著作物


2016年度
Tahara Y, Yokota A, Shiraishi T, Yamada S, Haraguchi A, Shinozaki A,Shibata S
In vitro and in vivo Phase Changes of the Mouse CircadianClock by Oxidative Stress, Journal of Circadian Rhythms,
2016, 14:1-7
Sasaki H, Hattori Y, Ikeda Y, Kamagata M, Iwami S, Yasuda S, Tahara Y, Shibata S.
Forced rather than voluntary exercise entrains peripheral clocks via a corticosterone/noradrenaline increase in PER2::LUC mice.
Sci Rep. 2016 Jun 8;6:27607.
Sasaki H, Hattori Y, Ikeda Y, Kamagata M, Iwami S, Yasuda S, Shibata S.
Phase shifts in circadian peripheral clocks caused by exercise are dependent on the feeding schedule in PER2::LUC mice.
Chronobiol Int. 2016 Apr 28:1-14.
Tahara Y, Aoyama S, Shibata S.
The mammalian circadian clock and its entrainment by stress and exercise.
J Physiol Sci. 2016 Apr 15.
2015年度
Katamune C, Koyanagi S, Shiromizu S, Matsunaga N, Shimba S, Shibata S,Ohdo S.
Different roles of negative and positive components of the circadian clock in oncogene-induced neoplastic transformation.
J Biol Chem. 2016 Mar 9.
Tahara Y, Shibata S.
Circadian rhythms of liver physiology and disease: experimental and clinical evidence.
Nat Rev Gastroenterol Hepatol. 2016 Feb 24.
Nakamura Y, Nakano N, Ishimaru K, Ando N, Katoh R, Suzuki-Inoue K, Koyanagki S, Ogawa H, Okumura K, Shibata S, Nakao A.
Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock.
J Allergy Clin Immunol., J Allergy Clin Immunol. 2015 Nov 7.
Moriya S, Tahara Y, Sasaki H, Ishigooka J, Shibata S.
Phase-delay in the light-dark cycle impairs clock gene expression and levels of serotonin, norepinephrine, and their metabolites in the mouse hippocampus and amygdala.
Sleep Med. 2015 Nov;16(11):1352-9.
Hamaguchi Y, Tahara Y, Hitosugi M, Shibata S.
Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise.
J Biol Rhythms. 2015 Oct 14
Tanabe K, Kitagawa E, Wada M, Haraguchi A, Orihara K, Tahara Y, Nakao A, Shibata S.
Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model.
Sci Rep. 2015 Sep 30;5:14424
Hamaguchi Y, Tahara Y, Kuroda H, Haraguchi A, Shibata S.
Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions.
Sci Rep. 2015 Sep 23;5:14207
Yoshida D, Aoki N, Tanaka M, Aoyama S, Shibata S.
The circadian clock controls fluctuations of colonic cell proliferation during the light/dark cycle via feeding behavior in mice.
Chronobiol Int,2015 Oct;32(8):1145-55
Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A.
Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.
J Invest Dermatol,2015 Aug 20
Furutani A, Ikeda Y, Itokawa M, Nagahama H, Ohtsu T, Furutani N, Kamagata M, Yang ZH, Hirasawa A, Tahara Y, Shibata S.
Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120.
PLoS ONE,2015 Jul 10,10:e0132472
Yu Tahara, Takuya Shiraishi, Yosuke Kikuchi, Atsushi Haraguchi, Daisuke Kuriki, Hiroyuki Sasaki, Hiroaki Motohashi, Tomoko Sakai & Shigenobu Shibata
Entrainment of the mouse circadian clock by sub-acute physical and psychological stress
Scientific Reports. 2015 June 15, Article number:11417
Sasaki H, Hattori Y, Ikeda Y, Kamagata M, Shibata S
Eating meals before wheel-running exercise attenuate high fat diet-driven obesity in mice under two meals per day schedule.
Chronobiol Int. 2015 Jun;32(5):677-86.
Moriya S, Tahara Y, Sasaki H, Ishigooka J, Shibata S.
Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice.
Neuroscience Research. 2015 May 27
Nakao A, Nakamura Y, Shibata S.
The circadian clock functions as a potent regulator of allergic reaction.
Allergy.2015 May;70(5):467-73
Hamada T, Miyakawa K, Kushige H, Shibata S, Kurachi S.
Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.
J Physiol Sci. 2015 Apr 7
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2014年度
