2020

"Synthesis of Karrikinolide Using the Aldol Type Acetal Addition Reaction"
Kanade Kirita and Seijiro Hosokawa,
J. Org. Chem. 2020, 85(5), 3936-3941.
DOI: 10.1021/acs.joc.9b03195
"Total Synthesis of Exigurin: Ugi Reaction in a Hypothetical Biosynthesis of Natural Products"
Seijiro Hosokawa, Keisuke Nakanishi, Yutaro Udagawa, Mitsutoshi Maeda, Seiya Sato, Keiji Nakano,
Toshiya Masuda and Yoshiyasu Ichikawa
Org. Biomol. Chem. 2020, 18, 687-693.
DOI:10.1039/C9OB02249J

2019

"Synthesis of C3–C21 Segment of Aflastatin A Using Remote Asymmetric Induction Reactions"
Sawato Murakoshi and Seijiro Hosokawa,
Org. Lett. 2019, 21(3), 758-761.
DOI:10.1021/acs.orglett.8b04008
"Synthesis of the C1–C17 Segment of Bafilomycin N"
Haruka Sato and Seijiro Hosokawa,
Synlett 2019, 30(05), 577-580.
DOI:10.1055/s-0037-1611727
"Total Synthesis of PF1163B"
Aakash Sengupta and Seijiro Hosokawa,
Synlett 2019, 30(06), 709-712.
DOI:10.1055/s-0037-1610694
"2-Isopropylbenzimidazole and 2-methylbenzimidazole as bulky proton sources: Stereoselective protonation and application to the synthesis of γ- and δ-lactones "
Aakash Sengupta and Seijiro Hosokawa,
Tetrahedron Letters 2019, 5, 411-414.
DOI:10.1016/j.tetlet.2018.12.044

2018

"Total Syntheses of Stoloniferol B and Penicitol A, and Structural Revision of Fusaraisochromanone"
Tatsuki Ohashi and Seijiro Hosokawa,
Org. Lett. 2018, 20, 3021-3024.
DOI:10.1021/acs.orglett.8b01048
"Total Synthesis and Structural Determination of XR774, a Tyrosine Kinase Inhibitor"
Kuniaki Tatsuta, Daisuke Sekine, Shinichi Hayama, Yasuhiro Kataoka, Shinya Hayashi, and Seijiro Hosokawa,
J. Org. Chem, 83, 13, 7010-7018. DOI:10.1021/acs.joc.7b02997
 "Trimethylphosphine-Promoted Alcoholysis of α,β-Unsaturated Imides and α,β-Unsaturated Esters"
Haruka Sato, Seijiro Hosokawa, Synthesis, 2018, 50, 1343-1349. DOI:10.1055/s-0036-1589162

2017

"Stereoselective Synthesis of Tabtoxinine-β-lactam by Using the Vinylogous Mukaiyama Aldol Reaction with Acetate-Type Vinylketene Silyl N,O-Acetal and α-Keto-β-lactam"
Hirotaka Ejima, Fumihiro Wakita, Ryo Imamura, Takuya Kato, and Seijiro Hosokawa
Organic Letters, 19, (10), 2530-2532, (2017).
DOI:10.1021/acs.orglett.7b00814
 "Remote Asymmetric Bromination Reaction with Vinylketene Silyl N,O-Acetal and Its Application to Total Synthesis of Pellasoren A
Shinji Sekiya, Mao Okumura, Kei Kubota, Tatsuya Nakamura, Daisuke Sekine, and Seijiro Hosokawa Organic Letters, 19, (9), 2394-2397, (2017).
DOI:10.1021/acs.orglett.7b00920
"Syn Selective Vinylogous Mukaiyama Aldol Reaction Using Z,E-Vinylketene N,O-Acetal with Acetals"
Naoya Sagawa, Hiroki Moriya, and Seijiro Hosokawa Organic Letters, 19, (1), 250-253, (2017).
DOI:10.1021/acs.orglett.6b03549
 "Remote Asymmetric Induction Using Acetate-Type Vinylketene Silyl N,O-Acetals
Naoya Sagawa, Haruka Sato, and Seijiro Hosokawa Organic Letters, 19, (1), 198-201, (2017).
DOI:10.1021/acs.orglett.6b03476

