u8a2d\u8a08\u652f\u63f4\u306b\u7528\u3044\u308b\u3053\u3068\u306e\u3067\u304d\u308bRfamGen\u3092\u69cb\u7bc9\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u3068\u5b9f\u9a13\u306b\u3088\u308b\u6027\u80fd\u8a55\u4fa1\u306b\u3088\u3063\u3066\u3001\u5c11\u6570\u306e\u5165\u529b\u30c7\u30fc\u30bf\u3067\u5b66\u7fd2\u3057\u305f\u5834\u5408\u3067\u3082\u5341\u5206\u306a\u6027\u80fd\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u3084\u3001\u7814\u7a76\u8005\u304c\u751f\u6210\u914d\u5217\u3092\u8a73\u7d30\u306b\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u3001\u5165\u529b\u30c7\u30fc\u30bf\u3088\u308a\u3082\u9ad8\u6027\u80fd\u306a\u4eba\u5de5RNA\u914d\u5217\u3082\u751f\u6210\u3057\u3046\u308b\u3053\u3068\u306a\u3069\u3001RfamGen\u306e\u6709\u7528\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u3001RfamGen\u3092\u6d3b\u7528\u3057\u3066\u3001\u4eba\u5de5RNA\u8a2d\u8a08\u3092\u4f4e\u30b3\u30b9\u30c8\u5316\u3001\u9ad8\u901f\u5316\u3057\u3001\u751f\u7269\u5b66\u3084\u533b\u5b66\u306a\u3069\u5e45\u5e83\u3044\u9818\u57df\u3067RNA\u304c\u6d3b\u7528\u3055\u308c\u308b\u3053\u3068\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

5. \u8ad6\u6587\u540d\u3068\u8457\u8005<\/h3>\n

\u8ad6\u6587\u540d<\/h5>\n

\u201cDeep generative design of RNA family sequences\u201d<\/a>
\nDOI: 10.1038\/s41592-023-02148-8<\/a><\/p>\n

\u30b8\u30e3\u30fc\u30ca\u30eb\u540d<\/h5>\n

Nature Methods<\/p>\n

\u8457\u8005<\/h5>\n

Shunsuke Sumi1,2,3<\/sup>, Michiaki Hamada<\/a>3,4,5,*<\/sup>, Hirohide Saito1,*
\n<\/sup>* : \u8cac\u4efb\u8457\u8005<\/p>\n

\u8457\u8005\u306e\u6240\u5c5e\u6a5f\u95a2<\/h5>\n
    \n
  1. \u4eac\u90fd\u5927\u5b66iPS\u7d30\u80de\u7814\u7a76\u6240\uff08CiRA\uff09<\/li>\n
  2. \u4eac\u90fd\u5927\u5b66\u5927\u5b66\u9662 \u533b\u5b66\u7814\u7a76\u79d1<\/li>\n
  3. \u65e9\u7a32\u7530\u5927\u5b66\u7406\u5de5\u5b66\u8853\u9662<\/a><\/li>\n
  4. \u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6240 \u751f\u4f53\u30b7\u30b9\u30c6\u30e0\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u30aa\u30fc\u30d7\u30f3\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u30e9\u30dc\u30e9\u30c8\u30ea\uff08AIST CBBD-OIL\uff09<\/a><\/li>\n
  5. \u65e5\u672c\u533b\u79d1\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1<\/li>\n<\/ol>\n

    6. \u672c\u7814\u7a76\u3078\u306e\u652f\u63f4<\/h3>\n

    \u672c\u7814\u7a76\u306f\u3001\u4ee5\u4e0b\u306e\u652f\u63f4\u3092\u53d7\u3051\u3066\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

      \n
    • \u79d1\u5b66\u6280\u8853\u632f\u8208\u6a5f\u69cb\uff08JST\uff09 \u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696d CREST\u300c\u30a4\u30ce\u30d9\u30fc\u30b7\u30e7\u30f3\u5275\u767a\u306b\u8cc7\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u57fa\u76e4\u6280\u8853\u306e\u5275\u51fa\u3068\u7d71\u5408\u5316\u300d\u7814\u7a76\u9818\u57df\uff08\u7814\u7a76\u7dcf\u62ec\uff1a\u6804\u85e4\u7a14\uff09\u300cAI\u30a2\u30d7\u30bf\u30de\u30fc\u5275\u85ac\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u300d\uff08\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u6d5c\u7530\u9053\u662d\u3001\u4e3b\u305f\u308b\u5171\u540c\u7814\u7a76\u8005\uff1a\u9f4a\u85e4\u535a\u82f1\u3001\u30b0\u30e9\u30f3\u30c8\u756a\u53f7\uff1aJPMJCR21F1\uff09<\/li>\n
    • \u79d1\u5b66\u6280\u8853\u632f\u8208\u6a5f\u69cb\uff08JST\uff09 \u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696d CREST\u300c\u7d30\u80de\u64cd\u4f5c\u300d\u7814\u7a76\u9818\u57df\uff08\u7814\u7a76\u7dcf\u62ec\uff1a\u5bae\u8107 \u6566\u53f2\uff09\u300c\u6a5f\u80fd\u6027RNA\u30fbRNP\u9032\u5316\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306e\u69cb\u7bc9\u3068\u7d30\u80de\u5236\u5fa1\u6280\u8853\u306e\u958b\u767a\u300d\uff08\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u9f4a\u85e4\u535a\u82f1\u3001\u4e3b\u305f\u308b\u5171\u540c\u7814\u7a76\u8005\uff1a\u8db3\u7acb\u4fca\u543e\u3001\u6d5c\u7530\u9053\u662d\u3001\u30b0\u30e9\u30f3\u30c8\u756a\u53f7\uff1aJPMJCR23B3\uff09<\/li>\n
    • \u65e5\u672c\u5b66\u8853\u632f\u8208\u4f1a\uff08JSPS\uff09\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1 \u7279\u5225\u63a8\u9032\u7814\u7a76<\/li>\n<\/ul>\n