Yokota S, Nakamura K, Ando M, Kamei H, Hakuno F, Takahashi S, Shibata S.
Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver
FEBS Open Bio. 2014 Oct 22;4:905-14
Ikeda Y, Sasaki H, Ohtsu T, Shiraishi T, Tahara Y, Shibata S.
Feeding and adrenal entrainment stimuli are both necessary for normal circadian oscillation of peripheral clocks in mice housed under different photoperiods.
Chronobiol Int.2015 Mar;32(2):195-210
Narishige S, Kuwahara M, Shinozaki A, Okada S, Ikeda Y, Kamagata M, Tahara Y, Shibata S.
Effects of caffeine on circadian phase, amplitude, and period evaluated in cells in vitro and peripheral organs in vivo in PER2:LUCIFERASE mice.
Br J Pharmacol.2014 Dec;171(24):5858-69
Aoki N, Yoshida D, Ishikawa R, Ando M, Nakamura K, Tahara Y, Shibata S.
A single daily meal at the beginning of the active or inactive period inhibits food deprivation-induced fatty liver in mice.
Nutr Res. 2014 Jul;34(7):613-22
Okamura A, Koyanagi S, Dilxiat A, Kusunose N, Chen JJ, Matsunaga N, Shibata S, Ohdo S.
Bile Acid-regulated Peroxisome Proliferator-activated Receptor-α (PPARα) Activity Underlies Circadian Expression of Intestinal Peptide Absorption Transporter PepT1/Slc15a1.
J Biol Chem. 2014 Sep 5;289(36):25296-305
Sasaki H, Ohtsu T, Ikeda Y, Tsubosaka M, Shibata S.
Combination of meal and exercise timing with a high-fat diet influences energy expenditure and obesity in mice.
Chronobiol Int. 2014 Nov;31(9):959-75
Haraguchi A, Aoki N, Ohtsu T, Ikeda Y, Tahara Y, Shibata S.
Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.
Chronobiol Int. 2014 Oct;31(8):935-44
Moriya S, Tahara Y, Sasaki H, Hamaguchi Y, Kuriki D, Ishikawa R, Ishigooka J, Shibata S.
Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus.
J Pharmacol Sci. 2014; 125(3):329-32
Ohnishi N, Tahara Y, Kuriki D, Haraguchi A, Shibata S.
Warm water bath stimulates phase-shifts of the peripheral circadian clocks in PER2::LUCIFERASE mouse.
PLoS One. 2014 Jun 16;9(6):e100272
Nakamura Y, Ishimaru K, Tahara Y, Shibata S, Nakao A.
Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice.
J Immunol Res. 2014; 2014:474217
Kyoko OO, Kono H, Ishimaru K, Miyake K, Kubota T, Ogawa H, Okumura K, Shibata S, Nakao A.
Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis.
PLoS One. 2014 May 20;9(5):e98016
Aoki N, Watanabe H, Okada K, Aoki K, Imanishi T, Yoshida D, Ishikawa R, Shibata S.
Involvement of 5-HT₃ and 5-HT₄ receptors in the regulation of circadian clock gene expression in mouse small intestine.
J Pharmacol Sci. 2014; 124(2):262-75.
Tahara Y, Shibata S.
Chrono-biology, Chrono-pharmacology, and Chrono-nutrition.
J Pharmacol Sci. Review, 2014; 124(3):320-35
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2013年度
Nakamura Y, Nakano N, Ishimaru K, Hara M, Ikegami T, Tahara Y, Katoh R, Ogawa H, Okumura K, Shibata S, Nishiyama C, Nakao A.
Circadian Regulation of Allergic Reaction by the Mast Cell Clock in mice.
J Allergy Clin Immunol. 2014; 133(2):568-75
Horikawa K., Fuji K., Fukazawa Y., Shibata S.,
Two distinct serotonin receptors co-mediate non-photic signals to the circadian clock.
J Pharmacol Sci. 2013; 123(4):402-6
Tahara Y., Shibata S.
Chronobiology and nutrition.
Neuroscience. 2013; 253:78-88
Cermakian N, Lange T, Golombek D, Sarkar D, Nakao A, Shibata S, Mazzoccoli G.
Crosstalk between the circadian clock circuitry and the immune system.
Chronobiol Int. 2013; 30(7):870-88
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2012年度
Itokawa M, Hirao A, Nagahama H, Otsuka M, Ohtsu T, Furutani N, Hirao K, Hatta T, Shibata S.
Time-restricted feeding of rapidly digested starches causes stronger entrainment of the liver clock in PER2::LUCIFERASE knock-in mice.
Nutr Res. 2013 Feb;33(2):109-19