2016

 "Synthesis and antileishmanial activity of the core structure of cristaxenicin A
Hitoshi Fumiyama, Tomoko Sadayuki, Yasutaka Osada, Yasuyuki Goto, Yoichi Nakao, Seijiro Hosokawa Bioorganic & Medicinal Chemistry Letters, 26, 4355-4375(2016).
DOI:10.1055/s-0035-1560572
"Stereoselective Alkylation of the Vinylketene Silyl N,O-Acetal and Its Application to the Synthesis of Mycocerosic Acid"
Tatsuya Nakamura, Kei Kubota, Takanori Ieki, and Seijiro Hosokawa Organic Letters, 18 (1), 132-135 (2016).
DOI:10.1016/j.bmcl.2016.06.061
 "Total Synthesis of PDIM A
Tatsuya Nakamura, Hanae Nakagome, Shoichiro Sano, Tomoko Sadayuki, Seijiro Hosokawa Chemistry Letters, 45, (5), 550-551(2016).
DOI:10.1246/cl.160152

2015

"Synthetic Studies on Aculeximycin: Synthesis of C24-​C40 Segment by Kobayashi Aldolization and Epoxide Rearrangements"
Kato, Takuya; Sato, Tomohiko; Kashiwagi, Yuki; Hosokawa, Seijiro Organic Letters, 17 (9), 2274-2277 (2015).
DOI:10.1021/acs.orglett.5b00965
 "Stereoselective Synthesis of the C27-C48 Moiety of Aflastatin A by a Carbohydrate Strategy Using a Tin(II)-Mediated Aldol Reaction
Sawato Murakoshi, Seijiro Hosokawa Synlett, 26 (17), 2437-2441 (2015).
DOI:10.1055/s-0035-1560572

2014

"Stereoselective Acylation of the E,​E-​Vinylketene Silyl N,​O-​Acetal and Its Application to the Synthesis of Khafrefungin"
Takahashi, Yuta; Otsuka, Maiko; Harachi, Mio; Mukaeda, Yuki; Hosokawa, Seijiro Organic Letters, 16 (16), 4106-4109 (2014).
DOI:10.1021/ol501805j
 "Concise synthesis of 6-​formylindolo[3,​2-​b]​carbazole (FICZ)"
Sekine, Daisuke; Okeda, Shota; Hosokawa, Seijiro Chemistry Letters, 43 (12), 1932-1934 (2014).
DOI:10.1246/cl.140843

2013

"Concise Synthesis of Reduced Propionates by Stereoselective Reductions Combined with the Kobayashi Reaction"
Tatsuya Nakamura , Mio Harachi , Takaaki Kano , Yuki Mukaeda , and Seijiro Hosokawa, Organic Letters, 15 (12), 3170-3173 (2013).
DOI:10.1021/ol401406m
 "syn-Selective Kobayashi Aldol Reaction Using Acetals"
Hiroyuki Tsukada, Yuki Mukaeda, and Seijiro Hosokawa, Organic Letters, 15 (3), 678-681 (2013).
DOI:10.1021/ol303519y

2012

"Syn-Selective Kobayashi Aldol Reaction Using the E,E-Vinylketene Silyl N,O-Acetal"
Yuki Mukaeda, Takuya Kato, and Seijiro Hosokawa, Organic Letters, 14 (20), 5298-5301 (2012).
DOI:10.1021/ol3024677
"The first total synthesis of hibarimicinone, a potent v-Src tyrosine kinase inhibitor"
Kuniaki Tatsuta, Tomohiro Fukuda, Tatsuya Ishimori, Rearu Yachi, Shinpei Yoshida, Hiroshi Hashimoto, and Seijiro Hosokawa, Tetrahedron Letters, 53 (4), 422-425 (2012).
DOI:10.1016/j.tetlet.2011.11.062

2011

"The first total synthesis and structural determination of K1115B1s (alnumycins)"
Kuniaki Tatsuta, Sonoko Tokishita, Tomohiro Fukuda, Takaaki Kano, Tadaaki Komiya, and Seijiro Hosokawa, Tetrahedron Letters, 52 (9), 983-986 (2011).