      7. \u7528\u8a9e\u8aac\u660e<\/h3>\n

      \u6ce81\uff09\u00a0 \u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb<\/h5>\n

      \u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u306e\u591a\u5c64\u5316\u3057\u305f\u30cb\u30e5\u30fc\u30e9\u30eb\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u3088\u308a\u60c5\u5831\u306e\u51e6\u7406\u3092\u884c\u3044\u3001\u5b66\u7fd2\u3057\u305f\u30c7\u30fc\u30bf\u306e\u7279\u5fb4\u3092\u3082\u3063\u305f\u30c7\u30fc\u30bf\u3092\u65b0\u305f\u306b\u751f\u6210\u3059\u308b\u30e2\u30c7\u30eb\u306e\u3053\u3068\u3002<\/p>\n

      \u6ce82\uff09\u00a0 RfamGen<\/h5>\n

      \u958b\u767a\u3057\u305f\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u306e\u540d\u79f0\u3002RNA\u30d5\u30a1\u30df\u30ea\u30fc\uff08RNA family\uff09\u914d\u5217\u306e\u751f\u6210\u30e2\u30c7\u30eb\uff08generator\uff09\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u201cRfamGen\u201d\u3068\u540d\u4ed8\u3051\u305f\u3002<\/p>\n

      \u6ce83\uff09\u00a0 \u5909\u5206\u30aa\u30fc\u30c8\u30a8\u30f3\u30b3\u30fc\u30c0\uff08VAE\uff09<\/h5>\n

      \u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u306e\u624b\u6cd5\u306e\u4e00\u3064\u3002\u5165\u529b\u30c7\u30fc\u30bf\u3092\u5143\u306b\u305d\u306e\u7279\u5fb4\u3092\u78ba\u7387\u5206\u5e03\u3068\u3057\u3066\u6f5c\u5728\u7a7a\u9593\u306b\u3068\u3089\u3048\u3001\u5165\u529b\u30c7\u30fc\u30bf\u3068\u4f3c\u305f\u30c7\u30fc\u30bf\u3092\u65b0\u305f\u306b\u751f\u6210\uff08\u51fa\u529b\uff09\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002VAE\u306fVariational Autoencoder\u306e\u7565\u3002<\/p>\n

      \u6ce84\uff09\u00a0 \u5171\u5206\u6563\u30e2\u30c7\u30eb<\/h5>\n

      RNA\u914d\u5217\u306e\u76f8\u540c\u6027\u3092\u8a55\u4fa1\u3059\u308b\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306b\u7528\u3044\u308b\u30e2\u30c7\u30eb\u3002\u30b2\u30ce\u30e0\u4e2d\u306e\u6a5f\u80fd\u6027RNA\u306e\u63a2\u7d22\u306b\u9577\u5e74\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u3002\u5171\u5206\u6563\u30e2\u30c7\u30eb\u306b\u3088\u308a\u3001RNA\u914d\u5217\u306f\u6570\u5343\u306eRNA\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5206\u985e\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

      \u6ce85\uff09\u00a0 \u4e8c\u6b21\u69cb\u9020<\/h5>\n

      1\u672c\u9396RNA\u306e\u914d\u5217\u306b\u5fdc\u3058\u3066\u5c40\u6240\u7684\u306b\u5f62\u6210\u3055\u308c\u308b\u5869\u57fa\u5bfe\u69cb\u9020\u3002<\/p>\n

      \u6ce86\uff09 RNA\u9006\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0<\/h5>\n

      RNA\u306e\u69cb\u9020\u304b\u3089\u914d\u5217\u3092\u8a08\u7b97\u3059\u308b\u65b9\u6cd5\u3002\u914d\u5217\u304b\u3089\u69cb\u9020\u3092\u8a08\u7b97\u3059\u308b\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u306e\u9006\u306e\u6d41\u308c\u306e\u305f\u3081\u3001\u9006\u30d5\u30a9\u30fc\u30eb\u30c7\u30a3\u30f3\u30b0\u3068\u547c\u3070\u308c\u308b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

      \u6a5f\u80fd\u6027RNA\u306e\u914d\u5217\u8a2d\u8a08\u3092\u652f\u63f4\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u201cRfamGen\u201d\u306e\u958b\u767a \u30dd\u30a4\u30f3\u30c8 \u7279\u5b9a\u306e\u6a5f\u80fd\u3092\u3082\u3064RNA\u914d\u5217\u3092\u5b66\u7fd2\u3057\u3001\u540c\u7b49\u306e\u6a5f\u80fd\u3092\u767a\u63ee\u3059\u308b\u65b0\u898f\u306e\u914d\u5217\u3092\u751f\u6210\u3059\u308b\u6df1\u5c64\u751f\u6210\u30e2\u30c7\u30eb\u6ce81\uff09\u201cRfamGen(\u30a2\u30fc\u30eb\u30d5\u30a1\u30e0\u30b8\u30a7\u30f3)\u6ce82 […]<\/p>\n","protected":false},"author":4,"featured_media":76326,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[145,178],"class_list":["post-76325","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-pressrelease","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/comments?post=76325"}],"version-history":[{"count":2,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76325\/revisions"}],"predecessor-version":[{"id":76334,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/posts\/76325\/revisions\/76334"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media\/76326"}],"wp:attachment":[{"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/media?parent=76325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/categories?post=76325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waseda.jp\/inst\/research\/wp-json\/wp\/v2\/tags?post=76325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}