Kuroda H, Tahara Y, Saito K, Ohnishi N, Kubo Y, Seo Y, Otsuka M, Fuse Y, Ohura Y, Hirao A, Shibata S.
Meal frequency patterns determine the phase of mouse peripheral circadian clocks.
Scientific Reports. 2012;2:711
Takita E, Yokota S, Tahara Y, Hirao A, Aoki N, Nakamura Y, Nakao A, Shibata S.
Biological clock dysfunction exacerbates contact hypersensitivity in mice.
Br J Dermatol. 2013 Jan;168(1):39-46
Fuse Y, Hirao A, Kuroda H, Otsuka M, Tahara Y, Shibata S.
Differential roles of breakfast only (one meal per day) and a bigger breakfast with a small dinner (two meals per day) in mice fed a high-fat diet with regard to induced obesity and lipid metabolism.
J Circadian Rhythms. 2012 May 15;10(1):4
Tahara Y, Kuroda H, Saito K, Nakajima Y, Kubo Y, Ohnishi N, Seo Y, Otsuka M, Fuse Y, Ohura Y, Komatsu T, Moriya Y, Okada S, Furutani N, Hirao A, Horikawa K, Kudo T, Shibata S.
In vivo monitoring of peripheral circadian clocks in the mouse.
Current Biology. 2012 Jun 5;22(11):1029-34
Uchida Y, Osaki T, Yamasaki T, Shimomura T, Hata S, Horikawa K, Shibata S, Todo T, Hirayama J, Nishina H.
Involvement of the stress kinase mitogen-activated protein kinase kinase 7 in the regulation of the mammalian circadian clock.
J Biol Chem. 2012 Mar 9;287(11):8318-26
Hirao A, Furutani N, Nagahama H, Itokawa M, Shibata S.
The Protective and Recovery Effects of Fish Oil Supplementation on Cedar Pollen-Induced Allergic Reactions in Mice.
Food Nutrition and Sciences, 3(1):40-47, 2012. doi:10.4236/fns.2012.31008
Kubo Y, Tahara Y, Hirao A, Shibata S.
2,2,2-Tribromoethanol phase-shifts the circadian rhythm of the liver clock in Per2::Luciferase knockin mice: lack of dependence on anesthetic activity.
J Pharmacol Exp Ther. 2012 Mar;340(3):698-705
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2011年度
Okamoto M, Irii H, Tahara Y, Ishi H, Hirao A, Udagawa H, Hiramoto M, Yasuda K, Takanishi A, Shibata S, Shimizu I.
Synthesis of new [6]-gingerol analog and its protective effect on the development of metabolic syndrome in high-fat diet-fed mice.
J. Medicinal Chemistry. 2011 Sep 22;54(18):6295-304.
Sato-Mito N, Shibata S, Sasaki S, Sato K.
Dietary intake is associated with human chronotype as assessed by both morningness-eveningness score and preferred midpoint of sleep in young Japanese women.
Int J Food Sci Nutr. 2011 Aug;62(5):525-32
Sato-Mito N, Sasaki S, Murakami K, Okubo H, Takahashi Y, Shibata S, Yamada K, Sato K; the Freshmen in Dietetic Courses Study II group.
The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women.
Sleep Med. 2011 Mar;12(3):289-94
Hayasaka N, Aoki K, Kinoshita S, Yamaguchi S, Wakefield JK, Tsuji-Kawahara S, Horikawa K, Ikegami H, Wakana S, Murakami T, Ramabhadran R, Miyazawa M, Shibata S.
Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice.
PLoS One. 2011 Mar 9;6(3):e17655.
Nakamura Y, Harama D, Shimokawa N, Hara M, Suzuki R, Tahara Y, Ishimaru K, Katoh R, Okumura K, Ogawa H, Shibata S, Nakao A.
The circadian clock gene Period2 regulates a time of day-dependent variation in cutanenous anaphylactic reaction.
Journal of Allergy and Clinical Immunology. 2011 Apr;127(4):1038-45.
Yu Tahara, Makiko Otsuka, Yuta Fuse, Akiko Hirao, and Shigenobu Shibata
Refeeding after fasting elicits insulin-dependent regulation of Per2 and Rev-erba with shifts in the liver clock.
J Biological Rhythms. 2011 Jun;26(3):230-40
Naoto Hayasaka, Kazuyuki Aoki, Saori Kinoshita, Shoutaroh Yamaguchi, John K. Wakefield, Sachiyo Tsuji-Kawahara, Kazumasa Horikawa, Hiroshi Ikegami, Shigeharu Wakana, Takamichi Murakami, Ram Ramabhadran, Masaaki Miyazawa and Shigenobu Shibata.
Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice.
PLoS One. 2011 Mar 9;6(3):e17655