2010

"The first total synthesis of lactonamycin, a hexacyclic antitumor antibiotic"
Kuniaki Tatsuta, Hiroaki Tanaka, Hitomi Tsukagoshi, Takafumi Kashima, and Seijiro Hosokawa, Tetrahedron Letters, 51 (42), 5546-5549 (2010).
"The first total synthesis and structural determination of epi-cochlioquinone A"
Seijiro Hosokawa, Kaoru Matsushita, Shinpei Tokimatsu, Tatsuya Toriumi, Yasuaki Suzuki, and Kuniaki Tatsuta, Tetrahedron Letters, 51 (42), 5532-5536 (2010).
DOI:10.1016/j.tetlet.2010.07.153

2009

"The first total synthesis and structural determination of benzopyrenomycin"
Seijiro Hosokawa, Yuki Mukaeda, Ryo Kawahara, and Kuniaki Tatsuta, Tetrahedron Letters, 50 (48), 6701-6704 (2009).
DOI:10.1016/j.tetlet.2009.09.089
"The first total synthesis of nidulalin A, a dihydroxanthone possessing multiple bioactivities"
Kuniaki Tatsuta, Shusuke Yoshihara, Nobutaka Hattori, Shinpei Yoshida, and Seijiro Hosokawa, J. Antibiot. 62 (8), 469-470 (2009).
"エノラート化学の開発と天然生理活性物質の全合成"
"Development of Enolate Chemistry and Total Syntheses of Bioactive Natural Products"
細川誠二郎, 有機合成化学協会誌, 67 (1), 24-37 (2009).
Seijiro Hosokawa, J. Synth. Org. Chem., Jpn, 67 (1), 24-37 (2009).

2008

" Total Synthesis of an Anti-Helicobacter pylori Agent, Actinopyrone A "
Seijiro Hosokawa, Kazuya Yokota, Keisuke Imamura, Yasuaki Suzuki, Masataka Kawarasaki, Kuniaki Tatsuta, Chem. Asian J. 3 (8), 1415 -1421 (2008)
DOI:10.1002/asia.200800109
" The first total synthesis and structural determination of TMC-264"
Kuniaki Tatsuta, Akiho Furuyama, Tomoe Yano, Yasuaki Suzuki, Takashi Ogura, and Seijiro Hosokawa, Tetrahedron Letters, 49 (25), 4036-4039 (2008).
" Total Synthesis of an Endothelin Converting Enzyme Inhibitor, TMC-66"
Seijiro Hosokawa, Hitoshi Fumiyama, Hisato Fukuda, Tomohiro Fukuda, Masashi Seki, and Kuniaki Tatsuta, Heterocycles, 76 (1), 699-713 (2008).
DOI:10.3987/COM-08-S(N)67

