Understanding gut microbiota, one cell at a time

Waseda University scientists devised a novel technique called the single-cell amplified genomes in gel beads sequencing (SAG-gel) platform, which can provide multiple draft genomes of the gut microbiota at once and identify bacteria that respond to dietary fiber at the species level without a need for existing reference genomes. This technique enables exploring gut microbiota one cell at a time.

Their findings were published in Microbiome on January 23, 2020.