Sato-Mito N, Sasaki S, Murakami K, Okubo H, Takahashi Y, Shibata S, Yamada K, Sato K; the Freshmen in Dietetic Courses Study II group.  The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women. Sleep Med. 12(3):289-294. 2011.

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2010年度

Sato-Mito N, Sasaki S, Murakami K, Okubo H, Takahashi Y, Shibata S, Yamada K, Sato K, and the Freshmen in Dietetic Courses Study-group.

The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women.
Sleep Medicine, 2010, in press
Hirao A, Nagahama H, Tsuboi T, Hirao M, Tahara Y, and Shibata S,
Combination of starvation interval and food volume determines the phase of liver circadian rhythm in Per2::luc knock-in mice under two meals per day feeding
.
Am J. Physiology,2010
 Matsumoto E, Ishihara A, Tamai S, Nemoto A, Iwase K, Hiwasa T, Shibata S, Takiguchi M.
Time-of-day and nutrients in feeding govern daily expre
ssion rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liver.

J Biol Chem. 2010 Aug 18.
Shibata S, Tahara Y, Hirao A.
The adjustment and manipulation of biological rhythms by light, nutrition, and abused drugs.

Adv Drug Deliv Rev. Jun 23.,2010 review
Shibata S, Hirao A, Tahara Yu.
Restricted feeding-induced entrainment of activity rhythm and peripheral clock rhythm .
Sleep and Biological Rhythms, 8, 18-27,2010 review
Ebisawa T, Numazawa K, Shimada H, Izutsu H, Sasaki T, Kato N, Tokunaga K, Mori A, Honma K, Honma S, Shibata S.
Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood.

Neurosci Res. 66:223-227.2010

 Ninomiya M, Numakawa T, Adachi N, Furuta M, Chiba S, Richards M, Shibata S, Kunugi H.
Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF.
Neurosci Lett. 476:104-109. 2010 .

Kajiyama Y, Iijima Y, Chiba S, Furuta M, Ninomiya M, Izumi A, Shibata S, Kunugi H. Prednisolone causes anxiety- and depression-like behaviors and altered expression of apoptotic genes in mice hippocampus.
Prog Neuropsychopharmacol Biol Psychiatry. 34:159-165.2010
Hamada T, Shibata S.
The role of GABAergic neuron on NMDA- and SP-induced phase delays in the suprachiasmatic nucleus neuronal activity rhythm in vitro.

Neurosci Lett. 468:344-347. 2010
Tahara Y, Hirao A, Moriya T, Kudo T, Shibata S.
Effects of medial hypothalamic lesions on feeding-induced entrainment of locomotor activity and liver Per2 expression in Per2::luc mice.
J Biol Rhythms. 25:9-18.2010
Yamamura Y, Yano I, Kudo T, Shibata S.
Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver.

Chronobiol Int. 27:213-232.2010
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2009年度
Hirao A, Tahara Y, Kimura I, Shibata S.
A balanced diet is necessary for proper entrainment signals of the mouse liver clock.PLoS One. 4:e6909, 2009.
Mistlberger RE, Buijs RM, Challet E, Escobar C, Landry GJ,
Kalsbeek A, Pevet P, Shibata S.
Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al. J Circadian Rhythms. 7:11, 2009.