2007

" The first total synthesis and structural determination of (+)-BE-52440A "
Kuniaki Tatsuta, Yoshikazu Suzuki, Tatsuya Toriumi, Yoshiaki Furuya, and Seijiro Hosokawa, Tetrahedron Letters, 48 (45), 8018-8021 (2007).
" The first total synthesis and structural determination of TMC-66"
Seijiro Hosokawa, Hitoshi Fumiyama, Hisato Fukuda, Tomohiro Fukuda, Masashi Seki, and Kuniaki Tatsuta, Tetrahedron Letters, 48 (41), 7305-7308 (2007).
DOI:10.1016/j.tetlet.2007.08.037
" The first total synthesis and structural determination of YCM1008A "
Kuniaki Tatsuta, Takahiro Yamaguchi, Yusuke Tsuda, Yumiko Yamaguchi, Nobutaka Hattori, Hiroshi Nagai, and Seijiro Hosokawa, Tetrahedron Letters, 48 (24), 4187-4190 (2007).
" YCM1008A, a novel Ca2+-signaling inhibitor, produced by Fusarium sp. YCM1008"
Fumito Koizumi, Naomi Fukumitsu, Jinrong Zhao, Ruthada, Chanklan, Tokichi Miyakawa, Shoko Kawahara, Shin Imamoto, Makoto Suzuki, Shingo Kakita, Endang S. Rahayu, Seijiro Hosokawa, Kuniaki Tatsuta, Michio Ichimura, Journal of Antibiotics, 60 (7), 455-458 (2007).
" Total Synthesis of Khafrefungin Using Highly Stereoselective Vinylogous Mukaiyama Aldol Reaction "
Shin-ichi Shirokawa, Mariko Shinoyama, Isao Ooi, Seijiro Hosokawa, Atsuo Nakazaki, and Susumu Kobayashi, Organic Letters, 9 (5), 849-852, (2007).
" The First Total Synthesis of Vinaxanthone, a Fungus Metabolite Possessing Multiple Bioactivities "
Kuniaki Tatsuta, Soko Kasai, Yuki Amano, Takahiro Yamaguchi, Masashi Seki, and Seijiro Hosokawa, Chemistry Letters, 36 (1), 10-11, (2007).

2006

" The First Total Synthesis and Structural Determination of Lagunamycin "
Seijiro Hosokawa, Shoichi Kuroda, Keisuke Imamura, and Kuniaki Tatsuta, Tetrahedron Letters, 47 (35), 6183-6186, (2006).
DOI:10.1016/j.tetlet.2006.06.158
" The First Total Synthesis and Structural Determination of Actinopyrone A "
Seijiro Hosokawa, Kazuya Yokota, Keisuke Imamura, Yasuaki Suzuki nand Kuniaki Tatsuta, Tetrahedron Letters, 47 (30), 5415-5418, (2006).
DOI:10.1016/j.tetlet.2006.05.028
" Enantioselective Total Synthesis of Convolutamydines B and E"
Tomoaki Nakamura, Shin-ichi Shirokawa, Seijiro Hosokawa, Atsuo Nakazaki, and Susumu Kobayashi, Organic Letters, 8 (4), 677-679, (2006).
DOI:10.1021/ol052871p
" Total Synthesis of an Antitubercular Aantibiotic, (+)-Tubelactomicin A "
Seijiro Hosokawa, Masashi Seki, Hisato Fukuda, and Kuniaki Tatsuta, Tetrahedron Letters, 47, 2439-2442, (2006).

2005

" Stereoselective 1,5-rearrangement of vinylketene-N,O-acetals: novel vinylogous Ferrier reaction "
Masaharu Inui, Seijiro Hosokawa, Atsuo Nakazaki, and Susumu Kobayashi, Tetrahedron Letters, 46, 3245-3248, (2005).
" The First Total Synthesis of Trichostatin D "
Seijiro Hosokawa, Takashi Ogura, Takahide Togashi, and Kuniaki Tatsuta, Tetrahedron Letters, 46, 333-337, (2005).
DOI:10.1016/j.tetlet.2004.11.004

2004

" Acetoxyl Group Directed Cyclization Promoted by SmI2: Directing Group Determined Stereocomplementarity "
Toshiyuki Kan, Seijiro Hosokawa, Shinji Nara, Hiroaki Tamiya, Haruhisa Shirahama, Fuyuhiko Matsuda, J. Org. Chem., 69, 8956-8958, (2004).
" Remote Stereoinduction with Vinylketene N,O-acetal "
Shin-ichi Shirokawa, Masato Kamiyama, Tomoaki Nakamura, Masakazu Okada, Atsuo Nakazaki, Seijiro Hosokawa, and Susumu Kobayashi, J. Am. Chem. Soc., 126 (42), 13604-13605, (2004).
DOI:10.1021/ja0465855
" Highly Efficient Total Synthesis of (+)-Citreoviral "
Yoshihisa Murata, Tomoyuki Kamino, Toshiaki Aoki, Seijiro Hosokawa, and Susumu Kobayashi, Angew. Chem. Int. Ed. Engl., 43 (24), 3175-3177, (2004).
DOI:10.1002/anie.200454212