Moriya T, Aida R, Kudo T, Akiyama M, Doi M, Hayasaka N, Nakahata N, Mistlberger R, Okamura H, Shibata S.
The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice.
Eur J Neurosci. 29:1447-1460. 2009

Kudo T, Tamagawa T, Shibata S.
Effect of chronic ethanol exposure on the liver of Clock-mutant mice.
J Circadian Rhythms. 7:4., 2009

Mistlberger RE, Buijs RM, Challet E, Escobar C, Landry GJ, Kalsbeek A, Pevet P, Shibata S. 
Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice.

J Circadian Rhythms. 7, 3. ,2009, review
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2008年度
Kudo T, Kawashima M, Tamagawa T, Shibata S. “Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet.” Am J Physiol Endocrinol Metab. 2008 Jan

Iwahana E, Karatsoreos I, Shibata S, Silver R.
Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice.
Horm. Behav.53,422-430.2008

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2007年度
Iwahana E , Hamada T, Uchida A, Shibata S “Differential effect of lithium on the circadian oscillator in young and old hamsters.” Biochem Biophys Res Commun. 2007 Jan 18
Miyakawa K, Uchida A, Shiraki T, Teshima K, Takeshima H, Shibata S.“ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle. ” Biochem Biophys Res Commun. 2007 Jan 18
Hayasaka N , Yaita T, Kuwaki T, Honma S, Honma KI, Kudo T, Shibata S. Optimization of Dosing Schedule of Daily Inhalant Dexamethasone to Minimize Phase-shifting of Clock Gene Expression Rhythm in the Lungs of the Asthma Mouse Model.” Endocrinology, Apr 5 2007
Wakatsuki Y, Kudo T, Shibata S. “Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice.” Eur J Neurosci. 2007 Apr
Shirai H, Oishi K, Kudo T, Shibata S, Ishida N. “PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders.” Biochem Biophys Res Commun. 2007 Apr 9
Kudo T, Tamagawa T, Kawashima M, Mito N, Shibata S. “Attenuating Effect of Clock Mutation on Triglyceride Contents in the ICR Mouse Liver under a High-Fat Diet.” J Biol Rhythms. 2007 Aug
Ishihara A, Matsumoto E, Horikawa K, Kudo T, Sakao E, Nemoto A, Iwase K, Sugiyama H, Tamura Y, Shibata S, Takiguchi M. “Multifactorial regulation of daily rhythms in expression of the metabolically responsive gene spot14 in the mouse liver.” J Biol Rhythms. 2007 Aug
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2006年度
 Hoshino K, Wakatsuki Y, Iigo M, Shibata S .
Circadian Clock mutation in dams disurupts nursing behavior and growth pups. Endocrinology. 147, 1916-1923.2006
Miyakawa K, Uchida A, Shiraki T, Teshima K, Takeshima H, Shibata S “ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle.” Neuropharmacology. 2006 Dec 27
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2005年度
Yokota S, Moriya T, Shibata S. "Inhibitory Action of 5-HT(1A) Agonist MKC-242 on Triazolam-Induced Phase Advances in Hamster Circadian Activity Rhythms." J Pharmacol Sci. 2005 May;98(1):103-6.
Iijima M, Yamaguchi S, van der Horst GT, Bonnefont X, Okamura H, Shibata S. "Altered food-anticipatory activity rhythm in Cryptochrome- deficient mice." Neurosci Res. 2005 Jun;52(2):166-73.
Horikawa K, Minami Y, Iijima M, Akiyama M and Shibata S. “Rapid damping of food-entrained circadian rhythm of Clock gene expression in clock-defective peripheral tissues under fasting conditions” Neuroscience. 2005 Jun 14
Teshima K, Minoguchi M, Tounai S, Ashimori A, Eguchi J, Charles N Allen and Shibata S. “Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats” Br J Pharmacol. 2005 Jun 2
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2004年度
Iwahana E, Akiyama M, Miyakawa K, Uchida A, Kasahara J, Fukunaga K, Hamada T, Shibata S. " Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei."Eur J Neurosci. 2004 Apr;19(8):2281-7.
Udo R, Hamada T, Horikawa K, Iwahana E, Miyakawa K, Otsuka K, Shibata S." The role of Clock in the plasticity of circadian entrainment." BiochemBiophys Res Commun. 2004 Jun 11;318(4):893-8.
Kudo T, Akiyama M, Kuriyama K, Sudo M, Moriya T, Shibata S."Night-time restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver. "Diabetologia. 2004 Aug;47(8):1425-36.Epub 2004 Jul 29.
Kuriyama K, Sasahara K, Kudo T, Shibata S " Daily injection of insulin attenuated impairment of liver circadian clock oscillation in the streptozotocin-treated diabetic mouse" FEBS Lett. 2004 Jul:16 Volume 572, Issue 1-3, pp. 206-210
Kudo T, Nakayama E, Suzuki S, Akiyama M, Shibata S. "Cholesterol Diet Enhances Daily Rhythm of Pai-1 mRNA in the Mouse Liver." American Journal of Physiology Endocrinology and metabolism. 2004 Oct:287(4):E644-51
Horikawa K, Shibata S. "Phase-resetting response to (+)8-OH-DPAT, a serotonin 1A/7 receptor agonist, in the mouse in vivo." Neurosci Lett. 2004 Sep 23;368(2):130-4.
Shibata S. "Neural regulation of the hepatic Circadian rhythm." Anat Rec. 2004 Sep 3;280A(1):901.
Akiyama M, Yuasa T, Hayasaka N, Horikawa K, Sakurai T, Shibata S. “Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice.” Eur J Neurosci. 2004 Dec;20(11):3054-62.
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2003年度
Mutoh T, Shibata S, Korf HW, Okamura H. "Melatonin modulates the light-induced sympathoexcitation and vagal suppression with participation of the suprachiasmitic nucleus in mice." J Physiol, 547.1,pp.317-332 2003
Moriya T, Ikeda M, Teshima K, Hara R, Kuriyama K, Yoshioka T, N Allen C, Shibata S. "Facilitation of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor transmission in the suprachiasmatic nucleus by aniracetam enhances photic responses of the biological clock in rodents." J. Neurochem 2003 May;85(4):978-987.
Akiyama M, Minami Y, Kuriyama K, Shibata S. "MAP kinase-dependent induction of clock gene expression by alpha(1)-adrenergic receptor activation." FEBS Lett. 2003 May 8;542(1-3):109-14
Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, Ohdo S, Okamura H, Shibata S. "Adregergic regulation of clock gene expression in the mouse liver." Proc Natl Acad Sci USA 2003 May. vol.100 no.11 6795-6800
Sakao E, Ishihara A, Horikawa K, Akiyama M, Arai M, Kato M, Seki N, Fukunaga K, Shimizu-Yabe A, Iwase K, Ohtsuka S, Sato T, Kohno Y, Shibata S, Takiguchi M. "Two-peaked synchronization in day/night expression rhythms of the fibrinogen gene cluster in the mouse liver." J Biol Chem. 2003 Aug 15;278(33):30450-7.Epub 2003 May 14.
Sudo M, Sasahara K, Moriya T, Akiyama M, Hamada T, Shibata S. "Constant Light Housing Attenuates Circadian Rhythms of mPer2 mRNA and mPER2 Protein Expression in the Suprachiasmatic Nucleus of Mice." Neuroscience.2003;121(2):493-9.
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2002年度
Aida R., Moriya T., Araki M., Akiyama M., Wada K., Wada E., Shibata S. Gastrin-releasing peptide mediates photicentrainable signals to the dorsal subsets of the suprachiasmatic nucleus via Induction of Period gene in mice. Mol. Pharmacol. 2002 Jan;61(1):26-34.
Nishi M, Hashimoto K, Kuriyama K, Komazaki S, Kano M, Shibata S, Takeshima H. Motor discoordination in mutant mice lacking junctophilin type 3. BiochemBiophys Res Commun. 2002 Mar 29;292(2):318-24.