2003

" Stereoselective Construction of a Quaternary carbon Substituted with Multifunctional Groups: Application to the Concise Synthesis of (+)-Ethosuximide "
Tomoaki Abe, Tatsuo Suzuki, Kazuhiko Sekiguchi, Seijiro Hosokawa and Susumu Kobayashi, Tetrahedron Letters, 44(41), 9303-9305, (2003).
"1,3-Rearrangement of Ketene-N,O-acetals "
Tatsuo Suzuki, Masaharu Inui, Seijiro Hosokawa, and Susumu Kobayashi, Tetrahedron Letters, 44(18), 3713-3716, (2003).

~2003

" Stereocontrolled Preparation of 1,2-diol with Quaternary Chiral Center "
Yoshihisa Murata, Tomoyuki Kamino, Seijiro Hosokawa, and Susumu Kobayashi, Tetrahedron Letters, 43(45), 8021-8023, (2002).
DOI:10.1016/S0040-4039(02)01946-9
" Total Synthesis of Madindoline A "
Seijiro Hosokawa, and Susumu Kobayashi, J. Synth. Org. Chem., Jpn, 59(11), 1103-1108, (2001).
有機合成協会誌(pdf) 59 pp1103-1108
" Mirror Image Synthesis of Left Ends of Ciguatoxin and Gambiertoxin 4B "
Seijiro Hosokawa, Minoru Isobe, J. Org. Chem. 64(1), 37-48, (1999)
DOI:10.1021/jo980088n
 " Reductive decomplexation of biscobalthexacarbonyl acetylenes into olefins "
Seijiro Hosokawa, Minoru Isobe, Tetrahedron Letters, 39 (17), 2609-2612, (1998).
DOI:10.1016/S0040-4039(98)00281-0

総説

" Asymmetric Vinylogous Mukaiyama Aldol Reactions using Vinylketene N,O-Acetals in Total Syntheses of Natural Products "
Seijiro Hosokawa, Kuniaki Tatsuta, Mini-Reviews in Organic Chemistry, 5 (1), 1-18 (2008).
" Total Synthesis of Polyketide-Derived Bioactive Natural Products "
Kuniaki Tatsuta, Seijiro Hosokawa, The Chemical Records., 6 (4), 217-233 (2006).
" Total Synthesis of Bioactive Natural Products from Carbohydrates "
Kuniaki Tatsuta, Seijiro Hosokawa, Sci. Tech. Adv. Mater., 7 (5), 397-410 (2006).
" Total Synthesis of Selected Bioactive Natural Products: Illustration of Strategy and Design "
Kuniaki Tatsuta, Seijiro Hosokawa, Chemical Reviews, 105 (12), 4707-4729 (2005).

その他

"天然物合成で活躍した反応 "
竜田 邦明、細川 誠二郎, 有機合成化学協会編、化学同人、2011年, p. 7-8, 135-136, 151-152, 197-198.
(選定委員・著)福山 透、竜田 邦明、林 雄二郎、菅 敏幸、細川 誠二郎、横島 聰
" 天然物の全合成 2000~2008(日本) "
Kuniaki Tatsuta, Seijiro Hosokawa, 有機合成化学協会編、化学同人、2009年, p. 2, 106-107, 125-126, 240-241.
" 抗生物質FR901464の全合成 "
細川 誠二郎, ファルマシア, vol.37 No.7 p.650-651 (2001).
"技と力の全合成 スクリプス研究所Nicolaou研究室 "
細川 誠二郎, 現代化学, (8), 26-28, (2000).