Takahashi S, Yoshinobu Y, Aida R, Shimomura H, Akiyama M, Moriya T, Shibata S. Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice. J Neurosci Res. 2002 May 15;68(4):470-8.
Minami Y, Furuno K, Akiyama M, Moriya T, Shibata S. Pituitary adenylate cyclase-activating polypeptide produces a phase shift associated with induction of mPer expression in the mouse suprachiasmatic nucleus. Neuroscience. 2002;113(1):37-45.
Minami Y. Horikawa K, Akiyama M, Shibata S. Restricted feeding induces daily expression of clock genes and Pai-1 mRNA in the heart of Clock mutant mice. FEBS Lett. 2002 Aug 28;526(1-3):115-8.
Iijima M, Nikaido T, Akiyama M, Moriya T, Shibata S. Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse. Eur J Neurosci. 2002 Sep;16(5):921-9
Nisikawa Y, Shimazoe T, Shibata S, Watanabe S. Time-dependent effect of glutamate on long-term potentiation in the suprachiasmatic nucleus of rats. J Pharmacol. 2002 Oct;90(2):201-4.
Fukunaga K, Horikawa K, Shibata S, Takeuchi Y, Miyamoto E. Ca2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin. J Neurosci Res. 2002 Dec 15;70(6):799-807.
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2001年度
Wakamatsu, H., Takahashi, S., Moriya, T.,. Inouye, S-I., Okamura, H., Akiyama, M. and Shibata, S. Additive effect of mPer1 and 2 antisense oligonucleotides on light-induced phase shift. Neuroreport. 2001 Jan 22;12(1):127-31.
Yamaguchi,S., Kobayashi,M., Mitsui,S., Ishida,Y., van der Horst, G.T.J., Suzuki,M., Shibata,S., Okamura H., Real time monitoring of clock gene expression in the living mouse. Nature. 2001 409,684.
Wakamatsu H., Yoshinobu Y., Aida R., Moriya T., Akiyama M. and Shibata S., Restricted feeding-induced activity rhythm is associated with expression rhythm of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus in mice. Eur J Neurosci. 2001 Mar;13(6):1190-6.
Shimomura H., Moriya T., Sudo M., Wakamatsu H., Akiyama M., Shibata S., Differential Daily Expression of Per1 and Per2 mRNA in the Suprachiasmatic Nucleus of Fetal and Early Postnatal Mice. Eur J Neurosci. 2001 Feb;13(4):687-93.
Nikaido T., Akiyama M., Moriya T., and Shibata S., Sensitized Increase of Period Gene Expression in the Mouse Caudate/Putamen Caused by Repeated Injection of Methamphetamine. Mol Pharmacol. 2001 Apr;59(4):894-900.
Hara R., Wan K., Wakamatsu H., Aida R., Kuriyama K., Moriya T. , Akiyama M. and Shibata S., Restricted feeding entrains circadian clocks in the mouse liver without participation of suprachiasmatic nucleus. Genes Cells. 2001 Mar;6(3):269-78.
Yokota, S-I., Yamamoto, M., Moriya, T., Akiyama, M., Fukunaga K., Miyamoto, E. and Shibata, S. Involvement of Calcium-calmodulin Protein Kinase but not of Mitogen-activated Protein Kinase in Light-induced Phase Delay and Per Gene Expression in the Suprachiasmatic Nucleus of Hamster. J Neurochem. 2001 Apr;77(2):618-27.
Yamamoto S, Shigeyoshi Y, Ishida Y, Fukuyama T, Yamaguchi S, Yagita K, Moriya T, Shibata S, Takashima N, Okamura H. Expression of the Per1 gene in the hamster: Brain atlas and circadian characteristics in the suprachiasmatic nucleus. J Comp Neurol. 2001 Feb 19;430(4):518-32.
Akiyama, M. Minami, Y., Nakajima, T., Moriya, T. and Shibata, S. Calcium and pituitary adenylate cyclase-activating polypeptide induced expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture. J Neurochem. 2001 Aug;78(3):499-508.
Takahashi S., Yokota S-I., Hara R., Kobayashi T., Akiyama M., Moriya T., Shibata S. Physical and Inflammatory Stressors Elevate Circadian Clock Gene mPer1 mRNA Levels in the Paraventricular Nucleus of the Mouse. Endocrinology. 2001 Nov;142(11):4910-7.
Asai M., Yoshinobu Y., Kaneko S., Mori A., Nikaido T., Moriya T., Akiyama M., Shibata S., Circadian profile of Per Gene mRNA expression in the suprachiasmatic nucleus, paraventricular nucleus, and pineal body of aged rats. J Neurosci Res. 2001 Dec 15;66(6):1133-9.
1Asai M., Yamaguchi S., Isejima H., Jonouchi M., Moriya T., Shibata S., Kobayashi M., Okamura H., Visualization of mPer1 transcription in vitro: NMDA induces a rapid phase shift of mPer1 gene in cultured SCN. Curr Biol. 2001 Oct 2;11(19):1524-7.
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2000年度
Stork O, Ji F, Kaneko K, Stork S, Yoshinobu Y, Moriya T, Shibata S, Obata K. Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65. Brain Res. 2000 May 19;865(1):45-58.
Kouzu,Y., Moriya,T., Takeshima,H., Yoshioka,T., Shibata,S., Mutant mice lacking ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium/calmodulin-dependent protein kinase II in the hippocampus. Mol. Brain Res Mol Brain Res. 2000 Mar 10;76(1):142-50.
Takahiro Moriya, Yuko Yoshinobu, Yasuko Kouzu, Akira Katoh, Hiroshi Gomi, Masayuki Ikeda, Tohru Yoshioka, Shigeyoshi Itohara and Shigenobu Shibata , The essential role of GlialFibrillary Acidic Protein (GFAP)-expressing astrocytes in the mouse circadian oscillation under constant lighting condition, J Neurosci Res. 2000 60, 212-218.
Kazumasa Horikawa, Shin-ichi Yokota, Kazuyuki Fuji, Masashi Akiyama, Takahiro Moriya,Hitoshi Okamura and Shigenobu Shibata. Non-photic entrainment by 5-HT1A/7 receptor agonists accompanying with reduction of Per1 and Per2 expression. J Neurosci. 2000 Aug 1;20(15):5867-73.
Yamaguchi S, Mitsui S, Miyake S, Yan L, Onishi H, Yagita K, Suzuki M, Shibata S, Kobayashi M, Okamura H. The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol. 2000 Jul 13;10(14):873-6.
Ikeda M, Sugiyama T, Suzuki K, Moriya T, Shibata S, Katsuki M, Allen CN, Yoshioka T. PLC beta 4-independent Ca2+ rise via muscarinic receptors in the mouse suprachiasmatic nucleus. Neuroreport. 2000 Apr 7;11(5):907-12.
T. Moriya, S. Takahashi, M. Ikeda, K. Suzuki-Yamashita, M. Asai, H. Kadotani, H. Okamura, T. Yoshioka and S. Shibata, N-metyl-D-aspartate receptor subtype 2C is not involved in the circadian oscillation or photic entrainment of the biological clock in mice. J Neurosci Res. 2000 Sep 15;61(6):663-73.
Takahiro Moriya, Yasuko Kouzu, Shigenobu Shibata, Hiroshi Kadotani, , Kohji Fukunaga, Eishichi Miyamoto and TohruYoshioka.,Close linkage between Calcium/ CalmodulinKinase II a/β and NMDA-2A receptors in the lateral amygdala and significance for retrieval of auditory fear conditioning. Eur J Neurosci. 2000 Sep;12(9):3307-14.
Asai M, Ikeda M, Akiyama M, Oshima I, Shibata S, Administration of melatonin in drinking water promotes the phase advance of light-dark cycle in senescence-accelerated mice, SAMR1 but not SAMP8. Brain Res. 2000 Sep 8;876(1-2):220-4.
Moriya T., Horikawa K, Akiyama M, Shibata S,. Correlative association between N-Methyl-D-Aspartate (NMDA) Receptor-Mediated Expression of Period Genes in the Suprachiasmatic Nucleus and Phase Shifts in Behavior with Photic Entrainment of Clock in Hamsters. Mol Pharmacol. 2000 Dec;58(6):1554-62.
Shin-ichi Yokota, Kazumasa Horikawa, Masashi Akiyama, Takahiro Moriya, ShizufumiEbihara, TakuroOhta, and Shigenobu Shibata. Inhibitory Action of Brotizolam on Circadian and Light-induced Per1 and Per2 Expression in the Hamster Suprachiasmatic Nucleus. Br J Pharmacol. 2000 Dec;131(8):1739-47.
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